Exonuclease

Under the Scanner: Gwangju Institute of Science and Technology Scientists Unravel the Inner Workings of DNA Repair Enzymes

Retrieved on: 
Tuesday, September 14, 2021
Gamma, Gwangju Institute of Science and Technology, Drug development, BER, Nucleobase, Protein, GIST, UV, Exonuclease, DNA repair, Korea, Reactive oxygen species, III, DNA, South Korea, Enzyme, AP, Research, Förster resonance energy transfer, Vaccine

Unravelling the DNA repair mechanism opens possibilities for cancer detection and targeted gene repair.

Key Points: 
  • Unravelling the DNA repair mechanism opens possibilities for cancer detection and targeted gene repair.
  • In such a scenario, a set of enzymes (proteins that act as catalysts for biochemical reactions) are activated to repair the damage.
  • The sequence of processes undertaken by the enzymes to fix DNA damage is known as "base excision repair" (BER).
  • "This study provides insights for investigation of operational mechanisms of other enzymes involved in DNA repair.