Glycosidic bond

PLAMECA's QUICKISEN is a Natural Solution to Constipation

Retrieved on: 
Tuesday, September 5, 2023

FORT LAUDERDALE, Fla., Sept. 5, 2023 /PRNewswire/ -- Constipation is a common concern among all Americans. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) explains that constipation is common among all ages and populations in the U.S. Symptoms occur in approximately 16% of the population, with the number of cases rising to 33% among those 60 years and older. Cleveland Clinic adds that constipation most often occurs due to a change in diet or routine — as well as an inadequate intake of fiber.

Key Points: 
  • The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) explains that constipation is common among all ages and populations in the U.S.
  • Cleveland Clinic adds that constipation most often occurs due to a change in diet or routine — as well as an inadequate intake of fiber.
  • "Sometimes, the simplest solution to constipation is to consume foods with more fibrous content," explains Óscar Fernández, managing director of the health brand PLAMECA.
  • In other words, QUICKISEN won't have the intense effect of those stronger constipation tools.

RVL Pharmaceuticals plc to Discuss Second Quarter 2023 Financial Results and Provide Commercial Update

Retrieved on: 
Wednesday, August 2, 2023

UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is indicated for the treatment of acquired blepharoptosis in adults.

Key Points: 
  • UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is indicated for the treatment of acquired blepharoptosis in adults.
  • Ptosis may be associated with neurologic or orbital diseases such as stroke and/or cerebral aneurysm, Horner syndrome, myasthenia gravis, external ophthalmoplegia, orbital infection and orbital masses.
  • Consideration should be given to these conditions in the presence of ptosis with decreased levator muscle function and/or other neurologic signs.
  • Caution is advised in patients taking monoamine oxidase inhibitors which can affect the metabolism and uptake of circulating amines.

RVL Pharmaceuticals plc to Discuss First Quarter 2023 Financial Results and Provide Commercial Update

Retrieved on: 
Thursday, May 4, 2023

Ptosis may be associated with neurologic or orbital diseases such as stroke and/or cerebral aneurysm, Horner syndrome, myasthenia gravis, external ophthalmoplegia, orbital infection and orbital masses.

Key Points: 
  • Ptosis may be associated with neurologic or orbital diseases such as stroke and/or cerebral aneurysm, Horner syndrome, myasthenia gravis, external ophthalmoplegia, orbital infection and orbital masses.
  • Consideration should be given to these conditions in the presence of ptosis with decreased levator muscle function and/or other neurologic signs.
  • Advise UPNEEQ patients with cardiovascular disease, orthostatic hypotension, and/or uncontrolled hypertension or hypotension to seek medical care if their condition worsens.
  • Caution is advised in patients taking monoamine oxidase inhibitors which can affect the metabolism and uptake of circulating amines.

RVL Pharmaceuticals plc to Discuss Fourth Quarter and Full Year 2022 Financial Results and Provide Commercial Update

Retrieved on: 
Wednesday, March 15, 2023

UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is indicated for the treatment of acquired blepharoptosis in adults.

Key Points: 
  • UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is indicated for the treatment of acquired blepharoptosis in adults.
  • Consideration should be given to these conditions in the presence of ptosis with decreased levator muscle function and/or other neurologic signs.
  • Advise UPNEEQ patients with cardiovascular disease, orthostatic hypotension, and/or uncontrolled hypertension or hypotension to seek medical care if their condition worsens.
  • Caution is advised in patients taking monoamine oxidase inhibitors which can affect the metabolism and uptake of circulating amines.

Global Pulmonary Arterial Hypertension (PAH) Drugs Market Report 2022 to 2027: Key Players Include Arena Pharmaceuticals, AstraZeneca, Bayer Aktiengesellschaft and Daiichi Sankyo - ResearchAndMarkets.com

Retrieved on: 
Friday, February 3, 2023

Pulmonary arterial hypertension (PAH) refers to a life-threatening medical condition characterized by high blood pressure in the arteries that connect the heart to the lungs.

Key Points: 
  • Pulmonary arterial hypertension (PAH) refers to a life-threatening medical condition characterized by high blood pressure in the arteries that connect the heart to the lungs.
  • The increasing prevalence of cardiovascular and pulmonary disorders is one of the key factors driving the growth of the market.
  • The publisher provides an analysis of the key trends in each sub-segment of the global pulmonary arterial hypertension (PAH) drugs market report, along with forecasts at the global, regional and country level from 2022-2027.
  • Our report has categorized the market based on drug class, route of administration and end user.

RVL Pharmaceuticals plc Announces Preliminary Fourth Quarter Sequential Growth of 21% and Full Year 2022 UPNEEQ® Net Product Sales

Retrieved on: 
Monday, January 9, 2023

BRIDGEWATER, N.J., Jan. 09, 2023 (GLOBE NEWSWIRE) -- RVL Pharmaceuticals plc (Nasdaq: RVLP) (“RVL” or the “Company”), a specialty pharmaceutical company, today announced preliminary fourth quarter and full year 2022 net product sales of UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1%, the first and only U.S. Food and Drug Administration (“FDA”)-approved ophthalmic solution for blepharoptosis, or droopy eyelids, of approximately $12.1 million and $36.5 million, respectively. The preliminary fourth quarter 2022 net product sales of UPNEEQ represent a sequential increase of 21% from the third quarter 2022. The Company also announced that from February through year-end 2022 it had received orders from approximately 4,300 cumulative unique medical aesthetics practices.

Key Points: 
  • The preliminary fourth quarter 2022 net product sales of UPNEEQ represent a sequential increase of 21% from the third quarter 2022.
  • “We are proud of our progress in the fourth quarter, notably the continued upward trajectory of net product sales for UPNEEQ.
  • On a full-year basis, we expect our UPNEEQ revenues to exceed $36 million, representing nearly 400% growth over 2021.
  • The financial and operating data for the fourth quarter of 2022 and for the full year 2022 is preliminary and may change.

