Endocrine system

Spruce Biosciences Announces Topline Results from CAHmelia-203 in Adult Classic CAH and CAHptain-205 in Pediatric Classic CAH

Retrieved on: 
Wednesday, March 13, 2024
Biotechnology, Pharmaceutical, Health, GC, Obesity, Endocrinology, Clinical professor, Associate, Risk, Patient, GCS, Mayo Clinic, Androgen, Șaeș, CAH, Endocrine system, Safety, Workforce, Medical director, ACTH, Pharmaceutical industry

Preliminary pharmacokinetic analysis suggests that tildacerfont is cleared more rapidly in children than in adult CAH patients.

Key Points: 
  • Preliminary pharmacokinetic analysis suggests that tildacerfont is cleared more rapidly in children than in adult CAH patients.
  • 70% of patients with elevated baseline A4 values (16 of 23 patients) demonstrated an A4 reduction at week 4.
  • “The CAHptain-205 study results demonstrate safety and tolerability in pediatric CAH patients with weight-adjusted tildacerfont doses up to 200mg daily.
  • An archived copy of the call will be available on the events section of the company’s investor relations website for approximately 90 days.

The Inner Circle Acknowledges, Hank C. Hill as a Pinnacle Life Member

Retrieved on: 
Monday, January 29, 2024
Surgical oncology, Philosophy, Neoplasm, Patient, Annals of Surgical Oncology, Research, Endocrine system, Sarcoma, Radiation, ABS, General surgery, Mentorship, Dance, Health, Multimedia, Knowledge, Music, Inner circle, Surgeon, National Research Service Award, Society, University, MD Anderson Cancer Center, Cancer, Skin, Gastrointestinal tract, Harlem Hospital Center, Esophagus, NIH, Liver, Stomach, Rectum, T-32, Morehouse School of Medicine, Breast, Tennis, Education, Publication, Pancreas, Endoscopy, Nursing

BROOKSVILLE, Fla., Jan. 29, 2024 /PRNewswire/ -- Prominently featured in The Inner Circle, Hank C. Hill is acknowledged as a Pinnacle Life Member for his contributions to the field of Surgical Oncology.

Key Points: 
  • BROOKSVILLE, Fla., Jan. 29, 2024 /PRNewswire/ -- Prominently featured in The Inner Circle, Hank C. Hill is acknowledged as a Pinnacle Life Member for his contributions to the field of Surgical Oncology.
  • Dr. Hill pursued higher education at the Brooklyn Campus of Long Island University where he earned his Bachelor of Science degree in Biology/Pre-Med.
  • Anderson Cancer Center in Houston, where he earned a surgical oncology research fellowship certificate in tumor biology.
  • Aside from his professional pursuits, Dr. Hill enjoys traveling, dancing (soca, reggae, reggaeton, R&B), and listening to music.

Beta-thalassemia Market to Witness Upsurge in Growth During the Study Period (2019-2032), Evaluates DelveInsight | Leading Companies - Vertex Pharmaceuticals, CRISPR Therapeutics, Agios Pharmaceuticals, Celgene, Forma Therapeutics

Retrieved on: 
Wednesday, January 17, 2024
Vertex Pharmaceuticals, Patient, Biologics license application, Therapy, Endocrine system, TGF, Heart, LAS, HBA, Spleen, Diagnosis, Anemia, Mouse, Thalassemia, Beta thalassemia, HB, CBC, RBC, Pharmacosmos, Disease, Iron overload, TDT, EU4, FDA, Blas, Prevalence, Liver, Novo Nordisk, PDUFA, Red blood cell, CRISPR Therapeutics, Hemoglobin A, Cell, Iron, Pharmaceutical industry

LAS VEGAS, Jan. 17, 2024 /PRNewswire/ -- DelveInsight's Beta-thalassemia Market Insights report includes a comprehensive understanding of current treatment practices, beta-thalassemia emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan].

Key Points: 
  • According to DelveInsight's analysis, the market size for beta-thalassemia across the 7MM is expected to grow with a significant CAGR by 2032.
  • The promising beta-thalassemia therapies in the pipeline include CTX001, EDIT-301, Mitapivat, ACE-536, Panobinostat, Etavopivat tablets, and others.
  • In September 2023, Pharmacosmos has initiated a Phase II trial of SP-420 in patients with transfusion-dependent β-thalassemia.
  • In June 2023, FDA accepted the Biologics License Application (BLAs) of exagamglogene autotemcel (exa-cel) for transfusion-dependent beta thalassemia (TDT).

