LIF

New Study Finds Mouse Embryonic Stem Cells Have No Special Requirement for Threonine

Retrieved on: 
Wednesday, September 7, 2022
Threonine, Leukemia inhibitory factor, LIF, Experimental biology, Experimental Biology and Medicine, DRS, Methionine, Protein, Society for Experimental Biology and Medicine, Glutamine, State university system, Publishing, Serum, Stem cell, Biophysics, Department, Arginine, Cell, Organic acid, GLOBE, Physiology, Growth, Valine, Society, Vaccine, Medicine, MESC

The study, led by Dr. Jian Feng in the Department of Physiology and Biophysics at the State University of New York, Buffalo, finds that mouse embryonic stem cells do not have a unique requirement for threonine.

Key Points: 
  • The study, led by Dr. Jian Feng in the Department of Physiology and Biophysics at the State University of New York, Buffalo, finds that mouse embryonic stem cells do not have a unique requirement for threonine.
  • An influential study published in 2009 claims that the growth and proliferation of mouse embryonic stem cells (mESCs) have a unique dependence on threonine.
  • It has become accepted that mESCs have a special requirement for threonine to grow and multiply.
  • The present study thus set the record straight on the amino acid requirement of mESCs by finding that, just like most types of cells, mESCs do not have a special requirement for threonine.

W3 Storage Lab Raises $3 Million in Pre-Seed Financing Round

Retrieved on: 
Thursday, August 18, 2022
QTUM, Crypto, McKinsey & Company, Testnet, Non-fungible token, Industry, CEO, HKSE, AI, Technology, HTTP, Otter, Growth, VCS, Silicon, Semantic Web, Blockchain, Software as a service, Entrepreneurship, DNS, Marketing, Company, RMB, COO, DMC, VET, CTO, Ledger, LIF, IBM Network Control Program, Solution, Internet, SHA, USD, Cryptocurrency, Web3

SUNNYVALE, Calif., Aug. 18, 2022 /PRNewswire-PRWeb/ -- W3 Storage Lab, a Web3 decentralized application company, announced that it closed a pre-seed financing round of $3M. The round was co-led by Draper Dragon and OKX Blockdream Ventures with major participation from Lingfeng Capital and participation from other investors. Proceeds from the round will be used to grow its global team and fund operations.

Key Points: 
  • SUNNYVALE, Calif., Aug. 18, 2022 /PRNewswire-PRWeb/ -- W3 Storage Lab, a Web3 decentralized application company, announced that it closed a pre-seed financing round of $3M.
  • W3 Storage Lab has co-developed a next generation distributed storage ecosystem that is based on the public blockchain and cyfs://.
  • To facilitate a more efficient market for decentralized storage, W3 Storage Lab has also worked closely with the DMC Foundation as a major developer of the Datamall Coin ecology.
  • W3 Storage Lab is developing a series of killer applications for both consumers and enterprises that will make heavy use of decentralized storage.

GCM Grosvenor Issues 2021 Impact Report for its Labor Impact Fund, Highlighting $4 Billion of Projected Economic Impact

Retrieved on: 
Wednesday, June 29, 2022
Annual report, GCM, GLOBE, COVID-19, Ownership, Growth, U.S. Securities and Exchange Commission, GCMG, LIF, Partnership, Investment, Fund, GCM Grosvenor, Private Securities Litigation Reform Act, Labour, Solution, Regulation, Government, Telecom, Forward-looking statement, Renewable energy, Fossil fuel, Financial services, Bank

To date, the funds five investments have generated approximately 3.1 million union work-hours across multiple locations in the U.S. and Canada, and are projected to create over $4 billion in total economic impact.

Key Points: 
  • To date, the funds five investments have generated approximately 3.1 million union work-hours across multiple locations in the U.S. and Canada, and are projected to create over $4 billion in total economic impact.
  • The Funds performance and impact the Funds investments have made are testaments to this approach, and we are thrilled with these outcomes.
  • We are pleased that our investments continue to show progress, said GCM Grosvenor Managing Director Jorge Ramirez.
  • The Labor Impact Fund originates and executes infrastructure projects that leverage the inclusion of union labor as a contributing factor to enabling attractive risk-adjusted returns.

ChargeNet ‘Supercharges’ with $6.2M in Series Seed Funding

Retrieved on: 
Monday, January 10, 2022
Software, Restaurant, Bar, Professional Services, Alternative Energy, General Automotive, Energy, Technology, Automotive, Environment, Retail, Automotive Manufacturing, Finance, Manufacturing, Venus, Taco, ESG, CTO, Technology, COO, CA, MBA, CEO, LIF, EV, Public policy, San Onofre Nuclear Generating Station, Software as a service, Business–IT alignment, Tech Coast Angels, MIT, Taco Bell, Engineering, GHG, Director, Partnership, Board, Renewable energy, Fast food, ChargeNet, Aligned Climate Capital, CHARGENET, ALIGNED CLIMATE CAPITAL

ChargeNet , a software platform start-up that integrates electric vehicle (EV) fast chargers, energy storage and solar power with a payment system, has closed a $6.2 million Series Seed financing round led by Aligned Climate Capital .

Key Points: 
  • ChargeNet , a software platform start-up that integrates electric vehicle (EV) fast chargers, energy storage and solar power with a payment system, has closed a $6.2 million Series Seed financing round led by Aligned Climate Capital .
  • ChargeNet is currently developing fast, solar powered EV charging stations strategically located in quick-serve restaurant parking lots.
  • The key to our partnership with Aligned Climate Capital is our shared values, said ChargeNet CEO and co-founder Tosh Dutt.
  • The proceeds from the Series Seed investment will be used to execute on ChargeNets development pipeline of solar powered charging stations, hire employees, and fund the companys growth strategy.

