Bile acid malabsorption

NGM Bio Announces New Clinical Data from Ongoing Trial of NGM707 in Advanced Solid Tumors and Outlines Evolved Strategy for Aldafermin and NGM120 to Focus on Rare Conditions with Significant Unmet Need

Retrieved on: 
Tuesday, January 9, 2024

NGM Bio also outlined its strategy to evolve clinical development of its product candidates aldafermin and NGM120 to focus on rare conditions characterized by significant unmet need.

Key Points: 
  • NGM Bio also outlined its strategy to evolve clinical development of its product candidates aldafermin and NGM120 to focus on rare conditions characterized by significant unmet need.
  • Recent landmark genetic research confirmed the link between this rare, devastating condition experienced during pregnancy to higher levels of GDF15.
  • Given our deep expertise in GDF15 biology, we believe we are well positioned to potentially pursue this indication for NGM120.
  • NGM Bio previously reported data from a randomized, double-blind, placebo-controlled Phase 2 study of aldafermin for the treatment of PSC.

NGM Bio Announces Multiple Aldafermin Presentations at Upcoming AASLD The Liver MeetingĀ®, including Late-Breaking Oral Presentation of 24-Week Phase 2 Study (Cohort 4) of Aldafermin in Patients with NASH

Retrieved on: 
Wednesday, November 4, 2020

The presentation will include detailed findings from the 24-week Phase 2 study in subgroups of patients who had stage 2 (F2) or stage 3 (F3) liver fibrosis at baseline.

Key Points: 
  • The presentation will include detailed findings from the 24-week Phase 2 study in subgroups of patients who had stage 2 (F2) or stage 3 (F3) liver fibrosis at baseline.
  • This presentation will report on comprehensive data from the 24-week Phase 2 study, including new analyses of C4, a marker of bile acid synthesis, as well as serum bile acid changes from the study.
  • NGM has evaluated this wholly-owned therapeutic in over 500 healthy volunteers and patients across multiple liver and metabolic diseases, including more than 200 NASH patients.
  • At NGM, we aspire to operate one of the most productive research and development engines in the biopharmaceutical industry, with multiple programs in clinical development.

Bile Duct Cancer in Europe: 2020 Market and Competitive Landscape Study

Retrieved on: 
Friday, July 3, 2020

DUBLIN, July 3, 2020 /PRNewswire/ -- The "Europe Bile Duct Cancer Market and Competitive Landscape - 2020" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • DUBLIN, July 3, 2020 /PRNewswire/ -- The "Europe Bile Duct Cancer Market and Competitive Landscape - 2020" report has been added to ResearchAndMarkets.com's offering.
  • This report provides comprehensive insights into the Bile Duct Cancer pipeline, epidemiology, market valuations, drug sales, market forecast, drug forecasts, and market shares.
  • This research covers the following: Bile Duct Cancer treatment options, Bile Duct Cancer late stage clinical trials pipeline, Bile Duct Cancer prevalence by countries, Bile Duct Cancer market size and forecast by countries, key market events and trends, drug sales and forecast by countries, and market shares by countries.
  • Bile Duct Cancer pipeline: Find out drugs in clinical trials for the treatment of Bile Duct Cancer by development phase 3, phase 2, and phase 1, by pharmacological class and company
    Bile Duct Cancer drugs: Identify key drugs marketed and prescribed for Bile Duct Cancer in the US, including trade name, molecule name, and company
    Bile Duct Cancer drugs sales: Find out the sales value for Bile Duct Cancer drugs by countries
    Bile Duct Cancer market valuations: Find out the market size for Bile Duct Cancer drugs in 2019 by countries.

European Bile Duct Cancer Market Review 2016-2019 and Forecast 2020-2024 - ResearchAndMarkets.com

Retrieved on: 
Tuesday, June 30, 2020

This report provides comprehensive insights into the Bile Duct Cancer pipeline, epidemiology, market valuations, drug sales, market forecast, drug forecasts, and market shares.

Key Points: 
  • This report provides comprehensive insights into the Bile Duct Cancer pipeline, epidemiology, market valuations, drug sales, market forecast, drug forecasts, and market shares.
  • This research analyzes and forecasts the Bile Duct Cancer market size and drug sales.
  • This research covers the following: Bile Duct Cancer treatment options, Bile Duct Cancer late stage clinical trials pipeline, Bile Duct Cancer prevalence by countries, Bile Duct Cancer market size and forecast by countries, key market events and trends, drug sales and forecast by countries, and market shares by countries.
  • Bile Duct Cancer pipeline: Find out drugs in clinical trials for the treatment of Bile Duct Cancer by development phase 3, phase 2, and phase 1, by pharmacological class and company
    Bile Duct Cancer drugs: Identify key drugs marketed and prescribed for Bile Duct Cancer in the US, including trade name, molecule name, and company
    Bile Duct Cancer drugs sales: Find out the sales value for Bile Duct Cancer drugs by countries
    Bile Duct Cancer market valuations: Find out the market size for Bile Duct Cancer drugs in 2019 by countries.