EASE

Escient Pharmaceuticals Initiates Clinical Proof-of-Concept Study of EP262, a First-in-Class Oral MRGPRX2 Antagonist, in Atopic Dermatitis

Retrieved on: 
Tuesday, November 28, 2023
Health, Neurology, Clinical Trials, Research, Science, Pharmaceutical, Biotechnology, Safety, B cell, American Academy, Dermatitis, Patient, Atopic dermatitis, Therapy, American Academy of Dermatology, MRGPRX2, IL4, Escient, Skin, Pharmaceutical industry, EASE, Dermatology

By blocking activation of MRGPRX2 and degranulation of mast cells, EP262 has the potential to effectively treat multiple mast cell mediated diseases with an initial focus on chronic urticaria (hives) and atopic dermatitis (eczema).

Key Points: 
  • By blocking activation of MRGPRX2 and degranulation of mast cells, EP262 has the potential to effectively treat multiple mast cell mediated diseases with an initial focus on chronic urticaria (hives) and atopic dermatitis (eczema).
  • EP262 represents a novel, targeted approach to the treatment of these disorders with the potential for once-daily oral administration without the side effects observed with other approaches.
  • The study will evaluate clinical scores as well as histological and transcriptomic markers in lesional skin biopsies.
  • “With the initiation of our EASE clinical proof-of-concept study, we look forward to evaluating whether the promising preclinical findings with EP262 translate to patients with atopic dermatitis,” said Christian Weyer, M.D., M.A.S, Chief Medical Officer at Escient.

AlgoTx Announces First Patients Dosed in US and European Arms of Phase II Clinical Trial of ATX01 in Rare Disease Erythromelalgia

Retrieved on: 
Tuesday, September 12, 2023
ACT, Crossover study, Mayo, Chemotherapy-induced peripheral neuropathy, Extremities, Therapy, Face, Safety, Efficacy, Quality of life, Toxicity, Research, CIPN, EMA, Pain, Dermatology, Erythema, Patient, Swelling, EASE, FDA, Skin temperature, Peripheral nervous system, Pharmaceutical industry, Dentistry, Erythromelalgia

Under Orphan Drug Designation from FDA and EMA, this trial investigates the efficacy of the company’s lead asset ATX01 on the pain of Erythromelalgia, a rare neurological and vascular disease characterized by painful extremities for which there is no available treatment.

Key Points: 
  • Under Orphan Drug Designation from FDA and EMA, this trial investigates the efficacy of the company’s lead asset ATX01 on the pain of Erythromelalgia, a rare neurological and vascular disease characterized by painful extremities for which there is no available treatment.
  • I am delighted to be leading the European part of the phase II clinical trial of ATX01.”
    The Mayo Clinic’s Julio Sartori Valinotti MD is involved in the research in the U.S.
  • This condition primarily affects the feet, and less commonly, the hands, arms, legs, ears, and face.
  • It is characterized by intense, burning pain, increases in skin temperature, swelling and severe redness (erythema) of the affected extremities.

Introducing the Initial 2024 Sponsor Line Up for Manifest Vegas

Retrieved on: 
Thursday, June 22, 2023
Ryder, Heart, Coffeehouse, ArcBest, Lyase, DHL Supply Chain, BrightDrop, DHL, Expo Hall, DB Schenker, Vizion Plus, Caesars Forum, Manifest, Lunch, EASE, Coffee, Datamatics, Video game, Maersk, Expo, Flexport

NEW YORK, June 22, 2023 /PRNewswire-PRWeb/ -- The hold that Manifest Vegas currently has on the global logistics & end-to-end supply chain ecosystems would not have been possible without its valued sponsors. The team is honored to share the innovative companies that have already committed to support the 2024 event, with DHL Supply Chain returning as lead sponsor!

Key Points: 
  • NEW YORK, June 22, 2023 /PRNewswire-PRWeb/ -- The hold that Manifest Vegas currently has on the global logistics & end-to-end supply chain ecosystems would not have been possible without its valued sponsors.
  • The team is honored to share the innovative companies that have already committed to support the 2024 event, with DHL Supply Chain returning as lead sponsor!
  • "We are thrilled to return as headline sponsors for the Manifest 2024 conference," said Sally Miller, Chief Information Officer, DHL Supply Chain.
  • An engaging and non-traditional trade show experience has become synonymous with Manifest Vegas, and 2024 will not disappoint!

