Pudendal nerve

Amber Therapeutics announces positive preliminary results from its first-in-human investigation of Amber-UI, its new adaptive implanted pudendal neuromodulation system for urinary incontinence

Retrieved on: 
Tuesday, February 27, 2024
UI, Woman, University of Antwerp, Overactive bladder, Urinary incontinence, Hope, Amber, Society, Pudendal nerve, Safety, SUFU, Biomarker, Lifting, Therapy, Incontinence, Patient, Stress incontinence, EMG, Peripheral nervous system, Cough, Pharmaceutical industry

The study fulfilled its primary aim of demonstrating safety and feasibility of Amber’s new surgical procedure, validating a scalable approach to accurately implant two electrode leads on the pudendal nerve.

Key Points: 
  • The study fulfilled its primary aim of demonstrating safety and feasibility of Amber’s new surgical procedure, validating a scalable approach to accurately implant two electrode leads on the pudendal nerve.
  • Clinically significant improvements in symptom-related quality-of-life were observed in both mixed and refractory urge UI patients.
  • In patients with mixed UI, this was manifest as reductions in both stress and urge incontinence events.
  • The study also demonstrated the utility of patient-controlled adaptive algorithms using Amber-UI’s integrated sensors.

Bicycle Saddle Brand HUAN Designs Safer Riding Saddles

Retrieved on: 
Tuesday, October 24, 2023
Online Retail, Retail, Sports, Manufacturing, Other Manufacturing, Biking, Cycling, Male, Environment, Health, Urethane, Weather, Pain, Pudendal nerve, Ventilation, Bookbinding

HUAN , a bicycle saddle brand, has developed two types of HUAN PPS4 prostate protection saddles to make riding safer and more comfortable.

Key Points: 
  • HUAN , a bicycle saddle brand, has developed two types of HUAN PPS4 prostate protection saddles to make riding safer and more comfortable.
  • The HUAN PPS4 Flat saddle is designed for people with large hips or a heavier weight, while the HUAN PPS4 Volume saddle is for those with small hips or a lighter weight.
  • Both saddles feature an ergonomically designed pad under the hipbones to reduce pain, divided into two sections to keep the pudendal nerve from contacting the saddle and prevent saddle pain.
  • For more information about HUAN and HUAN PPS Bicycle Saddles, please visit its website: https://huanpps.com/en/
    View source version on businesswire.com: https://www.businesswire.com/news/home/20231024053317/en/

Amber Therapeutics announces successful first-in-human implants of Amber-UI: an intelligent, closed-loop bioelectrical therapy for urge and mixed urinary incontinence

Retrieved on: 
Tuesday, January 24, 2023
Safety, Therapy, Pudendal nerve, University, Incontinence, Overactive bladder, Amber, Human, Genta (company), Partnership, UKRI, University of Oxford, Trial of the century, Queen Mary University of London, Raeng Ngao, DBS, Oxford Sciences Enterprises, Stress incontinence, Lifting, Urinary incontinence, Patient, Woman, DSM-IV codes, Peripheral nervous system, University of Antwerp, Cough, UI, Medical imaging, Pharmaceutical industry, Medical device, Urology

To explore the clinical potential of Amber-UI, the Company initiated its ground-breaking AURA-2 (Augmenting Urinary Reflex Activity) first-in-human study in late 2022 (clinicaltrials.gov identifier: NCT05241379).

Key Points: 
  • To explore the clinical potential of Amber-UI, the Company initiated its ground-breaking AURA-2 (Augmenting Urinary Reflex Activity) first-in-human study in late 2022 (clinicaltrials.gov identifier: NCT05241379).
  • AURA-2 is designed to evaluate the safety and pilot efficacy of Amber-UI in 15 women.
  • Aidan Crawley, CEO of Amber commented: "Reaching this first-in-human milestone in under two years demonstrates our ability to rapidly prototype new bioelectrical therapy concepts.
  • With our Amber-UI adaptive therapy, we finally have the potential to control both forms of incontinence: relaxing the bladder to treat urge and closing the sphincter to treat stress incontinence."

Amber Therapeutics announces successful first-in-human implants of Amber-UI: an intelligent, closed-loop bioelectrical therapy for urge and mixed urinary incontinence

Retrieved on: 
Tuesday, January 24, 2023
Safety, Therapy, Pudendal nerve, University, Incontinence, Overactive bladder, Amber, Human, Genta (company), Partnership, UKRI, University of Oxford, Trial of the century, Queen Mary University of London, Raeng Ngao, DBS, Oxford Sciences Enterprises, Stress incontinence, Lifting, Urinary incontinence, Patient, Woman, DSM-IV codes, Peripheral nervous system, University of Antwerp, Cough, UI, Medical imaging, Pharmaceutical industry, Medical device, Urology

To explore the clinical potential of Amber-UI, the Company initiated its ground-breaking AURA-2 (Augmenting Urinary Reflex Activity) first-in-human study in late 2022 (clinicaltrials.gov identifier: NCT05241379).

Key Points: 
  • To explore the clinical potential of Amber-UI, the Company initiated its ground-breaking AURA-2 (Augmenting Urinary Reflex Activity) first-in-human study in late 2022 (clinicaltrials.gov identifier: NCT05241379).
  • AURA-2 is designed to evaluate the safety and pilot efficacy of Amber-UI in 15 women.
  • Aidan Crawley, CEO of Amber commented: "Reaching this first-in-human milestone in under two years demonstrates our ability to rapidly prototype new bioelectrical therapy concepts.
  • With our Amber-UI adaptive therapy, we finally have the potential to control both forms of incontinence: relaxing the bladder to treat urge and closing the sphincter to treat stress incontinence."

Inspired Spine: Self-Reported Female Orgasm Following Serial Sacroiliac Joint Injections

Retrieved on: 
Tuesday, November 30, 2021
Patient, SIJ, Sensation, Time, Sacroiliac joint, Hip, Arousal, Pudendal nerve, Injection, Pain, Back pain, Female, Orgasm, Spine, Life, Pathology, Pharmaceutical industry

BURNSVILLE, Minn., Nov. 30, 2021 /PRNewswire/ -- Inspired Spine has announced an unusual but interesting medical finding after a patient received a sacroiliac joint (SIJ) injection and experienced the longest orgasm of her life.IS researchers published a peer-reviewed case report examining the event: Self-Reported Female Orgasm Following Serial Sacroiliac Joint Injections https://pubmed.ncbi.nlm.nih.gov/34471582/ .

Key Points: 
  • BURNSVILLE, Minn., Nov. 30, 2021 /PRNewswire/ -- Inspired Spine has announced an unusual but interesting medical finding after a patient received a sacroiliac joint (SIJ) injection and experienced the longest orgasm of her life.IS researchers published a peer-reviewed case report examining the event: Self-Reported Female Orgasm Following Serial Sacroiliac Joint Injections https://pubmed.ncbi.nlm.nih.gov/34471582/ .
  • It is following each of her three diagnostic SIJ injections that an Inspired Spine patient reported experiencing an orgasm lasting almost 2 hours.
  • This strange phenomenon occurred after receiving all three of her SIJ injections at the Inspired Spine clinic in Burnsville, MN.
  • We are currently monitoring our patients for similar symptoms following SIJ injections, and speculate that it could occur more commonly than reported.