Irritability

Getting a good night’s rest is vital for neurodiverse children – pediatric sleep experts explain why

Retrieved on: 
Friday, April 19, 2024

If you’re a parent with kids at home, it often leaves you and your children on edge.

Key Points: 
  • If you’re a parent with kids at home, it often leaves you and your children on edge.
  • Children with neurodiverse conditions, such as autism and attention-deficit/hyperactivity disorder, or ADHD, are even more susceptible to the effects of poor sleep, given their emotional reactivity and impulsivity..
  • Struggles with sleep have been linked to increased aggression, irritability, inattention and hyperactivity in children with autism spectrum disorder.

The science behind sleep difficulties

  • There are multiple reasons why neurodiverse children don’t sleep well, including medical conditions, biological causes and behavioral and environmental factors.
  • Medical conditions, such as obstructive sleep apnea or epilepsy, can affect a child’s sleep.
  • Medications that are used to treat medical conditions, such as antidepressants for mood disorders or stimulants for ADHD, can further disrupt sleep.

Treating sleep problems


All of these factors can be addressed and treated. A thorough evaluation by the child’s health care provider may reveal a medical cause, or medication, that is interfering with sleep. Behavioral approaches can make a big difference in improving sleep. These might include:
Changes to daytime habits, including getting lots of morning light and physical activity.
Shifts in evening habits, such as removing all screens (TV, computers, phones, etc.) and establishing calming bedtime routines.
Modifications to how a parent interacts with their child for those families who would like a child to fall asleep and stay asleep independently.

  • It’s important to note that not all families want their children to sleep on their own.
  • Because there are so many factors that can cause disrupted sleep, addressing sleep problems cannot be a one-size-fits-all approach and should be done in partnership with parents.
  • Our team has developed a family-centered approach to address sleep problems in neurodiverse children.

The ups and downs of melatonin

  • While behavioral approaches are recommended as a first-line treatment, melatonin can be helpful in jump-starting a behavioral routine.
  • Overdoses can result from children eating a bunch of gummies, or parents not understanding how much melatonin is safe to give.
  • To help parents sift through all the resources and articles on melatonin on the internet and social media, one of us created a video and wrote several blogs on melatonin safety.
  • These include topics like whether children can become dependent on melatonin supplements over time, whether taking melatonin will delay puberty, whether children might experience side effects from taking melatonin and more.

Promoting healthier sleep


Here are some general tips for helping your child sleep better, regardless of whether they are neurodiverse:
Choose a consistent bedtime and wake time. This consistency will help children’s own natural melatonin kick in.
Make sure bedtime isn’t too early. For example, an 8 p.m. bedtime is too early for most 10-year-olds. Neurodiverse children may struggle to sleep and will become more anxious, which makes going to sleep even harder.
Help your child get natural sunlight in the morning. Morning sunlight sets our brain’s internal clock so that we can fall asleep more easily at bedtime.
Ensure your child is getting physical activity during the day.
Minimize naps longer than one hour, or after 4 p.m. for school-age children. Naps can interfere with going to sleep at night.
Avoid caffeine, including many types of soda, tea and chocolate.
Turn off all screens and smartphones at least 30 minutes before bedtime.
In the evening leading up to bedtime, turn down all lights in the house. Consider using red night lights, if possible. Set any devices to night mode in the evening to limit exposure to blue light.
Create wind-down time in place of screens. Have your child identify an activity they enjoy that is calming and soothing, such as reading a book, coloring or listening to music. If a bath is stimulating, move it to earlier in the evening, such as after dinner.
Help your child learn to fall asleep without needing you or their devices to be there with them. That way, they will settle down on their own at bedtime. And when they wake up throughout the night, since we all wake up in the night, they will be able to go right back to sleep without becoming fully awake.
For more tips, see Autism Speaks for free downloads of brochures and visual aids.

  • She also receives funding from the American Academy of Sleep Medicine.
  • She has received funding from the American Academy of Sleep Medicine and Autism Speaks for research on sleep in children with ASD.

Perinatal depression linked with premenstrual mood disorders – new research

Retrieved on: 
Friday, April 5, 2024

But for the millions of women who have a premenstrual disorder, such as severe premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD), these mood changes can be far more severe than normal.

Key Points: 
  • But for the millions of women who have a premenstrual disorder, such as severe premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD), these mood changes can be far more severe than normal.
  • Premenstrual disorders manifest through a range of symptoms – including mood swings, irritability and fatigue.
  • Our study found that women who have a premenstrual disorder may also be at greater risk of depression during or after pregnancy.
  • Having a premenstrual disorder may also partly explain why mental health problems may be more common in young women.

