Lassen

Lassen Therapeutics Presents Preclinical Data on LASN01, an Anti-IL-11 Receptor Antibody in Development for Treatment of Thyroid Eye Disease at the American Thyroid Association 2023 Annual Meeting

Retrieved on: 
Monday, October 2, 2023
Biotechnology, Other Health, Health, General Health, Pharmaceutical, Optical, Oncology, Other Science, Research, Science, Clinical Trials, American Thyroid Association, Therapy, ATA, Cancer, Cell proliferation, Hyaluronic acid, MBA, Doctor of Philosophy, Graves' ophthalmopathy, OF, Teprotumumab, Patient, Annual general meeting, IPF, Idiopathic pulmonary fibrosis, TED, Vaccine, Lassen

Lassen Therapeutics , a clinical stage biotechnology company developing first-in-class antibody therapeutics targeting interleukin-11 receptor (IL-11R; LASN01) as a potential treatment for fibro-inflammatory diseases including thyroid eye disease (TED) and idiopathic pulmonary fibrosis (IPF), and interleukin-18 binding protein (IL-18BP; LASN500), as a potential treatment for cancer, presented new preclinical data on LASN01, for treatment of TED, at the American Thyroid Association (ATA) Annual Meeting held in Washington DC, September 27 through October 1, 2023.

Key Points: 
  • Lassen Therapeutics , a clinical stage biotechnology company developing first-in-class antibody therapeutics targeting interleukin-11 receptor (IL-11R; LASN01) as a potential treatment for fibro-inflammatory diseases including thyroid eye disease (TED) and idiopathic pulmonary fibrosis (IPF), and interleukin-18 binding protein (IL-18BP; LASN500), as a potential treatment for cancer, presented new preclinical data on LASN01, for treatment of TED, at the American Thyroid Association (ATA) Annual Meeting held in Washington DC, September 27 through October 1, 2023.
  • “We continue our work in demonstrating the potential benefit of LASN01 in orbital fibroblasts, the relevant cell type for thyroid eye disease,” said Maria Fardis, PhD, MBA, CEO at Lassen.
  • “In preclinical studies, LASN01 led to the suppression of cell proliferation and hyaluronan secretion from primary TED orbital fibroblasts, in addition to demonstrating anti-fibrotic activity.
  • The effects of LASN01 on HA release and OF proliferation were comparable to the approved anti-IGF-1R antibody, teprotumumab, indicating that LASN01 should be further investigated as a potential new therapeutic agent for the treatment of TED.

Lassen Therapeutics Presents New Data on LASN01 for the Treatment of Idiopathic Pulmonary Fibrosis and Thyroid Eye Disease at the European Respiratory Society (ERS) and European Thyroid Association (ETA) Annual Meetings

Retrieved on: 
Monday, September 11, 2023
Science, Biotechnology, Research, Pharmaceutical, Optical, Oncology, Health, Clinical Trials, Well, STAT3, Therapy, Phosphorylation, Half-life, HA, Cancer, Cell proliferation, MBA, Doctor of Philosophy, ERS, Graves' ophthalmopathy, ETA, Teprotumumab, Patient, European Respiratory Society, Extracellular matrix, IPF, International Congress on Tuberculosis, Idiopathic pulmonary fibrosis, VI, TED, Pharmaceutical industry, Vaccine, Lassen

“Toward that, we have made significant progress in generating data with LASN01 in both clinical and nonclinical settings.

Key Points: 
  • “Toward that, we have made significant progress in generating data with LASN01 in both clinical and nonclinical settings.
  • We have completed our Phase 1 single ascending and multiple ascending dose cohorts and presented data from our healthy volunteer study at ERS.
  • We also presented our preclinical data in a TED fibro-inflammatory disease model using orbital fibroblasts (OF) at ETA.
  • Furthermore, LASN01 worked effectively in combination with teprotumumab, an approved agent for the treatment of TED, in inhibiting HA release.

AUDO COPENHAGEN DEBUTS GLOBALLY

Retrieved on: 
Thursday, June 1, 2023
Designer Brands, Lighting, Audo, B&B Italia, Partnership, MENU, Interior design, Lassen, Flos

MENU and by Lassen merge globally and debut as Audo Copenhagen.

Key Points: 
  • MENU and by Lassen merge globally and debut as Audo Copenhagen.
  • From June 1st, design enthusiasts, professionals and customers worldwide will discover many of their favorite furniture, lighting designs and accessories within one new design house: Audo Copenhagen.
  • Audo Copenhagen reflects both a century of Danish design tradition and a modern, global outlook that will continually expand and evolve.
  • With its ethos inspired by The Audo, MENU and by Lassen and its operations in partnership with Design Holding, Audo Copenhagen strives to become a leading player in global luxury design.

