London

Nordea Bank Abp: Flagging notification in accordance with Chapter 9, Section 10 of the Securities Markets Act

Wednesday, December 2, 2020 - 11:05am

The information provided in this stock exchange release was submitted for publication, through the agency of the contact persons set out above, at 11.45 EET on 2 December 2020.

Key Points: 
  • The information provided in this stock exchange release was submitted for publication, through the agency of the contact persons set out above, at 11.45 EET on 2 December 2020.
  • This information is provided by RNS, the news service of the London Stock Exchange.
  • RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom.
  • Terms and conditions relating to the use and distribution of this information may apply.

Sio Gene Therapies Announces First Patient Dosed in High-Dose Cohort of AXO-AAV-GM1 Clinical Trial in Patients with GM1 Gangliosidosis

Wednesday, December 2, 2020 - 12:00pm

AXO-AAV-GM1 is the only gene therapy in the clinic targeting patients with Type I and Type II GM1 gangliosidosis, a devastating and fatal pediatric disease, said Gavin Corcoran, M.D., Chief R&D Officer of Sio.

Key Points: 
  • AXO-AAV-GM1 is the only gene therapy in the clinic targeting patients with Type I and Type II GM1 gangliosidosis, a devastating and fatal pediatric disease, said Gavin Corcoran, M.D., Chief R&D Officer of Sio.
  • The Phase 1/2 study ( NCT03952637 ) is designed to evaluate the safety, tolerability, and potential efficacy of AXO-AAV-GM1 delivered intravenously in patients with Type I and Type II GM1 gangliosidosis.
  • The low-dose cohort evaluated 1.5x1013 vg/kg AXO-AAV-GM1 gene therapy in a total of five Type II (juvenile) patients.
  • Sio Gene Therapies combines cutting-edge science with bold imagination to develop genetic medicines that aim to radically improve the lives of patients.

FPT Industrial and Slow Food support sustainable food production communities

Wednesday, December 2, 2020 - 11:00am

The two communities jointly selected by FPT Industrial and Slow Food are the cooperatives Valdibella and NoE in Sicily, Italy and La Seyne-sur-Mer Prudhomie in southern France.

Key Points: 
  • The two communities jointly selected by FPT Industrial and Slow Food are the cooperatives Valdibella and NoE in Sicily, Italy and La Seyne-sur-Mer Prudhomie in southern France.
  • FPT Industrial and Slow Food will support the two cooperatives in their projects which are focused on the creation of a food forest reproducing the natural eco-system and capable of diversifying food production while preserving the landscape, as well as the creation of an autonomous supply chain model, to deliver high quality biological food at an affordable price.
  • With the support of FPT Industrial and Slow Food, the community will be able to upgrade its infrastructure as well as create additional local jobs.
  • Slow Food believes food is tied to many other aspects of life, including culture, politics, agriculture and the environment, commented Francesco Sottile of Slow Food.

CNH Industrial announces the closing of its notes offering of Euro 750,000,000 guaranteed 0.000% notes due April 2024

Tuesday, December 1, 2020 - 4:45pm

The notes have been issued by CNH Industrial Finance Europe S.A., a wholly-owned subsidiary of CNH Industrial N.V., under the Euro Medium Term Note Programme guaranteed by CNH Industrial N.V. CNH Industrial Finance Europe S.A. intends to use the net proceeds from the offering for its general corporate purposes including repayment of existing debt.

Key Points: 
  • The notes have been issued by CNH Industrial Finance Europe S.A., a wholly-owned subsidiary of CNH Industrial N.V., under the Euro Medium Term Note Programme guaranteed by CNH Industrial N.V. CNH Industrial Finance Europe S.A. intends to use the net proceeds from the offering for its general corporate purposes including repayment of existing debt.
  • The notes have been admitted to listing on the Irish Stock Exchange.
  • No action has been or will be taken to permit a public offering of the notes in any jurisdiction.
  • The offering of the notes has not been cleared by the Commissione Nazionale per le Societ e la Borsa (CONSOB), pursuant to Italian securities legislation.

VivoPower International PLC Announces Successful Refinancing for its Wholly-Owned Subsidiaries in Australia

Tuesday, December 1, 2020 - 2:23pm

LONDON, Dec. 01, 2020 (GLOBE NEWSWIRE) -- VivoPower International PLC (NASDAQ: VVPR, the Company), is pleased to announce that its wholly-owned subsidiaries in Australia, J.A.

