MRAS

Use of SGLT2 Inhibitors Continues to Expand for the Treatment of Chronic Kidney Disease, with Eli Lilly/Boehringer Ingelheim’s Jardiance Making Significant Strides Following Label Expansion

Retrieved on: 
Wednesday, January 3, 2024

As the landscape grows more competitive, their role will be crucial in determining the success of brands like Farxiga and Jardiance.

Key Points: 
  • As the landscape grows more competitive, their role will be crucial in determining the success of brands like Farxiga and Jardiance.
  • This unique positioning compared to other agents was swiftly recognized by nephrologists, prompting them to express a clear preference for the brand.
  • Since the label expansion of Eli Lilly/Boehringer Ingelheim's Jardiance to include CKD, nephrologists have rapidly embraced this drug for both their DKD and non-diabetic CKD patients.
  • Several of these agents, including SGLT2 inhibitors and Kerendia, have demonstrated their effectiveness in slowing the progression of CKD.

Philogen S.p.A. announces receipt of the Good Manufacturing Practice Certificate for its new Production facility in Rosia (Siena, Italy) by Competent Authorities

Retrieved on: 
Tuesday, December 5, 2023

The certification was granted by the GMP MED office of the Agenzia Italiana del Farmaco (AIFA) following an inspection occurred in July 2023.

Key Points: 
  • The certification was granted by the GMP MED office of the Agenzia Italiana del Farmaco (AIFA) following an inspection occurred in July 2023.
  • AIFA confirmed that Philogen new facility complies with the requirements and guidelines of Good Manufacturing Practice outlined in the Directive 2003/94/EC issued by the European Parliament.
  • In the European Union, national competent authorities - AIFA in Italy - are responsible for inspecting manufacturing sites based within their own territories.
  • The Rosia facility will manufacture commercial supplies of Nidlegy™ and has been structured to address a global distribution of the product.

Government of Canada announces supports to improve well-being of health workers and help internationally educated health professionals enter the workforce more quickly

Retrieved on: 
Thursday, December 7, 2023

The Government of Canada will continue working with these organizations as well as other partners and provinces and territories to improve retention, increase recruitment, and advance efforts so that health workers and internationally educated health professionals can work across Canada more quickly.

Key Points: 
  • The Government of Canada will continue working with these organizations as well as other partners and provinces and territories to improve retention, increase recruitment, and advance efforts so that health workers and internationally educated health professionals can work across Canada more quickly.
  • These investments will help improve the well-being of dedicated health workers across Canada and ensure more internationally educated health professionals can put their skills and experience to work, benefitting Canadians from coast to coast to coast."
  • "Health professionals are the backbone of our health care system, but are facing many challenges affecting their own mental health.
  • These investments will help support the well-being of health workers and also improve workforce planning by helping to implement solutions that ensure internationally educated health professionals can begin working where they're needed most in Canada."

The Linux Foundation and Fintech Open Source Foundation (FINOS) Announce Keynote Speakers for Open Source in Finance Forum 2023

Retrieved on: 
Tuesday, October 3, 2023

NEW YORK, Oct. 3, 2023 /PRNewswire/ -- The Linux Foundation, the nonprofit organization enabling mass innovation through open source, and co-host Fintech Open Source Foundation (FINOS), a nonprofit whose mission is to accelerate adoption of open source software, standards, and best practices in financial services, today announced the keynote speakers for Open Source in Finance Forum New York 2023 (OSFF). The event will take place November 1st in New York City. The schedule can be viewed here.

Key Points: 
  • NEW YORK, Oct. 3, 2023 /PRNewswire/ -- The Linux Foundation , the nonprofit organization enabling mass innovation through open source, and co-host Fintech Open Source Foundation (FINOS), a nonprofit whose mission is to accelerate adoption of open source software, standards, and best practices in financial services, today announced the keynote speakers for Open Source in Finance Forum New York 2023 (OSFF).
  • Open Source in Finance Forum is the only conference dedicated to driving collaboration and innovation in financial services through open source software and standards.
  • This year, OSFF also plays host to numerous Linux Foundation project communities whose work has a positive impact in financial services.
  • Register TODAY for Open Source in Finance Forum for just US$375.

