Virus

ALVR Shareholders Who Lost Money Should Contact Robbins LLP for Information About the AlloVir, Inc. Class Action

Retrieved on: 
Saturday, February 10, 2024

For more information, submit a form , email Aaron Dumas, Jr., or give us a call at (800) 350-6003.

Key Points: 
  • For more information, submit a form , email Aaron Dumas, Jr., or give us a call at (800) 350-6003.
  • Specifically, AlloVir said it was discontinuing the posoleucel Phase 3 studies after pre-planned analyses concluded they wouldn’t meet their primary endpoints.
  • What Now: Similarly situated shareholders may be eligible to participate in the class action against AlloVir, Inc. Shareholders who want to act as lead plaintiff for the class should contact Robbins LLP.
  • A lead plaintiff is a representative party acting on behalf of other class members in directing the litigation.

This is how tobacco damages our cells

Retrieved on: 
Friday, February 9, 2024

With the countless studies available today on the effects of tobacco use, we should have no trouble convincing ourselves and others of how harmful it is.

Key Points: 
  • With the countless studies available today on the effects of tobacco use, we should have no trouble convincing ourselves and others of how harmful it is.
  • The cells that make up our tissues, organs and body systems are sensitive to the effects of external toxic agents, many of which can be found in tobacco.
  • Many smokers not only accept this, but also ignore the serious danger it poses to the people around them.

Initial effects in the mouth and pharynx

  • When tobacco smoke enters our body, the first cells to receive it are in the mouth, nose and throat.
  • These effects on the immune system are also linked to a higher likelihood of developing cancer.
  • We also cannot forget that tobacco smoke robs us of our sense of taste and smell, leaving an almost continuous bitter taste in the mouth.

Lung damage

  • Furthermore, due to the direct damage caused by tobacco on the tissue that maintains the structure of the lungs, the bronchi and bronchioles become blocked, generating symptoms similar to suffocation.
  • As if that were not enough, people with COPD are also more likely to develop cardiovascular disease, and lung cancer.

Black tar and macrophages

  • We can cast our minds back to the previous image of my father’s pipe, black and sticky with tar.
  • It so happens that the lungs are rich in macrophages – special cells that play a key role in our immune systems by reacting to attacks, producing inflammatory responses.
  • These cells end up ingesting the tar from tobacco, and they eventually die loaded with this substance which builds up and gives a smoker’s lungs their characteristic blackened appearance.

Nicotine’s effects on neurons: dependence and addiction

  • As with any other compound that stimulates neurotransmitter receptors, permanent stimulation desensitises neurons.
  • This means that the neurons reduce the number of receptors, or change their sensitivity to the stimulant.
  • This desensitisation process can lead not only to nicotine dependence, but also to other diseases such as memory loss.


Guillermo López Lluch is a member of the Spanish Society of Cell Biology, the Spanish Society of Biochemistry and Molecular Biology, the Spanish Society of Geriatrics and Gerontology, the Society for Free Radical Research and the International Coenzyme Q10 Association. The research carried out by the author is financed by public funds from the Spanish Government or the Autonomous Government of Andalusia.

Gut microbiome: meet Asaccharobacter celatus – the brain health bug

Retrieved on: 
Friday, February 9, 2024

Research over recent years also suggests our gut bacteria may have a role in helping us maintain our brain health as we age.

Key Points: 
  • Research over recent years also suggests our gut bacteria may have a role in helping us maintain our brain health as we age.
  • My own preliminary research suggests one gut bug in particular called Asaccharobacter celatus (A celatus) could be useful.

Cognitive impairment and dementia

  • Worryingly, this often progresses to more severe impairment of brain function known as dementia.
  • Dementia affects more than 55 million people around the world, and projections suggest this number will increase to 82 million by 2030.

How gut bacteria could help

  • The bacteria in our gut perform functions that benefit our overall health.
  • A celatus, along with certain other bacteria, is capable of producing a compound known as equol.
  • These bacteria make equol from a compound called daidzein, which is found in soy products including soy milk, tofu and tempeh.
  • In many cases, we can influence the make-up of our gut bacteria through our diet, and this appears to be true for A celatus.
  • Read more:
    Gut bacteria rewind ageing brain in mice

    However, other research has shown consumption of soy foods in the diet has no effect on cognitive function.

  • All this suggests that, alongside the bacteria, we already have in our gut microbiome, what we eat could be equally important.

My research

  • This relates to complex cognitive tasks we perform daily, including doing maths in our head, or reorganising the day’s tasks in our mind when something unexpectedly changes.
  • This research appears promising, but we need more evidence to confirm the potential benefits of both A celatus bacteria and soy foods in helping older people maintain their brain health as they age.
  • Each week we will look at a different microbe and bring you the most up-to-date research on them.
  • Nathan Nuzum currently works at University College Cork as part of APC Microbiome and receives funding from the European Union’s Horizon 2020 Research and Innovation Programme under the INSPIRE COFUND Marie Skłodowska Curie grant agreement No.
  • The unpublished/original work referred to in this article was conducted at Deakin University as part of Dr. Nathan Nuzum's PhD.
  • Dr. Nuzum's PhD supervisors for this work includes his primary supervisor Dr. Helen Macpherson, and his co-supervisors (in alphabetical order) Drs.

