Fixed-Dose Combination of Albuterol and Budesonide (PT027) Demonstrated Significant Benefits for Asthma Patients in MANDALA and DENALI Phase III Trials
Retrieved on:
Jeudi, septembre 9, 2021
The trial included 3,132 patients with moderate to severe asthma taking maintenance ICS with or without additional controller medicines.
Key Points:
- The trial included 3,132 patients with moderate to severe asthma taking maintenance ICS with or without additional controller medicines.
- Inflammation is a distinctive feature of asthma and plays a key role in asthma symptoms, exacerbations and deaths.
- Many millions of patients globally rely on their rescue inhaler to alleviate acute symptoms, but this does not treat the underlying inflammation in asthma.
- The MANDALA and DENALI trials demonstrate an albuterol/budesonide rescue inhaler can address inflammation and prevent exacerbations, making PT027 an important potential new treatment option for patients.