Erosion (morphology)

Travere Therapeutics Submits Supplemental New Drug Application to the U.S. Food and Drug Administration Seeking Full Approval of FILSPARI® (sparsentan) for the Treatment of IgA Nephropathy (IgAN)

Retrieved on: 
Monday, March 11, 2024
Angiotensin, SAN, European Commission, EMA, Erosion (morphology), Committee, New Drug Application, PROTECT, FDA, Food, Dialysis, Shanda, Hope, Risk, Civil service commission, Therapy, CHMP, CSL Vifor, EGFR, Patient, Immunoglobulin A, Kidney disease, Disease, Kidney, CMA, Proteinuria, Pharmaceutical industry

The sNDA is based on 2-year confirmatory results from the Phase 3 PROTECT Study, the only head-to-head study in IgAN versus an active comparator.

Key Points: 
  • The sNDA is based on 2-year confirmatory results from the Phase 3 PROTECT Study, the only head-to-head study in IgAN versus an active comparator.
  • “Since being introduced under accelerated approval, FILSPARI has positively impacted the lives of many people living with IgAN.
  • “FILSPARI is at the forefront of emerging new treatment options providing hope for a delay in kidney transplant or dialysis.
  • The FDA has 60 days from the receipt of the application to determine whether to accept it for review.

TKO Reports Full Year 2023 Results

Retrieved on: 
Tuesday, February 27, 2024
Entertainment, Sports, Other Entertainment, Other Sports, Wrestling, Martial Arts, Acquisition, TKO, Accounting, Forecasting, Free cash flow, Growth, UFC, Net income, Adjustment, Treasury, WWE SmackDown, GAAP, Information technology, Erosion (morphology), Public expenditure, WWE, Corporation, Ultimate, Depreciation, Bookkeeping

Adjusted EBITDA was $163.0 million for the period from September 12, 2023 through December 31, 2023.

Key Points: 
  • Adjusted EBITDA was $163.0 million for the period from September 12, 2023 through December 31, 2023.
  • Adjusted EBITDA margin was 43% for the period from September 12, 2023 through December 31, 2023.
  • Including WWE activity for the periods from January 1, 2023 through September 11, 2023 and for full year 2022, WWE combined Adjusted EBITDA margin3 was flat at 40% in both 2023 and 2022.
  • For the twelve months ended December 31, 2023, the Company’s consolidated pre-tax results included $83.8 million of merger and acquisition related costs.

TKO Reports Third Quarter 2023 Results

Retrieved on: 
Tuesday, November 7, 2023
Entertainment, Sports, Other Entertainment, Other Sports, Wrestling, Martial Arts, Adjustment, WWE, Public Sector Net Cash Requirement, Ultimate, Acquisition and Cross-Servicing Agreement, Public expenditure, EBITDA, Corporation, Treasury, GAAP, Free cash flow, Acquisition, Net income, UFC, Erosion (morphology), Information technology, Growth, TKO, Depreciation, Operation Active Endeavour, Accounting, Rare-earth element, Cryptocurrency, Bookkeeping, Real estate

Adjusted EBITDA margin was 43% for the period from September 12, 2023 through September 30, 2023.

Key Points: 
  • Adjusted EBITDA margin was 43% for the period from September 12, 2023 through September 30, 2023.
  • The dividend, which totaled approximately $321 million, was paid on September 29, 2023 to Class A common stockholders of record as of September 22, 2023.
  • As a result of the timing of the consummation of the business combination on September 12, 2023, TKO’s consolidated financial information presented herein include UFC’s results for the three and nine months ended September 30, 2023 and 2022, and only includes WWE’s results for the period from September 12, 2023 through September 30, 2023 following the closing of the transaction.
  • ET on November 7, 2023, to discuss its third quarter 2023 results.

