Aeolus

Aiolos Bio Strengthens and Expands Leadership Team with Key Appointments

Retrieved on: 
Tuesday, December 12, 2023

“We are delighted to welcome René and Tapan as key members of our leadership team at this exciting time for the Company as we prepare to initiate a Phase 2 clinical trial for our lead drug candidate, AIO-001, in moderate-to-severe asthma patients,” said Khurem Farooq, Co-Founder and Chief Executive Officer of Aiolos Bio.

Key Points: 
  • “We are delighted to welcome René and Tapan as key members of our leadership team at this exciting time for the Company as we prepare to initiate a Phase 2 clinical trial for our lead drug candidate, AIO-001, in moderate-to-severe asthma patients,” said Khurem Farooq, Co-Founder and Chief Executive Officer of Aiolos Bio.
  • “I’m thrilled to be joining the talented team at Aiolos Bio,” said Dr. Van der Merwe.
  • We look forward to presenting and publishing data in 2024.” Dr. Van der Merwe will join Aiolos Bio effective January 2,2024.
  • He joins Aiolos Bio from Bain Capital Life Sciences where he led and managed investments across therapeutic areas.

Aiolos Bio Launches with $245 Million Series A Investment to Advance Development of Novel, Phase 2-Ready TSLP Antibody

Retrieved on: 
Tuesday, October 24, 2023

Aiolos launches with an oversubscribed $245 million Series A investment co-led by Atlas Venture, Bain Capital Life Sciences, Forbion, and Sofinnova Investments with additional investment from RA Capital Management (collectively the “Investor Group”).

Key Points: 
  • Aiolos launches with an oversubscribed $245 million Series A investment co-led by Atlas Venture, Bain Capital Life Sciences, Forbion, and Sofinnova Investments with additional investment from RA Capital Management (collectively the “Investor Group”).
  • The Company will advance its lead drug candidate, AIO-001, into a Phase 2 clinical trial in moderate-to-severe asthma patients and is actively evaluating additional development opportunities.
  • AIO-001 is an anti-thymic stromal lymphopoietin (TSLP) monoclonal antibody that has the potential to be administered only twice per year due to its differentiated potency and long half-life.
  • Aiolos Bio acquired exclusive rights for global development and commercialization of the drug outside of greater China from Jiangsu Hengrui Pharmaceuticals Co., Ltd (“Hengrui”) in August 2023.

LeoLabs Provides Tracking Support for ESA's Historic Assisted Satellite Reentry

Retrieved on: 
Monday, August 14, 2023

MENLO PARK, Calif., Aug. 14, 2023 /PRNewswire/ -- LeoLabs, the leading commercial provider of Space Traffic Management (STM) and Space Situational Awareness (SSA) services, today shared their support for the European Space Agency's (ESA) successful assisted reentry of Aeolus, an Earth observation satellite, over Antarctica on 28 July 2023.  

Key Points: 
  • The company provided reliable tracking of ESA's Aeolus satellite during the semi-controlled reentry, illustrating LeoLabs' tracking capabilities in a high-drag environment.
  • This assisted reentry was considered the "first-of-its-kind" because the satellite, named Aeolus, was not designed for a controlled reentry when launched by ESA in 2018.
  • LeoLabs supported this mission as a tracking partner, receiving ephemeris data prior to and after each maneuver from ESA Mission Control.
  • This partnership served as a successful test of LeoLabs' object tracking capabilities in very low Earth orbit (VLEO), which includes altitudes below 400 km.

Bermuda Climate Summit Attracts Companies with Approximately $4 Trillion of Assets

Retrieved on: 
Thursday, June 29, 2023

The second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency, in partnership with KBRA, attracted 119 separate companies with a total combined assets under management of ­~$4.16 trillion.

Key Points: 
  • The second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency, in partnership with KBRA, attracted 119 separate companies with a total combined assets under management of ­~$4.16 trillion.
  • The Bermuda Climate Summit attracted 335 delegates, including 101 from overseas, and not only ensured Bermuda remained globally well regarded as a climate thought-leader, but also delivered on its theme to create business solutions, policy, and jobs of the future.
  • We also thank our eight local environmental charities – Bermuda Aquarium Museum and Zoo (BAMZ) , Bermuda Audubon Society , Bermuda Institute for Ocean Sciences (BIOS) , Bermuda National Trust (BNT) , Bermuda Ocean Prosperity Programme (BOPP) , Beyond Plastic , Keep Bermuda Beautiful (KBB ) and Living Reefs Foundation .
  • Special thanks to Aspen for supporting the planting of one tree per Bermuda Climate Summit delegate via our charity partners.

Eight Local Environmental Charities to be Highlighted at Bermuda Climate Summit

Retrieved on: 
Thursday, June 22, 2023

Eight local environmental charities will participate in important climate risk solution conversations at the second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency (BDA), in partnership with KBRA.

Key Points: 
  • Eight local environmental charities will participate in important climate risk solution conversations at the second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency (BDA), in partnership with KBRA.
  • Bermuda Aquarium Museum and Zoo (BAMZ) , Bermuda Audubon Society , Bermuda Institute for Ocean Sciences (BIOS) , Bermuda National Trust (BNT) , Bermuda Ocean Prosperity Programme (BOPP) , Beyond Plastic , Keep Bermuda Beautiful (KBB ) and Living Reefs Foundation , will all provide delegates with information about their stewardship of Bermuda’s environment and natural resources.
  • Dr. Ian Walker, Principal Curator, Bermuda Aquarium, Museum & Zoo (BAMZ) said, “The Bermuda Zoological Society (BZS) has been teaching about Bermuda’s environment for over four decades.
  • Cheryl Ann Mapp, Bermuda Ocean Prosperity Programme (BOPP) Blue Economy Specialist said, “BOPP is honoured to be invited again to participate in the second annual Bermuda Climate Summit.

