Hyperkalemia

Kidney Patients Raise National Health Alert on Phosphorus

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星期四, 四月 4, 2024

WASHINGTON, April 4, 2024 /PRNewswire/ -- The American Association of Kidney Patients (AAKP), the oldest and largest independent kidney patient consumer organization in the U.S., is raising public awareness on April 5, National Phosphorus Awareness Day, about the devastating impacts of unmanaged phosphorus levels in individuals with advanced chronic kidney disease (CKD).

Key Points: 
  • Kidney patients are at an increased risk for high phosphorus (termed hyperphosphatemia) due to their decreased kidney function and an inability to excrete excess nutrients, including phosphorus.
  • Kidney patients are medically complex and typically manage multiple co-related health conditions including hyperphosphatemia , hyperkalemia , CKD associated pruritis (CKD-aP) , and more .
  • Kidney patients and all people of goodwill involved in the fight to improve kidney health are making their voices heard by contacting their U.S.
  • Since 1969, The American Association of Kidney Patients has been a patient-led organization driving policy discussions on kidney patient care choice and medical innovation.

Endo Launches Ibuprofen-Famotidine Tablets, Generic Version of DUEXIS®

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星期二, 三月 26, 2024

DUBLIN, March 26, 2024 /PRNewswire/ -- Endo International plc (OTC: ENDPQ) announced today that one of its operating companies, Par Pharmaceutical, Inc., launched ibuprofen-famotidine 800 mg/26.6 mg tablets, a generic version of Amgen's (formerly Horizon Therapeutics) DUEXIS®.

Key Points: 
  • DUBLIN, March 26, 2024 /PRNewswire/ -- Endo International plc (OTC: ENDPQ) announced today that one of its operating companies, Par Pharmaceutical, Inc., launched ibuprofen-famotidine 800 mg/26.6 mg tablets, a generic version of Amgen's (formerly Horizon Therapeutics) DUEXIS®.
  • Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at a greater risk for serious GI events.
  • Ibuprofen and famotidine tablets should not be administered to patients with a history of hypersensitivity to other H2-receptor antagonists.
  • If ibuprofen and famotidine is used in patients with a recent MI, monitor patients for signs of cardiac ischemia.

Endo Launches Ibuprofen-Famotidine Tablets, Generic Version of DUEXIS®

Retrieved on: 
星期二, 三月 26, 2024

DUBLIN, March 26, 2024 /PRNewswire/ -- Endo International plc (OTC: ENDPQ) announced today that one of its operating companies, Par Pharmaceutical, Inc., launched ibuprofen-famotidine 800 mg/26.6 mg tablets, a generic version of Amgen's (formerly Horizon Therapeutics) DUEXIS®.

Key Points: 
  • DUBLIN, March 26, 2024 /PRNewswire/ -- Endo International plc (OTC: ENDPQ) announced today that one of its operating companies, Par Pharmaceutical, Inc., launched ibuprofen-famotidine 800 mg/26.6 mg tablets, a generic version of Amgen's (formerly Horizon Therapeutics) DUEXIS®.
  • Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at a greater risk for serious GI events.
  • Ibuprofen and famotidine tablets should not be administered to patients with a history of hypersensitivity to other H2-receptor antagonists.
  • If ibuprofen and famotidine is used in patients with a recent MI, monitor patients for signs of cardiac ischemia.

Sun Pharma Launches WINLEVI® (clascoterone) Cream 1% Connected TV (CTV) Ad Campaign with Dr. Sandra Lee (a.k.a. "Dr. Pimple Popper")

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星期三, 三月 6, 2024

WINLEVI is the first and only FDA-approved topical acne treatment available in the U.S. that targets sebum production in the skin.

