Laboratory

Nasa to overhaul mission returning samples from Mars – here’s why it must and will go ahead

Retrieved on: 
星期二, 四月 23, 2024

This has led to some anxiety among space scientists, who view the Mars Sample Return (MSR) mission as a cornerstone of plans to explore the Solar System.

Key Points: 
  • This has led to some anxiety among space scientists, who view the Mars Sample Return (MSR) mission as a cornerstone of plans to explore the Solar System.
  • But when you consider what’s at stake, scientifically and politically, it seems highly likely that Nasa will push ahead with the mission to make it a success.
  • One key conclusion of the Nasa review is that MSR was established with unrealistic budget and schedules.
  • Esa is also unlikely to want to lose the scientific investment it has already made in MSR.

Huge scientific importance


So why does the space science community regard MSR as so important? Partly because the technologies are a stepping stone to future human exploration. For instance, the mission needs an ascent vehicle to launch the samples into orbit for capture by another spacecraft.

  • That capture in Mars orbit of a football-sized return capsule is one of the key technical challenges of MSR.
  • Esa is taking a major part in this and leads the return orbiter development.
  • This stage will deploy the very best equipment that we scientists have in laboratories across the world.
  • But these financial savings come with a scientific cost.

Chinese rivalry

  • The Apollo programme was given impetus by cold war rivalry with the Soviet Union.
  • The Chinese Space Agency wants to launch in 2028, with separate lander and ascent vehicle launches.
  • In 2020, I argued that an era of new Chinese collaboration with the west could be possible.


John Bridges receives funding from the UK Space Agency for NASA-ESA Mars Sample Return planning groups tasked with identifying the best techniques to analyse returned samples, and the closest terrestrial analogues for these samples.

A new measure of firm-level competition: an application to euro area banks

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星期四, 四月 18, 2024

Abstract

Key Points: 
    • Abstract
      This paper extends Boone (2008) by introducing a competition measure at the individual
      firm level rather than for an entire market segment.
    • We apply this extended Boone indicator to individual bank-level competition
      in the loan market in the four largest euro area countries and Austria.
    • Our new measure of firm-level competition enriches and complements
      other competition measures and provides a promising starting point for future market
      power analyses.
    • The only measure among non-structural measures that is based on the
      concept of competition as a process of rivalry is the Boone (2008) indicator.
    • We introduce
      a new performance measure of competition by extending the Boone indicator to the
      individual firm level.
    • Introduction
      The ability to reliably measure competition is valuable to researchers, analysts, and
      policymakers, especially antitrust authorities, financial supervisors, and central banks.
    • One broad
      category of indicators often used to measure competition are structural competition
      measures, such as static concentration measures, and dynamic measures, e.g., entry and
      exit rates.
    • Out of these measures, the only measure based on the
      concept of competition as a process of rivalry is the Boone indicator.
    • This study introduces a new performance measure of competition by extending the
      Boone indicator to the individual firm level.
    • It thus measures the
      increase in profits in percent of one percentage point increase in efficiency, with marginal
      costs as measure of efficiency.
    • We extend the theoretical
      underpinning of the measurement of competition for the entire market of Boone (2008) by
      a new measure of individual firm-level competition.
    • A concern of the literature is the gap
      between the practical application and the theoretical framework of Boone (2008).
    • We introduce within the same theoretical
      framework a new measure of competition on firm level, the MRP.
    • Our new
      measure significantly augments the antitrust evaluative framework by shedding light on
      whether a merger results in a less competitive market.
    • Our novel indicator focuses on
      firms? incentives to enhance their relative efficiency, as manifested in the elasticity
      between relative profits and efficiency.
    • However, an inefficient firm that is foreclosed could be more
      competitive than the larger efficient firm that relies on its scale economies.
    • Our new metric of competition unveils
      banks? ability to influence their profitability in the short term by cutting costs relative to
      their peers.
    • The new MRP indicator provides the ability to assess the impact
      of individual banks? competitiveness on their interest rate-setting behaviour in loan
      markets.
    • Incorporating this information promises a more refined understanding of the impact and
      timing of monetary policy rates changes on the real economy.
    • Section 3 introduces within the Boone
      (2008) theoretical framework our new measure of individual firm-level competition,
      including the interpretation of the MRP.
    • Section 4 provides an application of our new
      ECB Working Paper Series No 2925

      6

      individual firm-level competition measure to the loan market.

