Cochrane (organisation)

EyePoint Pharmaceuticals Expands Scientific Advisory Board with World-Renowned Retina Specialists

Retrieved on: 
Tuesday, April 2, 2024
Patient, MIB, ARI, Therapy, AAO, Research, Surgeon, Thomas Jefferson University, German Research Foundation, Chairperson, American Diabetes Association, Macular degeneration, SAB, FACS, Food, Cornell University, Empire, University, Castle Connolly Medical, Laborie (company), Publication, Emerita, AMD, FDA, Cochrane (organisation), Moorfields Eye Hospital, American Academy, Most, Consultant, Physician, Royal college, Diabetic retinopathy, Commander, Pharmaceutical industry

WATERTOWN, Mass., April 02, 2024 (GLOBE NEWSWIRE) -- EyePoint Pharmaceuticals, Inc. (NASDAQ: EYPT), a company committed to developing and commercializing therapeutics to improve the lives of patients with serious retinal diseases, today announced the appointment of leading global ophthalmologists to its Scientific Advisory Board (SAB), co-chaired by Carl Regillo M.D., FACS, Chief of the Retina Service at Wills Eye Hospital and Charles Wykoff, M.D., Ph.D., Director of Research of Retina Consultants of Texas. The SAB additions include Usha Chakravarthy, M.B.B.S., Ph.D.; Allen Ho, M.D. FACS FASRS, and Frank Holz, M.D., F.E.B.O., F.A.R.V.O. These three world-renowned retinal specialists will support advancement of the Company’s global clinical strategy ahead of the anticipated initiation of its Phase 3 pivotal trials in wet age-related macular degeneration (wet AMD) in the second half of this year. Additionally, the Company announced that the U.S. Food and Drug Administration (FDA) has conditionally accepted the trade name, DURAVYUTM (vorolanib intravitreal insert) for the Company’s lead product candidate, EYP-1901.

Key Points: 
  • “The SAB’s strategic counsel, global expertise, and scientific knowledge will be incredibly valuable during this critical time in EyePoint’s growth and expansion.
  • Dr. Chakravarthy has authored or co-authored over 400 publications, and she is invited to lecture in the UK and abroad.
  • FACS FASRS is Attending Surgeon, Director of Retina Research and Co-Director of the Retina Service of Wills Eye Hospital and Professor of Ophthalmology at Thomas Jefferson University.
  • He is a Board Member of the German Ophthalmological Society, and of the Club Jules Gonin and is past president of EURETINA.

Implications of Quebec's Vaping Flavour Ban: Long-Term Health and Economic Impacts Expected

Retrieved on: 
Thursday, August 3, 2023
Tempest, Legislation, Nicotine, Crime, Lobbying, Tobacco, Government, Risk, Growth, CVA, Health, McGill, Smoking, Counsel, Cochrane (organisation), Herbal cigarette, Maple syrup

Quebec’s flavour ban will therefore limit the efficacy of what has been proven to be one of the most effective tools for quitting smoking.

Key Points: 
  • Quebec’s flavour ban will therefore limit the efficacy of what has been proven to be one of the most effective tools for quitting smoking.
  • As a result of the new regulations, more than 90% of vaping liquids currently in use will be classified as illegal.
  • This move is expected to devastate Quebec’s vaping industry, which currently contributes nearly $150 million in excise and sales taxes to Quebec's economy.
  • This decision is a public health disaster that will have health, social and economic consequences for years to come,” said Tempest.

CDC Data Shows More US Children are Overexposed to Fluoride Than Ever Before

Retrieved on: 
Monday, May 8, 2023
Yang, Tissue, National Health and Nutrition Examination Survey, Ecotoxicology, Water, Prevalence, The United People of Canada, Government, Cochrane (organisation), CDC, Uric acid, National Health, Menstruation, Blood, Kidney, NHANES, Biophysical environment, Infant, Fluorosis, Sleep, Neurotoxicity, Korea Disease Control and Prevention Agency, Dental, Birth control, Dentistry, Phosphorus

NORTH SUTTON, N.H., May 8, 2023 /PRNewswire/ -- Government data shows that tens-of-millions of U.S. residents have visible signs of overexposure to fluoride.

