ACS Omega

Abstrax Discovers New Exotic Flavor Compounds and Cannabis’ Hidden Flavor Spectrum: Beyond Terpenes to a World of Sweet, Savory, Citrus, and Fruity Flavorants

Retrieved on: 
Thursday, October 12, 2023
Research, Cannabis, Tobacco, Specialty, Agriculture, Natural Resources, Retail, Science, Chemicals, Plastics, Alternative Medicine, Health, Other Science, Manufacturing, Candy, Multimedia, T. J. Martin, Doctor of Philosophy, ACS Omega, Markes International, Kentville Research and Development Centre, Skatole, Tangie, VSC, DIM, Labs, Genetics, CB2, Classification, Alcohol, Entrepreneurship, Terpene, Love, CB1, Chemistry, GMO, Citrus, Chemical substance, ACS, Compound, Ketone, Ester, Schematic, Perfume, Aroma compound, Medicinal plants, Drug, Indole, Chem

Higher numbers indicate the variety was ranked to be sweet or fruity, while lower numbers indicate the varieties were ranked as not sweet or fruity.

Key Points: 
  • Higher numbers indicate the variety was ranked to be sweet or fruity, while lower numbers indicate the varieties were ranked as not sweet or fruity.
  • The numbers do not correspond to aroma quality - meaning a higher number is not better than a lower number.
  • The results revealed pronounced differences between varieties , with some described as "sweet or fruity" and others as "savory or chemical."
  • Abstrax scientists highlight two classes, including tropical Volatile Sulfur Compounds (VSCs) and the heterocyclic compounds Indole and Skatole.

RespireRx Pharmaceuticals Inc. Discloses Novel Structural Analogs of its GABAA Receptor Potentiator, KRM-II-81 with Antiseizure Efficacy and Antitremor Effects without Sedation.

Retrieved on: 
Monday, April 3, 2023
Epilepsy, GABA, Anticonvulsant, Tremor, GABAergic, OTC Markets Group, DRS, KPP, University of Wisconsin–Milwaukee, KRM, Essential tremor, Pain, Patient, University, Blood, Neuropathic pain, Indiana University–Purdue University Indianapolis, Irena Kosmowska, Drug discovery, CFO, ACS Omega, IND, RespireRx, Pharmaceutical industry

Like KRM-II-81, these analogs enhance GABAergic neurotransmission and function as orally-bioavailable anti-seizure agents in the absence of the sedation typically associated with GABA augmentation.

Key Points: 
  • Like KRM-II-81, these analogs enhance GABAergic neurotransmission and function as orally-bioavailable anti-seizure agents in the absence of the sedation typically associated with GABA augmentation.
  • In addition KRM-II-81 is active in relieving acute, chronic, and neuropathic pain in a number of models without developing tolerance or producing sedation.
  • 385:50-61 document the preclinical effects and tolerability of structural analogs of KRM-II-81.
  • In established rat models predicting efficacy in essential tremor and in tremor associated with Parkinson’s Disease, MP-III-024 was an effective anti-tremor compound.

Usona Identifies Controlled Crystal Engineering Process for Large-Scale Synthesis of Psilocybin Polymorphs

Retrieved on: 
Monday, February 7, 2022
Biotechnology, Alternative Medicine, FDA, Other Health, Health, Pharmaceutical, Mental Health, Other Science, Research, Science, Clinical Trials, Psilocybin, Depression, Particle size, PSD, Anxiety, Oxide, Multimedia, Quality of life, MRO, API, Chemistry (relationship), Temperature, Paper, ACS Omega, Aluminium, Pharmaceutical industry, Religion in North America

New research by Usona Institute identifies the most favorable environments to achieve consistency and reproducibility of pharmaceutical psilocybin produced at large scale.

Key Points: 
  • New research by Usona Institute identifies the most favorable environments to achieve consistency and reproducibility of pharmaceutical psilocybin produced at large scale.
  • Applying these findings, the paper details the formation of three psilocybin polymorphs: polymorph B (trihydrate), polymorph A (anhydrate), and polymorph H (anhydrate).
  • Usona chemists designed a thermodynamically controlled crystal engineering process using measurement of the metastable zone width (MSZW) and nucleation induction to produce a unique crystalized form of psilocybin with stronger interactions, controlled particle size distribution (PSD), and improved impurity profile.
  • The process required controlled drying time and the thin spread of active pharmaceutical ingredient (API) during the drying process.

