Tempest

Tempest Reports New Preclinical Data for TPST-1120 in RCC at the AACR Annual Meeting

Retrieved on: 
Tuesday, April 9, 2024

These new data further support the clinical benefit observed in the TPST-1120 Phase 1 data presented in an oral presentation at ASCO 2022.

Key Points: 
  • These new data further support the clinical benefit observed in the TPST-1120 Phase 1 data presented in an oral presentation at ASCO 2022.
  • “Preclinical data presented at AACR further demonstrate that TPST-1120 has the potential to positively transform the tumor microenvironment and expand the activity of anti-tumor immunity in kidney cancer,” said Sam Whiting, M.D., Ph.D., chief medical officer and head of R&D at Tempest.
  • In preclinical models of renal cell carcinoma (RCC), treatment with TPST-1120 reduced tumor growth by 52%-56% as monotherapy.
  • Additional improvement in anti-cancer activity was demonstrated in combination treatment with standard first-line RCC cabozantinib or anti-PD1 therapy, where tumor inhibition was 81% and 74%, respectively.

Tempest Presents New Data at the SITC 2024 Spring Scientific Meeting Supporting Potent Anti-tumor Activity of TPST-1120 in Multiple Cancer Types

Retrieved on: 
Tuesday, March 12, 2024

BRISBANE, Calif., March 12, 2024 (GLOBE NEWSWIRE) -- Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company developing first-in-classi targeted and immune-mediated therapeutics to fight cancer, today announced a poster presentation at the Society for Immunotherapy of Cancer (SITC) 2024 Spring Scientific Meeting highlighting preclinical data showing potent anti-tumor activity in several cancer models treated with TPST-1120 alone or with immune checkpoint inhibitors.

Key Points: 
  • BRISBANE, Calif., March 12, 2024 (GLOBE NEWSWIRE) -- Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company developing first-in-classi targeted and immune-mediated therapeutics to fight cancer, today announced a poster presentation at the Society for Immunotherapy of Cancer (SITC) 2024 Spring Scientific Meeting highlighting preclinical data showing potent anti-tumor activity in several cancer models treated with TPST-1120 alone or with immune checkpoint inhibitors.
  • “Data presented at the SITC Spring Scientific Meeting bolster our mechanistic understanding of PPARα blockade in cancer patients and reinforce a basis for the ongoing late-stage clinical development of TPST-1120,” said Sam Whiting, M.D., Ph.D., chief medical officer and head of R&D at Tempest.
  • Clinical response and biomarker findings support that inhibition of PPARα may be an effective therapeutic strategy for the treatment of cancer.
  • These findings complement positive data reported in October 2023 from a global randomized phase 1b/2 study of TPST-1120 in combination with atezolizumab and bevacizumab in first-line patients with advanced HCC.

Firestorm Labs and Congresswoman Sara Jacobs (CA-51) Celebrate Opening of State-of-the-Art Headquarters in San Diego

Retrieved on: 
Wednesday, April 3, 2024

SAN DIEGO, April 3, 2024 /PRNewswire/ -- Yesterday, Firestorm Labs, a defense technology startup spearheading expeditionary manufacturing of Unmanned Aerial Systems (UAS), proudly celebrated the grand opening of its state-of-the-art, 14,000 square foot headquarters in Kearny Mesa, San Diego, California.

Key Points: 
  • SAN DIEGO, April 3, 2024 /PRNewswire/ -- Yesterday, Firestorm Labs, a defense technology startup spearheading expeditionary manufacturing of Unmanned Aerial Systems (UAS), proudly celebrated the grand opening of its state-of-the-art, 14,000 square foot headquarters in Kearny Mesa, San Diego, California.
  • During her keynote remarks, Congresswoman Jacobs congratulated Firestorm, saying"I am so glad that Firestorm is opening its new headquarters in San Diego, creating jobs, spurring new investment opportunities, and driving forward innovation to help our troops and allies identify and neutralize threats."
  • Representative Jacobs and guests were given special access to explore Firestorm's technology and witness their commitment to tackling evolving defense needs.
  • "Firestorm is dedicated to delivering state-of-the-art defense capabilities that meet the challenges of today's complex security landscape head on," said Magy.