HUMBL Announces a Multi-Year Memorabilia Partnership with Mixed Martial Artist Erin Blanchfield of the Ultimate Fighting Championship (UFC)

Retrieved on: 
Monday, October 16, 2023
Partnership, OTC, Sport, Female, Flyweight, UFC, Erosion (morphology), Ultimate, Social media, Athlete

San Diego, California, Oct. 16, 2023 (GLOBE NEWSWIRE) -- HUMBL, Inc. (OTC: HMBL) HUMBL announced today the launch of a two year sports memorabilia partnership with Erin Blanchfield, an American mixed martial artist currently competing in the Flyweight division of the Ultimate Fighting Championship (UFC).

Key Points: 
  • San Diego, California, Oct. 16, 2023 (GLOBE NEWSWIRE) -- HUMBL, Inc. (OTC: HMBL) HUMBL announced today the launch of a two year sports memorabilia partnership with Erin Blanchfield, an American mixed martial artist currently competing in the Flyweight division of the Ultimate Fighting Championship (UFC).
  • As a HUMBL Pro+ Social user, Erin has already started posting on her verified profile on www.HUMBL.com .
  • She will be featured on a HUMBL Chat Q+A session as well, using the company’s new HUMBL Chat video services.
  • The HUMBL Authentics portion of the partnership with Erin features autograph signings; as well as the right to make apparel with her likeness.

MMA Superstar Jorge “Gamebred” Masvidal Joins Safety Shot as Brand Ambassador

Retrieved on: 
Monday, October 16, 2023
UFC, Erosion (morphology), MMA, Safety, History, World Victory Road, Head, Ultimate, Fireworks

JUPITER, FL, Oct. 16, 2023 (GLOBE NEWSWIRE) -- Safety Shot, Inc. (Nasdaq: SHOT) today announced it has entered an agreement with mixed martial arts (MMA) superstar Jorge Masvidal who will serve as a brand ambassador for Safety Shot, the first patented beverage on Earth that helps people feel better faster by reducing blood alcohol content and boosting clarity.

Key Points: 
  • JUPITER, FL, Oct. 16, 2023 (GLOBE NEWSWIRE) -- Safety Shot, Inc. (Nasdaq: SHOT) today announced it has entered an agreement with mixed martial arts (MMA) superstar Jorge Masvidal who will serve as a brand ambassador for Safety Shot, the first patented beverage on Earth that helps people feel better faster by reducing blood alcohol content and boosting clarity.
  • Widely recognized as a superstar in the MMA community, Masvidal competed professionally for 20 years from 2003 to 2023.
  • Jorge Masvidal commented, “I’m proud to represent Safety Shot to our fans who follow me and Gamebred Bareknuckle.
  • He has earned the respect and admiration of millions and we welcome his support of Safety Shot,” stated Safety Shot’s CEO, Brian John.

Do 'sputnik moments' spur educational reform? A rhetoric scholar weighs in

Retrieved on: 
Tuesday, October 3, 2023
Civic, House, Risk, DARPA, Politics, National Commission on Excellence in Education, Soviet people, National security, National Academy of Educational Sciences of Ukraine, Speech, National Defense Education Act, Trump, National Commission, Language, Southern, Science, The Hastings Center, Erosion (morphology), School, Student, Democracy, National academy, Representative, Engineering, Sputnik 1, ICivics, A Nation at Risk, Mathematics, Union, Pioneer High School, Legislation, Communications satellite, Management, Nursing, Renewable energy, Life, USSR, American, Education

From the publication of the landmark A Nation at Risk report on education in 1983 to the polarizing election of Donald Trump, one moment after another has been compared to the sputnik episode.

Key Points: 
  • From the publication of the landmark A Nation at Risk report on education in 1983 to the polarizing election of Donald Trump, one moment after another has been compared to the sputnik episode.
  • As a professor who studies the rhetoric of education reform, I know that what politicians and others call sputnik moments do not always live up to that name.
  • Some sputnik moments spark enduring public debates, while others are easily forgotten.

