Journal of Internal Medicine

COVID-19’s impact on the vagus nerve, inflammatory reflex & long COVID: Feinstein Institutes & Karolinska Institutet study outlines potential therapies

Retrieved on: 
Wednesday, November 29, 2023
Health, Medical Devices, Infectious Diseases, COVID-19, Research, Science, Biotechnology, Karolinska Institute, DRS, Cytokine, Biomedical engineering, Interface (computing), Brain, Journal of Internal Medicine, Inflammatory Bowel Diseases, Disease, Homeostasis, Patient, Multimedia, Journal, Pelvic floor dysfunction, Pulmonary hypertension, Rheumatoid arthritis, Nervous system, Heart rate, Arthritis, Internal medicine, JIM, Neuroscience, Medical research, Molecular medicine, Paralysis, Periodic breathing, Credit, Cancer, Acetylcholine, Famotidine, VNS, Doctor of Philosophy, Sensation, SARS-CoV-2, Diabetes, Outline, Inflammation, Vagus nerve, HMGB1, Pharmaceutical industry, MD

View the full release here: https://www.businesswire.com/news/home/20231129335345/en/

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20231129335345/en/
    Dr. Kevin J. Tracey co-authored a new paper on the relationship between SARS-CoV-2 and the vagus nerve.
  • They also discussed potential therapies, particularly to reduce the progression of COVID-19 in infected patients as well as long COVID-19 treatment options.
  • “Studying the connection between COVID-19 and the vagus nerve is an important research avenue that needs further study,” said Dr. Andersson.
  • At the Feinstein Institutes, medical researchers use modern technology to develop new device-based therapies to treat disease and injury.

Guilt-Free Peanut Pleasures

Retrieved on: 
Tuesday, June 27, 2023
Wolk, Blood pressure, Pinterest, Consumer, Mineral, PMID, Nutrition, Depression, Lethargy, Food industry, Human services, Magnesium, Chocolate, United States Department of Health and Human Services, Stroke, Ice cream, Cohort (statistics), Vitamin E, Human, PubMed Central, International Journal of Obesity, Cheese, Research, Journal of Neurology, Neurosurgery, and Psychiatry, Inflammation, Meta-analysis, Dementia, Multimedia, Vitamin, Crave, Niacin, Metabolic syndrome, Canadian International Council, Risk, Randomized controlled trial, Immune system, Johan van Scheepen, Coffee, PubMed, Journal of Internal Medicine, Magic: The Gathering core sets, 1993–2007, United States Department of Agriculture, RDA, Memory, Alzheimer's disease, Skin, Fast food, Dietary supplement, Vegetable oil, Flour, Obesity

ALBANY, Ga. , June 27, 2023 /PRNewswire/ -- A summer indulgence that's guilt-free and packed with nutrition is possible. It all starts with a base of peanut butter or peanuts since just one serving of this mighty superfood delivers protein, fiber, healthy fats and 19 vitamins and minerals.

Key Points: 
  • In a food processor, blend together a 24-ounce container of full-fat cottage cheese, ½ cup peanut butter and ¼ cup plus two tablespoons maple syrup until smooth.
  • Stir in four chopped peanut butter cups and three tablespoons chopped peanuts.
  • Based in Albany, Ga., The Peanut Institute is a non-profit organization supporting nutrition research and developing educational programs to encourage healthful lifestyles that include peanuts and peanut products.
  • Consumption of peanut products improves memory and stress response in healthy adults from the ARISTOTLE study: A 6-month randomized controlled trial.

ABIONYX Pharma Receives FDA Orphan Drug Designation (ODD) for CER-001 for the Treatment of LCAT Deficiency Presenting as Kidney Dysfunction and/or Ophthalmologic Disease

Retrieved on: 
Tuesday, March 29, 2022
FDA, Health, Clinical Trials, Pharmaceutical, Optical, Biotechnology, Journal, Reverse cholesterol transport, Internal medicine, Plasma, RCT, Dialysis, Degenerative disease, Opacity (optics), Kidney, ODD, Research, Journal of Internal Medicine, Prognosis, Kidney disease, Medicine, CEO, Health, Food, Codocyte, LPX, Sepsis, Corneal opacity, COVID-19, Regulation of food and dietary supplements by the U.S. Food and Drug Administration, HDL, EMA, IgG4-related ophthalmic disease, FDA, Annals of Internal Medicine, Patient, Disease, Pharmaceutical industry, LCAT, THE BIO-HDL CER-001, ABIONYX PHARMA

The designation covers both partial LCAT deficiency, presenting as Fisheye Disease, and complete LCAT deficiency presenting with renal symptoms and corneal opacities.

