ZZ

Granite’s “Saving By Shaving” Event Raises Another $3.5 Million for Boston Children’s Hospital

Retrieved on: 
Wednesday, February 28, 2024
Technology, Mobile, Wireless, Hospitals, Other Technology, Telecommunications, Other Health, Managed Care, Health, VoIP, Hale, Basketball, Multimedia, BCH, Hospital, Government, Hope, ZZ, Research

View the full release here: https://www.businesswire.com/news/home/20240228155887/en/

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20240228155887/en/
    Granite CEO Rob Hale presents a check to Kevin Churchwell, MD, President and CEO of Boston Children’s Hospital at Granite’s 11th Annual Saving by Shaving event.
  • The funds raised will continue Granite’s legacy of supporting Boston Children’s Hospital, contributing to essential pediatric research and treatments for future generations of children.
  • Echoing this sentiment, Kevin B. Churchwell, MD, President and CEO of Boston Children’s Hospital, added, "The unwavering support from Granite Telecommunications and the entire community through the 'Saving by Shaving' event is truly inspirational.
  • 1 most philanthropic company in Massachusetts on three occasions and has donated over $300 million to numerous charitable causes and initiatives.

Iconic Rock Band Lynyrd Skynyrd Launches Hell House Whiskey, a Tribute to Legendary Cabin

Retrieved on: 
Thursday, July 27, 2023
ZZ, Hell house, Sound, American whiskey, Music, Partnership, Record, Multimedia, Glass, Collection, Catalog, Nightclub

Today, they proudly announce the release of their highly anticipated new American Whiskey, Hell House Whiskey, paying homage to the famous cabin where they crafted countless legendary songs.

Key Points: 
  • Today, they proudly announce the release of their highly anticipated new American Whiskey, Hell House Whiskey, paying homage to the famous cabin where they crafted countless legendary songs.
  • Hell House Whiskey seeks to embody the very essence of where it all began - the iconic Hell House cabin.
  • "We are honored to collaborate with Lynyrd Skynyrd on the creation of Hell House Whiskey," expressed Peter Iglesias, CEO of Bespoken.
  • For more information, follow Hell House Whiskey on Instagram (@hellhousewhiskey) and Lynyrd Skynyrd (@skynyrd).

Sex and the single gene: new research shows a genetic ‘master switch’ determines sex in most animals

Retrieved on: 
Wednesday, April 19, 2023
Lizard, Male, Rat, Bass, Man, Human, Zebrafish, Vertebrate, XY, Turtle, Platypus, Intersex, Mammal, African, Y, Reproduction, X chromosome, SRY, Animal, Chromosome, Genome, Laboratory, Island, DMRT1, XX, W, XS, Bird, Gene, Female, Egg, Pig, Nightclub, Birth control, Toy, Agriculture, Antibiotics, ZZ

In humans and other animals, sex is usually determined by a single gene.

Key Points: 
  • In humans and other animals, sex is usually determined by a single gene.
  • We conclude that sex is normally determined by a single gene.

The human ‘master switch’ for sex

    • Females make eggs, which carry a single X chromosome, while males make sperm, half carrying an X and half carrying a Y.
    • Random fusion of eggs and sperm delivers half XX females and half XY males, for a 1:1 sex ratio.

Sex in other vertebrates

    • Among animals with backbones (vertebrates), there is a huge variety of systems that determine sex.
    • Some vertebrates have the opposite – a female-dominant gene on the X chromosome.
    • If the ratio favours one sex, individuals that produce more of the other sex will leave more descendants and their genes will spread until a 1:1 ratio is achieved.

Some exceptional species

    • Then there are species with two or more pairs of sex chromosomes.
    • And what about species, like the African clawed toad, which have two copies of their whole genome, so should have two pairs of sex chromosomes and sex genes?
    • So there are lots of exceptional species that seem to have multiple sex chromosomes and sex genes in defiance of the expectation that only a single sex gene can produce a stable system.

Polygenic sex – is there any such thing?