Tempest to Present at the 35th Annual Piper Sandler Healthcare Conference

Retrieved on: 
Monday, November 20, 2023

BRISBANE, Calif., Nov. 20, 2023 (GLOBE NEWSWIRE) -- Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage oncology company developing first-in-classi therapeutics that combine both targeted and immune-mediated mechanisms, today announced that management will participate in a fireside chat at the 35th Annual Piper Sandler Healthcare Conference on Tuesday, November 28, 2023 at 3:00 p.m.

Key Points: 
  • BRISBANE, Calif., Nov. 20, 2023 (GLOBE NEWSWIRE) -- Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage oncology company developing first-in-classi therapeutics that combine both targeted and immune-mediated mechanisms, today announced that management will participate in a fireside chat at the 35th Annual Piper Sandler Healthcare Conference on Tuesday, November 28, 2023 at 3:00 p.m.
  • ET.
  • To access the live or archived recording of the discussion, please visit the investor section of the Tempest website at https://ir.tempesttx.com .

TYAN Upgrades HPC, AI and Data Center Solutions with the Power of 5th Gen Intel® Xeon® Scalable Processors

Retrieved on: 
Thursday, December 14, 2023

Growing and excelling with workload-optimized performance, 5th Gen Intel Xeon delivers more compute power and faster memory within the same power envelope as the previous generation.

Key Points: 
  • Growing and excelling with workload-optimized performance, 5th Gen Intel Xeon delivers more compute power and faster memory within the same power envelope as the previous generation.
  • "By harnessing the capabilities of Intel's new Xeon CPUs, TYAN's 5th-Gen Intel Xeon-supported solutions are designed to handle the intense demands of HPC, data centers, and AI workloads.
  • In addition, TYAN offers Thunder HX FT65T-B7130 , the other deskside HPC platform providing balanced CPU/GPU computing architecture with dual 5th Generation Intel Xeon Scalable processor support.
  • In addition to server systems, TYAN provides upgraded motherboard solutions based on the latest 5th Gen Intel Xeon Scalable processor.

TYAN Upgrades HPC, AI and Data Center Solutions with the Power of 5th Gen Intel® Xeon® Scalable Processors

Retrieved on: 
Thursday, December 14, 2023

Growing and excelling with workload-optimized performance, 5th Gen Intel Xeon delivers more compute power and faster memory within the same power envelope as the previous generation.

Key Points: 
  • Growing and excelling with workload-optimized performance, 5th Gen Intel Xeon delivers more compute power and faster memory within the same power envelope as the previous generation.
  • "By harnessing the capabilities of Intel's new Xeon CPUs, TYAN's 5th-Gen Intel Xeon-supported solutions are designed to handle the intense demands of HPC, data centers, and AI workloads.
  • In addition, TYAN offers Thunder HX FT65T-B7130 , the other deskside HPC platform providing balanced CPU/GPU computing architecture with dual 5th Generation Intel Xeon Scalable processor support.
  • In addition to server systems, TYAN provides upgraded motherboard solutions based on the latest 5th Gen Intel Xeon Scalable processor.

Tempest Announces Leadership Transition to Drive Future Growth

Retrieved on: 
Tuesday, December 5, 2023

With over 20 years of experience in the telecommunications sector, Joe Hart brings a proven track record of leadership, innovation, and operational excellence to Tempest.

Key Points: 
  • With over 20 years of experience in the telecommunications sector, Joe Hart brings a proven track record of leadership, innovation, and operational excellence to Tempest.
  • Tempest also expresses its gratitude to Dan Firestone, outgoing Chief Operating Officer, for his 18 years of leadership and dedicated service.
  • "We are excited about the wealth of experience and leadership that Joe brings to Tempest," said Jessica Firestone, Founder and President.
  • "This strategic transition positions us for continued innovation, growth, and success in the dynamic telecom industry."