Sugary handshakes are how cells talk to each other − understanding these name tags can clarify how the immune system works

Retrieved on: 
Thursday, February 8, 2024

Unlike people, cells perform these handshakes using the diverse range of sugar molecules coating their surface like trees covering a landscape.

Key Points: 
  • Unlike people, cells perform these handshakes using the diverse range of sugar molecules coating their surface like trees covering a landscape.
  • Handshakes between these sugar molecules, or glycans, trigger cells to react in specific ways toward each other, such as escape, ignore or destroy.

What are glycans?

  • The vast number of possible glycan structures that can be built from connecting these sugar molecules together allows glycans to store rich information.
  • Glycans are chemically bonded to proteins and lipids on the surface of red blood cells.
  • Notably, the surface of type A red blood cells have glycans that differ from the glycans on the surface of type B and type O red blood cells.
  • For example, distinctive glycoproteins cover the surface of the viruses that cause COVID-19, HIV and H1N1 influenza and help them infect cells.
  • Glycolipids also coat many bacteria, allowing them to stick to their hosts and protect them from viruses and immune cells.

How do cells read glycans?

  • Found on surfaces of certain immune cells, these lectins deliver the glycans to proteins on other immune cells that can now selectively destroy any viruses or cells that carry that glycan.
  • For example, these lectins recognize glycans on the surfaces of cancer cells and direct other immune cells to eliminate these cancer cells.
  • Another type of lectin called siglecs are found on surfaces of immune cells and help them distinguish self from nonself, that is, between the cells that make up the body and the cells that are foreign to the body.
  • The bacterial glycans in the vaccine trigger an immune response when immune cells recognize the glycans as foreign threats.

Examining every sugar molecule

  • Comprehensively extracting all the information stored in glycans is very difficult because there isn’t currently technology able to analyze the complex and diverse structures of glycans.
  • Individual glycans are composed of sugar molecules in unique arrangements, but current analytical tools can only simultaneously analyze many glycans.


My lab is confronting this challenge by developing imaging technology that can analyze the structure of glycans by imaging each individual molecule. Essentially, we’re developing a technique to open the jar and study every single candy one at a time. In the long run, my team aspires to unveil how these glycans present themselves to the proteins that recognize them and, finally, reveal the very language that cells use to express themselves.
Kelvin Anggara works for the Max Planck Institute for Solid State Research and receives funding from the European Research Council under Project GlycoX (101075996).

Virtual Internet Announces Virtual 5G for Android now with Anti-Malware

Retrieved on: 
Thursday, February 8, 2024

SINGAPORE and SAN JOSE, Calif., Feb. 8, 2024 /PRNewswire/ -- Virtual Internet announced the completion of a comprehensive Anti-Malware capability for Virtual Internet Services. This new Anti-Malware suite has been added to both Virtual 5G and Virtual Home Office.

Key Points: 
  • SINGAPORE and SAN JOSE, Calif., Feb. 8, 2024 /PRNewswire/ -- Virtual Internet announced the completion of a comprehensive Anti-Malware capability for Virtual Internet Services.
  • This new Anti-Malware suite has been added to both Virtual 5G and Virtual Home Office.
  • Virtual 5G with Anti-Malware is also being offered with an enhanced suite direct from Virtual Internet.
  • Virtual 5G is the only 5G service that is natively designed to communicate over a 5G Global Broadband Network that is itself multiply encrypted.

Merck Manuals Details Key Facts to Know About Multiple Sclerosis

Retrieved on: 
Wednesday, February 7, 2024

The cause of MS is unknown, but some studies point to early exposure to certain viruses in triggering the immune system to attack the body's own tissue.

Key Points: 
  • The cause of MS is unknown, but some studies point to early exposure to certain viruses in triggering the immune system to attack the body's own tissue.
  • Individuals without a formal diagnosis may be tempted to ignore their illness, especially if symptoms have waned, says Levin.
  • But he adds it's crucial to work to uncover the cause of symptoms and discuss them with a healthcare professional.
  • Based on the condition and its symptoms, neurologists can guide patients toward the most effective treatments and medications.

Global Professional Hand Hygiene Market Outlook & Forecast Report 2023-2028 Featuring Key Vendors - P&G, Cleenol Group, GOJO Industries, Kimberly-Clark, Kutol, Medline Industries, Neogen - ResearchAndMarkets.com

Retrieved on: 
Wednesday, February 7, 2024

The global professional hand hygiene market is led by several prominent vendors, including 3M, GOJO Industries, Kimberly-Clark, Kutol, P&G, Medline Industries, Neogen, and many others.

