Organophosphate

Enhancing National Preparedness: Rafa Laboratories Partners with BARDA to Advance the Development of a new design for Rafa's Pediatric Atropine Autoinjectors

Retrieved on: 
Wednesday, March 20, 2024
Development, Poisoning, Organophosphate, VX, Status epilepticus, Patient, Nerve agent, Clothing, Laboratory, Human services, Atropine, Sarin, Administration, FDA

Atropine - the primary antidote for nerve agent and insecticide poisoning, is usually administered via autoinjectors.

Key Points: 
  • Atropine - the primary antidote for nerve agent and insecticide poisoning, is usually administered via autoinjectors.
  • Rafa Laboratories already manufactures adult atropine autoinjectors, FDA-approved in July 2018, and pediatric atropine autoinjectors authorized for use under FDA Emergency Use Authorization (EUA) in January 2018.
  • The new design for the pediatric atropine autoinjector, which is intended for civilian use, will incorporate a new needle shield mechanism feature.
  • To meet FDA approval requirements for the enhanced pediatric atropine autoinjector, BARDA will provide comprehensive support to Rafa Laboratories.

Enhancing National Preparedness: Rafa Laboratories Partners with BARDA to Advance the Development of a new design for Rafa's Pediatric Atropine Autoinjectors

Retrieved on: 
Wednesday, March 20, 2024
Development, Poisoning, Organophosphate, VX, Status epilepticus, Patient, Nerve agent, Clothing, Laboratory, Human services, Atropine, Sarin, Administration, FDA

Atropine - the primary antidote for nerve agent and insecticide poisoning, is usually administered via autoinjectors.

Key Points: 
  • Atropine - the primary antidote for nerve agent and insecticide poisoning, is usually administered via autoinjectors.
  • Rafa Laboratories already manufactures adult atropine autoinjectors, FDA-approved in July 2018, and pediatric atropine autoinjectors authorized for use under FDA Emergency Use Authorization (EUA) in January 2018.
  • The new design for the pediatric atropine autoinjector, which is intended for civilian use, will incorporate a new needle shield mechanism feature.
  • To meet FDA approval requirements for the enhanced pediatric atropine autoinjector, BARDA will provide comprehensive support to Rafa Laboratories.

Marinus Pharmaceuticals Announces Exercise of First Contract Option by the Biomedical Advanced Research and Development Authority (BARDA)

Retrieved on: 
Thursday, September 22, 2022
Pharmaceutical, Health, Neurology, Biometrics, Adult, Organophosphate, Therapy, RAISE, Safety, Development, IV, COVID-19, Epilepsy, Seizure, GABAA, Brain, FDA, Office of Inspector General, U.S. Department of Health and Human Services, BARDA, Ganaxolone, Administration, Lists of weapons, Private Securities Litigation Reform Act, Forward-looking statement, SE, U.S. Securities and Exchange Commission, Status epilepticus, Patient, Clinical trial, U.S. Department of Defense Strategy for Operating in Cyberspace, Benzodiazepine, Human services, Medication, API, Biomedical Advanced Research and Development Authority, Security (finance), CDKL5, EMA, CV, Pharmaceutical industry, RSE

This contract option was exercised under Marinus ongoing cost-share contract with BARDA awarded in 2020 to support the development of intravenous (IV) ganaxolone for the treatment of refractory status epilepticus (RSE).

Key Points: 
  • This contract option was exercised under Marinus ongoing cost-share contract with BARDA awarded in 2020 to support the development of intravenous (IV) ganaxolone for the treatment of refractory status epilepticus (RSE).
  • Refractory status epilepticus is a life-threatening condition in which a significant number of patients do not respond to first- and second-line anticonvulsant drugs.
  • Ganaxolone development in the RAISE trial is being funded in part with federal funds from BARDA under contract number 75A50120C00159.
  • Any forward-looking statements that we make in this press release speak only as of the date of this press release.

