Angewandte Chemie

Beyond Lithium-ion: Hydrogel's Promising Role in Future Battery Technologies and More

Retrieved on: 
Thursday, October 19, 2023

By methylating the structural polymer of hydrogels, they successfully prevented salt precipitation, resulting in improved battery capacity and cycling performance.

Key Points: 
  • By methylating the structural polymer of hydrogels, they successfully prevented salt precipitation, resulting in improved battery capacity and cycling performance.
  • This breakthrough has far-reaching implications for the future of battery technology, especially in the context of the global push for cost-effective and eco-friendly alternatives to lithium-ion batteries.
  • This report predicts that hydrogels will play a pivotal role in future energy storage solutions, ensuring better performance, stability, and security within battery systems.
  • In conclusion, "Hydrogels: Future Technologies and Markets 2024-2044" is an indispensable resource for those seeking to navigate the evolving landscape of hydrogel technologies.

Just 3 Nobel Prizes cover all of science – how research is done today poses a challenge for these prestigious awards

Retrieved on: 
Friday, September 29, 2023

Today, and for the past 15 years, I’m a full-time historian of chemistry.

Key Points: 
  • Today, and for the past 15 years, I’m a full-time historian of chemistry.
  • Every October, when the announcements are made of that year’s Nobel laureates, I examine the results as a chemist.
  • And all too often, I share the same response as many of my fellow chemists: “Who are they?
  • I am not suggesting that these Nobel laureates are undeserving – quite the opposite.
  • What does this trend reveal about the Nobel Foundation and its award strategies in response to the growth of science?

A gradual evolution in the Nobel Prizes

    • Several years ago, chemist-historian-applied mathematician Guillermo Restrepo and I collaborated to study the relationship of scientific discipline to the Nobel Prize.
    • Each year, the Nobel Committee for chemistry studies the nominations and proposes the recipients of the Nobel Prize in chemistry to its parent organization, the Royal Swedish Academy of Sciences, which ultimately selects the Nobel laureates in chemistry (and physics).
    • We found a strong correlation between the disciplines of the members of the committee and the disciplines of the awardees themselves.
    • Restrepo and I concluded: As go the expertise, interests and the disciplines of the committee members, so go the disciplines honored by the Nobel Prizes in chemistry.

Not letting labels be limiting

    • And so, chemists do mind that the Nobel Prize in chemistry has morphed into the Nobel Prize in chemistry and the life sciences.
    • Since the Nobel Prizes were first awarded in 1901, the community of scientists and the number of scientific disciplines have grown tremendously.
    • Even chemistry as a discipline has grown dramatically, pushing outward its own scholarly boundaries, and chemistry’s achievements continue to be astounding.
    • And there just are not enough Nobel Prizes to go around to all the deserving.

Kanazawa University research: Locking and unlocking molecular structures on demand

Retrieved on: 
Monday, February 27, 2023

KANAZAWA, Japan, Feb. 27, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned — a discovery that may lead to an enhanced functionality of rotaxanes as building blocks for molecular machines.

Key Points: 
  • KANAZAWA, Japan, Feb. 27, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned — a discovery that may lead to an enhanced functionality of rotaxanes as building blocks for molecular machines.
  • Rotaxanes are molecules with a two-component structure: a dumbbell-shaped part (the 'axle') threaded through a ring-like part (the 'wheel').
  • Shigehisa Akine, Yoko Sakata, and colleagues from Kanazawa University have now developed a new approach for controlled rotaxane dissociation and formation.
  • Shigehisa Akine, Yoko Sakata, and colleagues from Kanazawa University have now studied the formation and dissociation process of a palladium-containing rotaxane.

Kanazawa University research: Locking and unlocking molecular structures on demand

Retrieved on: 
Monday, February 27, 2023

KANAZAWA, Japan, Feb. 27, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned — a discovery that may lead to an enhanced functionality of rotaxanes as building blocks for molecular machines.

Key Points: 
  • KANAZAWA, Japan, Feb. 27, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned — a discovery that may lead to an enhanced functionality of rotaxanes as building blocks for molecular machines.
  • Rotaxanes are molecules with a two-component structure: a dumbbell-shaped part (the 'axle') threaded through a ring-like part (the 'wheel').
  • Shigehisa Akine, Yoko Sakata, and colleagues from Kanazawa University have now developed a new approach for controlled rotaxane dissociation and formation.
  • Shigehisa Akine, Yoko Sakata, and colleagues from Kanazawa University have now studied the formation and dissociation process of a palladium-containing rotaxane.

