Hyperventilation

Taysha Gene Therapies Reports Full Year 2023 Financial Results and Provides Corporate and Clinical Updates

Retrieved on: 
Tuesday, March 19, 2024

Notably, she has vastly increased interest in social communication and activities at week 35 compared to earlier post-treatment assessments.

Key Points: 
  • Notably, she has vastly increased interest in social communication and activities at week 35 compared to earlier post-treatment assessments.
  • Dr. Schultz is a board-certified, licensed pediatric neurologist experienced in treating patients with Rett syndrome and leading gene therapy clinical trials.
  • She brings more than 17 years of clinical experience and will lead the Company’s clinical development, clinical operations, medical affairs and safety activities.
  • ET to review its financial and operating results and to provide corporate and clinical updates.

Taysha Gene Therapies Reports Third Quarter 2023 Financial Results and Provides Corporate and Clinical Updates

Retrieved on: 
Tuesday, November 14, 2023

Following treatment, both patients experienced improvement in key clinical domains impacting activities of daily living, including breathing dysrhythmia, autonomic function, socialization, and gross and fine motor skills.

Key Points: 
  • Following treatment, both patients experienced improvement in key clinical domains impacting activities of daily living, including breathing dysrhythmia, autonomic function, socialization, and gross and fine motor skills.
  • Additional information on available clinical data is available in the Company’s quarterly report on Form 10-Q for the quarter ended September 30, 2023, to be filed with the SEC.
  • Cash and cash equivalents: As of September 30, 2023, the Company had cash and cash equivalents of $164.3 million.
  • Taysha management will hold a conference call and webcast today at 4:30 pm ET to review its financial and operating results and to provide corporate and clinical updates.

Breathing through your nose when you exercise may make your runs easier

Retrieved on: 
Tuesday, September 26, 2023

But when we exercise, many of us become more aware of it than we normally are – sometimes thinking about every breath we take.

Key Points: 
  • But when we exercise, many of us become more aware of it than we normally are – sometimes thinking about every breath we take.
  • During low and moderate-intensity exercises (such as walking and cycling), the majority of us breathe in through our nose and out through our mouths.
  • But the more intense the exercise becomes, the more we tend to breathe entirely through our mouths.
  • But evidence shows the contrary – and that breathing through your nose may actually be a better technique to use during intense exercise (such as running).
  • A series of studies have shown that when exercising at different intensities, less oxygen is used when breathing through the nose compared to breathing through your mouth.
  • This means the heart is under no additional stress when breathing through your nose during exercise.

23andMe Releases New Report Revealing Genetic Likelihood of Experiencing Panic Attacks

Retrieved on: 
Wednesday, June 21, 2023

The Panic Attacks Report, powered by 23andMe Research, adds to the collection of reports in the 23andMe service that focus on mental health, including reports also powered by 23andMe Research on depression and anxiety .

Key Points: 
  • The Panic Attacks Report, powered by 23andMe Research, adds to the collection of reports in the 23andMe service that focus on mental health, including reports also powered by 23andMe Research on depression and anxiety .
  • In some cases, if panic attacks occur more frequently and continue over time, they may be diagnosed as panic disorder, a type of anxiety disorder where panic attacks happen frequently.
  • 23andMe’s Panic Attacks Report is powered by data from people who have consented to participate in 23andMe Research.
  • 23andMe’s genetic health report on panic attacks can provide customers with helpful information on their estimated genetic likelihood of being diagnosed with the condition, but it is not a substitute for clinical diagnosis and treatment.

Fewer swimming lessons and lifeguard shortages make swimming even riskier this summer

Retrieved on: 
Monday, May 15, 2023

Gaps in swimming lessons, lifeguard shortages and climate change may make water-based activities even riskier this summer.

Key Points: 
  • Gaps in swimming lessons, lifeguard shortages and climate change may make water-based activities even riskier this summer.
  • Swimming pool closures at the start of the COVID-19 pandemic led to millions of Canadians missing swimming lessons.
  • With facilities now open across Canada, parents are having great difficulty enrolling their children in the limited swimming lessons that are currently available.

Lessons and lifeguards

    • However, the evidence on the value of swimming lessons in drowning prevention is not particularly strong.
    • In fact, some researchers have asserted that lessons might give parents a false sense of security, resulting in them not closely supervising their children.
    • So while there is concern about the lack of swimming lessons available to Canadians, an underrated drowning risk is swimming in unsupervised areas.
    • In Canada, fewer than one per cent of drownings occur in areas supervised by swimming instructors or lifeguards.

Dangerous swimming

    • As supervised hours at beaches and swimming pools are scaled back due to staff shortages, and the climate heats up, more people may turn to swimming in new or unsupervised locations to cool off.
    • People swimming in unfamiliar areas may not be aware of hidden hazards, like drop-offs or rocks, or be unfamiliar with rip currents.
    • Cold water can also be a danger, even during heatwaves in the summer months.
    • Experts suggest that water below 21 C can be dangerous.
    • Audrey R. Giles receives funding from the Social Sciences and Humanities Research Council of Canada and Transport Canada's Boating Safety Contribution Program.

Getting too excited can stop men from orgasming – but there’s a solution

Retrieved on: 
Monday, May 15, 2023

Sex may seem like a straightforward activity but it actually involves a high degree of coordination between the brain and body parts.

Key Points: 
  • Sex may seem like a straightforward activity but it actually involves a high degree of coordination between the brain and body parts.
  • Recent data suggests that erectile dysfunction affects around one in five UK men, with the figure rising to 50% for the 40-70 age group.
  • With this data in mind, we set out to explore how we could mathematically model the essence of sexual response in men and improve the experience.

