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Tonix Pharmaceuticals Announces Research Indicating Pre-Existing Fibromyalgia-Type Symptoms May Increase the Risk of Developing Long COVID

Retrieved on: 
Wednesday, January 31, 2024

CHATHAM, N.J., Jan. 31, 2024 (GLOBE NEWSWIRE) -- Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP) (Tonix or the Company), a biopharmaceutical company with marketed products and a pipeline of development candidates and currently focused on preparing a New Drug Application (NDA) for Tonmya (formerly TNX-102 SL, sublingual cyclobenzaprine HCl) for the management of fibromyalgia, today announced the online publication of a research paper in the Journal Pain. The article titled, “Chronic Overlapping Pain Conditions Increase the Risk of Long COVID Features, Regardless of Acute COVID Status,” by Bergmans, et al. 1, found that patients with pre-existing chronic overlapping pain conditions (COPCs) had an increased risk of being diagnosed with symptoms of Long COVID1. Faculty at the University of Michigan directed the research. Commentary on the article titled, “A step towards better understanding chronic overlapping pain conditions” by Fitzcharles, et al,2 is in the same issue of the journal.

Key Points: 
  • The article titled, “Chronic Overlapping Pain Conditions Increase the Risk of Long COVID Features, Regardless of Acute COVID Status,” by Bergmans, et al.
  • 1, found that patients with pre-existing chronic overlapping pain conditions (COPCs) had an increased risk of being diagnosed with symptoms of Long COVID1.
  • COPCs include fibromyalgia, chronic fatigue syndrome, migraine headache, irritable bowel syndrome, endometriosis and low back pain.
  • “Tonix is studying TNX-102 SL for the management of fibromyalgia (conditionally approved by U.S. Food and Drug Administration as “Tonmya”) and for fibromyalgia-type Long COVID.

Barkemeyer Law Firm Announcing New Office Opening in Lafayette, Louisiana

Retrieved on: 
Sunday, September 17, 2023

LAFAYETTE, La., Sept. 17, 2023 /PRNewswire-PRWeb/ -- The Barkemeyer Law Firm has now made an additional office in the great city of Lafayette, Louisiana. We are now able to offer our premium criminal defense and DWI defense legal services to those in need in southwest Louisiana. Our criminal defense attorneys and DWI lawyers in Lafayette are able to defend clients in Lafayette, Opelousas, Lake Charles, Beauregard, Acadia, Vermillion, Evangeline, St. Martin, Iberia and Jefferson Davis parishes and more. Our lawyers represent clients arrested for theft, shoplifting, DWI, DUI, hit and run, illegal carrying of weapons, gun charges, resisting an officer, flight from an officer, reckless driving, criminal damage to property, disturbing the peace, fraud, forgery, bench warrants, fugitive warrants, trespass, assault, battery, bank fraud, felony and misdemeanor charges, and more.

Key Points: 
  • The Barkemeyer Law Firm has opened its new office in the heart of downtown Lafayette, offering criminal defense representation to those who have been arrested or received a summons in Lafayette and the surrounding areas.
  • LAFAYETTE, La., Sept. 17, 2023 /PRNewswire-PRWeb/ -- The Barkemeyer Law Firm has now made an additional office in the great city of Lafayette, Louisiana.
  • We are now able to offer our premium criminal defense and DWI defense legal services to those in need in southwest Louisiana.
  • Regardless is the criminal arrest is for a misdemeanor or felony or if the charge is in Lafayette District Court or Lafayette City Court, we can help.

GoPro Launches $399 HERO12 Black with Up to 2x Longer Runtimes, 5.3K and 4K HDR Video, Wireless Audio Support for Apple AirPods + Other Bluetooth® Devices, Plus Powerful New Camera Features for Both Professional + Casual Enthusiasts

Retrieved on: 
Wednesday, September 6, 2023

SAN MATEO, Calif., Sept. 6, 2023 /PRNewswire/ -- Today, GoPro (NASDAQ: GPRO) announced its new HERO12 Black camera, raising the bar yet again for the small, rugged, ultra-versatile cameras the company is famous for.

Key Points: 
  • "HERO12 Black resets the bar for immersive life-capture," says GoPro CEO and Founder Nicholas Woodman.
  • GoPro is also expanding its software experience and GoPro subscriber benefits with the launch of its new Quik desktop app.
  • This convenient, new remote will be compatible with: HERO12 Black, HERO11 Black, HERO11 Black Mini and HERO10 Black.
  • GoPro will also host a HERO12 Black "Ask Me Anything" virtual event exclusively for GoPro subscribers on September 7.

