Utrecht University

• Philadelphia, PA, March 28, 2024 (GLOBE NEWSWIRE) -- Society for Industrial and Applied Mathematics (SIAM) is pleased to announce the 2024 Class of SIAM Fellows.
• Through their various contributions, SIAM Fellows form a crucial group of individuals helping to advance the fields of applied mathematics, computational science, and data science.
• Hans De Sterck, University of Waterloo, is being recognized for contributions to scientific computing methods including multilevel and nonlinear solvers, and for exemplary scientific leadership and service to SIAM.
• Fred S. Roberts, Rutgers University, is being recognized for distinguished research in discrete mathematics, leadership of major research centers, and service to SIAM.

• Dr. Bernards is also a member of LIXTE’s Board of Directors.
• In his presentation, “Unexpected, but Highly Synergistic Combinations for Cancer Therapy,” Dr. Bernards will present data on how stress imposed onto colon cancer cells by LB-100 drives cancer cells to evolve to less cancerous behavior.
• “The findings underscore the unique and what we believe to be exciting features and mechanism of action of LIXTE’s PP2A inhibitor, LB-100,” said Dr. James Miser, LIXTE’s Chief Medical Officer.
• “While conventional cancer drugs aim to inhibit oncogenic signaling, which tends to drive cancer cells into more aggressive behavior, LB-100 does exactly the opposite, overloading oncogenic signaling, and thereby forcing cells to downregulate the signals that are characteristic for cancer cells.

• FertilityIQ, the global leader for fertility and family-building digital education, today announced the first-of-its-kind menopause education offering.
• The complete educational offering for women, patients, and employees offers crucial information for those going through perimenopause and the menopause transition.
• "Great education is critical to helping women through menopause.
• FertilityIQ's global courses are a valuable resource for patients, spouses, and employers," says Dr. Nick Panay, the current president of the International Menopause Society and past Chair of the British Menopause Society.

• Sudan and Egypt consider the US$4.6 billion dam a threat to vital water supplies.
• This is just one example of how conflicts can arise between states that share river basins.
• Although cooperation historically prevails over conflict and large-scale violent international conflicts haven’t happened so far, tensions over water have long existed.
• If nations improve water use, strengthen cooperation and do more to prevent or mitigate conflict, this number drops to 536 million.
• Water treaties and strong river basin organisations increase the likelihood of long-term, stable cooperation between states.

Our research

• It looked at hydroclimatic, governance and socio-economic risk factors.
• Combining these factors provided an idea of the overall conflict risk per transboundary river basin.
• A lack of cooperation between countries can lead to a loss of benefits that could arise from joint activities.

Our findings

• In Africa, this number includes people living in Eritrea, Ethiopia, Rwanda, Uganda, Kenya, Somalia, Burkina Faso, Mauritania and Niger.
• In the high ambition scenario – which implies improved water use practices and rising institutional resilience – this number decreases to 536 million.
• Under this scenario, 724 million people would be living in very high to high conflict-risk basins by 2050.

What it means

• Seven of these dams would be in Ethiopia, and the other four would be in South Sudan.
• The construction of these dams would be happening alongside rising water shortages, high water dependencies and limited economic resources to deal with water-related risks.
• In these two basins, multiple issues, such as local conflict, low human development and limited water availability already collide today.
• For example, when large hydropower dams are built, their operation must not hinder the climate adaptation goals of the wider region.