Ken’s rights? Our research shows Barbie is surprisingly accurate on how ‘men’s rights activists’ are radicalised

Retrieved on: 
Tuesday, July 25, 2023

The Kens however, reflecting the popularity of the dolls in the real world, play a mainly decorative role.

Key Points: 
  • The Kens however, reflecting the popularity of the dolls in the real world, play a mainly decorative role.
  • This is all to fix an error that is allowing the real world to seep into Barbie land, with symptoms such as Barbie having an existential crisis.
  • This sees him take a journey that is clearly influenced by, and pokes fun at, many aspects of contemporary anti-feminist men’s rights culture.

Barbieland and the matriarchy

    • It has been proposed that Barbieland is a matriarchy, but I would argue that their attitude to Kens is instead indifference.
    • This is not dissimilar to the grievances of some real-life men under contemporary feminism.
    • Having undertaken research on online antifeminist discourses, Ken’s journey from aggrievement to masculine “enlightenment” parallels themes we found in Men’s Rights Activist spaces.

The manosphere and MRAS

    • This includes MRAs (Men’s Rights Activists) who claim reverse discrimination and that feminism has gone too far, and Redpillers who claim to have swallowed the “red pill” to see the truth about feminism’s dominance.
    • Some of the most well known members of the manosphere are incels (involuntary celibates) a misogynistic community of self identified “beta-males” who want an end to women’s rights which prevent them from getting sex.

Ken’s grievances

    • Ken was being “friend-zoned” by Barbie, who despite being “boyfriend and girlfriend” wouldn’t let him stay over at the Dream House, because “every night is girl’s night”.
    • This is coupled with a feeling of not being special, as Ken is essentially interchangeable with any other Ken.
    • He takes patriarchy back to Barbieland and transforms it to Kendom, where the men change it to a society oriented around men and their power (and horses…).

Redpilled ken

    • This redpilled Ken is a hilarious parody of the “neomasculinity” of the pick up artist (PUA) movement, that seeks to restore a masculine-centred world.
    • Neomasculinity is about a belief in biological difference, traditional masculinity and heteronormative gender roles.

Finding the real Ken

    • But what of Just Beach Ken?
    • And what can we learn from this for preventing or managing radicalisation of this feeling of aggrievement in real men or boys?
    • Barbie encourages Ken to work out who he is outside of his relation to Barbie, and to learn being Just Ken is enough.

Alert Banners Dramatically Increase Prescribing Rates of Life-Saving Heart Failure Medication

Retrieved on: 
Sunday, March 5, 2023

NEW ORLEANS, March 5, 2023 /PRNewswire/ -- An automated system that flags which patients could most benefit from an underused yet life-saving cardiology drug more than doubled new prescriptions, according to a pilot program test by researchers at NYU Grossman School of Medicine.

Key Points: 
  • The trial applied the new tool to heart failure, the condition in which the heart is increasingly unable to pump enough blood.
  • Medications called mineralocorticoid receptor antagonists (MRAs) can greatly increase survival rates, but past studies had shown that almost two-thirds of eligible patients are not prescribed these drugs.
  • According to the study authors, it is the first to directly compare the effectiveness of alert message types that address heart failure.
  • Adults with heart failure were randomly divided into three groups based on the type of support tool used by their cardiologist.

Substantial Changes in Management of Patients with Chronic Kidney Disease as New Treatment Options Such as Bayer's Kerendia and SGLT2 Inhibitors Gain Traction in US and EU Markets

Retrieved on: 
Friday, January 20, 2023

EXTON, Pa., Jan. 20, 2023 /PRNewswire/ -- With SGLT2 inhibitors increasingly becoming the standard of care for diabetic and non-diabetic CKD patients, the broader CKD treatment has begun to change notably.