Perinatal depression

  • The hormonal fluctuations that happen during and after pregnancy can also precipitate a unique form of turmoil: perinatal depression.
  • Historically, the threads connecting premenstrual disorders and perinatal depression have been recognised anecdotally.
  • We revealed that women with a history of premenstrual disorders are five times more susceptible to developing perinatal depression if they become pregnant.
  • Read more:
    Maternal mental health problems – the impact in numbers

    Moreover, our study is the first to draw connections not just to postnatal depression (depression after childbirth) but also antenatal depression (depression during pregnancy).

  • We also showed that women who experience perinatal depression are at a higher risk of encountering premenstrual disorders later on.

Advocate for mental health

  • It also suggests that women with a history of premenstrual disorders should be closely screened for perinatal depression, and provided with the help and resources they may need for their mental health before and during pregnancy, and just after giving birth.
  • Moreover, it encourages women themselves to advocate for their mental health, armed with the understanding that their experiences before and during pregnancy are not isolated – but part of a broader hormonal narrative that needs addressing.


Donghao Lu receives funding from the Swedish Research Council, Swedish Research Council for Health, Working Life and Welfare, and Karolinska Institutet.

March Madness brings unique gambling risks for college students

Retrieved on: 
Wednesday, April 3, 2024

Beneath the surface of this annual sports event, however, lies a darker reality: the dangers of sports betting and gambling addiction.

Key Points: 
  • Beneath the surface of this annual sports event, however, lies a darker reality: the dangers of sports betting and gambling addiction.
  • While the majority of college students who are of legal age to gamble do so responsibly, one organization estimates that 6% of U.S. college students have a serious gambling problem that can result in psychological difficulties, unmanageable debt and failing grades.
  • A 2022 report found more than 1 in 5 college students have used their financial aid to gamble.

A growing part of sports culture

  • These days, it’s impossible for sports fans to watch a game without seeing or hearing an ad that beckons them to place a bet.
  • The constant bombardment of betting promotions during March Madness can desensitize individuals to the risks involved, leading to impulsive decision-making and related behavior.
  • A 2023 NCAA survey of 3,527 young people ages 18-22 found that sports wagering is pervasive among this group.

Ubiquitous gambling ads, risky behavior

  • This is a higher rate than found in the general population or those that commute or attend college virtually.
  • Problem gambling shows up in this population, with 16% having engaged in at least one additional risky behavior such as alcohol and drug use.
  • Meanwhile, 70% of these risky gamblers believe consistent sports gambling will increase their monetary earnings.

Starts out fun

  • For some college students, gambling for fun can turn into a serious problem.
  • Gambling addiction includes all gambling behavior patterns that compromise, disrupt or damage personal and family relationships or vocational pursuits.

Lowering the risks

  • While March Madness may be a time of excitement for sports fans, it’s essential to recognize the potential pitfalls and take steps to mitigate the risks.
  • Organizations such as the National Council on Problem Gambling provide confidential support and can connect individuals with services and treatment programs tailored to their needs.
  • Call or text their helpline at 1-800-GAMBLER, chat with helpline counselors at www.1800gamblerchat.org, find a treatment facility or attend a self-help meeting.


M. Dolores Cimini receives funding from the Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services, to conduct research on substance use and addictions, mental health, and related risk behaviors among college students.

Herbal medicinal product: Agni casti fructusArray, C: ongoing call for scientific data

Retrieved on: 
Friday, February 16, 2024

Herbal medicinal product: Agni casti fructusArray, C: ongoing call for scientific data

Key Points: 


Herbal medicinal product: Agni casti fructusArray, C: ongoing call for scientific data

Think You May Be Stressed? Here are 3 Physical Signs of Chronic Stress from The Chicago School President, Dr. Michele Nealon, Psy.D.

Retrieved on: 
Tuesday, February 13, 2024

Finding ways to manage stress levels is critical to our mental and physiological health and wellness, according to Dr. Michele Nealon, a clinical psychologist, and President of the Chicago School.

Key Points: 
  • Finding ways to manage stress levels is critical to our mental and physiological health and wellness, according to Dr. Michele Nealon, a clinical psychologist, and President of the Chicago School.
  • Dr. Nealon has said, “Stress can cause major mental health challenges over time.
  • Specifically, chronic stress can lead to anxiety and depression and can also cause chronic health conditions such as high blood pressure, increased risk of stroke, and substance abuse challenges.
  • Rest assured that you are not alone in your battle with chronic stress, no matter how isolating it may feel.