Becknell Industrial Signs Lease with EASE Logistics in Marysville, Ohio

Retrieved on: 
Wednesday, June 21, 2023
Partnership, City manager, Food, SIOR, SF, CCIM, City, Innovation Park, EASE, Growth, William Becknell, Warehouse, Development

INDIANAPOLIS, June 21, 2023 (GLOBE NEWSWIRE) -- Becknell Industrial is pleased to announce the signing of a 308,358 SF lease with EASE Logistics, a full-service logistics company providing services across dozens of industries including automotive, manufacturing, food and beverage, and government sectors.

Key Points: 
  • INDIANAPOLIS, June 21, 2023 (GLOBE NEWSWIRE) -- Becknell Industrial is pleased to announce the signing of a 308,358 SF lease with EASE Logistics, a full-service logistics company providing services across dozens of industries including automotive, manufacturing, food and beverage, and government sectors.
  • The facility will be located on an approximately 25-acre site at the 33 Innovation Park in Marysville, Ohio.
  • Becknell’s Senior Vice President of Development, Derek Hawkins, said, “Becknell is excited to be working with EASE on this facility to accommodate their incredible growth.
  • This project has been a highly collaborative effort between EASE and Becknell, which is a testament to Becknell’s vertically integrated platform.

EASE LOGISTICS IS FIRST IN U.S. TO DEPLOY AUTOMATED TRUCKING TECHNOLOGY ON REVENUE-GENERATING ROUTES

Retrieved on: 
Wednesday, May 17, 2023
Acceleration, ODOT, U.S. Department of Defense Strategy for Operating in Cyberspace, ADS, Business operations, Ohio Department of Transportation, A.I, Rural area, Federal Motor Carrier Safety Administration, Movement, Transportation Research Center, TRC, Weather, DriveOhio, Safety, Renewable energy, Road, Rail transport, Online shopping, Transport, EASE

Columbus, Ohio-based EASE Logistics is the first in the U.S. to deploy automated trucking on revenue-generating roads.

Key Points: 
  • Columbus, Ohio-based EASE Logistics is the first in the U.S. to deploy automated trucking on revenue-generating roads.
  • As the chosen host fleet partner for the Ohio Department of Transportation (ODOT) and DriveOhio's Rural Automated Driving Systems (ADS) project, EASE will soon be the first in the U.S. to deploy connected and automated trucking technology on revenue-generating routes.
  • "EASE is honored to be the first in the U.S. to deploy these vehicles on revenue-generating routes," says Abbi Failla, EASE VP of Business Operations.
  • "Our goal is to develop, pilot, and deploy new smart technology initiatives to ensure that Ohio is the leading state in smart mobility innovation."

AAFC Launches EASE® Healthcare Program in Ghana With FOCOS Orthopedic Hospital

Retrieved on: 
Thursday, May 11, 2023
Medical Supplies, Medical Devices, Health, Hospitals, Physical Therapy, Managed Care, Maintenance, CT, Business development, Menzgold Ghana Limited, Senior, Health care, Organization, Siemens Healthineers, Patient, EASE, AAFC, Growth, Medical imaging, Hospital, Nursing

The contract, which marks the launch of the EASE® Healthcare program in Ghana, will see the installation of a Siemens CT scanner in the Accra facility of FOCOS Orthopedic Hospital.

Key Points: 
  • The contract, which marks the launch of the EASE® Healthcare program in Ghana, will see the installation of a Siemens CT scanner in the Accra facility of FOCOS Orthopedic Hospital.
  • “We are thrilled to announce this deal to bring a new, best-in-class CT scanner to one of Ghana’s leading healthcare providers,” said Kanyinsola Oyeyinka, AAFC’s VP Healthcare, Africa, responsible for AAFC’s EASE® Healthcare program across the continent.
  • Dr Wulff, CEO of FOCOS Hospital commented: “With EASE, we're able to access first-rate diagnostic equipment for the hospital.
  • EASE® Ghana will upgrade FOCOS Hospital’s existing, non-functioning CT scanner with a new and upgraded CT from Siemens Healthineers (Somatom Go.

EASE Logistics is Top in Transportation on Fortune's Inaugural List of America's Most Innovative Companies

Retrieved on: 
Friday, April 21, 2023
Allegiant Travel Company, FedEx, Overalls, COVID-19, Centre for Process Innovation, Delta Air Lines, Innovation, LATAM Airlines Group, UPS, EASE, Statista, Transport, American Airlines Group, DriveOhio, Safety, Automation, Management, Warehouse, Telescopic sight

DUBLIN, Ohio, April 21, 2023 /PRNewswire/ -- EASE Logistics has been named one of America's Most Innovative Companies, ranking #143 on Fortune's list of U.S. companies transforming industries from the inside out.

