Incineration

Draft guideline on good agricultural and collection practice (GACP) for starting materials of herbal origin - Revision 1

Retrieved on:

Thursday, April 18, 2024

Reproduction, SCOPE, Eating, Pesticide, Convention, Change control, Confusion, Alkaloid, Climate, Fungus, Directive (European Union), Ethylene oxide, Wind, Wood, Glass, European Medicines Agency, HMPS, QDG, Hygiene, Water, Marketing, Fertilizer, Legislation, Manure, Distillation, Risk, Education, Committee, Compost, Draft, Policy, Person, EMA, Seed, Polycyclic aromatic hydrocarbon, Collection, Freezing, GMP, Risk assessment, GACP, Sunlight, Fermentation, Personal protective equipment, Animal, Herbal, Herbicide, Weather, INTRODUCTION, Documentation, Regeneration, Decontamination, EudraLex, Disease, International trade, European Pharmacopoeia, Part, Livestock, Public, Inhalation, Knowledge, Seedling, Factorization of polynomials, Record, Plant, Skin, API, Irrigation, Part Two, Soil, Directive, Pharmacopoeia, Codex, Guideline, Temperature, Attention, Hydrocarbon, Pyrrolizidine alkaloid, Polychlorinated biphenyl, Growth, Rotation, Incineration, Environment, Humidity, Smell, Ventilation, Light, Bird, Mineral, Fumigation, Pyrrolizidine, SOP, Housing, Smoking, Atmosphere, Postharvest, Rain, Liver, QWP, Medicinal plants

REFERENCES ....................................................................................................................................... 14

Key Points:

REFERENCES ....................................................................................................................................... 14
29

Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

Page 3/14

30

EXECUTIVE SUMMARY

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This guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin

37

1.
Due to the inherent
complexity of medicinal plants and herbal substances the quality of these starting materials requires an
adequate quality assurance system for the collection and/or cultivation, harvest, and primary
processing.
(either outdoor, indoor or in greenhouses) should be carefully considered, since each of the mentioned
types could have several problems and advantages.
The used cultivation method may be dependent on
the final application of the herbal medicinal product.
primary processing of herbal substances that are used for the preparation of herbal medicinal products.
medicinal plants and herbal substances, ensuring that they are handled appropriately throughout all
stages of cultivation, collection, processing and storage.
their preparations are exposed to a large number of environmental contaminants of both biotic and
abiotic origin.
to existing wildlife habitats and must adhere to CITES (Convention on International Trade in
Endangered species of Wild Fauna and Flora).
https://health.ec.europa.eu/document/download/bd537ccf-9271-4230-bca1-2d...
4 https://health.ec.europa.eu/document/download/fd318dd6-2404-4e67-82b0232...
3
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

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4.
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
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8.
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
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7.
Where possible, stable varieties and cultivars naturally
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
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resistant or tolerant to disease should preferably be used.
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
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The application should be carried out only by qualified staff using approved equipment.
The following should be noted:
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

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Damaged plants or plant parts need to be excluded or limited in accordance with a specific
pharmacopoeia monograph, where relevant.
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
Page 11/14

347
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directly to the sun (except in cases where there is a specific need) and must be protected from
rainfall, insect infestation, etc.
The label must be clear, permanently fixed and made from
6

Reflection paper on the use of fumigants (EMEA/HMPC/125562/2006)

Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

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non-toxic material.
Certain exudates that have not been subjected to a specific treatment are
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

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427

also considered to be herbal substances.
European Pharmacopoeia General Monograph ?HERBAL DRUGS? 07/2017:1433
Are obtained by subjecting herbal substances to treatments such as
extraction, distillation, expression, fractionation, purification, concentration
or fermentation.

