TheraSphere

Bruce Power to explore production of cancer-fighting medical isotope yttrium-90 for global distribution

Retrieved on: 
Monday, October 3, 2022

Medical isotopes save lives and Ontario is primed to become an isotope superpower, said Ontarios Energy Minister Todd Smith.

Key Points: 
  • Medical isotopes save lives and Ontario is primed to become an isotope superpower, said Ontarios Energy Minister Todd Smith.
  • Additionally, Bruce Power will soon become the first nuclear power reactor operator to commercially produce lutetium-177 through an innovative Isotope Production System (IPS).
  • The IPS is a first-of-its-kind solution to produce short-lived medical isotopes in a commercial reactor and will provide unprecedented capacity, redundancy and scale for medical isotope production.
  • Isogen will also work with Bruce Power and Boston Scientific on the feasibility of yttrium-90 production using the IPS.

Boston Scientific Receives FDA Approval for TheraSphere™ Y-90 Glass Microspheres

Retrieved on: 
Thursday, March 18, 2021

MARLBOROUGH, Mass., March 18, 2021 /PRNewswire/ --Boston Scientific Corporation (NYSE: BSX) announced it has received U.S. Food and Drug Administration (FDA) approval of the TheraSphere Y-90 Glass Microspheres, developed for the treatment of patients with hepatocellular carcinoma (HCC).

Key Points: 
  • MARLBOROUGH, Mass., March 18, 2021 /PRNewswire/ --Boston Scientific Corporation (NYSE: BSX) announced it has received U.S. Food and Drug Administration (FDA) approval of the TheraSphere Y-90 Glass Microspheres, developed for the treatment of patients with hepatocellular carcinoma (HCC).
  • TheraSphere treatment, a type of SIRT with low toxicity, is comprised of millions of microscopic glass beads containing radioactive yttrium (Y-90), which are delivered directly to liver tumors via catheter and result in minimal exposure to surrounding healthy tissue.
  • Approval of TheraSphere was based on results from the LEGACY study, designed to evaluate the safety and efficacy of the therapy for the treatment of early and advanced HCC.
  • Boston Scientific transforms lives through innovative medical solutions that improve the health of patients around the world.

CIRT-EU Registry for SIR-Spheres® Therapy presented at CIRSE 2020 Summit

Retrieved on: 
Tuesday, September 15, 2020

"I am extremely proud of the CIRSE team for their hard work the last six years to successfully complete this registry," said Helmberger.

Key Points: 
  • "I am extremely proud of the CIRSE team for their hard work the last six years to successfully complete this registry," said Helmberger.
  • CIRT EU is the largest observational registry run exclusively by CIRSE and funded by a grant provided by Sirtex Medical Europe.
  • Sirtex's current lead product is a targeted radiation therapy for liver cancer called SIR-Spheres Y-90 resin microspheres.
  • Selective internal radiation therapy (SIRT) with SIR-Spheres Y-90 resin microspheres is a prescription device for the treatment of inoperable liver tumours.

CIRT-EU Registry for SIR-Spheres® Therapy presented at CIRSE 2020 Summit

Retrieved on: 
Tuesday, September 15, 2020

"I am extremely proud of the CIRSE team for their hard work the last six years to successfully complete this registry," said Helmberger.

Key Points: 
  • "I am extremely proud of the CIRSE team for their hard work the last six years to successfully complete this registry," said Helmberger.
  • CIRT EU is the largest observational registry run exclusively by CIRSE and funded by a grant provided by Sirtex Medical Europe.
  • Sirtex's current lead product is a targeted radiation therapy for liver cancer called SIR-Spheres Y-90 resin microspheres.
  • Selective internal radiation therapy (SIRT) with SIR-Spheres Y-90 resin microspheres is a prescription device for the treatment of inoperable liver tumours.

Sirtex Medical Launches State-of-the-Art SIROS™ System for Advanced SIR-Spheres® Resin Microspheres Delivery

Retrieved on: 
Monday, August 3, 2020

Sirtex Medical US Holdings, Inc. (Sirtex), a leading manufacturer of targeted liver cancer therapies, announced the launch of SIROS , an innovative system for the delivery of SIR-Spheres Y-90 resin microspheres.

Key Points: 
  • Sirtex Medical US Holdings, Inc. (Sirtex), a leading manufacturer of targeted liver cancer therapies, announced the launch of SIROS , an innovative system for the delivery of SIR-Spheres Y-90 resin microspheres.
  • With the systems visually controlled administration, physicians can determine and adjust the precise quantity and speed of SIR-Spheres microspheres delivery.
  • Additionally, the system is designed to be simple to use yet versatile enough to allow expanded options for patient-tailored delivery.
  • Sirtexs current lead product is a targeted radiation therapy for liver cancer called SIR-Spheres Y-90 resin microspheres.

Recommendations for Personalised HCC Treatment With Y90 TheraSphere™ Published by an International Multidisciplinary Group

Retrieved on: 
Tuesday, July 23, 2019

LONDON, July 23, 2019 /PRNewswire/ -- BTG plc (LSE: BTG), a global healthcare company, today announced consensus recommendations for personalised treatment for hepatocellular carcinoma (HCC) with TheraSphere have been published by an international multidisciplinary working group1.

Key Points: 
  • LONDON, July 23, 2019 /PRNewswire/ -- BTG plc (LSE: BTG), a global healthcare company, today announced consensus recommendations for personalised treatment for hepatocellular carcinoma (HCC) with TheraSphere have been published by an international multidisciplinary working group1.
  • Higher response rates of 71% were seen in the personalised prospective dosimetry arm vs 36% with standard dosimetry.
  • "The working group reached a consensus recommendation on simple, reproducible and evidence-based practice for personalised treatment of HCC patients with TheraSphere.
  • We provide high value patient-centric treatment options which include locally-applied embolisation, radiotherapy with Y90 glass microspheres and cryoablation.

Recommendations for Personalised HCC Treatment With Y90 TheraSphere™ Published by an International Multidisciplinary Group

Retrieved on: 
Tuesday, July 23, 2019

Higher response rates of 71% were seen in the personalised prospective dosimetry arm vs 36% with standard dosimetry.

Key Points: 
  • Higher response rates of 71% were seen in the personalised prospective dosimetry arm vs 36% with standard dosimetry.
  • "The working group reached a consensus recommendation on simple, reproducible and evidence-based practice for personalised treatment of HCC patients with TheraSphere.
  • For each scenario, recommendations are provided on patient selection, treatment planning and dosimetry, treatment delivery and outcome assessment and degree of recommendation and the strength of consensus.
  • We provide high value patient-centric treatment options which include locally-applied embolisation, radiotherapy with Y90 glass microspheres and cryoablation.