Key Points: 
  • DUBLIN, Ohio, April 21, 2023 /PRNewswire/ -- EASE Logistics has been named one of America's Most Innovative Companies, ranking #143 on Fortune's list of U.S. companies transforming industries from the inside out.
  • EASE notably came in first in the transportation category, above Delta Air Lines, FedEx, American Airlines Group, Allegiant Travel Company, and UPS.
  • EASE Logistics named one of America's Most Innovative Companies by Fortune, ranking #143 overall & #1 in transportation.
  • EASE's unique commitment to an innovative culture has yielded extraordinary results that are driving transformation in the logistics industry.

AlgoTx Progresses ATX01 in Two Indications

Retrieved on: 
Thursday, March 30, 2023
Biotechnology, FDA, Health, Clinical Trials, Oncology, ACT, Exercise, Erythromelalgia, Mayo Clinic, EU, Spinal cord, University of Erlangen–Nuremberg, Skin, Hope, Brain, CIPN, EMA, Pain, Nav1.7, Patient, Swelling, EASE, Clinical professor, Regulation of food and dietary supplements by the U.S. Food and Drug Administration, IND, Red, Food, Nav1.8, Peripheral nervous system, Pharmaceutical industry

Meanwhile, the first patients have been randomized into the “ATX01 for the pain of ChemoTherapy” (ACT) study in Chemotherapy-Induced Peripheral Neuropathy (CIPN).

Key Points: 
  • Meanwhile, the first patients have been randomized into the “ATX01 for the pain of ChemoTherapy” (ACT) study in Chemotherapy-Induced Peripheral Neuropathy (CIPN).
  • Both programs have been granted Fast Track Designation by the FDA.
  • AlgoTx is conducting the ACT study as part of its US / EU Phase 2 program in the indication of CIPN.
  • AlgoTx has obtained an Orphan Disease Designation from both FDA and EMA to support development of ATX01 in this indication.

SMA Technologies and Jack Henry Collaborate to Improve Operational Efficiencies for Banks & Credit Unions

Retrieved on: 
Tuesday, March 14, 2023
CCI (ammunition), Senior, SMA, API, Silver, EASE, Symitar, Automation, Information technology, Management

SMA Technologies will help banks using Jack Henry's SilverLake data center to automate and orchestrate workflows with other applications, data, and processes the institutions manage on-premises.

Key Points: 
  • SMA Technologies will help banks using Jack Henry's SilverLake data center to automate and orchestrate workflows with other applications, data, and processes the institutions manage on-premises.
  • According to a recent Jack Henry study , 44 percent of financial institution CEOs ranked operating efficiency as the most important strategic priority, with automation being a key component.
  • SMA Technologies CEO Todd Dauchy added, "Expanding our relationship with Jack Henry will increase operational efficiencies for credit unions and banks across America so they can invest time and energy where it matters most: accountholder experience.
  • This additional collaboration allows API connectivity to streamline the workflow management between financial institutions and Jack Henry data centers.

Luminate Capital Partners Makes Strategic Growth Investment in Ease, Inc.

Retrieved on: 
Tuesday, March 7, 2023
Electronics, SAN, Lincoln International, Kirkland & Ellis, Spotlight, Ease, Growth, Partner (business rank), Software as a service, Risk, Entrepreneurship, EASE, ROI, McDermott Will & Emery, Safety, Online shopping, Luminate

SAN CLEMENTE, Calif. and SAN FRANCISCO, March 7, 2023 /PRNewswire/ -- Luminate Capital Partners, a private equity firm focused on enterprise software, today announced a majority-stake growth investment in Ease, Inc. ("Ease"), a leader in manufacturing plant floor audit software.

Key Points: 
  • SAN CLEMENTE, Calif. and SAN FRANCISCO, March 7, 2023 /PRNewswire/ -- Luminate Capital Partners, a private equity firm focused on enterprise software, today announced a majority-stake growth investment in Ease, Inc. ("Ease"), a leader in manufacturing plant floor audit software.
  • Luminate's investment will help Ease expand its leadership position in the manufacturing software sector by accelerating new product development, innovation, and other key growth initiatives.
  • "Ease has seen impressive growth in recent years," added Chris Murphy, Operating Partner at Luminate.
  • In connection with the investment, Hollie Haynes, Chris Murphy, and Dave Ulrich will join Eric Stoop on Ease's Board of Directors.