Draft guideline on good agricultural and collection practice (GACP) for starting materials of herbal origin - Revision 1

Retrieved on:

Thursday, April 18, 2024

REFERENCES ....................................................................................................................................... 14

Key Points:

REFERENCES ....................................................................................................................................... 14
29

Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

Page 3/14

30

EXECUTIVE SUMMARY

31
32
33
34
35
36

This guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin

37

1.
Due to the inherent
complexity of medicinal plants and herbal substances the quality of these starting materials requires an
adequate quality assurance system for the collection and/or cultivation, harvest, and primary
processing.
(either outdoor, indoor or in greenhouses) should be carefully considered, since each of the mentioned
types could have several problems and advantages.
The used cultivation method may be dependent on
the final application of the herbal medicinal product.
primary processing of herbal substances that are used for the preparation of herbal medicinal products.
medicinal plants and herbal substances, ensuring that they are handled appropriately throughout all
stages of cultivation, collection, processing and storage.
their preparations are exposed to a large number of environmental contaminants of both biotic and
abiotic origin.
to existing wildlife habitats and must adhere to CITES (Convention on International Trade in
Endangered species of Wild Fauna and Flora).
https://health.ec.europa.eu/document/download/bd537ccf-9271-4230-bca1-2d...
4 https://health.ec.europa.eu/document/download/fd318dd6-2404-4e67-82b0232...
3
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

Page 5/14

104

4.
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
Page 6/14

147
148
149

8.
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
Page 7/14

185

7.
Where possible, stable varieties and cultivars naturally
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
Page 8/14

227
228

resistant or tolerant to disease should preferably be used.
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
Page 9/14

268
269
270
271
272
273

The application should be carried out only by qualified staff using approved equipment.
The following should be noted:
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

Page 10/14

309
310

?

311
312
313

?

314
315
316
317

?

318
319
320

?

321
322

?

323
324
325

?

326
327
328

?

Damaged plants or plant parts need to be excluded or limited in accordance with a specific
pharmacopoeia monograph, where relevant.
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005
Page 11/14

347
348

directly to the sun (except in cases where there is a specific need) and must be protected from
rainfall, insect infestation, etc.
The label must be clear, permanently fixed and made from
6

Reflection paper on the use of fumigants (EMEA/HMPC/125562/2006)

Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

Page 12/14

386
387

non-toxic material.
Certain exudates that have not been subjected to a specific treatment are
Guideline on Good Agricultural and Collection Practice (GACP) for starting materials of herbal origin
EMA/HMPC/246816/2005

Page 13/14

425
426
427

also considered to be herbal substances.
European Pharmacopoeia General Monograph ?HERBAL DRUGS? 07/2017:1433
Are obtained by subjecting herbal substances to treatments such as
extraction, distillation, expression, fractionation, purification, concentration
or fermentation.

Perma-Fix Successfully Completes Pilot Plant Testing and Unveils New Process for Destruction of PFAS “Forever Chemicals”

Retrieved on:

Wednesday, April 3, 2024

Present disposal options for PFAS liquids include deep wells, incineration and landfills, all of which have serious environmental liability issues.

Key Points:

Present disposal options for PFAS liquids include deep wells, incineration and landfills, all of which have serious environmental liability issues.
We expect that the Perma-Fix’s process will virtually eliminate PFAS compounds (minimum of 99.9999% destruction) and reduces the environmental liability associated with these materials.
Additionally, the process is designed to operate at a highly competitive price compared to traditional disposal options.
According to a recent article in Barron’s the estimated cleanup cost for PFAS compounds could exceed $200 billion.

Eastman Molecular Recycling Facility Achieves On-Spec Initial Production and Is Generating Revenue

Retrieved on:

Thursday, March 21, 2024

Packaging, Recycling, Chemicals, Plastics, Environment, Manufacturing, Other Manufacturing, Chairperson, Growth, Incineration, EMN

Eastman (NYSE: EMN) today announced it has achieved on-spec initial production and is generating revenue from its new molecular recycling facility in Kingsport, Tennessee.