Beta-thalassemia Market to Witness Upsurge in Growth During the Study Period (2019-2032), Evaluates DelveInsight | Leading Companies - Vertex Pharmaceuticals, CRISPR Therapeutics, Agios Pharmaceuticals, Celgene, Forma Therapeutics

Retrieved on: 
Wednesday, January 17, 2024
Vertex Pharmaceuticals, Patient, Biologics license application, Therapy, Endocrine system, TGF, Heart, LAS, HBA, Spleen, Diagnosis, Anemia, Mouse, Thalassemia, Beta thalassemia, HB, CBC, RBC, Pharmacosmos, Disease, Iron overload, TDT, EU4, FDA, Blas, Prevalence, Liver, Novo Nordisk, PDUFA, Red blood cell, CRISPR Therapeutics, Hemoglobin A, Cell, Iron, Pharmaceutical industry

LAS VEGAS, Jan. 17, 2024 /PRNewswire/ -- DelveInsight's Beta-thalassemia Market Insights report includes a comprehensive understanding of current treatment practices, beta-thalassemia emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan].

Key Points: 
  • According to DelveInsight's analysis, the market size for beta-thalassemia across the 7MM is expected to grow with a significant CAGR by 2032.
  • The promising beta-thalassemia therapies in the pipeline include CTX001, EDIT-301, Mitapivat, ACE-536, Panobinostat, Etavopivat tablets, and others.
  • In September 2023, Pharmacosmos has initiated a Phase II trial of SP-420 in patients with transfusion-dependent β-thalassemia.
  • In June 2023, FDA accepted the Biologics License Application (BLAs) of exagamglogene autotemcel (exa-cel) for transfusion-dependent beta thalassemia (TDT).

National Korea Maritime and Ocean University Researchers Explore the Impact of Microplastics and Toxin Exposure on Goldfish

Retrieved on: 
Thursday, January 11, 2024
Endocrine system, BAP, Toxicology, Health, DNA, Biochemistry, DNA repair, Plastic, Travel, Goldfish, Toxicity, Food chain, Pharmacology, Microplastics, Aquaculture

The presence of microplastics, ranging in size from 100 nanometers to 5 millimeters, is particularly concerning.

Key Points: 
  • The presence of microplastics, ranging in size from 100 nanometers to 5 millimeters, is particularly concerning.
  • Another aspect of microplastic pollution, often overlooked but equally dangerous, is their ability to absorb and carry harmful chemicals, such as persistent organic pollutants.
  • Understanding the extent of toxicity and threat posed by the combined impact of exposure to microplastics and other pollutants is, therefore, important.
  • In a recent study now, researchers led by Dr. Cheol Young Choi from National Korea Maritime and Ocean University explored the impact of microplastic and BaP exposure on freshwater goldfish (Carassius auratus), who were exposed to BaP and microplastics individually and in combination, to understand their exposure effects.

MANGOCEUTICALS TO INTRODUCE “PRIME”, POWERED BY KYZATREX®️ (CIII TESTOSTERONE UNDECANOATE CAPSULES), FOR AN FDA APPROVED ORAL TESTOSTERONE REPLACEMENT THERAPY (TRT) PRODUCT

Retrieved on: 
Wednesday, December 13, 2023
Liver, Marketing, Hypogonadism, Risk, PRIME, FDA, TRT, WCS, Telehealth, Absorption, Fatigue, Health, Softgel, Site, SHGB, Conditional sentence, Obesity, Lymphatic system, DTC, Patient, Endocrine system, Erectile dysfunction, Pharmaceutical industry

KYZATREX, a prescription drug that is used to treat adult men who have low or no testosterone levels due to certain medical conditions, is one of only three FDA approved TRT treatments that is delivered orally--as opposed to the traditional, invasive, and inconvenient injection-based drug delivery protocol. KYZATREX delivers testosterone in a softgel capsule that is absorbed primarily via the lymphatic system, avoiding liver toxicity.

Key Points: 
  • KYZATREX delivers testosterone in a softgel capsule that is absorbed primarily via the lymphatic system, avoiding liver toxicity.
  • Testosterone deficiency is often first recognized through symptoms of fatigue or low energy, decreased sex drive, lower muscle mass and many other negative downstream impacts.
  • PRIME, powered by KYZATREX, can help men restore Testosterone to normal levels and improve how they feel.
  • KYZATREX marks a shift in the treatment paradigm and a meaningful opportunity for patients seeking to restore optimal testosterone levels.

Former Twin Valley VT Student Suing Monsanto for PCB Contamination

Retrieved on: 
Thursday, December 21, 2023
Government, School, Student, Endocrine system, Parent, PCB, Polychlorinated biphenyl, Cancer, Non-Hodgkin lymphoma, Public, EPA, Burlington High School, United States Navy, Milberg, Lymphoma, History, Printed circuit board

WILMINGTON, Vt., Dec. 21, 2023 /PRNewswire/ -- A woman who attended Twin Valley Elementary School in Wilmington, Vermont claims in a lawsuit that she was exposed to toxic Polychlorinated Biphenyls (PCBs) at the school manufactured by Monsanto and developed health problems, including lymphoma, as a result. Her attorneys from Milberg Coleman Bryson Phillips Grossman ("Milberg") are also looking to represent others with PCB-related injuries linked to Vermont schools.

