Fasting | Jotup

How to maintain a healthy gut microbiome in 2024

Retrieved on:

Lundi, janvier 8, 2024

All of these things also support the gut microbiome – all the microbes that live in your digestive system – but there are some extras to consider if you want to optimise your gut health.

Key Points:

All of these things also support the gut microbiome – all the microbes that live in your digestive system – but there are some extras to consider if you want to optimise your gut health.
It’s widely accepted among those of us who study the gut microbiome that a healthy gut is one that contains a diverse range of microbes and has an effective gut barrier (the lining between your intestine and bloodstream).
Emulsifiers, a common additive in ultra-processed foods, have been found to cause intestinal inflammation and a leaky gut.

Prebiotics and probiotics

Dietary fibre is a good example of a prebiotic, which is defined as a non-digestible food ingredient that can stimulate the growth of good bacteria in the colon.
As the main food source of your gut microbes, it is important to consume enough if you want your microbiome to flourish.

Most prebiotics come from plant foods, so getting a high diversity of plant products in your diet will keep your gut healthy.
This may sound hard to achieve but bear in mind that both good-quality coffee and dark chocolate count.
Probiotics, the live bacteria and yeasts themselves, can be easily consumed through fermented food products, drinks or supplements.

Medication and the microbiome

You may have heard that antibiotics are bad for your gut microbiome, especially those which are “broad spectrum” and will kill off not only harmful bacteria but beneficial ones too.
Staying healthy by prioritising good sleep and managing stress levels is also important, but increasing your intake of both prebiotics and probiotics at this time may lessen the blow of medication on your microbiome.
In the meantime, follow the above advice – it will help you maintain a healthy gut microbiome in 2024 and beyond.

The authors do not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and have disclosed no relevant affiliations beyond their academic appointment.

Witness to the Cultural Development of Beijing @Beijing Central Axis

Retrieved on:

Lundi, janvier 8, 2024

Qiu Zheng, Director of Beijing Central Axis Culture Institute, introduced that the Beijing central axis runs from north to south, consisting of 15 sites such as Yongdingmen, Temple of Heaven, Imperial Palace, Bell and Drum Tower.

Key Points:

Qiu Zheng, Director of Beijing Central Axis Culture Institute, introduced that the Beijing central axis runs from north to south, consisting of 15 sites such as Yongdingmen, Temple of Heaven, Imperial Palace, Bell and Drum Tower.
Most of them are on the central axis, but the Temple of Heaven and the Altar of Agriculture, the Imperial Ancestral Temple and the Altar of the Land and Grain, which are not on the central axis, but close to the east and west sides of the central axis.
They exist because of the central axis, they are an important part of the central axis.
Recently, Yovana, a student from Serbia, came to the Temple of Heaven with several expert teachers from China to learn more about the Beijing central axis.

2024 Food & Beverage Trends Include Mood-Supporting Foods, Function-Focused Hydration, Protein-Packed Snacking, the Rise of AI, and Third-Culture Cuisines

Retrieved on:

Jeudi, janvier 4, 2024

Conversely, more than six in ten (61%) also believe their overall mental and emotional well-being has a significant or moderate impact on their food and beverage choices.

Key Points:

Conversely, more than six in ten (61%) also believe their overall mental and emotional well-being has a significant or moderate impact on their food and beverage choices.
“In 2023 we saw a boom in flavored sparkling water (#WaterTok garnered over 960 million mentions on TikTok!)
That includes beverages that contain “clean caffeine,” drinks to support better sleep, and added pre- and probiotics for gut health.
Actions by the Food and Drug Administration (FDA) are bringing Americans closer to an updated definition of a “healthy” food.

How living like a hunter-gatherer could improve your health

Retrieved on:

Jeudi, janvier 4, 2024

Yet it’s often confusing to know the best way to achieve this, and many aspects of modern, westernised living conspire to keep us from achieving this goal.

Key Points:

Yet it’s often confusing to know the best way to achieve this, and many aspects of modern, westernised living conspire to keep us from achieving this goal.
This suggests there’s much we can learn from hunter-gatherers to improve our lives.