Key Points:

Eastman (NYSE: EMN) today announced it has achieved on-spec initial production and is generating revenue from its new molecular recycling facility in Kingsport, Tennessee.
The company expects to ramp up production of the new facility over the coming months and enable growth across a wide range of markets.
“By demonstrating molecular recycling at this scale, we have solidified our position as a leader in the creation of a circular economy.
In addition to this recently completed facility in Kingsport, Eastman plans to invest in two additional molecular recycling plants, one in France and another U.S. site.

Battelle and Revive Environmental Technologies Officials Join Ohio Governor Mike DeWine to Announce Kickoff of PFAS Takeback Program

Retrieved on:

Monday, March 18, 2024

Mike DeWine and Ohio EPA Director Anne Vogel joined Battelle President and CEO, Lou Von Thaer, and Revive Environmental President and CEO, David Trueba, to announce the launch of the Ohio AFFF Takeback Program at an event near Wright State University.

Key Points:

Mike DeWine and Ohio EPA Director Anne Vogel joined Battelle President and CEO, Lou Von Thaer, and Revive Environmental President and CEO, David Trueba, to announce the launch of the Ohio AFFF Takeback Program at an event near Wright State University.
The Takeback program is designed to assist municipal fire departments in safely disposing of AFFFs as Ohio phases out these PFAS-containing firefighting foams.
The PFAS Annihilator® technology—the first-to-market total solution to remove and destroy toxic per- and polyfluoroalkyl substances (PFAS)—has been approved to permanently destroy aqueous film-forming foams (AFFFs) collected through the Ohio AFFF Takeback Program.
Using PFAS Annihilator® technology developed by Battelle , the Ohio AFFF Takeback Program will destroy PFAS in firefighting foam to non-detectable levels through the process of supercritical water oxidation.

Vanguard Renewables Celebrates a Decade of Clean Energy Innovation

Retrieved on:

Wednesday, March 13, 2024

Vanguard Renewables®, a farm-based provider of organic material solutions for the food and beverage industry, is celebrating a decade in clean energy innovation and organic materials solutions.

Key Points:

Vanguard Renewables®, a farm-based provider of organic material solutions for the food and beverage industry, is celebrating a decade in clean energy innovation and organic materials solutions.
As part of its aggressive growth strategy, Vanguard Renewables is developing multiple Farm Powered® digesters across the country that will service almost every major metropolitan market.
“When we launched Vanguard Renewables in 2014, I was researching why something that had been so successful in Europe had not been replicated in the United States,” stated John Hanselman, Chief Strategy Officer at Vanguard Renewables.
With a team of dedicated solutions providers, world-class scientists and engineers, strong leadership, and dedicated institutional partners Vanguard Renewables is well-positioned to drive the adoption of renewable energy solutions across the country for the next decade and beyond.

Mars Veterinary Health pilots industry-leading anaesthetic gas capture technology to reduce carbon emissions

Retrieved on:

Wednesday, April 3, 2024

Sustainability, Waltham Petcare Science Institute, Incineration, Environment, Partnership, History, Carbon, Carl Linnaeus, Pet, RCVS

BIRMINGHAM, England, April 3, 2024 /PRNewswire/ -- Mars Veterinary Health, through its UK veterinary group Linnaeus and in partnership with Waltham Petcare Science Institute, today announced a first-of-its-kind partnership with SageTech Veterinary to pilot an innovative anaesthetic gas capture solution to help prevent harmful greenhouse gases from entering the atmosphere.

Key Points:

BIRMINGHAM, England, April 3, 2024 /PRNewswire/ -- Mars Veterinary Health , through its UK veterinary group Linnaeus and in partnership with Waltham Petcare Science Institute , today announced a first-of-its-kind partnership with SageTech Veterinary to pilot an innovative anaesthetic gas capture solution to help prevent harmful greenhouse gases from entering the atmosphere.
These waste anaesthetic agents can then be extracted from the filter, avoiding current routes for disposal of volatile anaesthetic agents of incineration or release into the atmosphere.
Mars Veterinary Health aims to use these learnings to explore the potential application of this technology across other parts of its business in the years to come.
"At SageTech Veterinary, we are excited to share our developed technology and work alongside Mars Veterinary Health to significantly reduce the carbon footprint associated with the direct release of waste volatile anaesthetic agents to the environment," said Iain Menneer, CEO of SageTech Medical.