BioConsortia Showcases Breakthrough Microbial Products and Pipeline of Innovation

Retrieved on: 
Thursday, September 1, 2022
Technology, Manufacturing, Food, Beverage, Agriculture, Natural Resources, Research, Retail, Agritech, Engineering, Science, Chemicals, Plastics, Well, Nematicide, Nitrogen fixation, CA, Plant, Technology, Food, CEO, Showcase, Vegetable, Soil, Standard Barrel Act For Fruits, Vegetables, and Dry Commodities, Agriculture, River, Engineering, Protein, Carbamate, Toxicity, Solution, The Mosaic Company, UN, Senior, Fertilizer, Organophosphate, Lake, Multimedia, FAO, Eutrophication, Fertility, Genetically modified bacteria, AMS, Face, Nitrogen, Industry, Health, Fruit, Environment, Marketing, Adoption, Efficiency, Oil, Research

BioConsortia is fundamentally a discovery and optimization company, designing microbial products to solve the challenges we must meet in order to feed a hungry world, said CEO, Meadows-Smith.

Key Points: 
  • BioConsortia is fundamentally a discovery and optimization company, designing microbial products to solve the challenges we must meet in order to feed a hungry world, said CEO, Meadows-Smith.
  • BioConsortia, Inc. develops superior microbial products that protect plants, enhance fertility, and increase yields while improving the sustainability of agriculture for our environment.
  • BioConsortias microbial products deliver superior efficacy, higher consistency, and easier grower adoption.
  • BioConsortia is producing breakthrough solutions for growers in major agricultural markets with multiple environmental benefits.

Southeastern Grocers Announces Commitment to the Health of Pollinators

Retrieved on: 
Thursday, August 18, 2022
Environmental Health, Women, Men, Sustainability, Wine & Spirits, Family, Supermarket, Public Policy, Government, Animal Welfare, Consumer, Environmental, Social and Governance (ESG), Organic Food, Food, Beverage, Environment, Retail, Professional Services, Agriculture, Other Consumer, Natural Resources, Environmental Issues, Honey, Harveys Supermarkets, IPM, Multimedia, Food security, Butterfly, National Organic Program, Neonicotinoid, U.S. Department of Agriculture Cotton Annex, Human, Bird, USDA, Winn-Dixie, U.S. Department of Defense Strategy for Operating in Cyberspace, Organophosphate, Pesticide, Pharmacy, Health, SEG, Grocery store, Animal husbandry, Agriculture, Southeastern Grocers

Southeastern Grocers Inc. (SEG), parent company and home of Fresco y Ms, Harveys Supermarket and Winn-Dixie grocery stores, announces its commitment to protect the health of the worlds essential pollinator populations and do its part to ensure food security for future generations.

Key Points: 
  • Southeastern Grocers Inc. (SEG), parent company and home of Fresco y Ms, Harveys Supermarket and Winn-Dixie grocery stores, announces its commitment to protect the health of the worlds essential pollinator populations and do its part to ensure food security for future generations.
  • View the full release here: https://www.businesswire.com/news/home/20220818005197/en/
    Southeastern Grocers announces its commitment to protect the health of the worlds essential pollinator populations and do its part to ensure food security for future generations.
  • Steve Williams, Vice President of Produce and Floral for Southeastern Grocers, said, At Southeastern Grocers, we are committed to the development of lasting change, especially when it comes to safeguarding the worlds food supply for our future generations.
  • SEGs Pollinator Health Policy commits to engaging with supplier partners to establish clear objectives resulting in healthier environments for pollinators.

New Kid on the Block: Cerium Oxide Nanozyme Joins the Pesticide Detection Taskforce, According to Journal of Pharmaceutical Analysis Study

Retrieved on: 
Tuesday, January 18, 2022
Plant, Research, Human, Pesticide, Carbon, University of Macau, University, Concentration ratio, Adoption, Solution, Adenophora, Method, Food, Neuro, Organophosphate, Medicine, Catalysis, Institute, Agriculture, Rare-earth element

In this regard, a group of scientists in China have taken up the baton to advance pharmaceutical analysis of organophosphates in plants, beginning with methyl-paraoxon.

Key Points: 
  • In this regard, a group of scientists in China have taken up the baton to advance pharmaceutical analysis of organophosphates in plants, beginning with methyl-paraoxon.
  • Dr. Li explains, "Under the optimized conditions, we achieved desirable recoveries for different herbal samples using cerium oxide nanozyme.
  • Using methods like cyclic voltammetry, they confirmed that there is significant signal enhancement owing to the presence of cerium oxide nanozyme.
  • Overall, the study has paved the way for advanced research on effective detection of pesticides in various materials used for human consumption.