    • The StructureConduct-Performance paradigm (SCP) provides a traditional framework in the field of
      industrial organization for analysing competition behaviour in markets.
    • Concentrated
      markets ease the possibilities to collude implicitly or explicitly and therefore concentrated
      markets result in higher prices and profits.
    • For example, a tougher competition
      setup may lead to a reallocation of market shares, potentially forcing some firms to exit
      the market.
    • This approach gives firms? strategic behaviour
      central stage and focuses on the strategic interaction on prices and quantities, known as
      conjectural variation.
    • Another measure from
      this strand of literature is the H-statistic developed by Panzar and Rosse (1987).
    • The only competition measure from this performance literature where competition is the
      outcome from a process of rivalry is the Boone indicator.
    • A continuous and monotonically increasing relationship exists between
      RPD and the level of competition if firms are ranked by decreasing efficiency.
    • (2013) compare the Boone indicator with the price-cost margin
      and conclude that the profit elasticity is a more reliable measure of competition.
    • The high
      elasticity of profits to efficiency unequivocally indicates that the high market shares and
      therefore high profits are due to high efficiency.
    • A firm that quickly passes changes to the input prices is seen as a price
      taker with little market power.
    • Indicators of competition tend to measure different phenomenon and may provide
      conflicting messages, as reported for European banking by Carbo et al.
    • Application 2: Test the ?quiet life? and related market structure hypotheses using the
      MRP as competition or market structure measure.
    • Data
      Our application to individual bank-level competition in the euro area loan market uses
      balance sheet and income statement data from the Moody?s Analytics BankFocus for the
      calendar years 2013-2020.
    • As such, most publications
      on competition in the euro area includes the largest four member states.
    • Due to these restrictions the database was reduced to an unbalanced panel of up to 1862
      banks (depending on the year) from five euro area countries.
    • Application 1: Measure bank competition using MRP
      Looking at the distribution of the MRP for individual banks (Fig.
    • A similar finding for the four largest euro area countries as a group is
      reported in Carbo et al.
    • Application 2: Test of market structure hypotheses using MRP
      Our new measure of individual-bank competition can be used to test market structure
      theories.
    • Euro area banks? market power,
      lending channel and stability: the effects of negative policy rates, European Central Bank
      Working Paper, 2790 (February).
    • A
      new approach to measuring competition in the loan markets of the euro area, Applied
      Economics, 43 (23), 3155?3167.
    • Impact of bank competition on the interest rate pass-through in the euro area, Applied
      Economics, 45 (11), 1359?1380.

Setting A New Security Benchmark: Kudelski IoT's Semiconductor Alliances Redefine IoT Provisioning

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星期三, 四月 10, 2024

Setting A New Security Benchmark: Kudelski IoT's Semiconductor Alliances Redefine IoT Provisioning

Key Points: 
  • Setting A New Security Benchmark: Kudelski IoT's Semiconductor Alliances Redefine IoT Provisioning
    Premier integration with Microchip, and collaborative partnerships with ST Microelectronics, Infineon, and Silicon Labs radically simplify a critical IoT security requirement.
  • Kudelski IoT libraries are integrated with semiconductor partner tools to enable device manufacturers to personalize their products in the factory or in the field.
  • Hardy Schmidbauer, Senior Vice President at Kudelski IoT, said, “For many IoT device manufacturers, security provisioning is today a laborious manual process that is prone to error, seriously compromising the security of individual devices, or even of a manufacturer’s whole chain of security.
  • By partnering with top IC manufacturers, Kudelski IoT is making provisioning a simpler, more automated, and secure process than ever before.

EQS-News: Medios acquires Dutch market leader in pharmaceutical compounding services

Retrieved on: 
星期三, 四月 10, 2024

Ceban is the Dutch market leader in compounding and has growing market positions in Belgium and Spain.

Key Points: 
  • Ceban is the Dutch market leader in compounding and has growing market positions in Belgium and Spain.
  • The purchase price for 100% of Ceban shares includes a cash component of €235.3 million and 1.7 million Medios shares.
  • The acquisition of Ceban gives Medios an outstanding position in the Dutch pharmaceutical market.
  • Ceban has a market leading position in pharmaceutical compounding in the Netherlands, a top-3 position in Belgium and a top-5 position in Spain.

NJIT Aims to Be an Innovation Nexus Under Its New Strategic Plan

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星期二, 四月 9, 2024

The plan, NJIT Makes An Innovation Nexus, identifies six priorities, spells out the university’s mission to be a leader in research, innovation and entrepreneurship, and reaffirms its core values, including collaboration, social responsibility, diversity and sustainability.

Key Points: 
  • The plan, NJIT Makes An Innovation Nexus, identifies six priorities, spells out the university’s mission to be a leader in research, innovation and entrepreneurship, and reaffirms its core values, including collaboration, social responsibility, diversity and sustainability.
  • At the same time, NJIT will focus on creating a holistic campus environment and helping graduates realize their career goals.
  • “Innovation is at the core of what we do,” NJIT President Teik C. Lim said.
  • Another key player here is the New Jersey Innovation Institute, an NJIT corporation that turns great ideas into new businesses.

Wyss Institute’s AminoX project receives funding from Northpond Labs to accelerate innovation in protein-based therapeutics

Retrieved on: 
星期一, 四月 8, 2024

This is the fourth Wyss project selected by Northpond Labs for additional funding.

