Research Reveals Novel Insights into Transplant Rejection and New Drug Development Targets
CINCINNATI, June 28, 2023 /PRNewswire/ -- Imagine a day when a urine test could inform a doctor precisely why a kidney transplant patient was experiencing organ rejection and suggest the best medication for specifically addressing the problem.
- Findings suggests that multiple organ rejection events may actually be one, longer, smoldering rejection event.
- "Having a precision-medicine approach to treating organ rejection has the potential to markedly reduce the threat rejection poses to transplanted organs," Woodle says.
- However, once a kidney transplant recipient experiences acute rejection, many go on to lose their transplant and return to dialysis within 1-3 years.
- "Thanks to insights like these, we may be able to substantially reduce loss of transplanted organs to rejection, thereby freeing up donated organs for new transplant recipients."