PH

• Among the 3,395 patients involved in the study , more than 83% completed a UDS within 30 days.
• After 90 days, that number increased to 97.6% of patients, and after 180 days, 99.7% of patients had completed multiple UDSs.
• Patients self-administered a UDS off-screen during telehealth visits and clinicians visually inspected results and discussed them with the patient in real-time over video.
• Ophelia plans to conduct and publish additional research studies around the efficacy and safety of the TBOT model for OUD treatment.

• Many studies show that people with Crohn’s disease have a less diverse community of gut bacteria.
• But it isn’t only the gut’s bacteria that show signs of dysfunction in people with Crohn’s disease.
• Rather unexpectedly, research also shows that the bacteria in the mouth might also be important in this inflammatory condition.

Mouth microbiome

• As such, our mouth contains the second highest number of bacteria after the gut.
• There are a couple of reasons why researchers think the oral microbiome might play a role in Crohn’s disease.
• This could suggest that certain species of bacteria present in the mouth may play a role in Crohn’s disease.
• This is perhaps unsurprising, given the entry route of bacteria into the lower gut is generally via the mouth.
• In fact, it’s not uncommon for people with Crohn’s disease to develop ulcers in the mouth, alongside those commonly seen in the gut.

Other diseases

• In breast cancer, the oral bacteria Fusobacterium nucleatum has been linked with accelerated tumour growth and the spread of cancer cells.
• And although there’s plenty of data from mouse studies, more research showing this link in humans is needed.
• Medical Research Council
  Chief Scientist Office, Scotland
  Helmsley Charitable Trust
  Jon Moulton Foundation
  Crohn's and Colitis UK
  European Research Council

• SAN FRANCISCO, July 6, 2023 /PRNewswire-PRWeb/ -- A ground breaking study validated a significant advancement for accurate placement of nasogastric feeding tubes (FTs).
• The study, published in The International Journal of Applied and Basic Nutritional Sciences , was conducted on healthy subjects with and without acid suppression medication.
• Additionally, the study evaluated the use of gastric aspirate pH as a means of confirming tube location.
• "This study shows that the technology and process we've embedded in Entarik delivers significant progress toward those objectives."

• Some ant species are struggling to follow trails, as warming temperatures cause a certain pheromone they use to communicate to decay.
• And in coral reefs, the colourful and pretty damselfish are losing their ability to learn who their predators are.
• All have been caused in some way by arguably the biggest change of all: climate change.
• My colleagues and I have led research which has shown that climate change is also changing chemical communication in marine, freshwater and land-based species, with far-reaching implications for our planet’s future and human wellbeing.

Changing infochemicals

• An example of this is a laboratory experiment that showed how climate change caused a reduction in anti-predator behaviour in some fish species by decreasing their anxiety towards potential predators.
• Many fish release certain chemicals when they are harmed by a predator or are otherwise in danger.
• A growing number of studies suggest that climate change-associated stressors which modify these chemical interactions are causing info-disruption across whole ecosystems.
• Every Wednesday, The Conversation’s environment editor writes Imagine, a short email that goes a little deeper into just one climate issue.