Aminoacyl tRNA synthetases, class I

Ambys Medicines Presents New Data Further Validating its Novel Liver Cell Replacement Therapy Platform at the ASGCT Annual Meeting

Retrieved on: 
Wednesday, May 18, 2022

Ambyss proprietary platform enables the first and only development and manufacture of functional human hepatocytes, unlocking the full potential of hepatocyte replacement therapy.

Key Points: 
  • Ambyss proprietary platform enables the first and only development and manufacture of functional human hepatocytes, unlocking the full potential of hepatocyte replacement therapy.
  • "Our new data show that Ambys is capable at efficient genetic modification of primary human hepatocytes, unleashing a powerful combination of cell and gene therapy in hepatocytes, said Ron Park, M.D., Chief Executive Officer of Ambys Medicines.
  • "The universal hepatocyte data presented today coupled with the data on our hyperfunctional human hepatocyte program and in vivo bioreactor platform presented earlier this week further validate our breakthrough replacement cell therapy approach for severe liver diseases.
  • Ambys Medicines is focused on pioneering cell replacement therapies for patients with liver failure.

New buck/boost converter maintains industry's lowest IQ while integrating supercapacitor charging

Retrieved on: 
Wednesday, November 3, 2021

The TPS61094 buck/boost converter integrates a buck mode for supercapacitor charging while providing ultra-low IQ, enabling engineers to extend battery life by as much as 20% when compared to commonly used hybrid-layer capacitors (HLCs).

Key Points: 
  • The TPS61094 buck/boost converter integrates a buck mode for supercapacitor charging while providing ultra-low IQ, enabling engineers to extend battery life by as much as 20% when compared to commonly used hybrid-layer capacitors (HLCs).
  • This requires power supplies to regulate their output while maintaining ultra-low supply current in the nanoampere range.
  • Similarly, the TPS61094 can provide backup power in applications that require safe power-down or last-gasp communication during a power outage.
  • In addition to extending battery life, the industry's lowest-IQ buck/boost converter has a 2-A inductor current limit in boost operation.