British Columbia Children's Hospital

New Insights Revealed On Tissue-Dependent Roles of JAK Signaling in Inflammation

Retrieved on: 
Thursday, December 21, 2023

NEW YORK, Dec. 21, 2023 /PRNewswire-PRWeb/ -- Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues. Their findings suggest a more precise approach is required to potentially expand JAK inhibitor use to a wider range of allergy and inflammatory disorders. Details on the findings were published in the December 21, 2023, issue of the journal Cell (DOI: 10.1016/j.cell.2023.11.027).

Key Points: 
  • Their findings suggest a more precise approach is required to potentially expand JAK inhibitor use to a wider range of allergy and inflammatory disorders.
  • Current JAK inhibitors work well against inflammation in diseases like eczema, but the study suggests a need for a nuanced approach in modulating JAK activity for conditions like asthma.
  • The study showed that activated JAK1 signaling has tissue-specific effects, including an unexpected immunoregulatory role in lung sensory neurons, where it suppresses lung inflammation.
  • In the lung neurons of the mice, the JAK1 mutant protein reduced inflammation caused by exposure to mold by producing substances that suppress inflammation.

TELUS Health launches next-generation medical alert system to support aging in place across Canada

Retrieved on: 
Tuesday, November 7, 2023

“We want to empower older adults to navigate life’s changes with greater ease by leveraging thoughtful advancements in technology, resources and expertise,” said Dr. Keir Peterson, Chief Medical Officer, TELUS Health.

Key Points: 
  • “We want to empower older adults to navigate life’s changes with greater ease by leveraging thoughtful advancements in technology, resources and expertise,” said Dr. Keir Peterson, Chief Medical Officer, TELUS Health.
  • The longest battery life of any mobile medical alert device in Canada for continuous protection.
  • To ensure flexibility and easier access to the new TELUS Health Medical Alert Pendant for older adults, multiple pricing options are offered starting at $60 per month.
  • For more information, or to purchase the TELUS Health Medical Alert Pendant, customers can call: 1-833-323-3383 or visit: telushealth.com/MedicalAlertPendant .

Children and Megan Khang win at CPKC Women's Open; nearly $3.5 million raised for heart health in B.C.

Retrieved on: 
Monday, August 28, 2023

"On behalf of the entire CPKC family, I want to congratulate Megan Khang on her win!

Key Points: 
  • "On behalf of the entire CPKC family, I want to congratulate Megan Khang on her win!
  • Together, we raised the biggest amount ever during our sponsorship of this this event, this year all in support of children's heart health in B.C.
  • "CPKC is honored to continue making a lasting difference in communities across Canada through CPKC Has Heart, our community investment program supporting heart health initiatives," Creel added.
  • "Over the last decade as title sponsor of the CPKC Women's Open, through CPKC Has Heart we've raised nearly $20 million for children's heart health."

In B.C., Alberta and around the world, forcing drug users into treatment is a violent policy

Retrieved on: 
Saturday, May 27, 2023

Intervention without human rights goes by many names — involuntary institutionalization, compulsory drug treatment, “coerced care,” forced abstinence or a combination of all of those terms.

Key Points: 
  • Intervention without human rights goes by many names — involuntary institutionalization, compulsory drug treatment, “coerced care,” forced abstinence or a combination of all of those terms.
  • Involuntary treatment in the Global South has been labelled inhumane by rights-based organizations, including the United Nations Office on Drugs and Crime, UNAIDS and Human Rights Watch.
  • In Alberta, Danielle Smith’s UCP has also proposed apprehending those with, in her words, “severe drug addiction.”

Increased risk of overdose

    • The evidence shows that forced treatment leads to increased risk of death and deprives survivors of autonomy, while no positive benefits have been established.
    • From Mexico to Sweden, Vancouver and England, involuntary treatment has been found to increase risk of overdose and shows no significant impact on substance use patterns.

Lowered tolerance

    • These overdoses are trending away from being predominantly non-fatal to being deadly due to the toxicity of the supply.
    • People are being discharged into the same living conditions with lowered tolerance.