Building connections

Each member contributes, shares equally and belongs to a collective greater than themselves.
According to James Woodburn, an anthropologist who studied the Hadza, tribe members “value their life as hunter-gatherers, they regard it as a wonderful life.
Many aspects of modern society, such as urbanisation, the nuclear family and consumerism, mean many of the connections inherent to hunter-gatherer society have been eroded.
Exercising in green spaces and practising mindfulness are also great ways of connecting with the present and boosting mental health.

Eating well

Diets primarily consist of plant-based foods, such as tubers, berries and fruit that are readily available.
Many studies have shown that plant-based diets and fasting can have many benefits for health.
Here's what the science says
Because hunter-gatherers eat what nature offers, this means their diets consist mainly of whole foods.

Limiting intake of ultra-processed foods and adopting a diet more akin to those followed by hunter-gatherers can help improve your health.

Moving more

Their nomadic lifestyle of hunting and foraging meant they consistently covered distances from six to 16km daily.
Combined with diets high in ultra-processed foods, this means many of us consume more calories each day than we use, leading to weight gain.
We can also benefit from moving more like hunter-gatherers.
Making time to socialise, focusing on getting more plants in our diets and moving more often are all things we can do daily to live more like hunter-gatherers – and look after our health.

David Clayton has received research funding from the British Nutrition Foundation, the Society for Endocrinology, Innovate UK and the Turmeric Co. [email protected] currently receives funding from the National Institute for Health Research, the European Commission and the British Academy.
In the past, he has received grants from the Arts and Humanities Research Council, Economic and Social Research Council, UK Research and Innovation, Department for Health and Social Care and the National Health Service.

Make Your New Year's Resolutions Last with Insights from Dr. Steven Gundry, Featuring Gundry MD Bio Complete 3 Supplement

Retrieved on:

Vendredi, décembre 29, 2023

Fasting, Defecation, Metabolism, Habit, Nutritional science, Weight loss, Capsule, Probiotic, Steven Gundry, Health, Eating, Mitochondrion, Digestion, Energy, Gundry

LOS ANGELES, Dec. 29, 2023 /PRNewswire/ -- As the countdown to the new year begins, so does the tradition of setting resolutions. However, statistics show that by mid-February, many individuals find themselves falling off the wagon. Renowned health expert Dr. Steven Gundry suggests his approach to ensure your resolutions stick: make tiny changes to your routine that can easily evolve into lasting habits.

Key Points:

Supercharge with Supplements: Dr. Gundry recommends incorporating supplements into your daily routine, with a particular emphasis on Gundry MD Bio Complete 3 .
Gundry MD Bio Complete 3 is a triple-pronged gut health powerhouse that contains a blend of probiotics, prebiotics, and postbiotics.
Dr. Gundry, the founder of Gundry MD, advises users to maintain a consistent intake of Gundry MD Bio Complete 3 for at least three months to fully appreciate its potential and achieve optimal outcomes.
Gundry MD Bio Complete 3 can be purchased on the Gundry MD site for the price of $69.95 for a 30-day supply with a 90-day purchase price guarantee.

48% OF CONSUMERS PLAN TO MAKE NEW YEAR’S RESOLUTIONS, NUMERATOR REPORTS

Retrieved on:

Jeudi, décembre 28, 2023

Hobby, Weight loss, Fraction, Mental health, Diet, Weight Watchers, Fasting, Education, Eating

According to a Numerator December 2023 survey, 48% of U.S. consumers plan to set goals for the new year, with 31% still undecided.

Key Points:

According to a Numerator December 2023 survey, 48% of U.S. consumers plan to set goals for the new year, with 31% still undecided.
New Year’s Resolutions 2024 Consumer Sentiment Findings:
Nearly half of consumers plan on making New Year’s resolutions for 2024.
48% of consumers plan to make resolutions, down slightly from 50% last year.
Overarching changes to eating and exercise habits are how consumers plan to accomplish their weight loss goals.

Low-cost Interventions Could Ease the Burden of Diabetes, according to the Journal of American Physicians and Surgeons

Retrieved on:

Mercredi, décembre 13, 2023

Management requires chronic medication use, with the expectation that this will be required life-long, creating a huge burden on medical systems.