California housing affordability rises to highest level in a year during first-quarter 2023 as home prices ebb and the cost of borrowing dips, C.A.R. reports

Retrieved on: 
Tuesday, May 16, 2023
Insurance, San Francisco Bay Area, Housing, HAI, Professional, Tax, PITI, Index, Sundanese traditional house, Projection, Organization, Federal Reserve, House, LOS, Video game, Property management, Health insurance, Tourism, Lassen

LOS ANGELES, May 16, 2023 /PRNewswire/ -- Retreating home prices and slightly lower interest rates improved the outlook for more California homebuyers in the first quarter of 2023, as the state's housing affordability rose to the highest level in a year, the CALIFORNIA ASSOCIATION OF REALTORS® (C.A.R.) said today.

Key Points: 
  • The first-quarter 2023 figure is less than half of the affordability index peak of 56 percent in the first quarter of 2012.
  • With interest rates near the highest level in the past 16 years, housing affordability will remain a challenge for many homebuyers in the coming quarters.
  • Housing affordability declined the most on a year-over-year basis in Kings County, falling 18 points in first-quarter 2023.
  • Elevated mortgage rates, along with higher home prices, continued to be the primary factors for the plunge in affordability in most of these counties.

Lassen Therapeutics Appoints Maria Fardis, Ph.D., MBA, as Chief Executive Officer

Retrieved on: 
Thursday, May 4, 2023
Biotechnology, Health, Pharmaceutical, Optical, Clinical Trials, Gilead Sciences, AACR, University, Therapy, Berkeley, Norwest Venture Partners, Cancer, MBA, Golden Gate University, Research, Pharmacyclics, AstraZeneca, Graves' ophthalmopathy, Acquisition, Patient, Growth, TED, Pharmaceutical industry, Management, Lassen, Iovance Biotherapeutics

Lassen Therapeutics , a clinical-stage biotech company developing first-in-class antibody therapeutics targeting interleukin-11 receptor (IL-11R) and interleukin-18 binding protein (IL-18BP) as potential treatments for fibro-inflammatory diseases such as thyroid eye disease (TED) and for cancer, today announced the appointment of Maria Fardis, Ph.D., MBA as Chief Executive Officer.

Key Points: 
  • Lassen Therapeutics , a clinical-stage biotech company developing first-in-class antibody therapeutics targeting interleukin-11 receptor (IL-11R) and interleukin-18 binding protein (IL-18BP) as potential treatments for fibro-inflammatory diseases such as thyroid eye disease (TED) and for cancer, today announced the appointment of Maria Fardis, Ph.D., MBA as Chief Executive Officer.
  • Dr. Fardis brings more than 25 years of leadership experience in the biopharmaceutical industry to Lassen.
  • “Maria has an impressive track record of creating value for patients, the clinical community, and investors.
  • Dr. Fardis served as President and Chief Executive Officer of Iovance Biotherapeutics where she transformed the organization from an early-stage development company to one with multiple late-stage programs.

A surge in mortgage rates and elevated home prices dampened California's housing affordability in fourth-quarter 2022, C.A.R. reports

Retrieved on: 
Thursday, February 9, 2023
Organization, Insurance, Federal Reserve, House, FRM, Mono, Central Coast, Professional, Housing, Pressure, Fed, Index, Sundanese traditional house, Federal, Tax, San Francisco Bay Area, LOS, HAI, Video game, Property management, Health insurance, Lassen

California hit a peak high affordability index of 56 percent in the first quarter of 2012.

Key Points: 
  • California hit a peak high affordability index of 56 percent in the first quarter of 2012.
  • Home prices are expected to soften further in the upcoming quarter as rates remain elevated, which will continue to put some downward pressure on housing demand.
  • In the Southern California region, housing affordability fell in four counties from third-quarter 2022 and remained unchanged in two counties.
  • The surge in mortgage rates, along with elevated home prices, continued to be the primary factors for the plunge in affordability in these counties.

PLANET SAVING APP "TOO GOOD TO GO" LAUNCHES IN LOS ANGELES

Retrieved on: 
Thursday, September 29, 2022
GHG, Carbon, Drink, LOS, City, TIME, Global warming potential, Too Good To Go, Context, Climate change, Lassen Lodge, California, Environment, Tartine, Food science, Foodservice, Demographics of Los Angeles, Solution, Ice cream, Too Good, Map, Ecosystem, Restaurant, Climate, Marketing, Awareness, Multimedia, Coffee, Budget, Grocery store, Food delivery, Fast food, Renewable energy, Online shopping, Food, Lassen

LOS ANGELES, Sept. 29, 2022 /PRNewswire/ -- Too Good To Go, the world's largest surplus food marketplace, today announces its official launch in the greater Los Angeles area. The free mobile app invites everyone in LA to save delicious meals and groceries for ⅓ of the retail price, in a simple, fun and impactful way. The launch in LA follows successful launches in 12 other major US cities.