    • In our recent paper we examine classic examples and recent claims for polygenic sex determination.
    • Multiple sex chromosomes need not mean multiple sex genes.
    • A Japanese frog has different sex chromosomes on different islands, but they are all variants of the same chromosome.
    • Strains bred independently in laboratories for 30 or 40 years have aberrant sex ratios and multiple sex genes.

Winning the war of the sex genes

    • Their problem is incompatibility of different sex chromosomes and sex genes.
    • If an XY male mates with a ZW female, offspring have all sorts of combinations of sex genes.
    • Species hybrids may reveal many genes with major and minor effects on sex determination.
    • Read more:
      Men are slowly losing their Y chromosome, but a new sex gene discovery in spiny rats brings hope for humanity

Patriots’ Devin McCourty, Matthew Slater, Gov. Maura Healey and 800+ Granite Teammates Participate in Granite’s 10th Annual ‘Saving by Shaving’ Event to Benefit Boston Children’s Hospital

Retrieved on: 
Thursday, March 9, 2023
Other Philanthropy, State, Local, Telecommunications, Oncology, Networks, Internet, Football, Hospitals, Fund Raising, Foundation, Philanthropy, VoIP, Technology, Mobile, Wireless, Public Policy, Government, Sports, Health, Carriers and Services, History, Child, Friends, Research, Patriot, Lunch, Breakfast, Head, Radio, Patient, Cancer, Organic, Athlete, Multimedia, ZZ, Coffee, Hair, Volunteering, Hospital, Organization, Safety, BCH, New England Patriots, Personality, Pharmaceutical industry, Textile, Nursing, MD, Jay Lambert, Granite

View the full release here: https://www.businesswire.com/news/home/20230309005798/en/

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20230309005798/en/
    Granite CEO Rob Hale presents a check to Kevin Churchwell, MD, President and CEO of Boston Children’s Hospital at Granite’s 10th Annual Saving by Shaving event.
  • These include Boston Uncornered , a nonprofit selected by safety Devin McCourty, and Edmiston Center , a nonprofit selected by wide receiver Matthew Slater.
  • “I am proud of the Granite team and the greater community and how we work together to support the amazing work done by Boston Children’s Hospital.
  • From there, 428 teammates turned out at Granite’s first “Saving by Shaving” event and raised more than $2.2 million to benefit cancer research.

ZZ Biotech’s Stroke Drug Moves Closer to Pivotal Phase 3 Clinical Trial as the NIH Awards First Tranche of $30 Million Grant to the Keck School of Medicine of USC

Retrieved on: 
Tuesday, May 24, 2022
Science, Biotechnology, Research, Pharmaceutical, General Health, Health, FDA, Clinical Trials, Physician, Keck School of Medicine of USC, Inflammation, Death, Education, USC, Lists of diseases, Annals of Neurology, Medicine, Incidence, Doctor of Philosophy, National Institute of Neurological Disorders and Stroke, National Institute, Patient, ZZ, Health, APC, Clinical trial, Physiology, Bleeding, Endothelium, Feedback, Neurology, Trial of the century, Phase 3, NIH, Neuron, Neuro, FDA, Brain, Disability, NINDS, University, Neurological disorder, Wound healing, Fast Track, LLC, ALS, Pharmaceutical industry, Neuroscience, Stroke

The remainder of the grant will be funded in subsequent tranches, pending review of milestones over the 6-year grant period.

Key Points: 
  • The remainder of the grant will be funded in subsequent tranches, pending review of milestones over the 6-year grant period.
  • The primary endpoint of the trial is to test 3K3A-APC as a cerebroprotectant, a drug that hastens or augments recovery after stroke.
  • A secondary endpoint will gauge the efficacy of 3K3A-APC at minimizing brain bleeds when combined with two standard treatments for acute ischemic stroke.
  • This will be the second clinical trial of 3K3A-APC in stroke to be supported by grants from NINDS.

