NORTH

Adlai Nortye Announces Completion of Patient Enrollment in Global Phase III Clinical Trial of Buparlisib (AN2025) in Combination with Paclitaxel for the Treatment of Recurrent or Metastatic HNSCC

Retrieved on: 
Friday, November 17, 2023

This clinical study evaluates buparlisib (AN2025), an oral pan-PI3K inhibitor, in combination with paclitaxel for the treatment of recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).

Key Points: 
  • This clinical study evaluates buparlisib (AN2025), an oral pan-PI3K inhibitor, in combination with paclitaxel for the treatment of recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).
  • This represents the first global multicenter phase III trial for HNSCC in the class of PI3K inhibitors.
  • "There is a high unmet medical need for patients with recurrent or metastatic HNSCC after anti-PD-1/anti-PD-L1 therapy.
  • As the trial is now fully enrolled, we eagerly look forward to the results which may change the paradigm of second-line treatment for HNSCC and provide a new treatment option for patients worldwide," said Lars Birgerson, President and Chief Medical Officer of Adlai Nortye Ltd.

CONTINUED SPARE CAPACITY AT GLOBAL SUPPLIERS WARNS OF MANUFACTURING SLUMP PERSISTING INTO 2024: GEP GLOBAL SUPPLY CHAIN VOLATILITY INDEX

Retrieved on: 
Thursday, December 14, 2023

"This persistent, month-after-month, excess vendor capacity means that the end to the global manufacturing recession is still some way off," explained Todd Bremer, vice president, consulting, GEP.

Key Points: 
  • "This persistent, month-after-month, excess vendor capacity means that the end to the global manufacturing recession is still some way off," explained Todd Bremer, vice president, consulting, GEP.
  • Continuing excess supplier capacity in Asia gives manufacturers greater leverage to drive down prices in 2024."
  • Capacity at Asia's suppliers went underutilized to one of the greatest degrees in the post-pandemic era, boding ill for the near-term outlook of global manufacturing.
  • The next release of the GEP Global Supply Chain Volatility Index will be 8 a.m.

CONTINUED SPARE CAPACITY AT GLOBAL SUPPLIERS WARNS OF MANUFACTURING SLUMP PERSISTING INTO 2024: GEP GLOBAL SUPPLY CHAIN VOLATILITY INDEX

Retrieved on: 
Thursday, December 14, 2023

"This persistent, month-after-month, excess vendor capacity means that the end to the global manufacturing recession is still some way off," explained Todd Bremer, vice president, consulting, GEP.

Key Points: 
  • "This persistent, month-after-month, excess vendor capacity means that the end to the global manufacturing recession is still some way off," explained Todd Bremer, vice president, consulting, GEP.
  • Continuing excess supplier capacity in Asia gives manufacturers greater leverage to drive down prices in 2024."
  • Capacity at Asia's suppliers went underutilized to one of the greatest degrees in the post-pandemic era, boding ill for the near-term outlook of global manufacturing.
  • The next release of the GEP Global Supply Chain Volatility Index will be 8 a.m.

The US Department of Energy and 6K Energy Execute Agreement for the $50M Grant for the PlusCAM Battery Material Production Plant in Jackson, TN

Retrieved on: 
Wednesday, December 13, 2023

NORTH ANDOVER, Mass., Dec. 13, 2023 /PRNewswire/ -- 6K Energy, a division of 6K and leader in the sustainable production of critical materials for lithium-ion batteries, today announced the execution of a $50M award with the US Department of Energy's (DOE's) Office of Manufacturing and Energy Supply Chains for its PlusCAM battery material production plant located in Jackson, TN. The $50M award will go toward the >$200M construction cost for the PlusCAM factory.

Key Points: 
  • PlusCAM will leverage the company's proprietary UniMeltÒ microwave plasma technology for cathode active material (CAM) production.
  • The PlusCAM facility will be the model for supplying battery material to major automotive OEMs and suppliers such as 6K investor Stellantis and EU auto manufacturers.
  • The UniMelt technology is already operating at full-scale production at 6K Energy's sister company, 6K Additive, producing metal powders for additive manufacturing.
  • The company has begun hiring in Jackson, TN, and expects to have approximately 230 employees when the factory is at full-scale capacity.

The US Department of Energy and 6K Energy Execute Agreement for the $50M Grant for the PlusCAM Battery Material Production Plant in Jackson, TN

Retrieved on: 
Wednesday, December 13, 2023

NORTH ANDOVER, Mass., Dec. 13, 2023 /PRNewswire/ -- 6K Energy, a division of 6K and leader in the sustainable production of critical materials for lithium-ion batteries, today announced the execution of a $50M award with the US Department of Energy's (DOE's) Office of Manufacturing and Energy Supply Chains for its PlusCAM battery material production plant located in Jackson, TN. The $50M award will go toward the >$200M construction cost for the PlusCAM factory.

Key Points: 
  • PlusCAM will leverage the company's proprietary UniMeltÒ microwave plasma technology for cathode active material (CAM) production.
  • The PlusCAM facility will be the model for supplying battery material to major automotive OEMs and suppliers such as 6K investor Stellantis and EU auto manufacturers.
  • The UniMelt technology is already operating at full-scale production at 6K Energy's sister company, 6K Additive, producing metal powders for additive manufacturing.
  • The company has begun hiring in Jackson, TN, and expects to have approximately 230 employees when the factory is at full-scale capacity.

