International development

Kymera Therapeutics Announces First Patient Dosed in Phase 2 Atopic Dermatitis Clinical Trial of KT-474 (SAR444656), a First-in-Class, Investigational IRAK4 Degrader, Generating a $15 Million Payment from Sanofi

Retrieved on: 
Thursday, December 7, 2023
Sanofi, HS, Inflammation, Disease, Doctor of Philosophy, Therapy, Oral medicine, International development, TPD, Patient, Safety, Pharmaceutical industry

WATERTOWN, Mass., Dec. 07, 2023 (GLOBE NEWSWIRE) -- Kymera Therapeutics, Inc. (NASDAQ: KYMR), a clinical-stage biopharmaceutical company advancing a new class of small molecule medicines using targeted protein degradation (TPD), today announced that the first patient has been dosed in the randomized Phase 2 clinical trial (ADVANTA) evaluating KT-474 (SAR444656) in AD, generating a $15 million milestone payment under its collaboration with Sanofi. The Phase 2 study will evaluate the efficacy and safety of KT-474, a first-in-class, investigational IRAK4 degrader, compared with placebo in adult patients with moderate to severe AD. Sanofi is conducting Phase 2 KT-474 studies in both AD and HS, and dosed the first HS patient in October 2023, which generated a $40 million milestone payment under the terms of the collaboration. Study completion dates for both trials are projected in the first quarter of 2025.

Key Points: 
  • The Phase 2 study will evaluate the efficacy and safety of KT-474, a first-in-class, investigational IRAK4 degrader, compared with placebo in adult patients with moderate to severe AD.
  • Sanofi is conducting Phase 2 KT-474 studies in both AD and HS, and dosed the first HS patient in October 2023 , which generated a $40 million milestone payment under the terms of the collaboration.
  • Study completion dates for both trials are projected in the first quarter of 2025.
  • “We are pleased to be working with Kymera to explore the potential of IRAK4 degradation to treat a variety of inflammatory conditions, including in our recently initiated Phase 2 AD and HS trials.”

Global Leaders Unite at the Uae Pavilion at Cop28 to Discuss Powerful Partnerships for Sustainable Food Systems

Retrieved on: 
Sunday, December 3, 2023
Science, Melinda French Gates, Environment, International development, Climate, United, Climate change, Nature, World Bank, COP26, Sustainable development, AIM, G7, University, NEP, Organization, Food security, Partnership, Jeff Bezos, CGIAR, Bill, COP28, Jameel, Thermal expansion, Farmer, Sustainable agriculture, Renewable energy

The three-part lightning panel session emphasized the significance of strategic collaborations, aligning with the implementation of the Emirates Declaration on Sustainable Agriculture, Resilient Food Systems and Climate Action, as well as the broader COP28 Food Systems and Agriculture Agenda.

Key Points: 
  • The three-part lightning panel session emphasized the significance of strategic collaborations, aligning with the implementation of the Emirates Declaration on Sustainable Agriculture, Resilient Food Systems and Climate Action, as well as the broader COP28 Food Systems and Agriculture Agenda.
  • Moderated by Kristofer Hamel, Head of the COP28 Food Systems Team, the dialogue showcased three pivotal partnership platforms of Consultative Group on International Agricultural Research (CGIAR), AIM for Climate and Food Systems Technical Cooperation Collaborative, with each playing a crucial role in advancing the sustainable goals of COP28.
  • Juergen Voegele, Ph.D, Vice President for Sustainable Development, World Bank, hailed the talk as an historic moment, fulfilling last year's promise to transform global food systems.
  • He called for support to accelerate these vital changes, underscoring the critical role of partnerships in achieving the ambitious goals set forth by COP28, with commitments from global leaders towards a sustainable future.