Key Points: 
  • NORTH SUTTON, N.H., May 8, 2023 /PRNewswire/ -- Government data shows that tens-of-millions of U.S. residents have visible signs of overexposure to fluoride.
  • The US Centers For Disease Control's (CDC) National Health and Nutrition Examination Survey (NHANES) has consistently found skyrocketing rates of dental fluorosis, reports the Fluoride Action Network .
  • The CDC reported that 41% of adolescents (12 to 15) had dental fluorosis in 2004.
  • At the time, this was an increase of over 400% from the rates found 60 years prior.

Photocure: Nordic registry clinical data and multiple scientific programs at AUA 2023 Congress reinforce the benefits of Blue Light Cystoscopy

Retrieved on: 
Tuesday, May 2, 2023
Real-World Evidence, BLC, CME, Malignancy, Surgeon, Investigational New Drug, Registry, Hexyl aminolevulinate hydrochloride, Photocure, Isabella Tree, Neoplasm, Physician, AUA, Drug, Bladder cancer, Department of Urology, University of Virginia, Attention, Doctor of Philosophy, Biochemistry, Congress, Hospital, American Urological Association, MD, Patient, Skin, Webcast, Cystoscopy, TURBT, Cochrane (organisation), Conference, EAU, Pharmaceutical industry, NMIBC, Urology, Northwestern University

This Nordic Registry study, which is supported by Photocure, included data from 319 patients and 436 Blue Light Flexible Cystoscopies performed in the surveillance of NMIBC.

Key Points: 
  • This Nordic Registry study, which is supported by Photocure, included data from 319 patients and 436 Blue Light Flexible Cystoscopies performed in the surveillance of NMIBC.
  • The study results showed that flexible blue light cystoscopy with Hexvix®/Cysview®, as an adjunct to white light cystoscopy for surveillance of NMIBC, improves the detection of malignant lesions.
  • In the study, biopsies were taken from 452 lesions, showing malignancy in 126/409 (31%) lesions positive for blue light.
  • In 86 of the cystoscopies (20%), lesions were identified only by blue light.

Photocure: Nordic registry clinical data and multiple scientific programs at AUA 2023 Congress reinforce the benefits of Blue Light Cystoscopy

Retrieved on: 
Tuesday, May 2, 2023
Real-World Evidence, BLC, CME, Malignancy, Surgeon, Investigational New Drug, Registry, Hexyl aminolevulinate hydrochloride, Photocure, Isabella Tree, Neoplasm, Physician, AUA, Drug, Bladder cancer, Department of Urology, University of Virginia, Attention, Doctor of Philosophy, Biochemistry, Congress, Hospital, American Urological Association, MD, Patient, Skin, Webcast, Cystoscopy, TURBT, Cochrane (organisation), Conference, EAU, Pharmaceutical industry, NMIBC, Urology, Northwestern University

This Nordic Registry study, which is supported by Photocure, included data from 319 patients and 436 Blue Light Flexible Cystoscopies performed in the surveillance of NMIBC.

Key Points: 
  • This Nordic Registry study, which is supported by Photocure, included data from 319 patients and 436 Blue Light Flexible Cystoscopies performed in the surveillance of NMIBC.
  • The study results showed that flexible blue light cystoscopy with Hexvix®/Cysview®, as an adjunct to white light cystoscopy for surveillance of NMIBC, improves the detection of malignant lesions.
  • In the study, biopsies were taken from 452 lesions, showing malignancy in 126/409 (31%) lesions positive for blue light.
  • In 86 of the cystoscopies (20%), lesions were identified only by blue light.

New Cochrane Review Recognizes the Powerful Impact of Cranberry for UTI Prevention

Retrieved on: 
Thursday, April 27, 2023
Infection, Cochrane Library, Powder, UTI, Cranberry, Quality of life, Woman, Research, Meta-analysis, Systematic review, Doctor of Philosophy, Cranberry juice, Science, Rutgers University, Tablet, The United People of Canada, Incidence, Capsule, Proanthocyanidin, PAC, Risk, Bacteria, PACS, Health, Recurrence, Cochrane (organisation), News, Dietary supplement, Urinary tract infection

CARVER, Mass., April 27, 2023 /PRNewswire/ -- In the most comprehensive review to date, new findings published in The Cochrane Database of Systematic Reviews have positive news for those who suffer from urinary tract infections (UTIs). Cranberry juice, and cranberry supplements, have been shown to prevent and reduce the risk of repeat UTIs in women, children, and other at-risk individuals.

