Hypnotics

Eisai To Present Latest Data of Lemborexant at 35th Annual Sleep Meeting (SLEEP2021)

Wednesday, June 9, 2021 - 3:31am

TOKYO, June 9, 2021 - (JCN Newswire) - Eisai Co., Ltd. announced today that a total of 5 poster presentations including the latest data on its in-house discovered orexin receptor antagonist lemborexant (product name: DAYVIGO) will be given at the 35th annual meeting of the Associated Professional Sleep Societies (SLEEP 2021), to be held virtually from June 10 to 13, 2021.

Key Points: 
  • TOKYO, June 9, 2021 - (JCN Newswire) - Eisai Co., Ltd. announced today that a total of 5 poster presentations including the latest data on its in-house discovered orexin receptor antagonist lemborexant (product name: DAYVIGO) will be given at the 35th annual meeting of the Associated Professional Sleep Societies (SLEEP 2021), to be held virtually from June 10 to 13, 2021.
  • Major poster presentations include the results of a study evaluating next-dose transition from zolpidem to lemborexant for insomnia treatment (Poster Numbers: #335 and #337).
  • Eisai considers neurology a therapeutic area of focus.
  • Eisai strives to create innovative products in therapeutic areas with high unmet medical needs as soon as possible, and will further contribute to addressing the diverse needs of, as well as increasing the benefits provided to, those living with neurological diseases and their families.

North America Cough Syrup Market Report 2021: Increasing Cases of Respiratory Issues are Providing Lucrative Opportunities - Forecast to 2026 - ResearchAndMarkets.com

Thursday, May 20, 2021 - 5:08pm

b'The "North America Cough Syrup Market By Product, By Age Group, By Distribution Channel, By Country, Growth Potential, Industry Analysis Report and Forecast, 2020 - 2026" report has been added to ResearchAndMarkets.com\'s offering.\nThe increasing cases of respiratory issues are providing lucrative opportunities for the cough syrup market.

Key Points: 
  • b'The "North America Cough Syrup Market By Product, By Age Group, By Distribution Channel, By Country, Growth Potential, Industry Analysis Report and Forecast, 2020 - 2026" report has been added to ResearchAndMarkets.com\'s offering.\nThe increasing cases of respiratory issues are providing lucrative opportunities for the cough syrup market.
  • Moreover, the rising population of old age people along with increasing air pollution are driving the growth of the market.
  • However, the misuse of cough syrup coupled with the strict rules & regulations by the government will restrict the market growth.
  • Moreover, the increasing disposable income of people in emerging nations will also contribute to the rising growth of the global cough syrups market.

Europe Cough Syrup Market Analysis and Forecast, 2020-2021 & Forecast to 2026 with Germany Dominating - ResearchAndMarkets.com

Thursday, May 20, 2021 - 4:59pm

b'The "Europe Cough Syrup Market By Product, By Age Group, By Distribution Channel, By Country, Growth Potential, Industry Analysis Report and Forecast, 2020 - 2026" report has been added to ResearchAndMarkets.com\'s offering.\nThe Germany market dominated the Europe Pediatric Market by Country in 2019, growing at a CAGR of 5.7 % during the forecast period.

Key Points: 
  • b'The "Europe Cough Syrup Market By Product, By Age Group, By Distribution Channel, By Country, Growth Potential, Industry Analysis Report and Forecast, 2020 - 2026" report has been added to ResearchAndMarkets.com\'s offering.\nThe Germany market dominated the Europe Pediatric Market by Country in 2019, growing at a CAGR of 5.7 % during the forecast period.
  • In addition, the ever-growing enhancements in products are projected to provide new growth prospects for the cough syrup market.\nThe increasing cases of respiratory issues are providing lucrative opportunities for the cough syrup market.
  • However, the misuse of cough syrup coupled with the strict rules & regulations by the government will restrict the market growth.
  • On the other hand, the high market potential of the developing regions will garner more growth opportunities for the cough syrup market growth.\nThe Retail Pharmacy market dominated the Spain Cough Syrup Market by Distribution Channel in 2019, thereby, achieving a market value of $85.9 million by 2026.

VistaGen’s PH10 Nasal Spray Demonstrates Different Mechanism of Action from Benzodiazepines in Preclinical Study

Thursday, March 11, 2021 - 1:30pm

Using in vitro patch clamp electrophysiology, PH10 had no agonist or antagonist effects on GABA receptors.

Key Points: 
  • Using in vitro patch clamp electrophysiology, PH10 had no agonist or antagonist effects on GABA receptors.
  • In September 2020, the U.S. Food and Drug Administration (FDA) released a Drug Safety Communication (DSC) detailing the risks associated with use of benzodiazepines.
  • PH10 is a new generation antidepressant with a mechanism of action that is designed to be fundamentally different from all current FDA-approved antidepressants.
  • PH10 is a Phase 2 investigational pherine nasal spray designed to have rapid-onset effects and therapeutic potential in several neuropsychiatric indications involving depression.