Dickey’s Barbecue Pit Continues Smokin’ Expansion in Toronto

Retrieved on: 
Wednesday, November 29, 2023
Greater Toronto Area, Family, Hospitality, Partnership, People (magazine), Restaurant, Woman, The Wall Street Journal, USA Today, DRB, American City Business Journals, Franchise Times, International development, The Dallas Morning News, Fox News, BBQ, News, Baking

Dallas, Nov. 29, 2023 (GLOBE NEWSWIRE) -- Dickey’s Barbecue Pit will continue to expand their fast-growing Canadian development alongside one of their own.

Key Points: 
  • Dallas, Nov. 29, 2023 (GLOBE NEWSWIRE) -- Dickey’s Barbecue Pit will continue to expand their fast-growing Canadian development alongside one of their own.
  • Dickey’s Barbecue Restaurants, Inc ., the world’s largest barbecue concept, was founded in 1941 by the Dickey family.
  • For the past 82 years, Dickey’s Barbecue Pit has served millions of guests in 41 states Legit.
  • Barbecue.™ At Dickey’s, all our barbecued meats are smoked onsite in a hickory wood burning pit.

Dupixent® (dupilumab) Significantly Reduced COPD Exacerbations in Second Positive Phase 3 Trial, Accelerating FDA Submission and Confirming Potential to Become First Approved Biologic for This Serious Disease

Retrieved on: 
Monday, November 27, 2023
Patient, Regeneron Pharmaceuticals, Food, Smoker, Aes, Breakthrough therapy, Death, Upper respiratory tract infection, Diarrhea, FDA, Hypertension, Headache, Common, Inflammation, COVID-19, European Medicines Agency, Doctor of Philosophy, International development, Back pain, Phenotype, Safety, History, Pharmaceutical industry

TARRYTOWN, N.Y. and PARIS, Nov. 27, 2023 (GLOBE NEWSWIRE) -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announced that the second Dupixent® (dupilumab) investigational Phase 3 chronic obstructive pulmonary disease (COPD) trial (NOTUS) showed that Dupixent significantly reduced (34%) exacerbations, confirming positive results from the landmark Phase 3 BOREAS trial. The NOTUS trial also confirmed that treatment with Dupixent led to rapid and significant improvements in lung function by 12 weeks and were sustained at 52 weeks.

Key Points: 
  • “These results demonstrate the important role of type 2 inflammation in yet another chronic and debilitating disease, and the ability of Dupixent to address this inflammation.
  • Patients receiving Dupixent compared to placebo experienced:
    34% reduction in moderate or severe acute COPD exacerbations over 52 weeks (p=0.0002), the primary endpoint.
  • BOREAS results showed:
    30% reduction in moderate or severe acute COPD exacerbations over 52 weeks (p=0.0005), the primary endpoint.
  • The safety and efficacy of Dupixent in COPD are currently under clinical investigation and have not been evaluated by any regulatory authority.

Transak Joins Forces with Blockchain Game Alliance to Revolutionize Web3 Gaming Onboarding

Retrieved on: 
Monday, November 27, 2023
Blockchain, Animoca Brands, Ecosystem, Family, HTTPS, Partnership, Ubisoft, Financial Crimes Enforcement Network, FCA, TSL, SSL, Internet, International development, Growth, BGA, Environment, Cryptocurrency

Miami, USA, Nov. 27, 2023 (GLOBE NEWSWIRE) --  Transak, a Web3 onboarding solutions company backed by Animoca Brands, is excited to announce its new membership with the Blockchain Game Alliance (BGA). BGA is an organization focused on promoting the adoption of blockchain within the gaming industry. An integral piece of this puzzle is effortless entry into the blockchain gaming ecosystem.

Key Points: 
  • Miami, USA, Nov. 27, 2023 (GLOBE NEWSWIRE) -- Transak , a Web3 onboarding solutions company backed by Animoca Brands, is excited to announce its new membership with the Blockchain Game Alliance (BGA).
  • Transak is at the forefront of addressing this challenge, simplifying the onboarding process for gamers with its user-friendly platform.
  • In line with its commitment to gaming, Transak recently introduced its NFT Checkout , a self-serve fiat-to-NFT product.
  • With Transak and BGA coming together to abstract away the complexities that typically entail Web3 game onboarding, users who may have been daunted by the technical aspects of Web3 gaming can now engage more easily, fostering a wider adoption and growth of the blockchain gaming ecosystem.