Key Points: 
  • Cranberry juice, and cranberry supplements, have been shown to prevent and reduce the risk of repeat UTIs in women, children, and other at-risk individuals.
  • The science has long shown that cranberry products can prevent UTIs, and now this review further bolsters evidence to prove their efficacy.
  • Study authors conducted a large-scale meta-analysis of 50 clinical trials, in which the objective was to assess the effectiveness of cranberry products in preventing UTIs in susceptible populations.
  • We have determined that PACs in juice-based products are most effective for UTI prevention and should be consumed daily2," says Howell.

Cranberry juice can prevent recurrent UTIs, but only for some people

Retrieved on: 
Wednesday, April 19, 2023
Review, Infection, Human, Life, Urine, Urinary tract infection, UTI, Phytochemical, Cranberry, Pelvis, Fungal infection, University, Clinical trial, Woman, Cochrane, Research, Fruit, Cranberry juice, Health policy, Sepsis, Vaccinium macrocarpon, Pain, Tablet, Vaccinium, Stinger, Pharmacist, Hospital, Patient, Risk, Blood, Coffee, Abdomen, Pregnancy, Bacteria, Health, Indigenous peoples, System, Probiotic, Cochrane (organisation), Escherichia coli, Update, Dietary supplement, Pharmaceutical industry

You might have also heard cranberries prevent urinary tract infections (UTIs).

Key Points: 
  • You might have also heard cranberries prevent urinary tract infections (UTIs).
  • The review didn’t look at the use of cranberry for the treatment of UTI – and cranberry juice cannot cure a UTI on its own.

Remind me, what is a UTI?

    • About one-third of women will have one at some point in their life.
    • They’re also common among elderly people and those with bladder issues caused by spinal cord injury or other conditions.
    • Typically, a UTI feels like peeing razor blades and the urine can be smelly, cloudy, and sometimes has blood in it.

What medicinal properties do cranberries have?

    • The First Peoples of North America have long known the benefits of eating cranberries, including their benefits for bladder problems.
    • Cranberries (Vaccinium macrocarpon) – a native fruit of North America – have a high concentration of proanthocyanidin, which protects the cranberry plant against microbes.
    • It was this apparent ability that researchers concluded was responsible for the cranberry’s medicinal properties.

The evolution of the evidence

    • The first Cochrane compilation of four clinical trials on this topic – published in 1998 – concluded the evidence was too poor to determine efficacy.
    • A Cochrane Review involves identifying of all the available peer-reviewed academic evidence on a health care or health policy topic.
    • As one of Cochrane’s most popular reviews, and the ever increasing volume of evidence, updating the review was important.

What’s new?

    • The recent increased volume of high-quality evidence has shown cranberry products work for people who experience recurrent UTI or are susceptible to UTI.
    • Recurrent UTIs are defined as two or more UTIs within six months, or three or more UTIs within a year.
    • We asked 5 experts

      What is still unclear is the formulation and dosage of cranberry products.

    • Jacqueline Stephens receives funding from NHMRC, Channel 7 Children's Research Foundation, Ferring Pharmaceuticals, and Flinders Foundation.

Casio Encourages Everyone To Stay Active During Depression Awareness Month

Retrieved on: 
Monday, October 18, 2021
Goal, Loneliness, Casiotone, Music therapy, Solution, Time, Awareness, Depression, Color, Android, Music, Creativity, Meta-analysis, Urethane, Multimedia, AA, Bluetooth, Exercise, IOS, Temperature, National, Jogging, Mental health, MSRP, Cochrane (organisation), Element, Mac, Research, Casio, CASIO, Quality of life

DOVER, N.J., Oct. 18, 2021 /PRNewswire/ --Observed during the month of October, Depression Awareness Month highlights the importance of maintaining a healthy and happy mindset.

Key Points: 
  • DOVER, N.J., Oct. 18, 2021 /PRNewswire/ --Observed during the month of October, Depression Awareness Month highlights the importance of maintaining a healthy and happy mindset.
  • Staying active is not always easy but discovering pastimes that appeal to you and satisfy different aspects of your emotional wellness can help.
  • A recent meta-analysis by Cochrane Reviews supports the long-standing belief that music therapy provides beneficial effects for people with depression.
  • Casio has strived to realize its corporate creed of "creativity and contribution" through the introduction of innovative and imaginative products.