Aurora B kinase

Jacobio Receives IND Approval for Aurora A Inhibitor JAB-2485 from FDA

Retrieved on: 
Monday, January 17, 2022

BEIJING and SHANGHAI and BOSTON, Jan. 16, 2022 /PRNewswire/ -- Jacobio's self-developed global first-in-class drug Aurora A inhibitor JAB-2485 received IND (Investigational New Drug) from the FDA (Food and Drug Administration) in US.

Key Points: 
  • BEIJING and SHANGHAI and BOSTON, Jan. 16, 2022 /PRNewswire/ -- Jacobio's self-developed global first-in-class drug Aurora A inhibitor JAB-2485 received IND (Investigational New Drug) from the FDA (Food and Drug Administration) in US.
  • Jacobio plans to initiate a Phase I/IIa clinical trial in patients with advanced solid tumors in the US.
  • JAB-2485 can inhibit Aurora A activity at the cellular level, induce apoptosis and inhibit tumor growth.
  • Jacobio's self-developed JAB-2485 is the third Aurora A inhibitor enter into clinical stagein the United States.