Potency (pharmacology)

Bionano’s Symposium 2023 Featured Record Numbers of Presentations Demonstrating Applications of OGM Across Cell Bioprocessing and Constitutional Genetic Disease and Cancer Research

Retrieved on: 
Thursday, February 2, 2023

During this four-day online event, presenters reported on their use of OGM for applications in genetic disease, cancer and cell bioprocessing.

Key Points: 
  • During this four-day online event, presenters reported on their use of OGM for applications in genetic disease, cancer and cell bioprocessing.
  • OGM was highlighted by researchers as a high-performance, one-stop platform, potentially eliminating the need for multiple sequential testing.
  • Aside from high concordance with classical cytogenetic methods, OGM produced additional relevant findings in 52% of all analyzed samples.
  • (Day 2)
    OGM has additional potential applications, including cell bioprocessing QC, in academic and commercial laboratory settings.

Pluristyx and panCELLa Expand Intellectual Property Portfolio for Pluripotent Stem Cell Cloaking Technology

Retrieved on: 
Thursday, January 12, 2023

Pluristyx and panCELLa today are excited to announce the granting of a patent used in their universal, off-the-shelf, induced pluripotent stem cells (iPSCs).

Key Points: 
  • Pluristyx and panCELLa today are excited to announce the granting of a patent used in their universal, off-the-shelf, induced pluripotent stem cells (iPSCs).
  • The Great Britain Patent Office on January 4, 2023 issued patent number GB2588249B extending panCELLa’s protection of its induced Allogeneic Cell Tolerance (iACT Stealth™) technology (WO/2018/227286) to the United Kingdom.
  • The iACT Stealth™ technology is available for evaluation under the “Try-before-you-buy” research evaluation model as a stand-alone product or in combination with FailSafe® and SafeHarbor platform technologies.
  • We are extremely pleased with the grant of claims by the Great Britain patent office to protect our iACT Stealth™ technology.

Avectas Launches the Solupore® Platform for the Clinical Manufacturing of Next-Generation Gene-Modified Cell Therapies with Unparalleled Cell Health and Functionality

Retrieved on: 
Monday, January 16, 2023

Solupore technology works by temporarily permeabilizing the target cell membrane so that molecular cargoes such as mRNA, plasmids, RNP or CRISPR/Cas9 can be delivered while retaining superior cell health and function.

Key Points: 
  • Solupore technology works by temporarily permeabilizing the target cell membrane so that molecular cargoes such as mRNA, plasmids, RNP or CRISPR/Cas9 can be delivered while retaining superior cell health and function.
  • Launching our clinical manufacturing system brings us closer to fulfilling our vision of working with partners to accelerate the future of cell therapies for patients."
  • Caption: Solupore clinical manufacturing system for non-viral delivery to enable next-generation cell therapies.
  • Provides unparalleled cell health and superior cell functionality, expanding the possibilities for complex editing and challenging cargo delivery
    Easy to integrate into existing GMP processes, Solupore accelerates the translation of life-saving therapies to patients

Induced Pluripotent Stem Cells Production Global Market Report 2022: Sector to Reach $2.8 Billion by 2030 at a 9.2% CAGR

Retrieved on: 
Monday, January 9, 2023

The global induced pluripotent stem cells production market size is estimated to reach USD 2.8 billion by 2030.

Key Points: 
  • The global induced pluripotent stem cells production market size is estimated to reach USD 2.8 billion by 2030.
  • The increase in demand for induced pluripotent stem cells (iPSCs) in comparison to Embryonic Stem Cells (ESCs) has offered a significant drive to the market.
  • Induced pluripotent stem cells are cells that are derived from adult somatic cells and then further reprogrammed to obtain the pluripotency as that of ESCs.
  • The key factors driving the revenue growth are the developed healthcare infrastructure, the prevalence of chronic diseases, the presence of strategic business models and funds by supportive government
    Chapter 4 Induced Pluripotent Stem Cells (Ipscs) Production Market: Process Business Analysis
    Chapter 5 Induced Pluripotent Stem Cells (Ipscs) Production Market: Workflow Business Analysis
    Chapter 6 Induced Pluripotent Stem Cells (Ipscs) Production Market: Product Business Analysis
    Chapter 7 Induced Pluripotent Stem Cells (Ipscs) Production Market: Application Business Analysis
    Chapter 8 Induced Pluripotent Stem Cells (Ipscs) Production Market: End-User Business Analysis
    Chapter 9 Induced Pluripotent Stem Cells (Ipscs) Production Market: Regional Business Analysis

