Purespring Therapeutics presents preclinical data at the 61st ERA Congress
London— 24 May 2024— Purespring Therapeutics, a pioneering gene therapy company focused on transforming the treatment of kidney diseases, is presenting preclinical data at the 61 st European Renal Association (ERA) Congress , showing that transgenes can be efficiently targeted to podocytes to replace defective genes or to use the podocyte as a protein factory to modulate kidney biology.
- London— 24 May 2024— Purespring Therapeutics, a pioneering gene therapy company focused on transforming the treatment of kidney diseases, is presenting preclinical data at the 61 st European Renal Association (ERA) Congress , showing that transgenes can be efficiently targeted to podocytes to replace defective genes or to use the podocyte as a protein factory to modulate kidney biology.
- The presentation: “A novel podocyte gene therapy enables pathway to clinical translation for the treatment of glomerular diseases” is being presented today at the ERA Congress, taking place in Stockholm, Sweden from 23-26 May.
- This was demonstrated by resolution of severe proteinuria improved serum albumin and reduction in glomerulosclerosis.
- Additional toxicological assessments of renal and other organ function from urine and blood, and post-study histopathological assessments revealed no pre-clinical treatment-related safety concerns.