AmericanSenior.com, a HighTechLending company debuts new Reverse Mortgage television commercial campaign

Retrieved on: 
Wednesday, November 17, 2021
Reverse mortgage, Senior, Wholesaling, FBN, Insurance, Industry, Retirement, FHA, Social, DBA, Broker, Program, LIF, Reverse, Goal, Family, SVP, HUD, Fannie Mae, Investment, Risk, IMPAC, Social Security, Television, CNN, Life insurance, Bank, Real estate

AmericanSenior is a HighTechLending company and operates in most states across the U.S. HighTechLending DBA AmericanSenior also offers the conventional 30-year fixed mortgage if that is best option for the senior.

Key Points: 
  • AmericanSenior is a HighTechLending company and operates in most states across the U.S. HighTechLending DBA AmericanSenior also offers the conventional 30-year fixed mortgage if that is best option for the senior.
  • He opened HighTechLending in June of 2006 as a mortgage bank specializing in high technology paperless loan process.
  • HighTechLending offers Fannie Mae (30-year conventional fixed mortgage), FHA and Reverse Mortgages.
  • HighTechLending, Inc. is a mortgage bank focused on providing Brokers with price, product, and exceptional customer service.

Court of Appeal revokes BCSC preservation order on registered retirement accounts

Retrieved on: 
Monday, November 15, 2021
Legislation, Court of Appeals of Virginia, Retirement, Security (finance), British Columbia Securities Commission, PBSA, British Columbia Court of Appeal, Commission, Seizure, Securities Act of 1933, Mr. Lif, Federation, Sale, BCSC, Fraud, Frank Pasquill, Employee Retirement Income Security Act of 1974, LIF, Online gambling, Life insurance

The preservation order prevented Pasquill, who owes the BCSC $36.7 million, from withdrawing or transferring funds from two life income fund (LIF) accounts, totaling $644,951 as of April 2020.

Key Points: 
  • The preservation order prevented Pasquill, who owes the BCSC $36.7 million, from withdrawing or transferring funds from two life income fund (LIF) accounts, totaling $644,951 as of April 2020.
  • The BCSC issued the preservation order under amendments to the Securities Act in 2020 that allow the Commission to preserve property in registered accounts after a sanctions decision has been issued by a panel.
  • Pasquill contended that the preservation order is a form of "execution, seizure or attachment," and thePension Benefits Standards Act (PBSA)exempts LIFs from the preservation order.
  • The Court of Appeal agreed with Pasquill that the PBSA exempts his LIF accounts from the preservation order.

BrainStorm Announces Scientific Presentation of NurOwn® Exosome Preclinical ARDS Data at NYSCF 2021 VIRTUAL Meeting

Retrieved on: 
Monday, October 18, 2021
Gastric lavage, EMA, Exo, Cell, Microsoft, NTFS, LPS, Sev Ohanian, Amphiregulin, California Institute for Regenerative Medicine, Respiratory disease, European Medicines Agency, Poster, National, CIRM, Mortality, Therapy, MS, HGF, FDA, Exosome, Multiple sclerosis, Orphan drug, Regulation of food and dietary supplements by the U.S. Food and Drug Administration, Neurodegeneration, Food, Phrase, Hepatocyte growth factor, Amyotrophic lateral sclerosis, Company, MSC, Annual report, Brainstorm, California, LIF, AREG, Regenerative medicine, Safety, NASDAQ, Leukemia inhibitory factor, Research, BALF, TSG-6, Pharmaceutical industry, Medical imaging, Vaccine

The NurOwntechnology platform (autologous MSC-NTF cells) represents a promising investigational therapeutic approach to targeting disease pathways important in neurodegenerative disorders.

Key Points: 
  • The NurOwntechnology platform (autologous MSC-NTF cells) represents a promising investigational therapeutic approach to targeting disease pathways important in neurodegenerative disorders.
  • MSC-NTF cells are produced from autologous, bone marrow-derived mesenchymal stem cells (MSCs) that have been expanded and differentiated ex vivo.
  • About BrainStorm Cell Therapeutics Inc.
    BrainStorm Cell Therapeutics Inc. is a leading developer of innovative autologous adult stem cell therapeutics for debilitating neurodegenerative diseases.
  • Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements.

Northern Biologics Reports Phase I Data Update for MSC-1, an Anti-LIF Antibody, at ESMO

Retrieved on: 
Friday, September 27, 2019
Oncology, Health, Clinical trials, Pharmaceutical, Biotechnology, LIF, Northern Biologics

The study completed enrollment in early March, with 41 patients enrolled in nine months, in dose cohorts ranging from 75 mg to 1,500 mg Q3W.

Key Points: 
  • The study completed enrollment in early March, with 41 patients enrolled in nine months, in dose cohorts ranging from 75 mg to 1,500 mg Q3W.
  • The treatment was well-tolerated with no dose-limiting toxicities or tolerability issues observed at any dose.
  • Durable saturation of peripheral LIF in a pharmacodynamic assay in patients supported the selection of the recommended Phase 2 dose for further development.
  • Northern Co-Founder Joan Seoane first elucidated a role for the cytokine in cancer in a seminal 2009 publication in Cancer Cell.