Patriots’ Mac Jones, Matt Light, Gov. Charlie Baker and 600 Granite Teammates Shave Their Heads to Benefit Boston Children’s Hospital

Retrieved on: 
Tuesday, March 1, 2022
Technology, Fund Raising, Foundation, Philanthropy, Hospitals, Celebrity, Sports, Entertainment, Health, Other Philanthropy, Telecommunications, VoIP, Networks, Internet, Mobile, Wireless, Football, Oncology, Telecommunication, ZZ, Patient, Research, Coffee, Breakfast, Radio, Organization, Hospital, Friends, Volunteering, Boston Children's Hospital, Hair, Multimedia, Head, Cancer, Time, Lunch, CEO, History, Child, Athlete, New England Patriots, Mass, Personality, Government, Pharmaceutical industry, Granite, Lambert Packard, Granite, Boston Children’s, Hair We Share, GRANITE, BOSTON CHILDREN’S, HAIR WE SHARE

View the full release here: https://www.businesswire.com/news/home/20220301006227/en/

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20220301006227/en/
    Granite CEO Rob Hale (far left) with (left to right) David Andrews (New England Patriots), Matt Light (New England Patriots), Boston Children's Hospital President and CEO Kevin Churchwell, Massachusetts Governor Charles Duane Baker Jr., Quincy (Mass.)
  • Mayor Thomas Koch, Mac Jones (New England Patriots) and Joe Andruzzi (New England Patriots) at the check presentation for the 9th Annual Saving by Shaving event.
  • Todays support for Boston Childrens Hospital is a testament to the grit and spirit of this company and our community in appreciation for the work that Boston Childrens Hospital does for children here in Boston and throughout the world.
  • Granite is truly having a lifesaving impact for so many at Boston Childrens Hospital, through their annual Saving by Shaving event.

'BLOCKCHAIN.COM MIAMI PADEL OPEN' ANNOUNCES FEBRUARY EVENT | February 22-27, 2022

Retrieved on: 
Monday, February 7, 2022
Pura, Industry, Female, Growth, Garden, Padel, Investment, Twitter, Financial services, BIG, City, Ros, Drink, Real estate, WPT, Circuit, Partner, Asset, Spectator, Male, List of NBA All-Stars, CEO, ZZ, Mark (given name), History, Blockchain.com, NBA, Aviation, Miami Heat, Blog, Music, Food, Insurance, Honorary, Club, VIP, Nightclub, Cryptocurrency, Drug, Technology, Island Gardens, Biscayne Bay

"Boich Investment Group, along with 777 Partners, are thrilled to bring the World Padel Tour to Miami this month," said Wayne Boich, Chairman and CEO of Boich Investment Group. "We, along with WPT, are committed to bringing a best-in-class experience to all of the players, fans, and partners that will take part in this inaugural event. Padel--the fastest growing sport in the world--has exploded in popularity right here in our backyard and this event is a fantastic opportunity to bring the best Padel players in the world to Miami. Fusing padel and entertainment, the experience will be a multi-faceted one for all in attendance."

Key Points: 
  • MIAMI, Feb. 7, 2022 /PRNewswire/ -- Miami-based investors, Boich Investment Group and 777 Partners, today announced that the World Padel Tour will begin its 2022 season in Miami, Florida.
  • 'Blockchain.com Miami Padel Open,' a six-day lifestyle and entertainment sporting event will take place at Island Gardens Miami, from February 22nd-27th.
  • Also supporting the event is a team of padel enthusiasts including Grinda Investments and Dani Homedes, Owner of the Wynwood Padel Club.
  • The Honorary Chairperson for this year's Blockchain.com Miami Padel Open is famed Miami Heat superstar and padel enthusiast, Jimmy Butler.