Key Points: 
  • LONDON, Dec. 01, 2020 (GLOBE NEWSWIRE) -- VivoPower International PLC (NASDAQ: VVPR, the Company), is pleased to announce that its wholly-owned subsidiaries in Australia, J.A.
  • Martin) and Kenshaw Electrical Pty Limited (Kenshaw), have successfully completed a refinancing of their funding facilities.
  • Executive Chairman and CEO of VivoPower, Kevin Chin, commented, Over the past 2 years, funding constraints and costs have hampered the ability for J.A.
  • VivoPower is a certified B Corporation and has operations in Australia, Canada, the United States and the United Kingdom.

BoxVn Closes Key, Accretive Logistics Acquisition

Tuesday, December 1, 2020 - 2:19pm

By integrating Hitras strengths and capabilities, this deal catapults BoxVn into a key player in the critical, logistics industry.

Key Points: 
  • By integrating Hitras strengths and capabilities, this deal catapults BoxVn into a key player in the critical, logistics industry.
  • Management and fleet teams will integrate long distance, two-man, white glove, and multi-drop routes into the BoxVn Framework.
  • The acquisition immediately expands our offerings, could add $1,000,000 in revenue in 2021 and be accretive to BoxVn earnings.
  • James Gilzean, CEO of BoxVn, said, We are delighted to welcome the Hitra team into the BoxVn family.

Telefónica Movistar Chile Partners with Amdocs to Extend and Expand Multi-Year Managed Services Agreement and Launch Innovative eSIM Service

Tuesday, December 1, 2020 - 11:00am

This is happening with Telefnica Movistar Chiles launch of Amdocs cloud-based, digital eSIM management solution that builds on .

Key Points: 
  • This is happening with Telefnica Movistar Chiles launch of Amdocs cloud-based, digital eSIM management solution that builds on .
  • Telefnica Movistar Chile has re-affirmed its relationship with Amdocs by signing a multi-year agreement for extension of existing managed services and expanding to now also include copper-based wireline services.
  • As a result, the Amdocs-based digital platform will extend its support to Telefnica Movistar Chiles wireless and wireline services (FTTx/IPTV /FWT/LTE/copper) for all of its B2C and B2B customers.
  • Amdocs SaaS-based eSIM platform is pre-integrated with leading eSIM device manufacturers, providing simple and intuitive eSIM activation and digital lifecycle management while lowering TCO.

Amdocs Once Again Named to Dow Jones Sustainability Index (DJSI) for North America

Tuesday, December 1, 2020 - 11:00am

The Dow Jones Sustainability Indices ("DJSI") are considered among the most important global indicators of sustainability leadership, evaluating public companies on environmental, social and governance (ESG) factors relevant to their industry.

Key Points: 
  • The Dow Jones Sustainability Indices ("DJSI") are considered among the most important global indicators of sustainability leadership, evaluating public companies on environmental, social and governance (ESG) factors relevant to their industry.
  • The Dow Jones Sustainability North America Index represents the top 20% of the largest 600 North American companies in the S&P Global Broad Market Index (BMI) based on long-term economic, environmental and social criteria.
  • The index is used as a reference by shareholders who consider sustainability when making investment decisions.
  • We congratulate Amdocs for being included in the DJSI North America.

Tiziana Life Sciences to Host Investor Update Call on 2 December 2020 at 4:15 p.m. ET

Tuesday, December 1, 2020 - 7:00am

Tiziana Life Sciences plc is a UK biotechnology company that focuses on the discovery and development of novel molecules to treat human disease in oncology and immunology.

Key Points: 
  • Tiziana Life Sciences plc is a UK biotechnology company that focuses on the discovery and development of novel molecules to treat human disease in oncology and immunology.
  • In addition to Milciclib, the Company is also developing Foralumab for liver diseases.
  • Foralumab is the only fully human anti-CD3 monoclonal antibody in clinical development in the world.
  • The company is accelerating development of anti-Interleukin 6 receptor (IL6R) mAb, a fully human monoclonal antibody for treatment of IL6-induced inflammation, especially for treatment of COVID-19 patients.

Autolus Therapeutics announces publication of new AUTO6 Phase 1 data in childhood neuroblastoma in Science Translational Medicine

Monday, November 30, 2020 - 12:00pm

CAR T cell expansion was observed in all six patients treated at the higher cell dose cohorts in this Phase 1 study.

Key Points: 
  • CAR T cell expansion was observed in all six patients treated at the higher cell dose cohorts in this Phase 1 study.
  • This is of particular importance as this activity was observed in the absence of neurotoxicity which occurs with antibody-based approaches that target GD2.
  • We look forward to seeing the next steps in the development of AUTO6NG, and if the treatment has durable effects in neuroblastoma.
  • AUTO6NG builds on preliminary proof of concept data from AUTO6, a CAR targeting GD2-expression cancer cell currently in clinical development for the treatment of neuroblastoma.