Zileuton

Akari Advances Lung Program with Inhaled Nomacopan Focused on Early Treatment of Severe Exacerbations in Lung Diseases

Retrieved on: 
Wednesday, January 26, 2022

We are therefore delighted to be working with Inhalation Biosciences AB to further develop an inhaled drug delivery system for nomacopan.

Key Points: 
  • We are therefore delighted to be working with Inhalation Biosciences AB to further develop an inhaled drug delivery system for nomacopan.
  • This points to the potential for nomacopan, a potent inhibitor of both C5 and LTB4, as a focused treatment for disease exacerbations across multiple severe lung disorders, including severe asthma, COPD and COVID-pneumonia.
  • Therefore, to optimize the potential clinical utility of nomacopan, Akari is now in development of an inhaled formulation of nomacopan with Inhalation Sciences AB.
  • Akari is focused on developing nomacopan for treating exacerbations with a patient-friendly inhaled formulation for early intervention to prevent the potentially serious clinical consequences.

Novateur Ventures explores new strategy to reduce the hyperinflammatory response caused by COVID-19

Retrieved on: 
Thursday, August 6, 2020

VANCOUVER, British Columbia, Aug. 06, 2020 (GLOBE NEWSWIRE) -- A novel strategy has been developed by Novateur Ventures , which provides new hope in battle against COVID-19.

Key Points: 
  • VANCOUVER, British Columbia, Aug. 06, 2020 (GLOBE NEWSWIRE) -- A novel strategy has been developed by Novateur Ventures , which provides new hope in battle against COVID-19.
  • The study titled A Novel Strategy to Mitigate the Hyperinflammatory Response to COVID-19 by Targeting Leukotrienes was published in Frontiers in Pharmacology , a leading peer-reviewed journal.
  • The strategy co-authored by Ali Ardakani, Founder & Managing Director at Novateur Ventures, and Dr. Colin D. Funk (Queen's University, Kingston) analyzes lipid mediators, known as leukotrienes, as the cause for hyperinflammatory response manifested in severe COVID-19 cases.
  • The proposed zileuton/montelukast combination could readily be added in this setting, with the goal to switch off the hyper-inflammatory response.