Key Points: 
  • WINLEVI is the first and only FDA-approved topical acne treatment available in the U.S. that targets sebum production in the skin.
  • "We are thrilled to continue our collaboration with Dr. Sandra Lee, whose persona as 'Dr.
  • Pimple Popper' fits well with our use of humorous and relatable content to connect with teens.
  • Additionally, edema, stinging, and burning occurred in >3% of patients and were reported in a similar percentage of subjects treated with vehicle.

NCH's Success Story at HIMSS24: Patient-Centric Alerts Boost Physician Experience, Patient Safety, and Leapfrog CPOE Test Results

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星期五, 三月 1, 2024

SOUTH SAN FRANCISCO, Calif., March 1, 2024 /PRNewswire/ -- FDB (First Databank, Inc.), the leading provider of drug knowledge that helps healthcare professionals make precise decisions, announces the success of its collaboration with NCH (Naples Comprehensive Health) in Southwest Florida. NCH has leveraged FDB solutions to optimize medication decision support, making alerts more meaningful and relevant to clinicians while significantly reducing overall alert volume.

Key Points: 
  • NCH has leveraged FDB solutions to optimize medication decision support, making alerts more meaningful and relevant to clinicians while significantly reducing overall alert volume.
  • In transitioning to a new EHR system, NCH physicians experienced a shift in their workflow, encountering non-critical-level medication decision support alerts for the first time.
  • The medication CDS optimization initiative has also contributed to NCH's improvement in its Leapfrog CPOE test results.
  • This partnership underscores NCH's commitment to enhancing patient safety and mitigating physician frustration associated with irrelevant alerts.

This salt alternative could help reduce blood pressure. So why are so few people using it?

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星期二, 一月 30, 2024

Excess salt (sodium) increases the risk of high blood pressure so everyone with hypertension is advised to reduce salt in their diet.

Key Points: 
  • Excess salt (sodium) increases the risk of high blood pressure so everyone with hypertension is advised to reduce salt in their diet.
  • It can be used just like regular salt and most people don’t notice any important difference in taste.
  • Switching to potassium-enriched salt is feasible in a way that cutting salt intake is not.

What is potassium-enriched salt?

  • Potassium-enriched salts replace some of the sodium chloride that makes up regular salt with potassium chloride.
  • They’re also called low-sodium salt, potassium salt, heart salt, mineral salt, or sodium-reduced salt.

What is the evidence?


We have strong evidence from a randomised trial of 20,995 people that switching to potassium-enriched salt lowers blood pressure and reduces the risks of stroke, heart attacks and early death. The participants had a history of stroke or were 60 years of age or older and had high blood pressure.
An overview of 21 other studies suggests much of the world’s population could benefit from potassium-enriched salt. The World Health Organisation’s 2023 global report on hypertension highlighted potassium-enriched salt as an “affordable strategy” to reduce blood pressure and prevent cardiovascular events such as strokes.

What should clinical guidelines say?

  • We teamed up with researchers from the United States, Australia, Japan, South Africa and India to review 32 clinical guidelines for managing high blood pressure across the world.
  • While many guidelines recommend increasing dietary potassium intake, and all refer to reducing sodium intake, only two guidelines – the Chinese and European – recommend using potassium-enriched salt.

Why do so few people use it?

  • Few people know a simple switch to potassium-enriched salt can help lower blood pressure and reduce the risk of a stroke and heart disease.
  • Several Australian retailers stock potassium-enriched salt but there is usually only one brand available, and it is often on the bottom shelf or in a special food aisle.


A 2021 review found potassium-enriched salts were marketed in only 47 countries and those were mostly high-income countries. Prices ranged from the same as regular salt to almost 15 times greater. Even though generally more expensive, potassium-enriched salt has the potential to be highly cost effective for disease prevention.

Preventing harm

  • People with serious kidney disease are already advised to avoid regular salt and to avoid foods high in potassium.
  • No harm from potassium-enriched salt has been recorded in any trial done to date, but all studies were done in a clinical setting with specific guidance for people with kidney disease.
  • In some countries, potassium-enriched salt is recommended to the entire community because the potential benefits are so large.