Alcon Canada Announces Launch of TOTAL30® as the First-and-Only Monthly Replacement, Water Gradient Contact Lens

Retrieved on: 
Tuesday, February 1, 2022
Eye, Optometry, Patient, Water, Veni, vidi, vici, Trial of the century, American Academy, CLEAR, 3D, Technology, Cornea, Bacteria, Instagram, TOTAL, Ophthalmology, Approximation error, Retina, Glaucoma, Lecture, Cataract, Quality of life, Conference, Lens, ACS Omega, Mark (given name), Lens (anatomy), Telescopic sight, Camera, Medical device, Microscope, Alcon, Facebook

TOTAL30 delivers a reusable lens with a Water Gradient surface that remains durable for a full 30 days, helping Canadians see brilliantly."

Key Points: 
  • TOTAL30 delivers a reusable lens with a Water Gradient surface that remains durable for a full 30 days, helping Canadians see brilliantly."
  • Patients often feel that discomfort is a normal and unavoidable part of the monthly replacement contact lens wearing experience.
  • The reusable, Water Gradient design of TOTAL30 is made possible by the introduction of new biomimetic CELLIGENT Technology.
  • Surface observations of lehfilcon A contact lens and human cornea using scanning transmissions electron microscopy; Alcon data on file, 2020.

ABSTRAX Pins the Exact Origin of Cannabis' Distinctive Skunk-Like Aroma in Scientific Peer-Reviewed Study

Retrieved on: 
Wednesday, November 17, 2021
Gelato, CBD, Sulfide, Family, Flower, Disulfide, Industry, Beer, ACS Omega, Terpene, Gasoline, Health, BHO, Technology, Gas chromatography, Growth, CSO, Research, Timeline of cannabis laws in the United States, Comprehensive, VSC, American Chemical Society, Mass spectrometry, Volatilisation, Drink, Food, History, Nature, Garlic, Time, Comprehensive two-dimensional gas chromatography, Cannabis, Flavonoid, Cosmetics, Medicinal plants, Perfume, Drug, Dietary supplement

Now, a team led by T.J. Martin of ABSTRAX has uncovered an entirely new family of compounds responsible for this scent.

Key Points: 
  • Now, a team led by T.J. Martin of ABSTRAX has uncovered an entirely new family of compounds responsible for this scent.
  • "Our data conclusively establishes a link between this new family of VSCs in cannabis and its pungent aroma."
  • However, cannabis presents a uniquely complex case due to the wide variety and number of aroma compounds present.
  • This is especially helpful in situations where compounds are in exceedingly low concentrations, including those discovered in this study.

Alcon to Launch TOTAL30 as the First-and-Only Monthly Replacement, Water Gradient Contact Lens

Retrieved on: 
Wednesday, August 11, 2021
Medical Supplies, Medical Devices, Health, Surgery, General Health, Optical, American Academy, Veni, vidi, vici, Patient, Quality of life, Lecture, Â, Retina, Trial of the century, 3D, Eye, U.S. Securities and Exchange Commission, Optometry, Bacteria, ACS Omega, Conference, NYSE, Lowe, Forward-looking statement, Mark (given name), Technology, Cornea, Approximation error, Private Securities Litigation Reform Act, CLEAR, Water, Cataract, General manager, Lens, Multimedia, Glaucoma, Lens (anatomy), Camera, Telescopic sight, Medical device, Microscope

Alcon (SIX/NYSE: ALC), the global leader in eye care dedicated to helping people see brilliantly, today announced plans to launch TOTAL30, the first-and-only monthly replacement, Water Gradient lens that feels like nothing, even on day 30.1 Using Alcons proprietary Water Gradient material first introduced with DAILIES TOTAL1 contact lenses, TOTAL30 delivers a premium wearing experience for reusable contact lens wearers.

Key Points: 
  • Alcon (SIX/NYSE: ALC), the global leader in eye care dedicated to helping people see brilliantly, today announced plans to launch TOTAL30, the first-and-only monthly replacement, Water Gradient lens that feels like nothing, even on day 30.1 Using Alcons proprietary Water Gradient material first introduced with DAILIES TOTAL1 contact lenses, TOTAL30 delivers a premium wearing experience for reusable contact lens wearers.
  • Reusable lenses account for an estimated 45% of the $9 billion global contact lens market.2
    This press release features multimedia.
  • The reusable, Water Gradient design of TOTAL30 is made possible by the introduction of new biomimetic CELLIGENT Technology.
  • Surface observations of lehfilcon A contact lens and human cornea using scanning transmissions electron microscopy; Alcon data on file, 2020.