Insect Pest Control Market worth $15.8 billion by 2026 - Exclusive Report by MarketsandMarkets™

Retrieved on: 
Monday, September 13, 2021
Bed, Bed bug, Pest control, Chemical substance, Carbamate, BASF, Fever Dream, Encephalitis, Dry, Hydrocarbon, Yellow fever, WNV, CAGR, Health, Neonicotinoid, Climate, Animal, Marketing, Malaria, EEE, USD, FMC Corporation, Region, West Nile virus, Ant, Growth, Pyrrole, Virus, Synthetic control method, Population, Human, Insect, Spray, Commercial, Organophosphate, Method, Agriculture, Trapping, Fine chemical

The change in climate conditions is a significant factor that has contributed to the growth of the insect pest control market.

Key Points: 
  • The change in climate conditions is a significant factor that has contributed to the growth of the insect pest control market.
  • This is expected to be a major driver for the growth of the insect pest control market.
  • Due to strict rules and regulations and an increase in health-conscious consumers has led to the increased use of insect pest control services and has offered a market opportunity for the insect pest control market.
  • The chemical control method dominates the insect pest control market with the largest share in 2021.

Insect Pest Control Market worth $15.8 billion by 2026 - Exclusive Report by MarketsandMarkets™

Retrieved on: 
Monday, September 13, 2021
Bed, Bed bug, Pest control, Chemical substance, Carbamate, BASF, Fever Dream, Encephalitis, Dry, Hydrocarbon, Yellow fever, WNV, CAGR, Health, Neonicotinoid, Climate, Animal, Marketing, Malaria, EEE, USD, FMC Corporation, Region, West Nile virus, Ant, Growth, Pyrrole, Virus, Synthetic control method, Population, Human, Insect, Spray, Commercial, Organophosphate, Method, Agriculture, Trapping, Fine chemical

The change in climate conditions is a significant factor that has contributed to the growth of the insect pest control market.

Key Points: 
  • The change in climate conditions is a significant factor that has contributed to the growth of the insect pest control market.
  • This is expected to be a major driver for the growth of the insect pest control market.
  • Due to strict rules and regulations and an increase in health-conscious consumers has led to the increased use of insect pest control services and has offered a market opportunity for the insect pest control market.
  • The chemical control method dominates the insect pest control market with the largest share in 2021.

Nutra Pharma Files Updated Provisional Patent for Nerve Agent Counter Measures

Retrieved on: 
Friday, July 23, 2021
Branches of biology, Anatomy, Neuroscience, Acetylcholinesterase inhibitors, Nerve agent, Organophosphate, Nerve, Neuron

"We originally announced this project in early 2018, stated Rik J Deitsch, Chief Executive Officer of Nutra Pharma.

Key Points: 
  • "We originally announced this project in early 2018, stated Rik J Deitsch, Chief Executive Officer of Nutra Pharma.
  • Nerve agents are identified as a class of phosphorus-containing organic chemicals (organophosphates) that may disrupt the transfer of messages to organs through the nerves.
  • These same receptors are the target of Nutra Pharmas drugs, which may block the action of the nerve agents or minimize the damage that they may cause.
  • Scientific publications have demonstrated that native and modified neurotoxins can protect nerve cells from early cell death.

HJF Receives Patent for Potential Treatment for Nerve Agent Exposure

Retrieved on: 
Tuesday, May 11, 2021
Drugs, Acetylcholinesterase inhibitors, Psychoactive drugs, Medicine, Antidotes, Nerve agent, Atropine, Organophosphate, Anticholinergic, Henry M. Jackson Foundation for the Advancement of Military Medicine, Autoinjector

b"BETHESDA, Md., May 11, 2021 /PRNewswire/ --The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) received notice of allowance for a patent from the United States Patent Office (USPO) for a medical countermeasure to organophosphate (OP) nerve agent exposure.

Key Points: 
  • b"BETHESDA, Md., May 11, 2021 /PRNewswire/ --The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) received notice of allowance for a patent from the United States Patent Office (USPO) for a medical countermeasure to organophosphate (OP) nerve agent exposure.
  • The therapy was shown to be effective even with delayed use following nerve agent exposure.
  • Currently, treatment for OP exposure is with an anticholinergic agent administered immediately after exposure; thus, military personnel may receive kits containing atropine auto-injectors for use in the event of a nerve-gas attack.\nDr.
  • Importantly, this new combination therapy also extends the therapeutic window, as it is effective even when administered hours after OP exposure.