American education called into question

    • In the spring of 1958, Life magazine ran a series of articles entitled: “Crisis in Education.” One Life article compared the rigor of U.S. education unfavorably with that of the Soviets.
    • Another Life article referred to American education as a “carnival.” President Dwight Eisenhower read the Life articles and began advocating for what would become the National Defense Education Act of 1958.
    • It was a first-of-its-kind intervention in education policy and funding.
    • Ever since, pivotal events for education in the U.S. have been called sputnik moments.

Reagan and a flailing education system

    • In 1983, the National Commission on Excellence in Education published A Nation at Risk.
    • We responded by making math, science, and engineering education a priority.” Reagan cited NASA’s space shuttle program as evidence that the nation had succeeded.
    • But like sputnik, it spurred decades of discussion about the rigor of public education in the U.S.

Obama on competition with China

    • Obama needed to sell his proposal to the nation and to the House of Representatives, which the Republicans had taken control of in the 2010 midterm elections.
    • It also did not result in the creation of an Advanced Research Projects Agency for education.

Donald Trump’s election

    • Sure enough, Trump’s election did revitalize the national discussion of civic education.
    • There was also the Civic Learning for a Democracy in Crisis by the Hastings Center.
    • Even the Trump administration joined in the conversation with its 1776 report, which called for a patriotic form of civic education.

Why do we have sputnik moments?

    • Sputnik moments can be spontaneous or constructed through rhetoric after the fact, or they can fall somewhere in between.
    • In the late 1950s, critics of American education made the most of their moment by demanding a greater emphasis on math, science and language.
    • Because they capitalized on their moment, policymakers and education reformers have continued to be vigilant for more moments like sputnik ever since.

NovaBay Pharmaceuticals to Present at the Dawson James Small Cap Growth Conference

Retrieved on: 
Monday, October 2, 2023
Research, Other Health, General Health, Family, Pharmaceutical, Optical, Consumer, Science, Biotechnology, Women, Medical Supplies, Health, Other Science, General counsel, NBY, NovaBay Pharmaceuticals, LHA, Erosion (morphology), Justin Hall, Conference, NYSE

NovaBay Pharmaceuticals, Inc. (NYSE American: NBY), a company developing and commercializing high-quality eyecare, skincare and wound care products, announces that Justin Hall, CEO and General Counsel, will present a company overview and hold investor meetings at the 8th Annual Dawson James Small Cap Growth Conference being held Thursday, October 12, 2023 at the Wyndham Grand Harborside Hotel in Jupiter, Fla.

Key Points: 
  • NovaBay Pharmaceuticals, Inc. (NYSE American: NBY), a company developing and commercializing high-quality eyecare, skincare and wound care products, announces that Justin Hall, CEO and General Counsel, will present a company overview and hold investor meetings at the 8th Annual Dawson James Small Cap Growth Conference being held Thursday, October 12, 2023 at the Wyndham Grand Harborside Hotel in Jupiter, Fla.
    “We are excited to showcase the innovative products in our eyecare, skincare, and wound care business segments at this upcoming conference,” said Mr. Hall.
  • “I’ll be presenting our future strategies to address the large market opportunities for the Avenova ®, DERMAdoctor ® and PhaseOne ® brands.”
    Investors interested in arranging a meeting with NovaBay management should contact Jody Cain at LHA Investor Relations.
  • The NovaBay corporate presentation can be access from the Presentation page of the Investor Relations section of the Company’s website.

Panavance Therapeutics Announces Publication of Encouraging Preclinical Data Evaluating GP-2250 for the Treatment of Merkel Cell Carcinoma (MCC)

Retrieved on: 
Thursday, June 29, 2023
Survival rate, STAT3, University, Glomus tumor, Bromodeoxyuridine, Merkel cell polyomavirus, Necrosis, Journal of Cancer Research and Clinical Oncology, Skin cancer, Quality of life, Ruhr University Bochum, University of Duisburg-Essen, AKT, Patient, Manuscript, Cancer, Flow cytometry, MCC, Apoptosis, MTT, Organ (biology), ST, Pharmaceutical industry, Vaccine, Panaveli, Angela Merkel, Erosion (morphology)

BERWYN, Pa., June 29, 2023 (GLOBE NEWSWIRE) -- Panavance Therapeutics Inc. (“Panavance” or the “Company”), a clinical-stage pharmaceutical company advancing the development of a novel oncology therapeutic intended to improve the effectiveness of cancer treatments and quality of life for the patients that receive them, today announced the publication of positive preliminary data in a manuscript titled, “The effect of GP‑2250 on cultured virus‑negative Merkel cell carcinoma cells: preliminary results1,” in the peer-reviewed Journal of Cancer Research and Clinical Oncology.