Feed me: 4 ways to take control of social media algorithms and get the content you actually want

Retrieved on: 
Wednesday, May 10, 2023

Whether it’s Facebook’s News Feed or TikTok’s For You page, social media algorithms are constantly making behind-the-scenes decisions to boost certain content – giving rise to the “curated” feeds we’ve all become accustomed to. But does anyone actually know how these algorithms work? And, more importantly, is there a way to “game” them to see more of the content you want?Optimising for engagementTheir main goal is to sustain your attention for as long as possible, in a process called “optimising for engagement”.

Key Points: 


Whether it’s Facebook’s News Feed or TikTok’s For You page, social media algorithms are constantly making behind-the-scenes decisions to boost certain content – giving rise to the “curated” feeds we’ve all become accustomed to. But does anyone actually know how these algorithms work? And, more importantly, is there a way to “game” them to see more of the content you want?

Optimising for engagement

    • Their main goal is to sustain your attention for as long as possible, in a process called “optimising for engagement”.
    • Sort all of the user’s friend updates – including photos, statuses and more – in reverse chronological order (newer posts first).
    • For instance, Twitter’s “For You” recommendation algorithm is based on a neural network that uses about 48 million parameters!

A black box

    • Although this might seem simple, algorithms are typically “black boxes” that have their inner workings hidden.
    • Trying to “game” an algorithm is like trying to solve a 3D box puzzle without any instructions and without being able to peer inside.
    • You can only use trial-and-error – manipulating the pieces you see on the outside, and gauging the effects on the overall state of the box.

So what can you do?


    That said, there are some ways you can try to curate your social media to serve you better. Since algorithms are powered by your data and social media habits, a good first step is to change these habits and data – or at least understand how they may be shaping your online experience.

1. Engage with content you trust and want more of

    • Basil, who is fascinated by space, knows they would do well to follow NASA and steer clear of users who believe the Moon is made of cheese.
    • Think critically about the accounts and pages you follow, asking questions such as Who is the author of this content?
    • The higher the quality of the content you engage with, the more likely it is that you’ll be recommended similarly valuable content (rather than fake news or nonsense).

2. Be stingy with your information

    • Social media companies know more about you than you think – from your location, to your perceived interests, to your activities outside the app, and even the activities and interests of your social circle!
    • If you limit the information you provide about yourself, you limit the extent to which the algorithm can target you.

3. Use your settings

    • Adjusting your privacy and personalisation settings will further help you avoid being microtargeted through your feed.
    • The “Off-Facebook Activity” setting allows you to break the link between your Facebook account and your activities outside of Facebook.

4. Get (dis)engaged



    A final piece of advice is to simply disengage with content you don’t want in your feed. This means:
    • Even if they do this, the algorithm won’t necessarily “forget” all their data: it might still exist in caches or backups.
    • Because of how complex and pervasive algorithms are, you can’t guarantee control over them.
    • Nonetheless, you shouldn’t let tech giants’ bottom line dictate how you engage with social media.

EQS-News: Linde plc: Linde Reports First-Quarter 2023 Results (Earnings Release Tables Attached)

Retrieved on: 
Friday, April 28, 2023

Excluding Linde AG purchase accounting impacts and other charges, adjusted net income was $1,693 million, up 13% versus prior year.

Key Points: 
  • Excluding Linde AG purchase accounting impacts and other charges, adjusted net income was $1,693 million, up 13% versus prior year.
  • Linde’s sales for the first quarter were $8,193 million, flat versus prior year or 3% above when excluding negative currency impact.
  • Linde Engineering sales were $540 million, 26% below prior year, and operating profit was $149 million or 27.6% of sales.
  • A teleconference on Linde’s first-quarter 2023 results is being held today at 9:00 am EST.

Nabors Industries Forms Strategic Alliance with Corva to Accelerate Digital Transformation of the Global Drilling Industry

Retrieved on: 
Thursday, April 20, 2023

Drilling engineers are inundated with redundant digital solutions and rig control systems to run automated well programs.

Key Points: 
  • Drilling engineers are inundated with redundant digital solutions and rig control systems to run automated well programs.
  • Together, Nabors and Corva seek to simplify the execution of automation on any AC rig.
  • Nabors' Digital and Automation Platform is Deployable on Any Rig, Regardless of Manufacturer
    SmartROS™ is the platform for the digitization and automation of drilling processes.
  • This creates an unparalleled ecosystem of digital and automation solutions that delivers consistent and repeatable results during the well construction process.