Tempest Reports Third Quarter 2023 Financial Results and Provides Business Update

Retrieved on: 
Wednesday, November 8, 2023

BRISBANE, Calif., Nov. 08, 2023 (GLOBE NEWSWIRE) -- Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage oncology company developing first-in-classi therapeutics that combine both targeted and immune-mediated mechanisms, today reported financial results for the third quarter ended September 30, 2023 and provided a corporate update.

Key Points: 
  • BRISBANE, Calif., Nov. 08, 2023 (GLOBE NEWSWIRE) -- Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage oncology company developing first-in-classi therapeutics that combine both targeted and immune-mediated mechanisms, today reported financial results for the third quarter ended September 30, 2023 and provided a corporate update.
  • The results for the quarter-to-date period are preliminary, unaudited and are not necessarily indicative of the results that may be expected for the full quarter or year ending December 31, 2023.
  • Research and development expenses for the quarter ended September 30, 2023 were $4.2 million compared to $6.0 million for the same period in 2022.
  • General and administrative expenses for the quarter ended September 30, 2023 were $2.4 million compared to $2.8 million for the same period in 2022.

JLab’s New Epic Lab Edition Earbuds Are Its Most Premium True Wireless Product To Date And The First Earbuds Featuring The Knowles Preferred Listening Response Curve

Retrieved on: 
Tuesday, November 7, 2023

The Epic Lab Edition is the first true wireless earbuds to feature the Knowles Preferred Listening Response Curve (Knowles Curve), a treble expanded sound signature designed with extensive feedback from a broad range of music listeners.

Key Points: 
  • The Epic Lab Edition is the first true wireless earbuds to feature the Knowles Preferred Listening Response Curve (Knowles Curve), a treble expanded sound signature designed with extensive feedback from a broad range of music listeners.
  • "JLab’s Epic Lab Edition elevates our portfolio of audio products with new technologies, including specialized balanced armature drivers to match the Knowles Preferred Listening Response Curve, something no other brand has right now."
  • A suite of premium features along with the hybrid dual-driver design are included in the Epic Lab Edition.
  • The JLab Epic Lab earbuds are available for pre-order at www.jlab.com/products/epic-lab-edition-earbuds , with an estimated ship date of mid-November.

Australian theatre companies are shunning Shakespeare. A much-needed break, or a mistake?

Retrieved on: 
Wednesday, October 18, 2023

In 2024 not one mainstage theatre company in Australia will perform Shakespeare.

Key Points: 
  • In 2024 not one mainstage theatre company in Australia will perform Shakespeare.
  • The only exception will be Bell Shakespeare.
  • Theatre makers such as Lachlan Philpott, Nakkiah Lui and Andrew Bovell have been calling for less Shakespeare and more new work since the mid-2010s.

A forum for conversations

    • He is important because we have, for 400 years, made him important, using his work to have rich conversations about identity, truth, meaning and morality.
    • These conversations are worth participating in.
    • The fact that none of these companies will perform Shakespeare next year suggests a decline in engagement with the canon outside of adaptations.
    • We risk understanding ourselves merely through the lens of now, rather than enriching our present through discussion with our history.

Critical engagement

    • We are not restricted to either using Shakespeare as a sock puppet to voice our own ideas, or ignoring him altogether.
    • Like any fruitful conversation, it means listening, sitting with discomfort, learning, recognising what still speaks to us, and responding to what doesn’t.
    • Conversing with Shakespeare does not mean smoothing over problems or forcing him to agree with us.
    • The scenes in which Shylock is forced to surrender both his property and his faith were jarringly and uncomfortably melancholy.

Talking back to history

    • What are we doing differently today, and what should we be doing differently?
    • Nuanced, two-way conversations with our cultural history are vital to progress.
    • It means learning from, questioning, and talking back to our history.