FUJIFILM Cellular Dynamics Announces License Agreement with Novo Nordisk for the Development of iPSC-Derived Cell Therapies

Retrieved on: 
Thursday, January 5, 2023

MADISON, Wis., Jan. 05, 2023 (GLOBE NEWSWIRE) -- FUJIFILM Cellular Dynamics, Inc., a leading global developer and manufacturer of human induced pluripotent stem cells (iPSC), announced today that it has entered an agreement to grant global healthcare company Novo Nordisk A/S a non-exclusive right to use FUJIFILM Cellular Dynamics’ iPSC platform for the development and commercialization of iPSC-derived cell therapies with a focus on addressing serious chronic diseases.

Key Points: 
  • MADISON, Wis., Jan. 05, 2023 (GLOBE NEWSWIRE) -- FUJIFILM Cellular Dynamics, Inc., a leading global developer and manufacturer of human induced pluripotent stem cells (iPSC), announced today that it has entered an agreement to grant global healthcare company Novo Nordisk A/S a non-exclusive right to use FUJIFILM Cellular Dynamics’ iPSC platform for the development and commercialization of iPSC-derived cell therapies with a focus on addressing serious chronic diseases.
  • Under the agreement, Novo Nordisk will have a non-exclusive license to use the iPSC cell lines for research and development purposes, and to utilize GMP-grade cell lines for clinical and commercial manufacture and commercialization of iPSC-derived cell therapies.
  • “FUJIFILM Cellular Dynamics is a global leader in the development and manufacturing of GMP-grade iPSCs for cell therapy applications.
  • Our goal is to drive the iPSC field forward by building strategic partnerships,” said Tomoyuki Hasegawa, chief executive officer, FUJIFILM Cellular Dynamics.

Induced Pluripotent Stem Cells Production Global Market Report 2022: Absence of Ethical Issues, Personalized Treatment Options and Flexibility Drive Adoption - ResearchAndMarkets.com

Retrieved on: 
Friday, January 6, 2023

The global induced pluripotent stem cells production market size is estimated to reach USD 2.8 billion by 2030.

Key Points: 
  • The global induced pluripotent stem cells production market size is estimated to reach USD 2.8 billion by 2030.
  • The increase in demand for induced pluripotent stem cells (iPSCs) in comparison to Embryonic Stem Cells (ESCs) has offered a significant drive to the market.
  • Advantages such as no stem cell-related ethical issues, personalized treatment, and flexibility during cell-based research have created a favorable scenario for market growth.
  • The key factors driving the revenue growth are the developed healthcare infrastructure, the prevalence of chronic diseases, the presence of strategic business models and funds by supportive government
    Chapter 4 Induced Pluripotent Stem Cells (Ipscs) Production Market: Process Business Analysis
    Chapter 5 Induced Pluripotent Stem Cells (Ipscs) Production Market: Workflow Business Analysis
    Chapter 6 Induced Pluripotent Stem Cells (Ipscs) Production Market: Product Business Analysis
    Chapter 7 Induced Pluripotent Stem Cells (Ipscs) Production Market: Application Business Analysis
    Chapter 8 Induced Pluripotent Stem Cells (Ipscs) Production Market: End-User Business Analysis
    Chapter 9 Induced Pluripotent Stem Cells (Ipscs) Production Market: Regional Business Analysis

I Peace, Inc. honored in BioSpectrum Asia Excellence Award 2022 with "Special Recognition in Cell Therapy"

Retrieved on: 
Wednesday, December 21, 2022

PALO ALTO, Calif., Dec. 21, 2022 /PRNewswire/ -- I Peace, Inc. ( https://www.ipeace.com ), has been awarded a "Special Recognition in Cell Therapy" during BioSpectrum Asia Excellence Award 2022 ceremony held in Singapore on December 2 ( https://www.biospectrumasia.com/news/115/21473/biospectrum-asia-announce... ).