Key Points: 
  • LOS ANGELES, Sept. 29, 2022 /PRNewswire/ -- Too Good To Go , the world's largest surplus food marketplace, today announces its official launch in the greater Los Angeles area.
  • The Too Good To Go app connects users with grocery stores, restaurants, bakeries, sushi places, ice cream parlors, cafes (and many more!
  • App users can browse, reserve and pay for a Surprise Bag on the Too Good To Go app.
  • "Our team is proud to officially launch the Too Good To Go app in Los Angeles, because today more than ever our app is the best solution to different real-world issues", said Chris MacAulay, Too Good To Go US Managing Director.

Lassens, the Pioneering Organic Grocer from California, Launches Else Complete Nutrition Products in all its Stores

Retrieved on: 
Thursday, May 12, 2022
Vitamin, Toddler, Hospital, World, Health, Health food store, Infant, Toronto Stock Exchange, Facebook, Boston Children's Hospital, Instagram, Society, Nutrition, BABY, Schneider Children's Medical Center of Israel, Harvard Medical School, Medical Center, Pediatrics, Rambam Health Care Campus, GLOBE, CEO, Else, Lassen, Amazon, Tel Aviv University

"The expansion of our Clean Label, Plant-Based Nutrition products for early childhood into Lassen's outlets is important," said Hamutal Yitzhak, CEO & Co-Founder of Else Nutrition.

Key Points: 
  • "The expansion of our Clean Label, Plant-Based Nutrition products for early childhood into Lassen's outlets is important," said Hamutal Yitzhak, CEO & Co-Founder of Else Nutrition.
  • Over 40 years and eleven stores later, Oda's family and the dedicated Lassen's team continues to be driven by her original commitment to providing 100% organic produce and uncomplicated, wholesome, good-for-you products.
  • Else Nutrition GH Ltd. is an Israel-based food and nutrition company focused on developing innovative, clean, and plant-based food and nutrition products for infants, toddlers, children, and adults.
  • Else Plant-Based Complete Nutrition for Toddlers was recently ranked as the #1 Top Seller in the baby and toddler formula category on Amazon.

California housing affordability shrinks in first-quarter 2022 as home prices set record highs and interest rates rise, C.A.R. reports

Retrieved on: 
Tuesday, May 3, 2022
Sundanese traditional house, Insurance, Tax, Organization, HAI, Income, LOS, Index, Housing, Central Coast, Mono, Professional, Video game, Property management, Real estate, Health insurance, Renewable energy, Lassen, Orange, San Francisco Bay Area

The first-quarter 2022 figure is less than half of the affordability index peak of 56 percent in the first quarter of 2012.

Key Points: 
  • The first-quarter 2022 figure is less than half of the affordability index peak of 56 percent in the first quarter of 2012.
  • 's HAI measures the percentage of all households that can afford to purchase a median-priced, single-family home in California.
  • Key points from the first-quarter 2022 Housing Affordability report include:
    Compared to the previous quarter, housing affordability in the first quarter of 2022 declined in all but two of 51 counties.
  • Higher interest rates and home price surges from a year ago were primary factors that led to the drop in affordability in these counties.

YDesign Group Announces Year-End Retrospective of Industry-Defining Design Partnerships

Retrieved on: 
Wednesday, December 22, 2021
Eclipse, Tired, Niche, Original, American, Optimism, Industry, Glass, Color, CA, Lighting, VP, Merchandising, GLOBE, Interior design, Lassen

We are incredibly honored to be the partner of choice in bringing so many acclaimed designs and distinguished brands to the public, said Patricia Kittredge, VP of Merchandising at YDesign Group.

Key Points: 
  • We are incredibly honored to be the partner of choice in bringing so many acclaimed designs and distinguished brands to the public, said Patricia Kittredge, VP of Merchandising at YDesign Group.
  • While 2021 has been a year of the unexpected, YDesign Group is proud to be a leading presence in the design industry by collaborating with innovative creators who continue to define modern design.
  • ###
    YDesign Group is the leading online destination for modern and contemporary design lighting, offering a curated selection of lighting, fans, furniture and dcor from over 300 brands throughwww.lumens.comandwww.ylighting.com,including many exclusive products.
  • Based in California, YDesign Group serves consumers, trade professionals and commercial customers in the U.S. and Canada.