DSF

JNCCN: Mismatch in Breast Cancer Trial Results and Real-World Outcomes Based on Treatment Discontinuation

Retrieved on: 
Tuesday, June 21, 2022

PLYMOUTH MEETING, Pa., June 21, 2022 /PRNewswire/ -- New research in the June 2022 issue of JNCCN—Journal of the National Comprehensive Cancer Network raises issues with clinical trial findings that show adjuvant hormone therapy (AHT)-related hot flashes predict better outcomes for estrogen receptor-positive (ER+) breast cancer. The population-based study looked at 7,152 chemotherapy-free patients with breast cancer in Sweden between 2006 and 2019 and found patients who were treated for hot flashes after beginning AHT were actually more likely to have worse outcomes. Patients who were subsequently treated for hot flashes had a 14.2% higher early discontinuation rate, which may account for the significantly shorter length of disease-free survival (DSF).

Key Points: 
  • "Cancer care providers need to be aware that prescribing symptom-relieving drugs to patients with treatment-related side effects may not be enough to prevent treatment discontinuation."
  • Hot flashes were one of the most common side effects, but only led to an 8%-28% rate of treatment discontinuation.
  • "Precision medicine based on the patient's genetic background may help to reduce treatment discontinuation," said senior author Kamila Czene, PhD, Karolinska Institutet.
  • Complimentary access to " Adjuvant Hormone Therapy-Related Hot Flashes Predict Treatment Discontinuation and Worse Breast Cancer Prognosis " is available until September 10, 2022.

JNCCN: Mismatch in Breast Cancer Trial Results and Real-World Outcomes Based on Treatment Discontinuation

Retrieved on: 
Tuesday, June 21, 2022

PLYMOUTH MEETING, Pa., June 21, 2022 /PRNewswire/ -- New research in the June 2022 issue of JNCCN—Journal of the National Comprehensive Cancer Network raises issues with clinical trial findings that show adjuvant hormone therapy (AHT)-related hot flashes predict better outcomes for estrogen receptor-positive (ER+) breast cancer. The population-based study looked at 7,152 chemotherapy-free patients with breast cancer in Sweden between 2006 and 2019 and found patients who were treated for hot flashes after beginning AHT were actually more likely to have worse outcomes. Patients who were subsequently treated for hot flashes had a 14.2% higher early discontinuation rate, which may account for the significantly shorter length of disease-free survival (DSF).

Key Points: 
  • "Cancer care providers need to be aware that prescribing symptom-relieving drugs to patients with treatment-related side effects may not be enough to prevent treatment discontinuation."
  • Hot flashes were one of the most common side effects, but only led to an 8%-28% rate of treatment discontinuation.
  • "Precision medicine based on the patient's genetic background may help to reduce treatment discontinuation," said senior author Kamila Czene, PhD, Karolinska Institutet.
  • Complimentary access to " Adjuvant Hormone Therapy-Related Hot Flashes Predict Treatment Discontinuation and Worse Breast Cancer Prognosis " is available until September 10, 2022.

Longboard Pharmaceuticals to Participate in Five Upcoming Epilepsy-Focused Conferences this Summer

Retrieved on: 
Wednesday, June 1, 2022

"We are pleased to be included in these key epilepsy conferences this summer.

Key Points: 
  • "We are pleased to be included in these key epilepsy conferences this summer.
  • LP352 is designed to modulate GABA and, as a result, suppress the central hyperexcitability that is characteristic of seizures.
  • Longboard Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing novel, transformative medicines for neurological diseases.
  • Longboard disclaims any intent or obligation to update these forward-looking statements, other than as may be required under applicable law.

Mage™ Joins Imperva Technology Alliance Program

Retrieved on: 
Tuesday, April 19, 2022

NEW YORK, April 19, 2022 /PRNewswire/ -- Mage has signed a technology partnership agreement with Imperva to provide a data masking alternative to Imperva's Data Security Fabric (DSF) built-in capabilities for de-identifying sensitive data.

Key Points: 
  • NEW YORK, April 19, 2022 /PRNewswire/ -- Mage has signed a technology partnership agreement with Imperva to provide a data masking alternative to Imperva's Data Security Fabric (DSF) built-in capabilities for de-identifying sensitive data.
  • "We are excited to have Mage join our growing technology ecosystem," says Farzad Tari, VP, Strategic Partnerships and Corporate Development, Imperva.
  • "Through this technology partnership with Mage, customers can stay on top of privacy regulations while ensuring the security and privacy of data by masking it."
  • Rajesh Parthasarathy, CEO of Mage added, "This technology partnership between Imperva and Mage will be a great enabler for organizations looking for a top-notch solution to tackle their data security needs.

Janus Henderson Foundation Bolsters Education Initiatives With Over US$1.35 M of Grants Planned For 2022

Retrieved on: 
Monday, April 11, 2022

The Janus Henderson Foundation, Janus Henderson Investors charitable giving arm, has established agreements to award more than US$1.35 million to charity partners around the globe in 2022, much of which is earmarked for financial literacy and other education initiatives.

