Axial

CHARM Therapeutics launches with a $50 million Series A financing to transform structure-based drug discovery using its proprietary DragonFold AI technology

Retrieved on: 
Thursday, June 9, 2022

CHARM Therapeutics has been created to combine these breakthroughs in 3D deep-learning with excellence in drug discovery and development, said Gary D. Glick Ph.D., Executive Chair of CHARM Therapeutics.

Key Points: 
  • CHARM Therapeutics has been created to combine these breakthroughs in 3D deep-learning with excellence in drug discovery and development, said Gary D. Glick Ph.D., Executive Chair of CHARM Therapeutics.
  • We are advancing this technology and its application to the hit discovery, hit-to-lead and lead optimization processes of small molecule drug discovery.
  • The Company is Chaired by Gary Glick, founder of IFM Therapeutics, Scorpion Therapeutics and Odyssey Therapeutics.
  • London-based CHARM Therapeutics has raised $50 million to date and is building an interdisciplinary and entrepreneurial team, combining leaders from the fields of AI and biotechnology.

Paracrine Announces Appointment of Biotech Veteran David Crean, Ph.D. to the Board of Directors

Retrieved on: 
Thursday, May 12, 2022

We are delighted to welcome David Crean to the Paracrine Board, said Christopher J. Calhoun, Chairman and CEO of Paracrine.

Key Points: 
  • We are delighted to welcome David Crean to the Paracrine Board, said Christopher J. Calhoun, Chairman and CEO of Paracrine.
  • I am happy to join Paracrines Board of Directors at this exciting time in the companys development, added David Crean, Ph.D.
  • David is also a Co-Founder and Managing General Partner of Equitos Venture Partners, a life sciences-focused investment firm with $750m of assets under management.
  • In addition, David is an investment partner with Suncoast Venture Partners and Mesa Verde Venture Partners, two micro life science seed stage & incubator venture funds.

Axial's Q1 2022 Lower Middle Market Pursuits Report Highlights the Continued Resiliency of American Lower Middle Market M&A

Retrieved on: 
Tuesday, May 3, 2022

NEW YORK, May 03, 2022 (GLOBE NEWSWIRE) -- Axial, the online M&A platform connecting buyers, advisors, and sellers of small and medium-sized businesses, has released its Lower Middle Market Pursuits report for Q1 2022.

Key Points: 
  • NEW YORK, May 03, 2022 (GLOBE NEWSWIRE) -- Axial, the online M&A platform connecting buyers, advisors, and sellers of small and medium-sized businesses, has released its Lower Middle Market Pursuits report for Q1 2022.
  • "The bad news is that the lower middle market may no longer be the best-kept secret in M&A.
  • Q1 2022 deal activity was just below the record-setting Q1 2021 high watermark.
  • As a result, lower middle market M&A dealmakers are as engaged as ever, despite rising interest rates, wobbly public markets, and a war in Europe."

Axial Therapeutics Announces Participation of its CEO, A. Stewart Campbell, in Longwood Healthcare Leaders Spring MIT Webconference

Retrieved on: 
Monday, May 2, 2022

Axial Therapeutics Inc., a clinical-stage biopharmaceutical company dedicated to the development of gut-targeted, small molecule therapeutics for neurological conditions and oncology, today announced that A. Stewart Campbell, Ph.D., chief executive officer, will participate in a panel titled Placing Patients At The Center at the Longwood Healthcare Leaders Spring MIT webconference on Wednesday, May 4, 2022.

Key Points: 
  • Axial Therapeutics Inc., a clinical-stage biopharmaceutical company dedicated to the development of gut-targeted, small molecule therapeutics for neurological conditions and oncology, today announced that A. Stewart Campbell, Ph.D., chief executive officer, will participate in a panel titled Placing Patients At The Center at the Longwood Healthcare Leaders Spring MIT webconference on Wednesday, May 4, 2022.
  • Longwood Healthcare Leaders meetings bring together leading biotech and pharma CEOs, heads of R&D, top academics, and healthcare investors for off-the-record discussions to drive transparency and collaboration in order to accelerate the translation of discoveries into medicines to help patients.
  • Axial Therapeutics is a clinical-stage biopharmaceutical company dedicated to improving the lives of people with neurological disorders and conditions.
  • The company is a scientific leader in the biological role of the microbiome-gut-brain axis and its influence on the central nervous system.

Axial Releases the Top 25 Lower Middle Market Investment Banks for Q1 2022

Retrieved on: 
Thursday, April 14, 2022

NEW YORK, April 14, 2022 (GLOBE NEWSWIRE) -- Axial, the online M&A platform connecting buyers and sellers of American small and medium-sized businesses, today released its Q1 2022 Lower Middle Market Investment Banking League Tables.

Key Points: 
  • NEW YORK, April 14, 2022 (GLOBE NEWSWIRE) -- Axial, the online M&A platform connecting buyers and sellers of American small and medium-sized businesses, today released its Q1 2022 Lower Middle Market Investment Banking League Tables.
  • "The M&A markets diverged in Q1 2022, with global M&A deal volume down 20% overall since last year's record highs, whereas the lower middle market surged more than 25% as measured by GHI," says Peter Lehrman, founder and CEO of Axial.
  • Congratulations to Q1's Top 25 lower middle market investment banks for their strong results during this period."
  • New deals marketed by Axial members increased 26% year-over-year and a total of 930 investment banks brought deals to market via the Axial platform in Q1.