RVL Pharmaceuticals plc to Present at the Cantor Medical & Aesthetic Dermatology, Ophthalmology & MedTech/Diagnostic Conference

Retrieved on: 
Thursday, December 1, 2022

Consideration should be given to these conditions in the presence of ptosis with decreased levator muscle function and/or other neurologic signs.

Key Points: 
  • Consideration should be given to these conditions in the presence of ptosis with decreased levator muscle function and/or other neurologic signs.
  • Advise UPNEEQ patients with cardiovascular disease, orthostatic hypotension, and/or uncontrolled hypertension or hypotension to seek medical care if their condition worsens.
  • Advise patients to seek medical care if signs and symptoms of potentiation of vascular insufficiency develop.
  • Caution is advised in patients taking monoamine oxidase inhibitors which can affect the metabolism and uptake of circulating amines.

RVL Pharmaceuticals plc to Discuss Third Quarter 2022 Financial Results and Provide Commercial Update

Retrieved on: 
Thursday, November 3, 2022

UPNEEQ (oxymetazoline hydrochloride ophthalmic solution), 0.1% is indicated for the treatment of acquired blepharoptosis in adults.

Key Points: 
  • UPNEEQ (oxymetazoline hydrochloride ophthalmic solution), 0.1% is indicated for the treatment of acquired blepharoptosis in adults.
  • Ptosis may be associated with neurologic or orbital diseases such as stroke and/or cerebral aneurysm, Horner syndrome, myasthenia gravis, external ophthalmoplegia, orbital infection and orbital masses.
  • Consideration should be given to these conditions in the presence of ptosis with decreased levator muscle function and/or other neurologic signs.
  • RVL Pharmaceuticals plc is a specialty pharmaceutical company focused on the commercialization of UPNEEQ (oxymetazoline hydrochloride ophthalmic solution), 0.1%, for the treatment of acquired blepharoptosis, or low-lying eyelid, in adults.

RVL Pharmaceuticals plc Announces Preliminary Third Quarter 2022 UPNEEQ® Net Product Sales

Retrieved on: 
Tuesday, October 18, 2022

BRIDGEWATER, N.J., Oct. 18, 2022 (GLOBE NEWSWIRE) -- RVL Pharmaceuticals plc (Nasdaq: RVLP) (“RVL” or the “Company”), a specialty pharmaceutical company, today announced preliminary third quarter 2022 net product sales of UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1%, the first and only U.S. Food and Drug Administration (“FDA”)-approved ophthalmic solution for blepharoptosis, or droopy eyelids, of approximately $10.0 million. The Company also announced that from February through September of 2022 it had received orders from approximately 3,500 cumulative unique medical aesthetics practices. RVL further revised its guidance for net product sales of UPNEEQ for the fourth quarter of 2022, indicating an expectation of $12 to $14 million, representing sequential growth of 20% to 40% compared to the third quarter of 2022.

Key Points: 
  • --Expects third quarter 2022 preliminary UPNEEQ net product sales of approximately $10.0 million, representing an increase of 19% over the second quarter 2022--
    --Third quarter 2022 net product sales growth contributed to approximately $24.4 million in sales for the nine months ended September 30, 2022--
    --Approximately 3,500 cumulative unique medical aesthetics practices placed orders for UPNEEQ through the end of the third quarter 2022, a 59% increase from the end of the second quarter 2022--
    --Anticipates fourth quarter 2022 UPNEEQ net product sales to grow approximately 20% - 40% over the third quarter 2022, representing sales of approximately $12 - $14 million--
    BRIDGEWATER, N.J., Oct. 18, 2022 (GLOBE NEWSWIRE) -- RVL Pharmaceuticals plc (Nasdaq: RVLP) (RVL or the Company), a specialty pharmaceutical company, today announced preliminary third quarter 2022 net product sales of UPNEEQ (oxymetazoline hydrochloride ophthalmic solution), 0.1%, the first and only U.S. Food and Drug Administration (FDA)-approved ophthalmic solution for blepharoptosis, or droopy eyelids, of approximately $10.0 million.
  • RVL further revised its guidance for net product sales of UPNEEQ for the fourth quarter of 2022, indicating an expectation of $12 to $14 million, representing sequential growth of 20% to 40% compared to the third quarter of 2022.
  • The financial and operating data for the third quarter of 2022 is preliminary and may change.
  • In addition, the Companys estimate of UPNEEQ net product sales for the third quarter of 2022 should not be viewed as a substitute for full financial statements for the third quarter of 2022 prepared in accordance with U.S. generally accepted accounting standards.

RVL Pharmaceuticals plc to Present at the H.C. Wainwright 24th Annual Global Investment Conference

Retrieved on: 
Tuesday, August 30, 2022

Ptosis may be associated with neurologic or orbital diseases such as stroke and/or cerebral aneurysm, Horner syndrome, myasthenia gravis, external ophthalmoplegia, orbital infection and orbital masses.

Key Points: 
  • Ptosis may be associated with neurologic or orbital diseases such as stroke and/or cerebral aneurysm, Horner syndrome, myasthenia gravis, external ophthalmoplegia, orbital infection and orbital masses.
  • Consideration should be given to these conditions in the presence of ptosis with decreased levator muscle function and/or other neurologic signs.
  • Advise UPNEEQ patients with cardiovascular disease, orthostatic hypotension, and/or uncontrolled hypertension or hypotension to seek medical care if their condition worsens.
  • Caution is advised in patients taking monoamine oxidase inhibitors which can affect the metabolism and uptake of circulating amines.