Where Computation and Experimentation Collide
Retrieved on:
Wednesday, September 7, 2022
Cardiovascular disease, Machine learning, University of California, San Francisco, Degenerative disease, RNA, Cancer, Rupture, UC, Research, Gene, Gladstone Institutes, Genetics, SAN, Boston Children's Hospital, Doctor of Philosophy, Time, Communication, Disease, Heart, Mouse, Tissue, Hope, MIT, Cardiomyopathy, Department, California Institute of Technology, Gene expression, Cell, Chromatin, Harvard University, Deep learning, MD, Map, Dana–Farber Cancer Institute, Biology, Architecture, Hospital, California Institute for Quantitative Biosciences, Aortic aneurysm, UCSF, Aorta, Clinical trial, Broad Institute, University, Eric Davidson, Life, IPS, Media contacts database, Patient, Coffee, Medical imaging, Pharmaceutical industry, Medicine, Vaccine, Surveying, William Ewart Gladstone, Technology, Pediatrics
SAN FRANCISCO, Sept. 6, 2022 /PRNewswire/ -- In order for our hearts to form correctly and keep us thriving, hundreds of genes must act together in complex networks. If part of a network malfunctions, cardiovascular disease may arise.
Key Points:
- Now, after 5 years as a resident in pediatric genetics at Boston Children's Hospital, Theodoris has returned to San Francisco.
- In addition to her new role at Gladstone, she is also joining UCSF as an assistant professor in the Department of Pediatrics.
- Drugs that treat disease by targeting individual dysfunctional genes already exist for many illnesses, especially different types of cancer.
- This union of computation and experimentation surfaced a promising drug candidate that successfully prevented calcific aortic valve disease in mice.