Emerging Filmmaker, Mirejah Cruz, Garners Acclaim for Award-Winning Short Film "Hell Week"

Retrieved on: 
Wednesday, February 7, 2024

LOS ANGELES, Feb. 7, 2024 /PRNewswire/ -- Mirejah Cruz, an up-and-coming actor and filmmaker, is rapidly gaining recognition for her groundbreaking work in the industry. Her latest project, the award-winning short film Hell Week, has captivated audiences and critics alike with its poignant exploration of Premenstrual Dysphoric Disorder (PMDD).

Key Points: 
  • Her latest project, the award-winning short film Hell Week, has captivated audiences and critics alike with its poignant exploration of Premenstrual Dysphoric Disorder (PMDD).
  • The film has resonated deeply with viewers, sparking important conversations about mental health, women's experiences and the medical industry.
  • The film's impact is undeniable, with Hell Week already selected for participation in eight prestigious film festivals, including the California Women's Film Festival and the London International Short Film Festival.
  • Hell Week is directed by Kassandra Mahea, written by Mirejah Cruz and produced by Damon Cirulli and Mirejah Cruz.

Working from home since COVID-19? Cabin fever could be the next challenge

Retrieved on: 
Tuesday, January 16, 2024

However, being confined to our homes for long periods without access to different activities can expose teleworkers to cabin fever, a lack of motivation and anxiety.

Key Points: 
  • However, being confined to our homes for long periods without access to different activities can expose teleworkers to cabin fever, a lack of motivation and anxiety.
  • Being at home for extended periods of time can leave some feeling like they’re experiencing cabin fever.
  • Whether moving away from the city or staying downtown, working fully remotely can trigger cabin fever if teleworkers develop bad habits and behaviours.
  • Such activities can provide necessary breaks from the confines of their homes, helping to prevent cabin fever and foster healthy teleworking habits and behaviours.

School uniforms may trigger sensory overload in kids who are sensitive to fabrics – our research can help

Retrieved on: 
Wednesday, January 3, 2024

Those with this condition experience an over-reaction to sensory stimuli, such as touch.

Key Points: 
  • Those with this condition experience an over-reaction to sensory stimuli, such as touch.
  • When overstimulated, the brain triggers a fight-or-flight response, which can lead to irritability, withdrawing from people, and temper tantrums.
  • Clothing plays a role in worsening these sensory issues because it remains in constant contact with the skin, providing sensory input.

Our study

  • The team’s first study focused on school uniforms.
  • The main reason for this is that they feel restricted and that the clothes are in very close contact with the skin.
  • Parents also mentioned that children often preferred second-hand school uniforms, which they experienced as softer and more tolerable than new items.
  • Apart from providing rich data about clothing and textiles, the study revealed the effect of the clothing on the participation of a child in their daily activities (such as education).

Simple interventions help

  • The good news is that simple interventions can make a substantial, positive difference.
  • Awareness of these realities should be highlighted and interventions should focus on improving outcomes not just for the child but for their entire family.

More to come

  • We are also conducting a separate analysis on the tactile properties of various textiles used in children’s wear.
  • The school uniform study was co-authored by Masters student Wenette Jordaan and Leoné Gouws, also a Masters student, is a co-author of the underwear study.


The work is based on the research supported wholly/ in part by the National Research Foundation of South Africa (Grant Number: 129842). Karin van Niekerk does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Human medicines European public assessment report (EPAR): Flucelvax Tetra, influenza vaccine (surface antigen, inactivated, prepared in cell cultures), Date of authorisation: 12/12/2018, Revision: 15, Status: Authorised

Retrieved on: 
Tuesday, January 2, 2024

Human medicines European public assessment report (EPAR): Flucelvax Tetra, influenza vaccine (surface antigen, inactivated, prepared in cell cultures), Date of authorisation: 12/12/2018, Revision: 15, Status: Authorised

Key Points: 


Human medicines European public assessment report (EPAR): Flucelvax Tetra, influenza vaccine (surface antigen, inactivated, prepared in cell cultures), Date of authorisation: 12/12/2018, Revision: 15, Status: Authorised

Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), COVID-19 mRNA vaccine,elasomeran,elasomeran / imelasomeran,elasomeran / davesomeran,andusomeran, Date of authorisation: 06/01/2021, Revision: 41[...]

Retrieved on: 
Tuesday, January 2, 2024

Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), COVID-19 mRNA vaccine,elasomeran,elasomeran / imelasomeran,elasomeran / davesomeran,andusomeran, Date of authorisation: 06/01/2021, Revision: 41, Status: Authorised

Key Points: 


Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), COVID-19 mRNA vaccine,elasomeran,elasomeran / imelasomeran,elasomeran / davesomeran,andusomeran, Date of authorisation: 06/01/2021, Revision: 41, Status: Authorised