Seizure

• TOKYO, Jan 18, 2024 - (JCN Newswire) - Eisai Co., Ltd. announced today that it has obtained marketing authorization approval from the Japanese Ministry of Health, Labour and Welfare for the injection formulation of its in-house discovered antiepileptic drug (AED) Fycompa (perampanel) in Japan as an alternative therapy when oral administration is temporarily not possible.
• Fycompa is a first-in-class AED discovered at Eisai's Tsukuba Research Laboratories.
• Two oral formulations of Fycompa are available in Japan: a tablet and a fine granule formulation.
• Since Fycompa is the only AMPA receptor antagonist-based AED, Eisai developed this injection formulation to meet the needs of patients who are unable to use oral administration, and filed a supplementary new drug application as a new route of administration in August 2022, leading to this approval.

• Dijon, France, February 1, 2024 -- 18:15 CET - Crossject (ISIN: FR0011716265; Euronext: ALCJ), a specialty pharma company developing needle-free auto-injectors for emergency situations, will hold a conference call on its commercial strategy in the U.S. and Europe on February 6, 2024 at 17:30 CET.
• The presentation will be held in English.
• The leadership will also provide a general business update and discuss the Company’s progress towards its strategic objectives.
• To register for the webcast, please use the following details:

• But in much of the country, when winter rolls around, previously hospitable conditions can quickly turn chilly and dangerous for people and pups alike.
• Winter brings some unique challenges for dog owners, since dogs still need activity and socialization during colder seasons.
• Studies have shown that dog owners are almost 50% less likely to walk their dogs when the weather gets cold.

Breed and age differences

• A short-coated dog like a Chihuahua is much more susceptible to the dangers of cold weather than a thick-coated husky.
• Age also affects cold-weather resilience.

When is my dog too cold?

• A good rule to live by is if it is too cold for you, it is too cold for your dog.
• Getting your dog a sweater or jacket and paw covers can provide them with protection from the elements and keep them comfortable.
• Veterinarians also recommend closely monitoring your dog and limiting their time outside when the temperature nears the freezing point or drops below it.

Road salt dangers

Road salt that treats ice on streets and sidewalks can also harm dogs. When dogs walk on the salt, the sharp, rough edges of the salt crystals can irritate the sensitive skin on their paws.

• Some companies make pet-safe salt, but in public it can be hard to tell what type of salt is on the ground.
• You can also keep their paw fur trimmed to prevent snow from balling up or salt collecting in the fur.

Antifreeze risks

• Some people pour antifreeze into their toilets when away from their home to prevent the water in the toilet from freezing.
• Antifreeze is an exceptionally dangerous chemical to dogs and cats, as it tastes sweet but can be deadly when ingested.
• If a pet ingests even a small amount of antifreeze, the substance causes a chemical cascade in their body that results in severe kidney damage.

Erik Christian Olstad does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

• Old Glory Bank’s co-founder John Rich had this to say about the federal government’s intrusion into Americans’ personal banking transactions, as uncovered by the Congressional Select Committee on the Weaponization of the Federal Government.
• A lot of patriots built Old Glory Bank to be an option from the woke federally controlled banking system we have in this country right now.
• “The whole theme behind Old Glory Bank is that you will not be penalized for exercising your Constitutional rights.
• Old Glory Bank is committed to serving those who feel marginalized for believing in the greatness of America.