What will happen next?

  • We are working with the taskforce to update Australian hypertension management guidelines, and to promote the new guidelines to health professionals.
  • The next switch to iodised and potassium-enriched salt offers at least the same potential for global health gains.
  • But we need to make it happen in a fraction of the time.
  • Alta Schutte receives funding from the National Health and Medical Research Council of Australia, the Medical Research Future Fund, and NSW Health.
  • She is Company Secretary of the Australian Cardiovascular Alliance, Board Member of Hypertension Australia, and Co-Chair of the National Hypertension Taskforce of Australia.

Human medicines European public assessment report (EPAR): Entresto, sacubitril,valsartan, Date of authorisation: 19/11/2015, Revision: 19, Status: Authorised

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星期二, 一月 2, 2024

Human medicines European public assessment report (EPAR): Entresto, sacubitril,valsartan, Date of authorisation: 19/11/2015, Revision: 19, Status: Authorised

Key Points: 


Human medicines European public assessment report (EPAR): Entresto, sacubitril,valsartan, Date of authorisation: 19/11/2015, Revision: 19, Status: Authorised

Human medicines European public assessment report (EPAR): Neparvis, sacubitril,valsartan, Date of authorisation: 26/05/2016, Revision: 19, Status: Authorised

Retrieved on: 
星期二, 一月 2, 2024

Human medicines European public assessment report (EPAR): Neparvis, sacubitril,valsartan, Date of authorisation: 26/05/2016, Revision: 19, Status: Authorised

Key Points: 


Human medicines European public assessment report (EPAR): Neparvis, sacubitril,valsartan, Date of authorisation: 26/05/2016, Revision: 19, Status: Authorised

Physician Executive Leader Shares Clinician-Friendly Tech Adoption Playbook at CHIME23 Fall Forum

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星期三, 十一月 8, 2023

PHOENIX, Nov. 8, 2023 /PRNewswire/ -- A physician executive leader from a long-time customer of FDB (First Databank, Inc.), the leading provider of drug knowledge that helps healthcare professionals make precise decisions, will share real-world lessons on how to earn clinician buy-in and long-term engagement in health IT projects large and small, even during a time of historic staffing challenges.

Key Points: 
  • "Many organizations today are wary of introducing changes to providers' workflows," said Dr. Levick, who has built his clinician-friendly tech-adoption playbook since 2000.
  • Dr. Levick led numerous health IT projects over two decades that required clinician buy-in and adoption – including an Epic EHR implementation.
  • Yet smaller, incremental tech improvements to an existing EHR, such as implementing FDB Targeted Medication Warnings ™ to optimize select medication safety alerts, require change management steps, too.
  • Dr. Levick also conducted a deep data analysis of clinician behaviors to determine which alerts were being ignored the most.

New Interim, Real-World Data Provides Additional Insights on Hyperkalemia and Safety of Kerendia® (finerenone) for Patients with Chronic Kidney Disease Associated with Type 2 Diabetes

Retrieved on: 
星期六, 十一月 4, 2023

Bayer today announced new interim, real-world data on Kerendia® (finerenone) that complement the hyperkalemia and safety data in its pivotal trials.

Key Points: 
  • Bayer today announced new interim, real-world data on Kerendia® (finerenone) that complement the hyperkalemia and safety data in its pivotal trials.
  • The data was presented at the American Society of Nephrology’s (ASN) Kidney Week 2023.
  • Kerendia is the first non-steroidal, selective mineralocorticoid receptor (MR) antagonist to demonstrate dual cardiorenal risk reduction in adult patients with chronic kidney disease (CKD) and type 2 diabetes (T2D).
  • “Kerendia provides healthcare providers with a treatment option to slow chronic kidney disease progression and reduce cardiovascular risk in patients with CKD associated with T2D,” said Robert Perkins, MD, Vice President, Cardiovascular & Renal, Bayer.