Isogenic human disease models

Government of Canada teams up with Indigenous partners, Bruce Power and the medical isotope community to fight cancer

Retrieved on: 
Tuesday, June 27, 2023

The partnership includes Indigenous communities, Ontario’s nuclear industry, and leading research facilities, academics, and firms working to commercialize novel therapies.

Key Points: 
  • The partnership includes Indigenous communities, Ontario’s nuclear industry, and leading research facilities, academics, and firms working to commercialize novel therapies.
  • This funding will ultimately enable a pan-Canadian consortium – the Canadian Medical Isotope Ecosystem (CMIE) – to advance and accelerate the development of the next generation of novel medical isotopes and technologies.
  • “Canada is a world leader in medical isotope research and production, and Bruce Power is proud to be among the innovative companies that places Canada at the forefront of nuclear medicine,” said Mike Rencheck, Bruce Power’s President and CEO.
  • “Our government is proud to partner in the creation of the Canadian Medical Isotope Ecosystem, which includes support for the SON First Nations communities’ partnership with Bruce Power to innovate in the fight against cancer,” said Minister Champagne.

Isotope Production System begins commercial production of cancer-fighting lutetium-177

Retrieved on: 
Monday, October 24, 2022

The IPS will provide reliable, industrial-scale production of lutetium-177, a medical isotope used for targeted cancer therapeutics.

Key Points: 
  • The IPS will provide reliable, industrial-scale production of lutetium-177, a medical isotope used for targeted cancer therapeutics.
  • Todays announcement is a huge step forward in advancing Ontario as a world leader of isotope production in the fight against cancer.
  • It is with great pride that we at Bruce Power, along with our partners at Isogen, ITM and Saugeen Ojibway Nation, celebrate the successful commencement of commercial operation of the worlds first large-scale Isotope Production System for the production of lutetium-177, said Mike Rencheck, Bruce Powers President and CEO.
  • lutetium-177 to health care facilities around the world, and the isotope has been successfully used in various clinical and commercial radiopharmaceutical cancer treatments.

ITM: Isotope Production System Begins Commercial Production of Cancer-Fighting Lutetium-177

Retrieved on: 
Monday, October 24, 2022

It marks the first-of-its-kind achievement of a commercial power reactor with additional capability to commercially produce short-lived medical isotopes.

Key Points: 
  • It marks the first-of-its-kind achievement of a commercial power reactor with additional capability to commercially produce short-lived medical isotopes.
  • The IPS will provide reliable, industrial-scale production of lutetium-177, a medical isotope used for targeted cancer therapeutics.
  • Todays announcement is a huge step forward in advancing Ontario as a world leader of isotope production in the fight against cancer.
  • lutetium-177 to health care facilities around the world, and the isotope has been successfully used in various clinical and commercial radiopharmaceutical cancer treatments.

Bruce Power to explore production of cancer-fighting medical isotope yttrium-90 for global distribution

Retrieved on: 
Monday, October 3, 2022

Medical isotopes save lives and Ontario is primed to become an isotope superpower, said Ontarios Energy Minister Todd Smith.

Key Points: 
  • Medical isotopes save lives and Ontario is primed to become an isotope superpower, said Ontarios Energy Minister Todd Smith.
  • Additionally, Bruce Power will soon become the first nuclear power reactor operator to commercially produce lutetium-177 through an innovative Isotope Production System (IPS).
  • The IPS is a first-of-its-kind solution to produce short-lived medical isotopes in a commercial reactor and will provide unprecedented capacity, redundancy and scale for medical isotope production.
  • Isogen will also work with Bruce Power and Boston Scientific on the feasibility of yttrium-90 production using the IPS.

New Isotope Production System at Bruce Power successfully produces first medical isotope

Retrieved on: 
Tuesday, June 21, 2022

This milestone was achieved using a new Isotope Production System (IPS) that was installed in Bruce Powers Unit 7 during a recent planned maintenance outage.