FDA accepts the new drug application for review of Idorsia’s daridorexant for the treatment of adult patients with insomnia

Wednesday, March 10, 2021 - 6:00am

The incidence of somnolence was low and did not increase with daridorexant 50 mg compared to placebo.

Key Points: 
  • The incidence of somnolence was low and did not increase with daridorexant 50 mg compared to placebo.
  • Patients reported no next-morning sleepiness compared to placebo as assessed by the morning visual analogue scale (VAS).
  • In April and July of 2020, Idorsia reported positive results in each of the two pivotal Phase 3 studies of daridorexant in patients with insomnia.
  • Daridorexant is a dual orexin receptor antagonist (DORA) designed and developed for the treatment of insomnia.

High Prescription of Psychoactive Class of Medicines for Mental Health Conditions spurs Growth in Benzodiazepine Drugs Market, Market Projected to touch Valuation of US$ 2.617 billion by 2026, TMR

Thursday, March 4, 2021 - 1:30pm

Such extensive use of the drug is anticipated to fuel growth of the global benzodiazepine drugs market over the analysis timeline, from 2018 to 2026.

Key Points: 
  • Such extensive use of the drug is anticipated to fuel growth of the global benzodiazepine drugs market over the analysis timeline, from 2018 to 2026.
  • In 2017, the global benzodiazepine drugs market was estimated to be worth around US $ 2055 Mn.
  • The market is projected to clock a growth rate of 2.7 % CAGR over the assessment tenure, from 2018 to 2026.
  • The global benzodiazepine drugs market is being driven by an increase in the prevalence of anxiety and seizures.

High Prescription of Psychoactive Class of Medicines for Mental Health Conditions spurs Growth in Benzodiazepine Drugs Market, Market Projected to touch Valuation of US$ 2.617 billion by 2026, TMR

Thursday, March 4, 2021 - 1:30pm

Such extensive use of the drug is anticipated to fuel growth of the global benzodiazepine drugs market over the analysis timeline, from 2018 to 2026.

Key Points: 
  • Such extensive use of the drug is anticipated to fuel growth of the global benzodiazepine drugs market over the analysis timeline, from 2018 to 2026.
  • In 2017, the global benzodiazepine drugs market was estimated to be worth around US $ 2055 Mn.
  • The market is projected to clock a growth rate of 2.7 % CAGR over the assessment tenure, from 2018 to 2026.
  • The global benzodiazepine drugs market is being driven by an increase in the prevalence of anxiety and seizures.

Addex GABAB Positive Allosteric Modulator Demonstrates Promise in Alcohol Use Disorder

Tuesday, February 16, 2021 - 6:00am

ADX71441 potently decreased binge-like drinking, reduced relapse-like drinking, and dose-dependently reduced alcohol self-administration as well as decreasing motivation to consume alcohol.

Key Points: 
  • ADX71441 potently decreased binge-like drinking, reduced relapse-like drinking, and dose-dependently reduced alcohol self-administration as well as decreasing motivation to consume alcohol.
  • Augier E. (2021) Recent Advances in the Potential of Positive Allosteric Modulators of the GABAB Receptor to Treat Alcohol Use Disorder.
  • (2014) Reduction of excessive alcohol drinking by a novel GABAB receptor positive allosteric modulator ADX71441 in mice.
  • (2017) The GABAB positive allosteric modulator ADX71441 attenuates alcohol self-administration and relapse to alcohol seeking in rats.

Washington Poison Center warns parents of continued dangers with the Benadryl™ Challenge

Monday, November 23, 2020 - 6:01pm

Diphenhydramine is an antihistamine commonly found in over-the-counter sleep aids, cough and cold medications, and allergy medicationsmost notably the brand name Benadryl.

Key Points: 
  • Diphenhydramine is an antihistamine commonly found in over-the-counter sleep aids, cough and cold medications, and allergy medicationsmost notably the brand name Benadryl.
  • It is typically stored in an unsecured or unlocked cabinet, and bulk quantities are available for purchase.
  • WA Poison Center Cases of intentional self-harm or suicidal intent in adolescents ages 13-17 has increased 5% since 2019, and cases of abuse have increased 34%.
  • For questions or emergencies involving diphenhydramine or other potentially harmful substances, call the Washington Poison Center (1-800-222-1222).

ESPAD Report 2019 — Results from the European School Survey Project on Alcohol and Other Drugs

Thursday, November 12, 2020 - 4:05pm

This report presents the results of the seventh ESPAD data-collection wave, conducted in 35 countries during the spring and autumn of 2019.

Key Points: 
  • This report presents the results of the seventh ESPAD data-collection wave, conducted in 35 countries during the spring and autumn of 2019.
  • It paints a comprehensive picture of the present situation among 1516-year-old school students as regards the use of cigarettes, alcohol, illicit drugs, inhalants, new psychoactive substances and pharmaceuticals, as well as providing insights into gambling, social media use and gaming.
  • The report offers an overview of trends for the period 1995-2019.