Kymera Therapeutics’ STAT3 Degrader KT-333 and IRAKIMiD Degrader KT-413 Demonstrate Desired Target Knockdown and Safety with Continued Dose Escalation in Ongoing Phase I Clinical Trials

Retrieved on: 
Wednesday, June 14, 2023

WATERTOWN, Mass., June 14, 2023 (GLOBE NEWSWIRE) -- Kymera Therapeutics, Inc. (NASDAQ: KYMR), a clinical-stage biopharmaceutical company advancing targeted protein degradation (TPD) to deliver novel small molecule protein degrader medicines, today shared new data demonstrating that its oncology programs KT-333 and KT-413 continue to demonstrate robust dose-dependent target knockdown in ongoing Phase 1a dose escalation clinical trials, with no dose limiting toxicities (DLTs) observed. The KT-333 clinical data will be presented in a poster at the International Conference on Malignant Lymphoma (ICML) on June 16, 2023, in Lugano, Switzerland.

Key Points: 
  • The KT-333 clinical data will be presented in a poster at the International Conference on Malignant Lymphoma (ICML) on June 16, 2023, in Lugano, Switzerland.
  • “We are proud and excited to be the first company to have shown clinical translation of our degraders’ profiles across three programs and across multiple diseases and indications.
  • Data reported from the 3 completed dose levels (DL1-3) found:
    Plasma exposure increased with dose, reaching levels close to those predicted to be efficacious.
  • KT-413 achieved dose-dependent degradation of up to 70% IRAK4 and 96-100% Ikaros and Aiolos in PBMC after a single dose.

Global Climate Leaders Aim to Create Climate Risk Solutions at Bermuda Climate Summit

Retrieved on: 
Tuesday, June 13, 2023

With the effects of climate change ever more apparent, the stage is set for global experts to devise climate risk solutions at the second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency (BDA), in partnership with KBRA.

Key Points: 
  • With the effects of climate change ever more apparent, the stage is set for global experts to devise climate risk solutions at the second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency (BDA), in partnership with KBRA.
  • Joshua Rosenberg, Chief Risk Officer, Federal Reserve Bank of New York, alongside past BDA-Chair, Stephen Weinstein, will bring the event to a close on June 27.
  • After months of planning, we are so excited about the line-up of expert speakers that will come together here at our Bermuda Climate Summit.
  • Our supporting sponsors are Butterfield, HSBC and Ocean-Based Climate Solutions, Inc. Our media partners are Bermuda:Re+ILS, Climate and Capital Media, Insurance Insider, and The Insurer.

Deputy Premier Roban to Kick Off Bermuda Climate Summit, June 26-27

Retrieved on: 
Thursday, May 11, 2023

Walter Roban, JP, MP will kick off the second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency (BDA), in partnership with KBRA on June 26.

Key Points: 
  • Walter Roban, JP, MP will kick off the second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency (BDA), in partnership with KBRA on June 26.
  • The Deputy Premier will discuss Bermuda’s key attributes as the world’s climate risk finance capital in a keynote seaside chat with Mark Baker, President & CEO, KBRA.
  • David Hart, BDA, CEO said, “The theme of this year’s event is ‘Bermuda - Climate Central’ and we are honoured to have Deputy Premier Roban join us to open the 2023 Bermuda Climate Summit.
  • We are equally pleased to have so many leading climate experts across different fields coming to Bermuda to engage with our audience on why climate is such an important topic.

New York Federal Reserve Chief to Give Keynote at Bermuda Climate Summit, June 26-27

Retrieved on: 
Tuesday, April 18, 2023

The keynote address at the second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency (BDA), in partnership with KBRA, will be given by Joshua Rosenberg, Chief Risk Officer, Federal Reserve Bank of New York on June 27.

Key Points: 
  • The keynote address at the second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency (BDA), in partnership with KBRA, will be given by Joshua Rosenberg, Chief Risk Officer, Federal Reserve Bank of New York on June 27.
  • David Hart, BDA, CEO said, “We are so excited to have such leading climate experts speak to our second annual Bermuda Climate Summit.
  • They will share why climate is such an important topic and how Bermuda is the perfect place to develop climate risk solutions.
  • Head of Sustainability, Convex, Andrew MacFarlane, Head of Climate, AXA XL, a Division of AXA, and Andrew Smith, Chief Risk and Sustainability Officer at Conduit Re.

BDA to Hold Second Annual Bermuda Climate Summit, June 26-27

Retrieved on: 
Thursday, April 6, 2023

As the world seeks ways to confront our planet’s biggest challenge, climate change, Bermuda is uniquely positioned to be a global leader in providing climate risk strategies and solutions.

Key Points: 
  • As the world seeks ways to confront our planet’s biggest challenge, climate change, Bermuda is uniquely positioned to be a global leader in providing climate risk strategies and solutions.
  • The second annual Bermuda Climate Summit, presented by the Bermuda Business Development Agency (BDA), in partnership with KBRA, will showcase not just the seriousness of the threat, but also the attributes and innovative spirit Bermuda can bring to the table to help partners across to world rise to meet this global crisis.
  • Bermuda has a long history of providing financial solutions that mitigate the negative impact of crises.
  • The BDA encourages direct investment and helps companies start up, re-locate, or expand their operations in our premier jurisdiction.