Synairgen announces results of in vitro studies showing antiviral activity of interferon beta against key SARS-CoV-2 variants
Interferon beta ('IFN-beta') is a naturally-occurring protein, which orchestrates the body's antiviral responses by triggering the production of hundreds of antiviral proteins which act across the viral replication cycle to confer broad-spectrum antiviral activity.
- Interferon beta ('IFN-beta') is a naturally-occurring protein, which orchestrates the body's antiviral responses by triggering the production of hundreds of antiviral proteins which act across the viral replication cycle to confer broad-spectrum antiviral activity.
- In vitro experiments were conducted at Viroclinics-DDL in the Netherlands to confirm that SNG001 had activity against the B.1.1.7 (UK or Kent) and B.1.351 (South African) variants.
- Concentrations, readily achievable following inhaled delivery of interferon beta, that gave 90% inhibition (IC90) were 3.2, 4.0 and 3.4 IU/mL respectively.
- Richard Marsden, CEO of Synairgen, added: As expected, these data confirm that SNG001 is a broad-spectrum antiviral product, now also demonstrating applicability against SARS-CoV-2 variants.