Bright MLS November Housing Report: Mid-Atlantic Market Continues to Defy Expectations

Retrieved on: 
Tuesday, December 12, 2023

NORTH BETHESDA, Md., Dec. 12, 2023 /PRNewswire/ -- Even as mortgage rates hit a two-decade high in November, homebuyers remain active throughout the Mid-Atlantic region. The number of closed sales continued to track below last year's levels, with 15,970 total sales throughout the region, down 6.3% from November 2022. However, there were 15,964 new pending sales last month, which is down just 0.7% compared to a year ago.

Key Points: 
  • "Housing demand has remained strong this fall, despite higher rates," said Dr. Lisa Sturtevant, Bright MLS Chief Economist.
  • At the end of the month, there was a total of 32,522 active listings across the Bright MLS service area.
  • According to the Bright MLS T3 Home Demand Index (HDI), the Philadelphia metro market remains limited.
  • According to the Bright MLS T3 Home Demand Index (HDI), market conditions in the Washington, D.C. metro declined slightly month-over-month, from 58 in November to 56 in December, indicating limited market activity.

Gilead Sciences Partners with the ISPE Foundation to Provide Grants to 93 Students and Recent Graduates

Retrieved on: 
Thursday, December 7, 2023

NORTH BETHESDA, Md., Dec. 7, 2023 /PRNewswire-PRWeb/ -- The International Society for Pharmaceutical Engineering (ISPE), in partnership with the ISPE Foundation and through the generous support of Gilead Sciences, provided 93 students and recent graduates with grants to attend the 2023 ISPE Annual Meeting and Expo in Las Vegas, Nevada, USA. The grant recipients who attended the annual industry-focused conference hailed from 12 countries, 33 universities, and 31 companies.

Key Points: 
  • The ISPE Foundation, with support from like-minded organizations such as Gilead Sciences, champions programs that create opportunity, diversity, and success within the global pharmaceutical industry.
  • NORTH BETHESDA, Md., Dec. 7, 2023 /PRNewswire-PRWeb/ -- The International Society for Pharmaceutical Engineering (ISPE), in partnership with the ISPE Foundation and through the generous support of Gilead Sciences , provided 93 students and recent graduates with grants to attend the 2023 ISPE Annual Meeting and Expo in Las Vegas, Nevada, USA.
  • The grant recipients who attended the annual industry-focused conference hailed from 12 countries, 33 universities, and 31 companies.
  • Our membership is leading the way in shaping the future of the pharmaceutical industry," said Thomas Hartman, President and CEO of ISPE.

Gilbane Celebrates the Official Topping Out of Slate Upper School Project

Retrieved on: 
Wednesday, December 6, 2023

NORTH HAVEN, Conn., Dec. 6, 2023 /PRNewswire/ -- Local officials from the State of Connecticut joined the Slate School community and representatives from Patriquin Architects and Gilbane Building Company to celebrate the official topping out of the 25,000-SF Slate Upper School.

Key Points: 
  • The Upper School is a continuation of Slate Lower School, which Gilbane delivered in 2018.
  • NORTH HAVEN, Conn., Dec. 6, 2023 /PRNewswire/ -- Local officials from the State of Connecticut joined the Slate School community and representatives from Patriquin Architects and Gilbane Building Company to celebrate the official topping out of the 25,000-SF Slate Upper School.
  • "We're proud to reach this milestone in the construction of Slate's Upper School," said John Hawley, vice president and business unit leader for Gilbane in Connecticut.
  • We look forward to safely completing the project and the future impact the school will have on its students."

Mass-Vac, Inc. Introduces MV PosiTrap® Dry Scroll Pump Exhaust Traps that Capture Carbon From Degrading Tip Seals

Retrieved on: 
Tuesday, December 5, 2023

NORTH BILLERICA, Mass., Dec. 5, 2023 /PRNewswire-PRWeb/ -- Mass-Vac, Inc. has introduced a line of robust vacuum pump exhaust traps for use with dry scroll pumps to remove carbon soot which can damage recirculation systems.

Key Points: 
  • NORTH BILLERICA, Mass., Dec. 5, 2023 /PRNewswire-PRWeb/ -- Mass-Vac, Inc. has introduced a line of robust vacuum pump exhaust traps for use with dry scroll pumps to remove carbon soot which can damage recirculation systems.
  • MV PosiTrap® Vacuum Pump Exhaust Traps are made from 304 SS and feature 0.1 micron polypropylene filter media that capture carbon soot from dry scroll pump degrading tip seals.
  • MV PosiTrap® Vacuum Pump Exhaust Traps are made from 304 SS and feature 0.1 micron polypropylene filter media that capture carbon soot from dry scroll pump degrading tip seals.
  • MV PosiTrap® Vacuum Pump Exhaust Traps are priced from $390 to $890, depending upon configuration.

Curriculum Associates Expands Student-Focused AI Capabilities with Purchase of Speech Recognition Leader SoapBox Labs

Retrieved on: 
Wednesday, November 29, 2023

NORTH BILLERICA, Mass., Nov. 29, 2023 /PRNewswire/ -- Curriculum Associates, a leading education technology company, announced today that it has acquired SoapBox Labs, a global leader in voice AI, powering equity-driven learning experiences for students.

Key Points: 
  • NORTH BILLERICA, Mass., Nov. 29, 2023 /PRNewswire/ -- Curriculum Associates, a leading education technology company, announced today that it has acquired SoapBox Labs, a global leader in voice AI, powering equity-driven learning experiences for students.
  • "Curriculum Associates and SoapBox Labs share a commitment to improving student outcomes by expanding access to high-quality instructional materials and innovative technologies," said Rob Waldron, CEO of Curriculum Associates.
  • Curriculum Associates and SoapBox Labs also share a commitment to using AI technologies to power equity and inclusivity, accessibility, and data privacy in the classroom for educators and their students.
  • East Wind Advisors served as financial advisor to SoapBox Labs in this transaction.