Hyperoxia

New Study Finds Significant Correlation Between Masimo ORi™ and Arterial Partial Pressure of Oxygen During One-Lung Ventilation

Retrieved on: 
Lunedì, Dicembre 11, 2023
Biotechnology, Surgery, Health, Pharmaceutical, Health Technology, Odds ratio, Samsung Medical Center, De novo, Blood, OLV, Sungkyunkwan University, Hypoxemia, Risk, MASI, Patient, Multimedia, Journal, FDA, Hyperoxia, Oxygen, Blood gas tension, Perioperative, Ori, Oxygen saturation (medicine), Receiver operating characteristic, Medical device, Medical imaging, Anesthesia, ROC

ORi is trended continuously with SpO2 as a unit-less index between 0.00 and 1.00 to extend the visibility of the patient oxygenation beyond SpO2 under supplemental oxygen.

Key Points: 
  • ORi is trended continuously with SpO2 as a unit-less index between 0.00 and 1.00 to extend the visibility of the patient oxygenation beyond SpO2 under supplemental oxygen.
  • During anesthesia, ORi was monitored using Masimo RD rainbow SET® Pulse CO-Oximetry sensors, and blood gas analysis was performed 15 minutes after OLV was initiated.
  • Of the 11 potential predictors for PaO2
  • The researchers concluded, “ORi values during one-lung ventilation were significantly correlated with PaO2 measured simultaneously.

Incheon National University Scientists Develop New Hydrogels for Wound Management

Retrieved on: 
Lunedì, Novembre 6, 2023
DA, Polymerization, Engineering, Water, Catecholamine, Associate, Hyperoxia, Life, Human, Oxygen, Dopamine, Anesthetic, Coagulation, Wound healing, Research, Cell proliferation, Gel, KPA, Regeneration, Accident, Calcium peroxide, Gas, Incheon National University, GOTS, Toxicity, Suture, Infection, Hydrophobic light-activated adhesive, Adhesive, Silk

GWANGJU, South Korea, Nov. 6, 2023 /PRNewswire/ -- Wound management is essential to ensure a speedy and safe recovery, and tissue adhesive patches are an attractive option that can replace sutures and stapling. In a recent study, researchers from Korea developed a new type of gelatin-based tissue adhesive hydrogel that locally generates oxygen through a reaction mediated by calcium peroxide, which improves the adhesiveness of the material and greatly enhances the healing process.

Key Points: 
  • Open wounds, whether caused by accidents or from medical procedures like surgery, require proper management to speed up healing and prevent infections.
  • While sutures and staples are common wound closure methods, they can cause secondary tissue injuries, potentially leaking fluids and gases and requiring anesthetics.
  • Against this backdrop, a team of researchers from Korea, led by Associate Professor Kyung Min Park of Incheon National University set out to find an effective solution to these limitations.
  • The research team has high hopes for the potential of the GOTs to become a cost-effective solution for wound management in a clinical setting.

Masimo ORi™ Granted De Novo as the First and Only FDA-Cleared Noninvasive and Continuous Parameter to Provide Insight into Hyperoxia Under Supplemental Oxygen

Retrieved on: 
Venerdì, Ottobre 13, 2023
Surgery, Medical Devices, Hospitals, Health, Health Technology, Linda, Multimedia, MASI, Desaturation, De novo, US, University of Utah, De novo gene birth, MD, Ori, Motion, Blood gas tension, Apnea, University, Hyperoxia, Intensive care medicine, American Medical Association, FDA, CE marking, Masimo, Oxygen, Oxygen saturation (medicine), Anesthesia & Analgesia, Pulse, Airway management, Patient, Medical device, Compact Disc manufacturing, RD, Anesthesia, Anesthesiology, Pain management

Masimo (NASDAQ: MASI) today announced that ORi™, a noninvasive, continuous parameter designed to provide additional insight into a patient’s oxygen status in the moderate hyperoxic range under supplemental oxygen, has been granted a De Novo by the FDA.

Key Points: 
  • Masimo (NASDAQ: MASI) today announced that ORi™, a noninvasive, continuous parameter designed to provide additional insight into a patient’s oxygen status in the moderate hyperoxic range under supplemental oxygen, has been granted a De Novo by the FDA.
  • Enabled by the multi-wavelength Masimo rainbow® Pulse CO-Oximetry platform, ORi is designed for use in conjunction with oxygen saturation (SpO2) to provide increased resolution of changes in oxygenation under supplemental oxygen.
  • View the full release here: https://www.businesswire.com/news/home/20231013679815/en/
    Without ORi, there is no noninvasive way to monitor oxygenation under supplemental oxygen to manage hyperoxia, or higher than normal oxygenation of arterial blood.
  • By convention, SpO2 is limited to an upper limit of 100%, but oxygenation can rise into hyperoxia when supplemental oxygen is administered.