Key Points: 
  • This milestone was achieved using a new Isotope Production System (IPS) that was installed in Bruce Powers Unit 7 during a recent planned maintenance outage.
  • The IPS successfully irradiated targets to produce lutetium-177, a medical isotope used in precision oncology for targeted therapy of a growing number of cancers.
  • As part of commissioning activities, ytterbium-176 was successfully irradiated using the IPS, designed and installed by Isogen, to produce lutetium-177.
  • The exclusive access to the new Isotope Production System will allow ITM to further scale our global pharmaceutical n.c.a.

ITM: New Isotope Production System at Bruce Power Successfully Produces First Medical Isotope

Retrieved on: 
Tuesday, June 21, 2022

This milestone was achieved using a new Isotope Production System (IPS) that was installed in Bruce Powers Unit 7 during a recent planned maintenance outage.

Key Points: 
  • This milestone was achieved using a new Isotope Production System (IPS) that was installed in Bruce Powers Unit 7 during a recent planned maintenance outage.
  • The IPS successfully irradiated targets to produce lutetium-177, a medical isotope used in Precision Oncology for targeted therapy of a growing number of cancers.
  • We applaud Bruce Powers commitment to innovation that supports the continuous production of both electricity and medical isotopes, and to harnessing the therapeutic power of nuclear energy.
  • The exclusive access to the new Isotope Production System will allow ITM to further scale our global pharmaceutical n.c.a.

Bruce Power establishes new Ontario-based medical isotope hub to assist in global cancer fight

Retrieved on: 
Thursday, March 10, 2022

The new Ontario Isotope Innovation Hub will position Ontario as a global leader in the production of life-saving medical isotopes and ensure that the province is at the forefront of isotope research, development and innovation.

Key Points: 
  • The new Ontario Isotope Innovation Hub will position Ontario as a global leader in the production of life-saving medical isotopes and ensure that the province is at the forefront of isotope research, development and innovation.
  • Kinectrics Centre for Medical Isotopes & Nuclear Chemistry will transform innovative ideas and concepts into new Made-in-Ontario medical isotope products and services.
  • The Ontario Isotope Innovation Hub is a huge step forward in ensuring our province continues to lead when it comes to this important work.
  • The EOI will leverage the newly-installed, Made-in-Ontario, Isotope Production System (IPS) at Bruce Power, designed and manufactured by Isogen, which will be a cornerstone of the hub.

ITM: Installation of New Isotope Production System at Bruce Power to Produce Medical Isotopes for Cancer Therapy Completed

Retrieved on: 
Monday, January 24, 2022

This system will also have the ability to produce other isotopes for medical uses over the long term.

Key Points: 
  • This system will also have the ability to produce other isotopes for medical uses over the long term.
  • Ontario is leading the way in the production and supply of medical isotopes around the world, said Hon.
  • Im proud of the innovative work being done by Bruce Power and its partners in the supply chain, including Framatome and Kinectrics.
  • Isogens enabling partnerships with Bruce Power and ITM allows us to produce the worlds largest and most reliable supply of life-saving, short-lived, therapeutic medical isotopes.

Bruce Power receives regulatory approval for new lifesaving medical isotope production

Retrieved on: 
Friday, September 24, 2021

This is another important step forward to utilize our CANDU reactors to provide a new large-scale capacity for production in the medical isotope supply chain, cementing Canadas place as a global isotope superpower.

Key Points: 
  • This is another important step forward to utilize our CANDU reactors to provide a new large-scale capacity for production in the medical isotope supply chain, cementing Canadas place as a global isotope superpower.
  • Ontario continues to position itself as a world leader in the production of life-saving medical isotopes, said Energy Minister Todd Smith.
  • Todays announcement is a big step forward in furthering the goal of long-term, sustainable, and flexible production of medical isotopes at the Bruce Power site.
  • The work to install the Isotope Production System is a part of the ongoing Life-Extension Program at the Bruce Power site, which began in 2016 and remains on track.