Key Points: 
  • The global professional hand hygiene market is led by several prominent vendors, including 3M, GOJO Industries, Kimberly-Clark, Kutol, P&G, Medline Industries, Neogen, and many others.
  • The rapidly changing technological environment could adversely affect vendors as customers expect continual innovations and upgrades in professional hand hygiene products.
  • North America held the most prominent global professional hand hygiene market share, responsible for over 30% of the revenue in 2022.
  • The global professional hand hygiene market includes hand lotions/creams, handwash, hand sanitizers, hand scrubs, and wipes.

Coeptis Therapeutics to Pursue Phase 2 Program Using Proprietary First-in-Class Allogeneic NK Cell Therapy for the Treatment of Viral Infections

Retrieved on: 
Wednesday, February 7, 2024

WEXFORD, Pa., Feb. 7, 2024 /PRNewswire/ -- Coeptis Therapeutics Holdings, Inc. (Nasdaq: COEP) (the "Company" or "Coeptis"), a biopharmaceutical company developing innovative cell therapy platforms for cancer and infectious diseases, today announced plans to pursue DVX201, its proprietary allogeneic stem cell expansion and directed differentiation platform of unmodified natural killer (NK) cell therapy, as an antiviral treatment addressing various respiratory viral infections that lead to hospitalization, including the "tripledemic" of influenza, COVID-19 and respiratory syncytial virus (RSV).

Key Points: 
  • DVX201 is produced by pooling CD34+ cells isolated from multiple cord blood donations to increase lot size and immune system diversity.
  • Importantly, doses undergo stringent testing including a potency assay before treatment, to assess their ability to kill virally infected cells.
  • Additionally, DVX201 does not contain T-cells, which significantly reduces the possibility for major rejection by patients, which is a major concern for some cell therapy products.
  • DVX201, the first-ever allogeneic, cord-blood derived NK cell therapy generated from pooled donor CD34+ HSPC cells, has the potential to offer significant support to patients and to our strained healthcare system."

Smart Home Devices Market to Reach $707.2 Billion by 2032 at 21.5% CAGR: Allied Market Research

Retrieved on: 
Wednesday, February 7, 2024

NEW CASTLE, Del, Feb. 7, 2024 /PRNewswire/ -- Allied Market Research published a report, titled, "Smart Home Devices Market by Component (Solution and Services) and Type (Lighting Control, Security Access Control, HVAC Control, Entertainment & Other Controls, Smart Kitchen, Home Appliances, Smart Furniture, and Others): Global Opportunity Analysis and Industry Forecast, 2023-2032" According to the report, the global smart home devices market generated $101.6 billion in 2022 and is estimated to reach $707.2 billion by 2032, exhibiting a CAGR of 21.5% from 2023 to 2032. The report offers a detailed analysis of changing market trends, top segments, key investment pockets, value chains, regional landscapes, and competitive scenarios.

Key Points: 
  • Users may manage different parts of their houses with voice-activated smart home gadgets without having to touch surfaces, which lowers the chance of the virus spreading.
  • Because temperature and humidity levels affect the survival and spread of viruses, smart thermostats assist maintain a clean and healthy atmosphere.
  • In high-touch areas, smart appliances that reduce the need for physical contact and promote hygiene, including voice-activated kitchen appliances and touchless faucets, are essential.
  • Integrating health monitoring devices, such fitness trackers or smartwatches, may provide useful information about a user's health and wellbeing.

Smart Home Devices Market to Reach $707.2 Billion by 2032 at 21.5% CAGR: Allied Market Research

Retrieved on: 
Wednesday, February 7, 2024

NEW CASTLE, Del, Feb. 7, 2024 /PRNewswire/ -- Allied Market Research published a report, titled, "Smart Home Devices Market by Component (Solution and Services) and Type (Lighting Control, Security Access Control, HVAC Control, Entertainment & Other Controls, Smart Kitchen, Home Appliances, Smart Furniture, and Others): Global Opportunity Analysis and Industry Forecast, 2023-2032" According to the report, the global smart home devices market generated $101.6 billion in 2022 and is estimated to reach $707.2 billion by 2032, exhibiting a CAGR of 21.5% from 2023 to 2032. The report offers a detailed analysis of changing market trends, top segments, key investment pockets, value chains, regional landscapes, and competitive scenarios.

Key Points: 
  • Users may manage different parts of their houses with voice-activated smart home gadgets without having to touch surfaces, which lowers the chance of the virus spreading.
  • Because temperature and humidity levels affect the survival and spread of viruses, smart thermostats assist maintain a clean and healthy atmosphere.
  • In high-touch areas, smart appliances that reduce the need for physical contact and promote hygiene, including voice-activated kitchen appliances and touchless faucets, are essential.
  • Integrating health monitoring devices, such fitness trackers or smartwatches, may provide useful information about a user's health and wellbeing.