Key Points: 
  • This is the fourth Wyss project selected by Northpond Labs for additional funding.
  • The Laboratory has previously funded the Wyss’ eRNA (now being commercialized by EnPlusOne Biosciences ), SomaCode , and Lab-on-a-Molecule projects.
  • “The AminoX platform has the potential to transform our ability to develop differentiated protein-based therapeutics by significantly expanding the vocabulary of building blocks that can be incorporated into biologics at high throughput.
  • We are thrilled that the AminoX team’s journey to the market will be accelerated by this support,” said Angelika Fretzen, Ph.D., M.B.A., the Wyss Institute’s Technology Translation Director & Chief Operating Officer.

Predicine Introduces PredicineCARE™ NGS Kit for Global Clinical Trials, CDx Development and Patient Testing

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星期五, 四月 5, 2024

HAYWARD, Calif., April 05, 2024 (GLOBE NEWSWIRE) -- Predicine, Inc., a leading molecular insights company, announced the release of its innovative PredicineCARE™ NGS Kit. This offering presents a research-use-only (RUO) next-generation sequencing (NGS) kit packaged for genomic profiling across various cancers, facilitating global applications in clinical trials, companion diagnostics (CDx) development, and patient testing.

Key Points: 
  • HAYWARD, Calif., April 05, 2024 (GLOBE NEWSWIRE) -- Predicine, Inc., a leading molecular insights company, announced the release of its innovative PredicineCARE™ NGS Kit.
  • This offering presents a research-use-only (RUO) next-generation sequencing (NGS) kit packaged for genomic profiling across various cancers, facilitating global applications in clinical trials, companion diagnostics (CDx) development, and patient testing.
  • This newly introduced PredicineCARE™ NGS kit integrates a comprehensive, state-of-the-art NGS assay capable of detecting point mutations, indels, fusions, amplifications, and deletions in key cancer-associated genes.
  • “Predicine’s centralized global lab network coupled with the decentralized kitted offering provides a standardized approach to support clinical trials, CDx development and patient testing on a global scale.”

Koryx Copper Intersects 168.60 Metres at 0.40% Cu Eq Including Multiple 2 m Intersections >1.00% Cu Eq and 34.00 m at 0.73% Cu Eq Including 2 m at 2.28% Cu Eq

Retrieved on: 
星期四, 四月 4, 2024

VANCOUVER, British Columbia, April 04, 2024 (GLOBE NEWSWIRE) -- Koryx Copper Inc. ("Koryx" or “the Company") (TSX-V: KRY) announces the third assay results from its current drilling program at its Haib Copper project in southern Namibia.  The Company’s latest four drill holes continue to confirm that the deposit can deliver high grades over substantial widths within the known historical resource.

Key Points: 
  • CuEq (copper equivalent) has been used to express the combined value of copper and molybdenum and is provided for illustrative purposes only.
  • Also half-way up the southern slope it too was positioned to close the sample spacing in this part of Pit1.
  • HM39 was drilled west of and parallel to HM34 and was positioned to close the sample spacing in this direction.
  • Over time, it has seen several transformations including shearing and faulting events that appear to have further concentrated Cu and Mo.

NurExone Reports Fourth Quarter and Year Ended December 31, 2023 Financial Results and Provides Company Update

Retrieved on: 
星期二, 四月 2, 2024

TORONTO and HAIFA, Israel, April 02, 2024 (GLOBE NEWSWIRE) -- NurExone Biologic Inc. (TSXV: NRX) (Germany: J90) (the “Company” or “NurExone”), a pioneering biopharmaceutical company, developing regenerative medicine therapies, today provided a business update and reported financial results for the fourth quarter and financial year ended December 31, 2023.

Key Points: 
  • TORONTO and HAIFA, Israel, April 02, 2024 (GLOBE NEWSWIRE) -- NurExone Biologic Inc. (TSXV: NRX) (Germany: J90) (the “Company” or “NurExone”), a pioneering biopharmaceutical company, developing regenerative medicine therapies, today provided a business update and reported financial results for the fourth quarter and financial year ended December 31, 2023.
  • For the fourth quarter of 2023, expenses were US$0.31 million, compared to US$0.39 million in the previous year.
  • For the fourth quarter of 2023, expenses were US$0.40 million, compared to US$0.46 million in the previous year.
  • For the fourth quarter of 2023, expenses were US$0.02 million, compared to US$0.17 million in the previous year.

Hamilton Thorne Reports Record Revenue and EBITDA for the Quarter and Year Ended December 31, 2023

Retrieved on: 
星期三, 三月 27, 2024

Results of Operations for the Year ended December 31, 2023

Key Points: 
  • Results of Operations for the Year ended December 31, 2023
    Hamilton Thorne sales increased 16% to $67,225,476 for the year-ended December 31, 2023, an increase of $9,047,409 from $58,178,067 during the previous year.
  • Consumable sales in 2023 outpaced the Company’s overall growth despite being affected by the recall of certain products by one of the Company’s contract manufacturers.
  • We are expecting first quarter 2024 reported revenues of between $19.0 to 19.4M, with organic growth for the quarter of approximately 8%.
  • Financial Statements and accompanying Management Discussion and Analysis for the periods are available on www.sedar.com and the Hamilton Thorne website.