Mars Veterinary Health pilots industry-leading anaesthetic gas capture technology to reduce carbon emissions

Retrieved on:

Wednesday, April 3, 2024

Sustainability, Waltham Petcare Science Institute, Incineration, Environment, Partnership, History, Carbon, Carl Linnaeus, Pet, RCVS

BIRMINGHAM, England, April 3, 2024 /PRNewswire/ -- Mars Veterinary Health, through its UK veterinary group Linnaeus and in partnership with Waltham Petcare Science Institute, today announced a first-of-its-kind partnership with SageTech Veterinary to pilot an innovative anaesthetic gas capture solution to help prevent harmful greenhouse gases from entering the atmosphere.

Key Points:

BIRMINGHAM, England, April 3, 2024 /PRNewswire/ -- Mars Veterinary Health , through its UK veterinary group Linnaeus and in partnership with Waltham Petcare Science Institute , today announced a first-of-its-kind partnership with SageTech Veterinary to pilot an innovative anaesthetic gas capture solution to help prevent harmful greenhouse gases from entering the atmosphere.
These waste anaesthetic agents can then be extracted from the filter, avoiding current routes for disposal of volatile anaesthetic agents of incineration or release into the atmosphere.
Mars Veterinary Health aims to use these learnings to explore the potential application of this technology across other parts of its business in the years to come.
"At SageTech Veterinary, we are excited to share our developed technology and work alongside Mars Veterinary Health to significantly reduce the carbon footprint associated with the direct release of waste volatile anaesthetic agents to the environment," said Iain Menneer, CEO of SageTech Medical.

Korea's Leading Metaverse Carrieverse, Reaches 100k Global DAU

Retrieved on:

Monday, April 1, 2024

Incineration, Google Play, DAU, Active users, Shithead (card game), Blockchain, Multimedia, Movement, Cryptocurrency

According to Carrieverse, the DAU, which exceeded 150,000 after its global launch on Thursday remained above 100,000 as of Sunday.

Key Points:

According to Carrieverse, the DAU, which exceeded 150,000 after its global launch on Thursday remained above 100,000 as of Sunday.
The gross sales also reached new heights, ranking 16th in all games and 4th casual games in Thailand.
In the global metaverse, it reached the Top 100 Casual ranks in 86 countries around the world, and is well positioned to be another strong K-game.
As of March 28th, when the global launch took place, it topped the global blockchain game ranking site, Play2Earn.net, and remained in the top 2 until Sunday.

Aker Carbon Capture awarded pre-FEED from Statkraft in Norway

Retrieved on:

Monday, April 1, 2024

Carbon, CCS, Electricity, Knudsen, CO2, Incineration

OSLO, Norway, April 1, 2024 /PRNewswire/ -- Aker Carbon Capture has been awarded a pre-FEED for Statkraft's Heimdal waste-to-energy plant for capturing 220.000 tonnes of CO2 per year.

Key Points:

OSLO, Norway, April 1, 2024 /PRNewswire/ -- Aker Carbon Capture has been awarded a pre-FEED for Statkraft's Heimdal waste-to-energy plant for capturing 220.000 tonnes of CO2 per year.
The pre-FEED covers CO2 capture, compression, purification, liquefaction, and temporary storage of CO2 at the Heimdal waste-to-energy plant.
In 2023, Aker Carbon Capture was awarded a full FEED by Hafslund Oslo Celsio, the largest supplier of district heating in Norway, to develop carbon capture at their waste-to-energy facility at Klemetsrud in Oslo, Norway.
Statkraft looks forward to continuing the good dialogue with Aker Carbon Capture, and not least studying the report from Aker when it is completed in the autumn.