Mangata Networks Forges Strategic Collaboration with Microsoft to Pioneer AI-Enabled Edge Cloud Connectivity via Satellite

Retrieved on: 
Friday, December 22, 2023
Cloud, Gentlemen's agreement, ISV, Microsoft, MEO, United, USAID, HEO, Partnership, SLA, SCADA, Telecommunications, Microsoft Azure, Digital divide, International development, Innovation, Internet of things, Internet, Knowledge, Engineering, Cloud computing, Data management, Organization, Video game

PHOENIX, Dec. 22, 2023 /PRNewswire/ -- Mangata Networks, a global company offering satellite-enabled connectivity & intelligent edge computing solutions, has signed a partnership with Microsoft aimed at developing an AI-enabled edge cloud product connected via satellite. This partnership represents a long-term commitment between Mangata Networks and Microsoft, marking the beginning of a sustained collaborative journey aimed at continuously advancing cloud technology through innovative satellite connectivity.

Key Points: 
  • PHOENIX, Dec. 22, 2023 /PRNewswire/ -- Mangata Networks, a global company offering satellite-enabled connectivity & intelligent edge computing solutions, has signed a partnership with Microsoft aimed at developing an AI-enabled edge cloud product connected via satellite.
  • This partnership represents a long-term commitment between Mangata Networks and Microsoft, marking the beginning of a sustained collaborative journey aimed at continuously advancing cloud technology through innovative satellite connectivity.
  • "We are thrilled to develop this transformative product in strategic collaboration with Microsoft, further enriching the Microsoft commercial marketplace ecosystem.
  • "In collaboration with Mangata, we look forward to delivering an end-to-end Cloud and Edge platform to enterprise and government customers.

Mangata Networks Forges Strategic Collaboration with Microsoft to Pioneer AI-Enabled Edge Cloud Connectivity via Satellite

Retrieved on: 
Friday, December 22, 2023
Cloud, Gentlemen's agreement, ISV, Microsoft, MEO, United, USAID, HEO, Partnership, SLA, SCADA, Telecommunications, Microsoft Azure, Digital divide, International development, Innovation, Internet of things, Internet, Knowledge, Engineering, Cloud computing, Data management, Organization, Video game

PHOENIX, Dec. 22, 2023 /PRNewswire/ -- Mangata Networks, a global company offering satellite-enabled connectivity & intelligent edge computing solutions, has signed a partnership with Microsoft aimed at developing an AI-enabled edge cloud product connected via satellite. This partnership represents a long-term commitment between Mangata Networks and Microsoft, marking the beginning of a sustained collaborative journey aimed at continuously advancing cloud technology through innovative satellite connectivity.

Key Points: 
  • PHOENIX, Dec. 22, 2023 /PRNewswire/ -- Mangata Networks, a global company offering satellite-enabled connectivity & intelligent edge computing solutions, has signed a partnership with Microsoft aimed at developing an AI-enabled edge cloud product connected via satellite.
  • This partnership represents a long-term commitment between Mangata Networks and Microsoft, marking the beginning of a sustained collaborative journey aimed at continuously advancing cloud technology through innovative satellite connectivity.
  • "We are thrilled to develop this transformative product in strategic collaboration with Microsoft, further enriching the Microsoft commercial marketplace ecosystem.
  • "In collaboration with Mangata, we look forward to delivering an end-to-end Cloud and Edge platform to enterprise and government customers.