Key Points: 
  • Monsanto began making PCBs nearly 100 years ago and manufactured commercial PCBs that were used in schools like Twin Valley through the 1970s.
  • Plaintiff Kristy Crawford, who attended Twin Valley Elementary from 1982 to 1990, has been diagnosed with non-Hodgkin lymphoma and reproductive issues.
  • In 2020, the Vermont Department of Health reported PCB contamination at Burlington High School, where PCB levels in some areas were ten times higher than EPA recommended indoor air levels.
  • We want you to know that we hear your concerns about possible PCB exposure, and we're here for you."

Kanazawa University research: Researchers define a nanopipette fabrication protocol for high resolution cell imaging

Retrieved on: 
Tuesday, August 22, 2023
Kanazawa University, Takahashi, Quartz, Communication, Analytical chemistry, SICM, Noise, Endocytosis, Cell, Nagoya University, Homeostasis, Hormone, Microvillus, Seminal vesicles, HeLa, Glass, Endocrine system, Microscope

KANAZAWA, Japan, Aug. 22, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Analytical Chemistry how to produce nanopipettes that reliably provide nanoscale resolution scanning ion conductance microscopy images of living cells.

Key Points: 
  • KANAZAWA, Japan, Aug. 22, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Analytical Chemistry how to produce nanopipettes that reliably provide nanoscale resolution scanning ion conductance microscopy images of living cells.
  • Now researchers led by Yasufumi Takahashi at Kanazawa University's Nano LSI and Nagoya University have devised a protocol for reproducibly fabricating nanopipettes with the preferred geometry for high quality imaging.
  • Scanning ion conductance microscopy (SICM) uses a nanopipette to control the nanopipette-samples distance using an ion current as feedback signal.
  • Nanopipette Fabrication Guidelines for SICM Nanoscale Imaging, Analytical Chemistry August 20, 2023.

Kanazawa University research: Researchers define a nanopipette fabrication protocol for high resolution cell imaging

Retrieved on: 
Tuesday, August 22, 2023
Kanazawa University, Takahashi, Quartz, Communication, Analytical chemistry, SICM, Noise, Endocytosis, Cell, Nagoya University, Homeostasis, Hormone, Microvillus, Seminal vesicles, HeLa, Glass, Endocrine system, Microscope

KANAZAWA, Japan , Aug. 22, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Analytical Chemistry how to produce nanopipettes that reliably provide nanoscale resolution scanning ion conductance microscopy images of living cells.

Key Points: 
  • KANAZAWA, Japan , Aug. 22, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Analytical Chemistry how to produce nanopipettes that reliably provide nanoscale resolution scanning ion conductance microscopy images of living cells.
  • Now researchers led by Yasufumi Takahashi at Kanazawa University's Nano LSI and Nagoya University have devised a protocol for reproducibly fabricating nanopipettes with the preferred geometry for high quality imaging.
  • Scanning ion conductance microscopy (SICM) uses a nanopipette to control the nanopipette-samples distance using an ion current as feedback signal.
  • Nanopipette Fabrication Guidelines for SICM Nanoscale Imaging, Analytical Chemistry August 20, 2023.

Global Sun Care Cosmetics Market Set to Reach $16.11 Billion by 2030, Driven by Rising Demand for Organic and Cruelty-Free Products - ResearchAndMarkets.com

Retrieved on: 
Monday, August 7, 2023
Cosmetics, Retail, Online, Zinc oxide, Face, Organic Sunscreen, Skin cancer, Ageing, SPF, Badger, Woman, Research, Burn, Tanning, Neck, USD, Formaldehyde, Traction, Specialty store, Distribution, Toluene, Convention (norm), Sunburn, Sunbather (album), Skin, Endocrine system

The global sun care cosmetics market size is expected to reach USD 16.11 billion by 2030, registering a CAGR of 8.3% over the forecast period.

Key Points: 
  • The global sun care cosmetics market size is expected to reach USD 16.11 billion by 2030, registering a CAGR of 8.3% over the forecast period.
  • The sales of sun care cosmetics are largely driven by brand awareness, shopping frequency, and expenditure capability of different buyers.
  • The adoption of sustainable products made without any chemicals is rising.
  • Over the past few years, sun care cosmetics have been gaining popularity among people of all ages, particularly the millennial population.