Key Points: 
  • The Janus Henderson Foundation, Janus Henderson Investors charitable giving arm, has established agreements to award more than US$1.35 million to charity partners around the globe in 2022, much of which is earmarked for financial literacy and other education initiatives.
  • While the Janus Henderson Foundation supports many charities in the regions it does business in, it generally focuses on education initiatives, with a history of giving that started in 1994.
  • Janus Henderson Investors is the name under which investment products and services are provided by Janus Henderson Investors International Limited (reg no.
  • [Janus Henderson, Janus, Henderson, VelocityShares, Knowledge Shared, Knowledge.

Imperva Data Security Fabric Provides Bold New Approach to Securing All Data in Multicloud and Hybrid Environments

Retrieved on: 
Tuesday, April 5, 2022

Imperva, Inc. , ( @Imperva ) the comprehensive digital security leader, introduces the Imperva Data Security Fabric (DSF) to modernize and simplify data governance, security, and workflow management for all data across multicloud and hybrid environments.

Key Points: 
  • Imperva, Inc. , ( @Imperva ) the comprehensive digital security leader, introduces the Imperva Data Security Fabric (DSF) to modernize and simplify data governance, security, and workflow management for all data across multicloud and hybrid environments.
  • Imperva DSF integrates Imperva Sonar and a deep portfolio of industry-leading and mission critical Imperva Data Security products and technologies.
  • Imperva Data Security Fabric enables organizations to safeguard their sensitive data while ensuring data security, compliance, and privacy, and managing digital risk while confidently moving strategic data to the cloud.
  • Data Governance: discover and classify sensitive data residing in structured, semi-structured, and unstructured data types, to operationalize security control policies.

Alpine 4 Holdings (ALPP) Subsidiary ElecJet Releases the Results from The Battery Innovation Center (BIC) On Its AX Class Solid-State Batteries

Retrieved on: 
Friday, March 25, 2022

ElecJet, earlier this month, engaged the Battery Innovation Center (BIC) in Newberry, Indiana to have a third-party verification of the specifications of its AX Class of Solid-State Batteries that ElecJet has already confirmed in its laboratory.

Key Points: 
  • ElecJet, earlier this month, engaged the Battery Innovation Center (BIC) in Newberry, Indiana to have a third-party verification of the specifications of its AX Class of Solid-State Batteries that ElecJet has already confirmed in its laboratory.
  • ElecJet has engaged the BIC to verify the results of the G-AX Class as well, later in 2022.
  • The AX Battery Class is a Ceramic Oxide solid-state battery and comes in the form of a 31Ah Solid-State Battery and a 10Ah Solid-State Battery.
  • All of the AX and G-AX Classes are true solid-state batteries and are not semi solid-state batteries.

Alpine 4 Holdings (ALPP) Subsidiary Vayu Aerospace Corporation and ENSCO Enter into a Drone Sales Agreement for Its US-1 Long Flight Duration Drone

Retrieved on: 
Wednesday, March 23, 2022

Vayu's President, TK Eppley commented, "When I was hired 9 months ago, I was tasked with building out a drone production facility.

Key Points: 
  • Vayu's President, TK Eppley commented, "When I was hired 9 months ago, I was tasked with building out a drone production facility.
  • It's incredibly gratifying to be fulfilling orders and to be doing business with a company of Ensco's caliber."
  • Kent Wilson, CEO of Alpine 4, had this to say, "TK and his team have done a great job professionalizing the airframes Vayu offers.
  • ENSCO is a provider of engineering, science, and advanced technology equipment for the defense, security, transportation, and aerospace industries.

DRONEDEK and Alpine 4 Holdings Subsidiary, Vayu Aerospace Corporation, Partner to Create a New Ecosystem for Drone Delivery

Retrieved on: 
Monday, March 21, 2022

INDIANAPOLIS, March 21, 2022 /PRNewswire/ -- DRONEDEK, known for its "mailbox of the future," is working with Alpine 4 Holdings subsidiary Vayu Aerospace Corporation (Vayu) to create a new last-mile ecosystem in drone package delivery.

Key Points: 
  • Fortune Business Insights estimates the overall drone package delivery space to be worth $51 billion by 2028 .
  • "Vayu Aerospace and Alpine 4 have both earned a reputation as innovative leaders in the drone delivery and manufacturing markets," O'Toole said.
  • "We're learning from one another on how to help deliver a faster, safer, and more secure drone delivery experience for everyone."
  • Kent Wilson, CEO of Alpine 4 Holdings commented, "We are excited to partner with Dan and his team.

Liebherr and Tula Join Research Activities

Retrieved on: 
Thursday, March 10, 2022

Together, the companies carried out research on reducing greenhouse gases (GHG) and nitrogen oxides (NOX) produced by heavy-duty equipment.

Key Points: 
  • Together, the companies carried out research on reducing greenhouse gases (GHG) and nitrogen oxides (NOX) produced by heavy-duty equipment.
  • Therefore, Liebherr-Components will continue its activities in designing a proof of concept hardware for the integration of Tulas dDSF software into their engine system.
  • In the next step, Liebherr will consider the integration of the dDSF software into other engines in its portfolio.
  • "Liebherr is a forward-thinking company focusing already today on the challenges that customers around the world will face tomorrow, says Ulrich Weiss, Managing Director for Research and Development of Combustion Engines at Liebherr Machines Bulle SA.