BMG and KKR Acquire Music Interests of Rock Icons ZZ Top

Retrieved on: 
Tuesday, December 21, 2021
Music, Entertainment, Diamond, Pressure, Twitter, Latham & Watkins, Gold, Music, Income, Life, Grammy Award for Best Music Film, Fast Company, El Loco, KKR, Insurance, Dusty Hill, Investment, Rock, Rock music, ZZ Top, Platinum, Gimme All Your Lovin', Tres Hombres, Penguin Random House, Bass, ZZ, Partnership, Retirement, Rock & Roll Hall of Fame Covers EP, RTL Group, Book, Growth, NYSE, Bertelsmann, BMG

Global music company BMG and global investment firm KKR today announced that they have acquired the entire music interests of American rock icons ZZ Top.

Key Points: 
  • Global music company BMG and global investment firm KKR today announced that they have acquired the entire music interests of American rock icons ZZ Top.
  • The ZZ Top agreement includes a buyout of the bands publishing catalogue and their income from recorded royalties and performance royalties.
  • ZZ Top manager Carl Stubner of Shelter Music Group said, We are proud to continue working with and expand our long-standing relationship with BMG.
  • For additional information about KKR & Co. Inc. (NYSE: KKR), please visit KKRs website at www.kkr.com and on Twitter @KKR_Co.

JDS Development Group and Major Food Group Announce MAJOR. -- a Dynamic New Residential and Hospitality Tower at 888 Brickell Avenue, and Tallest Skyscraper in Miami

Retrieved on: 
Friday, December 3, 2021
Founder CEO, MFG, CEO, Michelin Guide, Industry, Carbone, Alfredo Sadel, Barclays Center, Contessa, Acquisition, JDS, The Newbury Boston, Partnership, Ralph Thomas Walker, Poverty, Food group, Brickell Avenue, Rick Sofield, Bottega Veneta, MAJOR, American Copper Buildings, Steinway Hall, Restaurant, ZZ, Double Crown Club, Collection, JDS Development Group, Robin Hood Foundation, Food, Engineering, The New York Times, Hotel

: a new residential-hospitality tower located at 888 Brickell Avenue in Miami, Florida.

Key Points: 
  • : a new residential-hospitality tower located at 888 Brickell Avenue in Miami, Florida.
  • marks a milestone in the evolution of Major Food Group, which currently operates a global portfolio of over thirty restaurants, hotels, and private clubs.
  • "You haven't seen anything like MAJOR.," stated Michael Stern, Founder & CEO of JDS Development Group.
  • JDS also co-developed the record-breaking Echo Brickell condominium project and recently broke ground on the large-scale mixed-use 1 Southside Park in Brickell.

ZZ Biotech Announces First Patients Dosed in Phase 2 Clinical Trial of 3K3A-APC for Treatment of Amyotrophic Lateral Sclerosis (ALS)

Retrieved on: 
Thursday, December 2, 2021
Other Health, Research, General Health, Pharmaceutical, Mental Health, Clinical Trials, Science, Biotechnology, FDA, Other Science, Health, Diabetes, Patient, Research, University, Heart, Safety, Biomarker, Time, Industry, Brain, ALS, National Institute of Neurological Disorders and Stroke, Traffic barrier, Clinical trial, Student, Neurological disorder, Doctor of Philosophy, Neurodegeneration, National Institute, Macquarie University, APC, LLC, ZZ, Wound healing, Fast Track, Motor neuron disease, Amyotrophic lateral sclerosis, FDA, Lists of diseases, Disease, Stroke, Pharmaceutical industry, 3K3A-APC, ZZ Biotech, Macquarie University, 3K3A-APC, ZZ BIOTECH, MACQUARIE UNIVERSITY

The Firies Climb for Motor Neurone Disease provided an AU$1 million donation to support this clinical trial.

Key Points: 
  • The Firies Climb for Motor Neurone Disease provided an AU$1 million donation to support this clinical trial.
  • The Phase 2 open label trial (NCT05039268) will enroll a total of 16 patients with ALS into two dose cohorts.
  • ZZ Biotech has completed a Phase 2 clinical trial of 3K3A-APC in acute ischemic stroke patients called RHAPSODY.
  • ZZ Biotech has completed a successful National Institute of Neurological Disorder and Stroke-funded Phase 2 clinical study, RHAPSODY, in acute ischemic stroke patients.