Axial Therapeutics’ Scientific Founder Sarkis Mazmanian, Ph.D., to Present Research Highlighting the Gut-Brain Connection in Autism Spectrum Disorder (ASD) at TACA’s Autism Action Conference

Retrieved on: 
Tuesday, April 5, 2022

The presentation titled, Gut-Brain Axis: How substances produced by the microbiome may contribute to Autism Spectrum Disorder, will be held on Saturday, April 9 from 1:00-2:00 pm PST.

Key Points: 
  • The presentation titled, Gut-Brain Axis: How substances produced by the microbiome may contribute to Autism Spectrum Disorder, will be held on Saturday, April 9 from 1:00-2:00 pm PST.
  • This research serves as the foundation for Axial Therapeutics potential new treatment, AB-2004, for managing irritability associated with ASD in children.
  • Axial Therapeutics is a clinical-stage biopharmaceutical company dedicated to improving the lives of people with neurological disorders and conditions.
  • Axials lead product candidate is AB-2004, a molecular therapeutic in Phase 2b clinical trials for the treatment of irritability in children with autism.

Britehorn Partners Advises SolarLeadFactory on Acquisition by Enphase Energy

Retrieved on: 
Friday, March 18, 2022

DENVER, March 18, 2022 /PRNewswire/ --Britehorn Partners is pleased to announce that its client, SolarLeadFactory, has been acquired by Enphase Energy Inc. (NASDAQ: ENPH), a global energy technology company and the world's leading supplier of microinverter-based solar and battery systems.

Key Points: 
  • DENVER, March 18, 2022 /PRNewswire/ --Britehorn Partners is pleased to announce that its client, SolarLeadFactory, has been acquired by Enphase Energy Inc. (NASDAQ: ENPH), a global energy technology company and the world's leading supplier of microinverter-based solar and battery systems.
  • SolarLeadFactory has joined Enphase with the objective of substantially increasing lead volumes and conversion rates to help drive down the customer acquisition costs for installers.
  • Enphase has set out to build a digital platform for installers that incorporates tools to design, permit, install, monitor, and maintain solar and battery systems.
  • This transaction represents another successful closing for Britehorn Partners in the software and business services verticals following the closing of Action Title Reseach in December, 2021.

Axial Releases the 'Software Top 50,' Profiling the Platform's Top 50 Software Private Equity Investors & M&A Advisors

Retrieved on: 
Tuesday, March 1, 2022

NEW YORK, March 01, 2022 (GLOBE NEWSWIRE) -- Axial, the online M&A platform connecting buyers, advisors, and sellers of small and medium-sized businesses, today released its Software Top 50, profiling the platform's top 50 Lower Middle Market Software Private Equity Investors and M&A Advisors.

Key Points: 
  • NEW YORK, March 01, 2022 (GLOBE NEWSWIRE) -- Axial, the online M&A platform connecting buyers, advisors, and sellers of small and medium-sized businesses, today released its Software Top 50, profiling the platform's top 50 Lower Middle Market Software Private Equity Investors and M&A Advisors.
  • "Public market software company valuations have been battered starting in November of 2021.
  • Over 50% of Nasdaq companies are down 40% or more off their highs," says Peter Lehrman, CEO and Founder of Axial.
  • Up 26% last year, software companies represented over 40% of all sell-side technology-related deal activity on Axial.

SFW Capital Partners Announces Four Promotions

Retrieved on: 
Wednesday, March 2, 2022

Ms. Dong joined SFW Capital Partners in 2017 and she currently serves as a Board Member of SFW portfolio companies Act, Captify, Devada, RDI Technologies, and Pion.

Key Points: 
  • Ms. Dong joined SFW Capital Partners in 2017 and she currently serves as a Board Member of SFW portfolio companies Act, Captify, Devada, RDI Technologies, and Pion.
  • Mr. Sepe joined SFW Capital Partners in 2013, and he currently serves as a Board Member of SFW portfolio companies Caron, Filtec, Granite River Labs, RDI Technologies, and Pion.
  • Mr. Basu joined SFW Capital Partners in 2018 and currently works with the firm's investment in GLG, Greenshades Software, and Micromeritics.
  • SFW Capital Partners is a private equity firm focused on building market leading companies in the industrial and life sciences technology sector.

Nature Medicine Publishes Full Results from Axial Therapeutics’ Phase 1b/2a Clinical Trial in Autism Spectrum Disorder (ASD)

Retrieved on: 
Monday, February 14, 2022

Axial Therapeutics, a clinical-stage biopharmaceutical company dedicated to improving the lives of people with neurological disorders and conditions, today announced the publication in Nature Medicine of full results from its Phase 1b/2a clinical trial of AB-2004.

Key Points: 
  • Axial Therapeutics, a clinical-stage biopharmaceutical company dedicated to improving the lives of people with neurological disorders and conditions, today announced the publication in Nature Medicine of full results from its Phase 1b/2a clinical trial of AB-2004.
  • The article, titled Safety and target-engagement of an oral small molecule sequestrant in adolescents with Autism Spectrum Disorder: an open-label phase 1b/2a trial, is available online at https://www.nature.com/articles/s41591-022-01683-9 .
  • Based on the positive results from the Phase 1b/2a clinical trial, Axial has commenced a global, randomized, double-blind, placebo-controlled Phase 2 study of AB-2004 for the treatment of irritability associated with ASD.
  • Axials lead product candidate is AB-2004, a molecular therapeutic in Phase 2b clinical trials for the treatment of irritability in children with autism.