Novel Protective Layer for Catalysts Developed by GIST Scientists Improves Life and Performance

Retrieved on: 
Thursday, January 19, 2023

GWANGJU, South Korea, Jan. 19, 2023 /PRNewswire/ -- Green hydrogen is hydrogen fuel that is produced using environment-friendly methods. Water electrolysis is one of the primary methods of producing green hydrogen. Here, electrical energy generated using renewable energy sources, such as solar panels or wind energy, is used to drive a water-splitting reaction in an electrochemical cell to produce hydrogen and oxygen. However, this reaction requires the use of expensive catalysts, which increases the cost of green hydrogen, making it unviable. Using nickel–iron (Ni–Fe) catalysts at the anode is a possible solution, but these catalysts tend to corrode and get deactivated due to the oxygen released at the anode of the water-splitting cell.

Key Points: 
  • However, this reaction requires the use of expensive catalysts, which increases the cost of green hydrogen, making it unviable.
  • So, we developed an Ni–Fe-based catalyst with a tetraphenylporphyrin (TPP) protection layer.
  • The TPP layer was able to minimize the dissolution of Fe during the oxygen evolution reaction and thus, increase the life and performance of the catalyst."
  • The TPP protection layer was also seen to increase the redeposition of Fe atoms back on to the catalyst.

PureTech’s LYT-300 (Oral Allopregnanolone) Demonstrates Oral Bioavailability, Tolerability and GABAA Receptor Target Engagement in Healthy Volunteers

Retrieved on: 
Monday, December 19, 2022

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20221219005209/en/
    PureTech announced topline results for LYT-300 (oral allopregnanolone), a therapeutic candidate in development for neurological and neuropsychological conditions.
  • The results show that oral administration of LYT-300 achieved blood levels of allopregnanolone at or above those associated with therapeutic benefit and results in exposure-dependent target engagement of GABAA receptors.
  • The impact of LYT-300 on b-EEG and other markers of GABAA target engagement were also assessed.
  • PureTech completed a Phase 1 clinical trial of LYT-300 in 2022, which demonstrated oral bioavailability, tolerability and GABAA receptor target engagement in healthy volunteers.

PureTech Announces New Therapeutic Candidate, LYT-310, an Oral Form of Cannabidiol (CBD) Leveraging PureTech’s Glyph™ Platform

Retrieved on: 
Wednesday, November 30, 2022

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20221130005402/en/
    PureTech announced the nomination of a new therapeutic candidate, LYT-310, which is an oral cannabidiol (CBD) prodrug and the second therapeutic candidate developed from PureTechs Glyph platform to be advanced toward the clinic.
  • The nomination of LYT-310 is an exciting expansion of PureTechs Glyph technology, said Daniel Bonner, Ph.D., Vice President at PureTech Health.
  • Glyph is PureTechs synthetic lymphatic-targeting chemistry platform which is designed to employ the lymphatic systems natural lipid absorption and transport process to enable the oral administration of certain therapeutics.
  • A second therapeutic candidate, LYT-310 (oral cannabidiol), is expected to enter the clinic in Q4 of 2023.

OTI Lumionics and UBC Demonstrate Quantum Computing Methods to be Effective in Simulating OLED Display Material Properties

Retrieved on: 
Monday, March 14, 2022

In this work, we set out to demonstrate that quantum computing methods could be better at simulating the properties of materials used in the best displays found in consumer electronics, said OTIs CEO Michael Helander.

Key Points: 
  • In this work, we set out to demonstrate that quantum computing methods could be better at simulating the properties of materials used in the best displays found in consumer electronics, said OTIs CEO Michael Helander.
  • We developed new quantum computing methods to address this need by better simulating key properties of the emitter materials used in OLED displays.
  • The findings from the collaborative research clearly indicate that quantum computing methods can have a powerful advantage in computational materials design.
  • OTI is the first to develop computing methods for industrial relevant materials design and apply them to commercial problems.

Lygos Announces Key Leadership Appointments

Retrieved on: 
Friday, August 27, 2021

These appointments underscore Lygos recent growth as we steadily increase our offerings of high-quality sustainable organic acids and cannabinoid ingredients, stated Eric Steen, PhD, CEO of Lygos, Photons scientific and legal acumen, in addition to his proven track record of driving business priorities, will continue to help position Lygos for long-term success in this dynamic and evolving market.

Key Points: 
  • These appointments underscore Lygos recent growth as we steadily increase our offerings of high-quality sustainable organic acids and cannabinoid ingredients, stated Eric Steen, PhD, CEO of Lygos, Photons scientific and legal acumen, in addition to his proven track record of driving business priorities, will continue to help position Lygos for long-term success in this dynamic and evolving market.
  • Prior to joining Lygos in 2018, he worked at an American Lawyer 100 firm and as the Director of IP at Threshold Pharmaceuticals.
  • Lygos has created a full-stack biological engineering platform focused on organic acid specialty ingredients, health & wellness ingredients, including cannabinoids and bio-monomers.
  • Lygos and the Lygos logo are trademarks of Lygos, Inc. Any other brands may be trademarks of their respective holders.