Key Points: 
  • Of note, while use of mineralocorticoid antagonists (MRAs) – including the newer option Kerendia (Bayer) – has increased over the past year, nephrologists indicate SGLT2 inhibitors remain their most likely first step for patients.
  • Since the approval of Kerendia in July 2021, the use of MRA products overall (inclusive of Kerendia, spironolactone, and eplerenone) in CKD non-dialysis patients has also grown substantially.
  • This research will build off the inaugural research in 2022 of 1,282 patients collected in collaboration with 263 European nephrologists.
  • Results of Spherix's second annual EU chart audit will publish later this spring with notable changes likely to appear.

Forsta Accelerates Innovation and Scales Capabilities to Advance the Market Research Industry

Retrieved on: 
Monday, November 28, 2022

Forsta , a leading global provider of market research, customer experience (CX) and employee experience (EX) technology, is reporting significant innovation and expansion of the companys market research technology offerings in the past six months.

Key Points: 
  • Forsta , a leading global provider of market research, customer experience (CX) and employee experience (EX) technology, is reporting significant innovation and expansion of the companys market research technology offerings in the past six months.
  • These combined capabilities enable market research and experience professionals to gather, analyze, visualize and act upon human insights.
  • "In just six months, Forstas acquisition by Press Ganey has become the catalyst for turbocharged innovation across our solutions serving the market research sector.
  • Forsta has a 30-year heritage of pioneering market research technology, and we intend to continue to innovate at rapid pace on a global scale to support the growth of our market research partners.

RewAir, Wind Turbine Engineering Company, Chooses Plataine to Optimize Their Production Lines, Reduce Costs and Carbon Footprint

Retrieved on: 
Tuesday, November 15, 2022

WALTHAM, Mass., Nov. 15, 2022 /PRNewswire-PRWeb/ -- RewAir, a global provider of engineering services to the wind turbine supply chain, selected Plataine's AI-based solution to optimize its wind blades production operations. RewAir will benefit from reduced production costs, improved material utilization rates and greater flexibility in its quoting and operational processes. Plataine's AI based technology was chosen due to the company's extensive experience at working with the wind energy sector, bringing value to its clients, and impacting the bottom line of the business. All this, while offering complete remote implementation and the strongest of aftersales support.

Key Points: 
  • RewAir will benefit from reduced production costs, improved material utilization rates and greater flexibility in its quoting and operational processes.
  • RewAir needed a flexible solution that allowed them to run an optimal production process on a variety of production lines.
  • Plataine's FabricOptimizer allows RewAir to optimize mix of material and operational costs for each of their different production lines.
  • RewAir provides engineering services that improve the efficiency of composite application manufacturing in wind turbine blade production.

Kanfit Increased Material Yield with Plataine's AI and IIoT Based Optimization Software

Retrieved on: 
Wednesday, September 7, 2022

WALTHAM, Mass., Sept. 7, 2022 /PRNewswire-PRWeb/ -- Kanfit, a leading manufacturer of parts and assemblies for aerospace, medical devices, and other industries—that deliver ready-to-fly assemblies and products made of composites and advanced metals—reveals how it benefits from Plataine's AI and IIoT based optimization solution by automating and streamlining its raw material tracking, management, and planning, to significantly reducing waste and production delays.

Key Points: 
  • Kanfit managed to address these challenges with Plataine's optimization solution, due to its strong experience in implementing Industry 4.0 solutions in the aerospace industry.
  • Plataine's Time sensitive Material Management (TSMM) solution prevents usage of expired material or material likely to expire by the time the work order is completed.
  • With Plataine's TSMM solution, material information is automatically collected from factory sensors and logged throughout the entire manufacturing process, eliminating manual reporting and paperwork.
  • The digitized and automated solution contributes to factory-wide benefits, improving overall efficiency, minimizing rework and waste, increasing material yield and ensuring compliance with audits.