Key Points:

Management requires chronic medication use, with the expectation that this will be required life-long, creating a huge burden on medical systems.
Recently, however, novel low-cost noninvasive treatment approaches demonstrate promise for the long-term remission of T2DM symptoms, write Paul Marik , M.D., and colleagues in the winter issue of the Journal of American Physicians and Surgeons.
Abnormalities that contribute to T2DM include insulin resistance, impaired insulin secretion, increased glucose production in the liver, and other factors.
“The suggested protocols need further study, and funding is needed for holistic diabetes management in medical systems.”
The Journal of American Physicians and Surgeons is published by the Association of American Physicians and Surgeons (AAPS), a national organization representing physicians in all specialties since 1943.

Aspargo Laboratories Inc. Announces Completion of Dosing of All Subjects in Sildenafil Oral Suspension Bioavailability Study and Initiation of Dosing in Companion Food-Effect Study

Retrieved on:

Mardi, décembre 5, 2023

Male, ED, Fed, Absorption, Plasma, Sildenafil, Prevalence, Fasting, Tablet, University, Patient, Erectile dysfunction, Pharmaceutical industry

In addition, today the Company announced the initiation of dosing of 38 subjects in two cohorts in the Company’s food effect study, comparing the amount of active drug in plasma after administration of a single oral dose of Sildenafil Oral Suspension (ASP-001) under fasting and fed (following a meal) conditions.

Key Points:

In addition, today the Company announced the initiation of dosing of 38 subjects in two cohorts in the Company’s food effect study, comparing the amount of active drug in plasma after administration of a single oral dose of Sildenafil Oral Suspension (ASP-001) under fasting and fed (following a meal) conditions.
We look forward to providing top-line data from both studies in early 2024.”
Sildenafil Oral Suspension is an oral liquid suspension of sildenafil citrate administered via a metered-dose pump that dispenses 12.5 mg of sildenafil per actuation.
Aspargo uses a metered-dose container that delivers the precise amount of sildenafil citrate per actuation based on patient need.
The discreet and easy-to-carry oral formulation allows the user to customize dosing, with physician direction, and avoid pill splitting or crushing common with the traditional tablet medication.

Understanding Consumer Behavior in the Functional Beverages Sector Amidst Post-Pandemic and Inflationary Challenges - ResearchAndMarkets.com

Retrieved on:

Mercredi, décembre 20, 2023

Food, Beverage, Retail, Online, Fasting, Cleanse, Diet, Health, COVID-19, Table, Intermittency, Drink

Their preference leans toward 'better-for-you' products characterized by attributes such as clean labels, natural and organic ingredients, reduced sugar, low-calorie profiles, and plant-based formulations.

Key Points:

Their preference leans toward 'better-for-you' products characterized by attributes such as clean labels, natural and organic ingredients, reduced sugar, low-calorie profiles, and plant-based formulations.
This report segments the functional beverage market into various categories, offering a granular view that includes Energy and Sports Drinks, Functional Carbonated Drinks, Functional Coffees and Teas, and several others.
It presents consumer demographic and psychographic analyses, market predictions from 2023 through 2027, and the impact of COVID-19 and inflation on consumer choices.
Equipped with tables featuring survey data, marketing photographs, and in-depth narratives, the report provides a thorough exploration of the functional beverage market.

NeuroBo Pharmaceuticals Submits IND Application to the FDA for a Phase 1 Clinical Trial of DA-1726 for the Treatment of Obesity

Retrieved on:

Jeudi, décembre 28, 2023

The IND application supports a Phase 1 clinical trial of DA-1726, a novel, dual oxyntomodulin (OXM) analog agonist that functions as a glucagon-like peptide-1 receptor (GLP1R) and glucagon receptor (GCGR) for the treatment of obesity.

Key Points:

The IND application supports a Phase 1 clinical trial of DA-1726, a novel, dual oxyntomodulin (OXM) analog agonist that functions as a glucagon-like peptide-1 receptor (GLP1R) and glucagon receptor (GCGR) for the treatment of obesity.
"Preclinical evidence shows that DA-1726 reduced food intake while also increasing energy expenditure, which resulted in persistent weight loss in diet-induced obese mice and rats.
Additionally, the administration of DA-1726 resulted in similar weight reduction while consuming more food compared to tirzepatide (Mounjaro™).
Secondary endpoints include the PK of DA-1726, assessed via serum concentrations over time and metabolite profiling at the highest doses of DA-1726.