New Research Shows Companies Built for the Future Are Generating Shareholder Returns Almost Three Times Greater Than Those of the S&P 1200

Retrieved on: 
Tuesday, April 4, 2023

However, a few companies are built for the future, generating shareholder returns almost three times greater than those of the S&P 1200, with two-thirds of the value created coming from revenue growth.

Key Points: 
  • However, a few companies are built for the future, generating shareholder returns almost three times greater than those of the S&P 1200, with two-thirds of the value created coming from revenue growth.
  • For example:
    Advanced companies invest twice as much in AI solutions and realize 3.5 times greater return on investment.
  • "They also need to determine the minimum viable foundations of technology and data that will enable them to scale solutions.
  • Advanced companies are doing this and incorporating a continuous improvement agenda with new initiatives that leverage the progress they have already made."

At the Yacht Club de Monaco meetings and panels were held on the future of the yachting industry

Retrieved on: 
Friday, March 24, 2023

MONACO, March 24, 2023 (GLOBE NEWSWIRE) -- The first day of an intense week of initiatives comes to an end at the Yacht Club de Monaco, where meetings, discussions and panels dedicated to yachting and sustainability were held.

Key Points: 
  • MONACO, March 24, 2023 (GLOBE NEWSWIRE) -- The first day of an intense week of initiatives comes to an end at the Yacht Club de Monaco, where meetings, discussions and panels dedicated to yachting and sustainability were held.
  • Moreover the YCM is hosting the Monaco Smart Yacht Rendezvous.
  • “So many initiatives that are part of our collective approach ‘Monaco, Capital of Advanced Yachting’.
  • This is what we want to be: an innovation platform to support the yachting industry.

Foundation for Government Accountability Estimates Medicaid Enrollment to Surpass 100 Million in Early 2023

Retrieved on: 
Tuesday, December 20, 2022

NAPLES, Fla., Dec. 20, 2022 /PRNewswire-PRWeb/ -- Today, the Foundation for Government Accountability (FGA) projected the estimated number of Americans enrolled in Medicaid will surpass 100 million individuals in early 2023. This will be a record number of enrollees that includes 21 million ineligible individuals that earn too much to qualify for the welfare program.

Key Points: 
  • Nearly a Third of Americans Will Be on Medicaid, Regardless of Eligibility Requirements--An All-Time Record High
    NAPLES, Fla., Dec. 20, 2022 /PRNewswire-PRWeb/ -- Today, the Foundation for Government Accountability (FGA) projected the estimated number of Americans enrolled in Medicaid will surpass 100 million individuals in early 2023.
  • The dramatic rise in enrollment is largely due to the federal government's continued extension of the COVID-19 public health emergency.
  • While in effect, states receive extra Medicaid funding on the condition that everyone enrolled in Medicaid remain locked into the program.
  • The 100 million number is shocking—nearly a third of the country on government welfare," said Tarren Bragdon, President and CEO of FGA.

Atea Pharmaceuticals Announces First Patient Dosed in SUNRISE-3 Phase 3 Registrational Trial of Bemnifosbuvir, an Investigational Oral Antiviral for the Treatment of COVID-19

Retrieved on: 
Tuesday, November 29, 2022

BOSTON, Nov. 29, 2022 (GLOBE NEWSWIRE) -- Atea Pharmaceuticals, Inc. (Nasdaq: AVIR) (“Atea”), a clinical-stage biopharmaceutical company, today announced the enrollment of the first patient in the SUNRISE-3 Phase 3 trial, a global multicenter trial evaluating bemnifosbuvir (AT-527) for the treatment of COVID-19 in non-hospitalized patients at high risk for disease progression to hospitalization and death. The patient was enrolled and dosed at a U.S. clinical trial site. The study is designed to enroll at least 1,500 patients with mild or moderate COVID-19, and the primary endpoint is all-cause hospitalization or death through Day 29 in at least 1,300 patients in the monotherapy arm. Bemnifosbuvir is an investigational orally administered, direct-acting antiviral derived from Atea’s purine nucleotide prodrug platform.

Key Points: 
  • The patient was enrolled and dosed at a U.S. clinical trial site.
  • Bemnifosbuvir is an investigational orally administered, direct-acting antiviral derived from Ateas purine nucleotide prodrug platform.
  • New variants not susceptible to currently available preventive tools are driving COVID-19 infection waves, which should enable timely patient enrollment in SUNRISE-3.
  • Bemnifosbuvirs profile supports the potential for bemnifosbuvir to become a cornerstone monotherapy and combination oral therapy for the treatment of COVID-19.