CIDEB

Galmed Pharmaceuticals Provides Business Updates and Reports First Quarter 2021 Financial Results

Retrieved on: 
Thursday, May 13, 2021
Medical specialties, Anatomy, Hepatology, Branches of biology, Histopathology, Pathology, Steatosis, Alcohol and health, Liver, Bile acid, Fatty liver disease, CIDEB

b'Aramchol (arachidyl amido cholanoic acid) is a novel fatty acid bile acid conjugate, inducing beneficial modulation of intra-hepatic lipid metabolism.

Key Points: 
  • b'Aramchol (arachidyl amido cholanoic acid) is a novel fatty acid bile acid conjugate, inducing beneficial modulation of intra-hepatic lipid metabolism.
  • Aramchol\'s ability to modulate hepatic lipid metabolism was discovered and validated in animal models, demonstrating downregulation of the three key pathologies of NASH: steatosis, inflammation and fibrosis.
  • The effect of Aramchol on fibrosis is mediated by downregulation of steatosis and directly on human collagen producing cells.
  • It is the fastest growing cause of liver cancer and liver transplant in the U.S. due to the rise in obesity.

Galmed Pharmaceuticals to Report First Quarter 2021 Financial Results and Provide Business Update on Thursday May 13

Retrieved on: 
Thursday, May 6, 2021
Medical specialties, Anatomy, Hepatology, Branches of biology, Histopathology, Pathology, Steatosis, Alcohol and health, Liver, Bile acid, Fatty liver disease, CIDEB

b"Aramchol (arachidyl amido cholanoic acid) is a novel fatty acid bile acid conjugate, inducing beneficial modulation of intra-hepatic lipid metabolism.

Key Points: 
  • b"Aramchol (arachidyl amido cholanoic acid) is a novel fatty acid bile acid conjugate, inducing beneficial modulation of intra-hepatic lipid metabolism.
  • Aramchol's ability to modulate hepatic lipid metabolism was discovered and validated in animal models, demonstrating downregulation of the three key pathologies of NASH: steatosis, inflammation and fibrosis.
  • The effect of Aramchol on fibrosis is mediated by downregulation of steatosis and directly on human collagen producing cells.
  • It is the fastest growing cause of liver cancer and liver transplant in the U.S. due to the rise in obesity.