Key Points: 
  • PALO ALTO, Calif., Dec. 21, 2022 /PRNewswire/ -- I Peace, Inc. ( https://www.ipeace.com ), has been awarded a "Special Recognition in Cell Therapy" during BioSpectrum Asia Excellence Award 2022 ceremony held in Singapore on December 2 ( https://www.biospectrumasia.com/news/115/21473/biospectrum-asia-announce... ).
  • I Peace supports research institutions and pharmaceutical companies around the globe by providing clinical-grade iPSCs conforming with regulatory standards both in the U.S. and Japan.
  • He founded I Peace, Inc. in 2015, aiming to transform iPSCs from a research tool to an essential commodity of life.
  • In 2021, the cell manufacturing facility Peace Engine Kyoto received a third-party certification as cGMP compliant.

Fujifilm Invests in PhenoVista Biosciences from its Life Sciences Corporate Venture Capital Fund

Retrieved on: 
Tuesday, December 13, 2022

This investment is from the Life Sciences Corporate Venture Capital (LS-CVC) strategic investment fund.

Key Points: 
  • This investment is from the Life Sciences Corporate Venture Capital (LS-CVC) strategic investment fund.
  • This investment builds upon the existing strategic alliance between FUJIFILM Corporation subsidiary, FUJIFILM Cellular Dynamics, Inc., a leading global developer and manufacturer of human iPSCs, and PhenoVista.
  • The new funding enables Fujifilm to access PhenoVista’s cutting-edge, imaging technologies and expertise and further strengthens the companies’ existing alliance.
  • The new investment will fund the creation of new, off-the-shelf Ready-2-Go Assay Services at PhenoVista using a broad range of FUJIFILM Cellular Dynamics’ iCell offerings.

Fujifilm’s Life Sciences Corporate Venture Capital Fund Invests in PhenoVista Biosciences

Retrieved on: 
Tuesday, December 13, 2022

FUJIFILM Corporations Life Sciences Corporate Venture Capital (LS-CVC) strategic investment fund is investing in PhenoVista to accelerate the development of new high-content screening (HCS) assay services using FUJIFILM iCell differentiated induced pluripotent stem cells (iPSCs) and PhenoVistas cutting-edge imaging technologies.

Key Points: 
  • FUJIFILM Corporations Life Sciences Corporate Venture Capital (LS-CVC) strategic investment fund is investing in PhenoVista to accelerate the development of new high-content screening (HCS) assay services using FUJIFILM iCell differentiated induced pluripotent stem cells (iPSCs) and PhenoVistas cutting-edge imaging technologies.
  • Fujifilms investment will accelerate an exciting phase of growth for PhenoVista, further solidifying our position as the leader in imaging-based analysis of complex cell models, said James G. Evans, CEO and co-founder of PhenoVista Biosciences.
  • Launched in February 2022, LS-CVC is a newly established group within Fujifilms Life Sciences Strategy Headquarters in Tokyo.
  • PhenoVista Biosciences is a leading provider of disease-relevant cell-based assay services based in San Diego, California.

Cognition Therapeutics Presents Scientific Rationale, Clinical Biomarker and Preclinical Data supporting a Phase 2 Clinical Trial with CT1812 in Geographic Atrophy Secondary to Dry AMD

Retrieved on: 
Thursday, December 1, 2022

Complement inhibition has shown potential in clinical trials but must be given via intravitreal injection to each affected eye.

Key Points: 
  • Complement inhibition has shown potential in clinical trials but must be given via intravitreal injection to each affected eye.
  • CT1812 is an experimental oral sigma-2 (-2) receptor modulator currently in Phase 2 clinical trials for both Alzheimer's disease and dementia with Lewy bodies (DLB).
  • The proteomic analyses from our clinical studies in neurodegenerative disease were instrumental in identifying dry AMD as an indication of interest, explained Mary Hamby, Ph.D. , VP of biology at Cognition Therapeutics.
  • We are currently investigating our lead candidate CT1812 in clinical programs in Alzheimers disease, dementia with Lewy bodies (DLB) and dry age-related macular degeneration (dry AMD).