Key Points: 
  • The designation covers both partial LCAT deficiency, presenting as Fisheye Disease, and complete LCAT deficiency presenting with renal symptoms and corneal opacities.
  • Progression of LCAT deficiency, for which there is no approved treatment, can ultimately lead to renal failure requiring dialysis or kidney transplant, and/or to complete corneal opacification requiring transplant.
  • The European Medicines Administration (EMA) granted ODD status to CER-001 for the treatment of LCATdeficiency in July 2021.
  • Positive clinical results from CER-001 in LCAT disease have previously been published.

New treatment for severe corneal inflammation from DED now listed on PBS

Retrieved on: 
Thursday, September 30, 2021
Narrative, News, Medical Affairs Bureau, TFOS, DED, PBS, Man, Duane syndrome, Optometry, Vaccine, International Regional Science Review, Diagnosis, Food, School, Patient, CSL, Inflammation, Health, S, Journal of Internal Medicine, Keratitis, TGA, Adult, S4, Matilde Leonardi, Classification, Professional services, Immune system, The National Interest, Itchy, Barabino, Current, Woman, Disease, Glass, Impact, Ophthalmology, COVID-19, Pharmaceutical Benefits Scheme, Safety, UNSW, Screen time, Time, George, Eye, Cornea, Pharmaceutical industry, Telescopic sight, Animal, Phosphorus, Health insurance, Medical device

(8,9)

Key Points: 
  • (8,9)
    MELBOURNE, Oct 1, 2021 - (ACN Newswire) - Today, adults living with severe corneal inflammation from DED (dry eye disease) gain access to a new treatment on the PBS.
  • Ikervis(R), Australia's first PBS listed disease-modifying ciclosporin eye drop treatment for severe keratitis in adults with DED, is now available (October 1, 2021).
  • "Artificial tears aim to provide symptom relief for DED, but don't address the underlying cause of severe corneal inflammation.
  • Executive Chair of The B Team Australasia, Lynette has spent the past 16 years living with severe corneal inflammation from DED.

DGAP-News: New data on innovative biomarkers used to guide the clinical management of septic patients

Retrieved on: 
Tuesday, August 31, 2021
Nexus, Acute kidney injury, Bed, Dipeptidyl peptidase-4 inhibitor, International Symposium on Endovascular Therapy, Heart, Blood, Glomerular filtration rate, Hennigsdorf, Nursing, Diagnosis, Journal of Internal Medicine, Emergency medicine, DPP3, IVD, Biomarker, Research, Endothelium, Intensive care medicine, Teaching hospital, Disease, Health, CA, Hollinger, Intermediate Care Facilities for Individuals with Mental Retardation, Clinic, Inflammation, University Hospital (Newark, New Jersey), ICU, Kidney, Education, Septic shock, Patient, High-dependency unit, Septic, Critical care, Adrenomedullin, Hypotension, Nephron, Pharmaceutical industry, Medical imaging, Hospital, Wood drying

Endothelial and kidney dysfunction are common complications in septic patients leading to organ failure and unfavorable outcomes.

Key Points: 
  • Endothelial and kidney dysfunction are common complications in septic patients leading to organ failure and unfavorable outcomes.
  • The organ-specific biomarkers bio-ADM and penKid are used in clinical routine for monitoring the endothelium and respectively kidney function in intensive care units.
  • The use of biomarkers that can facilitate a faster and better diagnosis and monitoring of sepsis progression allows clinicians to provide the best available treatment.
  • I am excited to share with the critical care community the latest insights on improving septic patients' management with the help of innovative biomarkers."