Stanley Tucci Takes on New Adventures in Italy With National Geographic

Retrieved on: 
Thursday, December 14, 2023
Retail, Other Travel, Entertainment, Destinations, Travel, Consumer, Restaurant, Bar, General Entertainment, Celebrity, Lifestyle, Vacation, Wine & Spirits, TV and Radio, Food, Beverage, Politics, BBC Studios, Individual, History, Geology, Multimedia, HEART, Culture, Farmer, EVP, Geography, BBC, Partnership, Trentino-Alto Adige/Südtirol, International development, National Geographic, Knowledge, Film industry, Tucci

Today, National Geographic announced the greenlight of TUCCI – THE HEART OF ITALY (working title).

Key Points: 
  • Today, National Geographic announced the greenlight of TUCCI – THE HEART OF ITALY (working title).
  • View the full release here: https://www.businesswire.com/news/home/20231214735618/en/
    National Geographic announced the greenlight of TUCCI – THE HEART OF ITALY (working title).
  • “National Geographic is all about adventure and exploration, and I am honored to take viewers once again to explore Italy through the lens of food,” said Tucci.
  • “National Geographic is the perfect home for Stanley to share his knowledge and passion for Italy’s people, food and culture,” said Tom McDonald, EVP of Global Factual and Unscripted, National Geographic.

Tyler Technologies Announces Growing Adoption of Workforce Case Management Suite for Federal Government

Retrieved on: 
Tuesday, December 5, 2023
Data Management, Technology, Professional Services, White House, Federal Government, State, Local, Business, Other Technology, Software, Other Professional Services, Public Policy, Government, Human Resources, National Guard Bureau, Executive order, NYSE, TYL, MEO, EEO, Annual report, Equal Employment Opportunity Commission, National archives, Reasonable accommodation, Civil and political rights, Case management, Patent, DEI, International development, Property management, Cryptocurrency, AmeriCorps

Tyler Technologies, Inc. (NYSE: TYL) announced the growing selection and implementation of its Workforce Case Management suite among federal government agencies.

Key Points: 
  • Tyler Technologies, Inc. (NYSE: TYL) announced the growing selection and implementation of its Workforce Case Management suite among federal government agencies.
  • Federal agencies are continuing to ensure they have the systems in place to capture, manage, and report on complaints across the full workforce case management spectrum.
  • As the only vendor to offer a comprehensive suite of off-the-shelf Workforce Case Management Applications, Tyler has signed agreements with several additional federal agencies in the past year to respond to the growing focus on DEI and accessibility requirements within government.
  • Tyler has more than 20 years of experience managing federal EEO and related workforce case management grievance claims.

ReNew Successfully Commissions Its First Interstate Transmission Scheme (ISTS) Project Following Investment From Norfund and KLP

Retrieved on: 
Thursday, November 16, 2023
Sustainability, Alternative Energy, Energy, Environment, EBITDA, Climate Investment Funds, Safety, Investment, Collection, MVA, Government, Standard, Climate, Wind, AIS, Partnership, ISTS, CTU, KV, KLP, International development, RNW, ICRA, Electric power, Renewable energy, ReNew, Koppal, PGCIL, Gadag-Betageri

ReNew (“ReNew”, RNW, RNWWW: NASDAQ), India’s leading decarbonization solutions company, has commissioned its first interstate transmission project, the “Koppal Transmission Scheme”.

Key Points: 
  • ReNew (“ReNew”, RNW, RNWWW: NASDAQ), India’s leading decarbonization solutions company, has commissioned its first interstate transmission project, the “Koppal Transmission Scheme”.
  • Following the commissioning of the 1,500 MW Koppal Transmission Scheme, the remaining transmission for 3,500 MW is expected to be completed by June 2024.
  • Following the announcement, an agreement was signed yesterday on the second joint investment in the transmission sector with Norfund, the Norwegian Government’s Investment Fund for developing countries, and KLP, Norway’s largest pension company, through their joint company KNI India AS.
  • The investment by Norfund and KLP in ReNew’s transmission projects is in line with ReNew’s farm-down strategy, enabling ReNew to add further capacity.