Settler colonial violence continues

    • But reports suggest it is occurring through misuse of the province’s Mental Health Act.
    • The B.C.
    • Involuntary psychiatric detentions among youth, however, are at an all-time high in the province.
    • As with most punitive and carceral policies in Canada, the province’s Mental Health Act is used disproportionately against Indigenous people in British Columbia, including children — a disturbing continuation of the violence against Indigenous children that Canada is founded upon.

Relying on involuntary treatment

    • Involuntary psychiatric hospitalizations under the B.C.
    • Mental Health Act for those older than 14 also increased to 23,531 from 14,195 from 2008 until 2018 in the province.
    • Relying on a system designed to criminalize drug use, while temporarily stabilizing people via involuntary mental health treatment, risks causing further harm, trauma and death.
    • Read more:
      As an Indigenous doctor, I see the legacy of residential schools and ongoing racism in today's health care

Moral panics

    • Expanding forced treatment in Canada and elsewhere stems from the same moral panics that drove earlier drug prohibition regimes imposed through colonial power.
    • Provinces should collaborate with municipalities and health boards to expand life-saving and life-affirming safe use sites, and all levels of government must urgently prioritize solutions to the housing crisis.

BC Children's Hospital Foundation chosen as charity partner of 2023 CP Women's Open

Retrieved on: 
Wednesday, February 1, 2023

CALGARY, AB, Feb. 1, 2023 /PRNewswire/ - February is Heart Month, and Canadian Pacific (CP) is proud to announce today that BC Children's Hospital Foundation has been chosen as the primary charity partner for the 2023 CP Women's Open, to be held Aug. 21-27, 2023, at the Shaughnessy Golf & Country Club in Vancouver.

Key Points: 
  • CALGARY, AB, Feb. 1, 2023 /PRNewswire/ - February is Heart Month, and Canadian Pacific (CP) is proud to announce today that BC Children's Hospital Foundation has been chosen as the primary charity partner for the 2023 CP Women's Open, to be held Aug. 21-27, 2023, at the Shaughnessy Golf & Country Club in Vancouver.
  • "The 2023 CPWO marks the third time BC Children's Hospital Foundation has been selected as the charity partner during CP's title sponsorship of this exceptional LPGA Tour event, helping raise more than $4 million so far.
  • This year's goal is to raise more than $2.5 million for BC Children's Hospital.
  • "Kids with heart conditions can be some of the sickest children in BC, and the Heart Centre at BC Children's Hospital is there to provide care for every one of them," said Malcolm Berry, President and CEO of BC Children's Hospital Foundation.

Mining for Miracles Eyes 2022 Completion of $3.385 Million Fundraising Goal to Establish Cellular and Regenerative Medicine Centre (CRMC) at BC Children’s Hospital

Retrieved on: 
Thursday, February 17, 2022

VANCOUVER, British Columbia, Feb. 16, 2022 (GLOBE NEWSWIRE) -- Mining for Miracles, the BC mining industrys long-standing fundraising campaign for BC Childrens Hospital Foundation, launched its 2022 campaign today with Premier John Horgan, in support of BC Childrens Hospitals Cellular and Regenerative Medicine Centre (CRMC), the first of its kind in Western Canada.

Key Points: 
  • VANCOUVER, British Columbia, Feb. 16, 2022 (GLOBE NEWSWIRE) -- Mining for Miracles, the BC mining industrys long-standing fundraising campaign for BC Childrens Hospital Foundation, launched its 2022 campaign today with Premier John Horgan, in support of BC Childrens Hospitals Cellular and Regenerative Medicine Centre (CRMC), the first of its kind in Western Canada.
  • In 2022, Mining for Miracles launches the final leg of their campaign to fulfill their commitment, made in 2020, to establish the CRMC, a $3.385 million initiative.
  • We receive incredible support for the annual Mining for Miracles campaign from the thousands of women and men who work in the mining industry.
  • BC Childrens has the clinical and scientific expertise to be leaders in pediatric cellular and regenerative medicine, but they require infrastructure and equipment to do this.