Key Points: 
  • The objective of the preclinical study was to investigate the effects of GP-2250 on Merkel cell polyomavirus (MCPyV)-negative MCC cells.
  • Greg Bosch, Chairman and CEO of Panavance Therapeutics commented, “We are encouraged by these preclinical findings in this rare, aggressive form of skin cancer.
  • This study was able to show that GP-2250 has significant, dose-dependent cytotoxic effects on MCC cells as well as reduced cancer cell proliferation and migration.
  • GP-2250’s effects on cell viability, proliferation and migration were evaluated by means of MTT, BrdU, and scratch assays, respectively.

Distinction Agency Hosting Creator Summit in Las Vegas

Retrieved on: 
Monday, June 26, 2023
Lemmons, Miami Dolphins, UFC, Erosion (morphology), Saks, Q&A, HuffPost, Menace, Ffrench, Athlete, Saks Fifth Avenue, Publication, Agency, NBA, Aria Resort and Casino, Distinction, Sport, Entrepreneurship, Ultimate, AI, Lightweight, Hype, Puma, Creative industries

LAS VEGAS, June 26, 2023 /PRNewswire/ -- Distinction Agency, an award-winning marketing agency that works with athletes, brands, content creators and sports properties, announced today they are hosting a Creator Summit on July 8, 2023 from 12:30 PM-3:00 PM at the ARIA Resort & Casino in Las Vegas, NV.

Key Points: 
  • LAS VEGAS, June 26, 2023 /PRNewswire/ -- Distinction Agency, an award-winning marketing agency that works with athletes, brands, content creators and sports properties, announced today they are hosting a Creator Summit on July 8, 2023 from 12:30 PM-3:00 PM at the ARIA Resort & Casino in Las Vegas, NV.
  • Distinction Agency's Creator Summit will feature influential content creators, entrepreneurs and professional athletes.
  • Distinction Agency's Creator Summit will feature influential content creators, entrepreneurs and professional athletes.
  • Programming will provide attendees with the blueprint they need to be successful in the sports and entertainment industry through panel discussions, Q&A and intimate networking.

PhaseOne Health Collaborates with Nonprofit Humanitarian Organization to Supply NovaBay Pharmaceuticals’ Phase One® Skin and Wound Cleanser to Ukraine

Retrieved on: 
Friday, May 5, 2023
Philanthropy, Retail, Health, Other Philanthropy, Specialty, Pharmaceutical, Biotechnology, Partnership, Hypochlorous acid, NBY, NovaBay Pharmaceuticals, Erosion (morphology), Ulcer, Burns, NYSE, Skin, Injury, Cosmetics

PhaseOne Health announces it has provided PhaseOne Skin and Wound Cleanser (PhaseOne) as part of a $3 million donation of medical supplies to Ukraine in partnership with the nonprofit HelpingUkraine.us .

Key Points: 
  • PhaseOne Health announces it has provided PhaseOne Skin and Wound Cleanser (PhaseOne) as part of a $3 million donation of medical supplies to Ukraine in partnership with the nonprofit HelpingUkraine.us .
  • PhaseOne is distributed in the U.S. by PhaseOne Health.
  • It is non-toxic, non-irritating and non-sensitizing to skin and new tissue and can be used on wounds as frequently as needed.
  • Through our proprietary manufacturing process and amber glass bottle, we ensure the safest, purest, most powerful hypochlorous acid wound cleanser on the market.”