Researchers Discover How Too Much Oxygen Damages Cells and Tissues

Retrieved on: 
Mercoledì, Marzo 8, 2023
Genome, MD, Protein, Biochemistry, University of California, San Francisco, Gene, SAN, UCSF, Oxygen, Plant, Goldilocks and the Three Bears, Gladstone Institutes, Cell, Enzyme, Obstructive sleep apnea, Reactive oxygen species, CRISPR, Growth, Death, Animal, Non-Euclidean geometry, Molecular Cell, Bacteria, Hyperoxia, DNA, Sulfur, Tissue, Iron, Patient, Hari Krishan Jain, Human, Baek, Stroke, End organ damage, Sleep apnea, Doctor of Philosophy, Seizure, Splenic infarction, Nursing, Pharmaceutical industry, Phosphorus

SAN FRANCISCO, March 8, 2023 /PRNewswire/ -- When it comes to oxygen, you can have too much of a good thing. Breathing air that contains higher levels of oxygen than the usual 21 percent found in Earth's atmosphere can cause organ damage, seizures, and even death in people and animals, particularly if it's in excess of the body's oxygen needs. Until now, however, scientists have mostly speculated about the mechanisms behind this phenomenon, known as oxygen toxicity, or hyperoxia.

Key Points: 
  • Now, researchers at Gladstone Institutes have discovered how excess oxygen changes a handful of proteins in our cells that contain iron and sulfur—a chemical process similar to the rusting of iron.
  • While clinicians have long studied the details of how oxygen shortage impacts cells and tissues (for example, in heart attacks and strokes), the effects of excess oxygen have been relatively understudied.
  • As a result, cells stop functioning correctly and consume even less oxygen, causing a further increase in oxygen levels in the surrounding tissues.
  • "One important takeaway is that hyperoxia is not impacting cells and tissues solely through reactive oxygen species, as many had assumed," says Jain.

Biobarica: Worldwide Leaders in Hyperbaric Treatments

Retrieved on: 
Giovedì, Gennaio 27, 2022
Alternative Medicine, Medical Devices, FDA, Health, Fitness & Nutrition, Physical Therapy, Food, Oxygen, ATA, Technology, Multimedia, Efficiency, Hospital, Hyperbaric medicine, Patient, News, Hyperoxia, Food and Drug Administration, FDA, Diving chamber, Pharmaceutical industry, Medical imaging, Medical device, Hydraulic machinery

Professionals around the world decided to be part of Biobarica and join the largest global network of treatment centers that develop Hyperbaric Oxygen Therapy.

Key Points: 
  • Professionals around the world decided to be part of Biobarica and join the largest global network of treatment centers that develop Hyperbaric Oxygen Therapy.
  • View the full release here: https://www.businesswire.com/news/home/20220127005119/en/
    Biobarica is the leading company in the manufacture of Hyperbaric Chambers, with high therapeutic efficiency.
  • Hyperbaric medicine treatment has achieved customer satisfaction by accelerating patient recovery by 50% and 60% in relation to conventional treatments.
  • It stands out for the unique characteristics that make it the largest and most versatile single-seat hyperbaric chamber of its kind.

Researchers Use Masimo ORi™, Oxygen Reserve Index, to Help Suppress Postoperative Hyperoxia in Patients Undergoing Breast Surgery

Retrieved on: 
Lunedì, Dicembre 14, 2020
Biotechnology, Surgery, Oncology, General Health, Health, Medical devices, Clinical trials, Other Health, Medicine, Clinical medicine, Medical specialties, Masimo, Pulse oximetry, Oxygen saturation, Hyperoxia, Hypoxia, Oxygen therapy, Oxygen, Hypoxic Training Index

Enabled by the multi-wavelength rainbow Pulse CO-Oximetry platform, ORi is provided alongside oxygen saturation (SpO2), a clinically proven Masimo SET pulse oximetry measurement.

Key Points: 
  • Enabled by the multi-wavelength rainbow Pulse CO-Oximetry platform, ORi is provided alongside oxygen saturation (SpO2), a clinically proven Masimo SET pulse oximetry measurement.
  • They divided 50 patients scheduled for breast surgery into a group receiving ORi-based oxygen treatment (group O) and a control group that received conventional postoperative oxygen treatment (group C).
  • Hyperoxia was defined as partial pressure of arterial oxygen (PaO2) > 120 mmHg, and hypoxia as oxygen saturation (SpO2) 94% for more than 1 minute.
  • The researchers concluded, Determining postoperative supplemental oxygen amount using ORi can noninvasively suppress hyperoxia, preventing hypoxia.

New Study Investigates the Utility of Masimo ORi™, Oxygen Reserve Index, As an Indicator to Avoid Hyperoxia During General Anesthesia

Retrieved on: 
Lunedì, Luglio 15, 2019
Biotechnology, General Health, Health, Medical devices, Clinical trials, Other Health, Chemistry, Chemical elements, Medicine, Oxygen, Diving medicine, Respiratory diseases, Respiratory therapy, Hyperoxia, Intensive care medicine, Anesthesia

As an index with a scale between 0.0 and 1.0, ORi can be trended to notify clinicians of changes in a patients oxygen reserve.

Key Points: 
  • As an index with a scale between 0.0 and 1.0, ORi can be trended to notify clinicians of changes in a patients oxygen reserve.
  • The researchers concluded that Hyperoxemia can be detected by observing ORi of patients under general anesthesia, and thus unnecessary administration of high concentration oxygen can possibly be avoided.
  • Yoshida K, Isosu T, Noji Y, Ebana H, Honda J, Sanbe N, Obara S, Murakawa M. Adjustment of oxygen reserve index (ORi) to avoid excessive hyperoxia during general anesthesia.
  • Applegate R, Dorotta I, Wells B, Juma D, Applegate P. The relationship between oxygen reserve index and arterial partial pressure of oxygen during surgery.