Practical insights

    • In our mathematical model, we wanted to capture interactions between physiological and psychological aspects of sexual response in men.
    • Our model focused on how the levels of physiological and psychological arousal (turn-on) change during sexual stimulation.
    • We combined data about physiological responses from the Masters-Johnson study with insights from five functional magnetic resonance imaging (fMRI) studies of people having sex from 2003 to 2011. fMRI measures the small changes in blood flow that occur with brain activity.

Getting over excited

    • The results of our model show that if a man becomes psychologically overly excited, either due to their initial level of psychological turn-on before, or during sex, this can be detrimental to their chances of achieving orgasm.
    • One explanation for this is that when someone is overly excited they are too focused on their sexual performance or achieving an orgasm.
    • This can cause anxiety, which is itself a state of psychological overstimulation.
    • The solution to this is to mentally switch-off and relax to allow your psychological arousal to decrease.

What next?

    • Women have a greater variety of sexual responses that can include single or multiple orgasms.
    • Recent data suggests that while heterosexual men achieve orgasm about 95% of the time, the equivalent figure for heterosexual women is a measly 65%.

Alba Tull Makes $500,000 Gift to the Rett Syndrome Research Trust

Retrieved on: 
Tuesday, February 7, 2023

TRUMBULL, Conn., Feb. 7, 2023 /PRNewswire-PRWeb/ -- Alba Tull has made a generous donation of $500,000 to the Rett Syndrome Research Trust (RSRT) for a clinical study to determine the ability of the Emerald biosensor to accurately measure Rett syndrome symptoms, a key factor necessary for assessing the efficacy of drugs and genetic medicines.

Key Points: 
  • Alba Tull has made a generous donation of $500,000 to the Rett Syndrome Research Trust (RSRT) for a clinical study to determine the ability of the Emerald biosensor to accurately measure Rett syndrome symptoms, a key factor necessary for assessing the efficacy of drugs and genetic medicines.
  • TRUMBULL, Conn., Feb. 7, 2023 /PRNewswire-PRWeb/ -- Alba Tull has made a generous donation of $500,000 to the Rett Syndrome Research Trust (RSRT) for a clinical study to determine the ability of the Emerald biosensor to accurately measure Rett syndrome symptoms, a key factor necessary for assessing the efficacy of drugs and genetic medicines.
  • The Emerald sensor has been used in drug development in Alzheimer's and Parkinson's; this generous gift allows for testing its efficacy in Rett syndrome.
  • "RSRT continues to set and drive Rett syndrome research, and this donation is a reflection of my confidence in their singular mission to cure Rett," said Tull.

Takeda’s QDENGA®▼ (Dengue Tetravalent Vaccine [Live, Attenuated]) Approved for Use in European Union

Retrieved on: 
Thursday, December 8, 2022

Guidance for use: QDENGA should be administered by subcutaneous injection preferably in the upper arm in the region of deltoid.

Key Points: 
  • Guidance for use: QDENGA should be administered by subcutaneous injection preferably in the upper arm in the region of deltoid.
  • Appropriate medical treatment and supervision must always be readily available in the event of a rare anaphylactic reaction following administration of the vaccine.
  • 2020;395:1423-1433.
    x Tricou, V. Efficacy and Safety of Takedas Tetravalent Dengue Vaccine Candidate (TAK-003) After 4.5 Years of Follow-Up.
  • December 2022.
    xiv Efficacy, Safety and Immunogenicity of Takedas Tetravalent Dengue Vaccine (TDV) in Healthy Children (TIDES).

Takeda’s QDENGA®▼ (Dengue Tetravalent Vaccine [Live, Attenuated]) Approved in Indonesia for Use Regardless of Prior Dengue Exposure

Retrieved on: 
Monday, August 22, 2022

QDENGA is the only dengue vaccine approved in Indonesia for use in individuals regardless of previous dengue exposure and without the need for pre-vaccination testing.1

Key Points: 
  • QDENGA is the only dengue vaccine approved in Indonesia for use in individuals regardless of previous dengue exposure and without the need for pre-vaccination testing.1
    Dengue can affect anyone living in or traveling to endemic areas - regardless of age, health and socio-economic circumstances, said Gary Dubin, president of Takedas Vaccine Business Unit.
  • The TIDES trial met its primary endpoint of overall vaccine efficacy (VE) against virologically-confirmed dengue (VCD) with 80.2% efficacy at 12-months follow-up.
  • 6 Tricou, V. Efficacy and Safety of Takedas Tetravalent Dengue Vaccine Candidate (TAK-003) After 4.5 Years of Follow-Up.
  • Efficacy of a tetravalent dengue vaccine in healthy children aged 4-16 years: a randomized, placebo controlled, phase 3 trial.

Asep Medical Holdings Inc. Announces Additional Listing to the OTCQB Venture Market in the U.S.

Retrieved on: 
Thursday, April 21, 2022

VANCOUVER, BC, April 21, 2022 /PRNewswire/ - Asep Medical Holdings Inc. ("Asep Inc." or the "Company") (CSE: ASEP) (OTCQB: SEPSF)is pleased to announce its recent successful listing on the OTCQB Venture Market in the US.

Key Points: 
  • VANCOUVER, BC, April 21, 2022 /PRNewswire/ - Asep Medical Holdings Inc. ("Asep Inc." or the "Company") (CSE: ASEP) (OTCQB: SEPSF)is pleased to announce its recent successful listing on the OTCQB Venture Market in the US.
  • Asep Inc. will officially commence trading on the OTCQB as of the market opening today.
  • The listing is expected to provide us with added liquidity and a diversified investor base in a large established public market.
  • ABOUT ASEP MEDICAL HOLDINGS INC.
    Asep Inc. is dedicated to addressing antibiotic failure by developing novel solutions for significant unmet medical needs.