Gene Mutation May Explain Brain Cell Plaque Buildup in Alzheimer's Disease
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Wednesday, November 30, 2022
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The buildup of such clumps, also called plaque, sets off an immune response that can kill brain cells and may lead to the dementia associated with Alzheimer's disease.
Key Points:
- The buildup of such clumps, also called plaque, sets off an immune response that can kill brain cells and may lead to the dementia associated with Alzheimer's disease.
- The new findings may offer a potential new target for therapies that directly affect the gene mutation, according to the study authors.
- Notably, this cluster is known to produce molecules that trigger inflammation in Parkinson's disease, Huntington's disease, and various forms of dementia.
- They compared these findings to previous research in humans with Alzheimer's disease, observing the same genetic changes in the gene cluster linked to plaque.